Structure of human B12 trafficking protein CblD reveals molecular mimicry and identifies a new subfamily of nitro-FMN reductases

Journal of Biological Chemistry

Volumn 290, Issue 49, 2015, Pages 29155-29166

  Yamada, Kazuhiro ^a   Gherasim, Carmen ^b   Banerjee, Ruma ^b   Koutmos, Markos ^a  

^a Uniformed Services University of the Health Sciences   (United States)

^b UNIVERSITY OF MICHIGAN MEDICAL SCHOOL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AMINO ACIDS; CHEMICAL ACTIVATION; ENZYME ACTIVITY; PROTEINS; REACTION KINETICS;

ACTIVATION DOMAIN; C-TERMINAL DOMAINS; INTRACELLULAR PATHWAYS; METHIONINE SYNTHASE; METHYLMALONIC ACIDURIA; METHYLMALONYL-COA MUTASE; REDUCTIVE DEHALOGENASES; STRUCTURAL SIMILARITY;

CRYSTAL STRUCTURE;

CARRIER PROTEIN; CBLC PROTEIN; CBLD PROTEIN; COBALAMIN; CYANOCOBALAMIN; FLAVINE MONONUCLEOTIDE REDUCTASE; METHIONINE SYNTHASE; NITRO FMN REDUCTASE; UNCLASSIFIED DRUG; 5 METHYLTETRAHYDROFOLATE HOMOCYSTEINE METHYLTRANSFERASE; LIGAND; MMADHC PROTEIN, HUMAN; OXYGEN;

ARTICLE; CARBOXY TERMINAL SEQUENCE; CHEMICAL REACTION KINETICS; CONTROLLED STUDY; CRYSTAL STRUCTURE; HUMAN; MOLECULAR MIMICRY; MUTATION; NONHUMAN; OXIDATION; PRIORITY JOURNAL; PROTEIN FOLDING; PROTEIN PROTEIN INTERACTION; PROTEIN STRUCTURE; AMINO ACID SEQUENCE; CHEMISTRY; CYTOPLASM; GENETICS; HOMOCYSTINURIA; LYSOSOME; METABOLISM; MISSENSE MUTATION; MOLECULAR GENETICS; PROTEIN CONFORMATION; PROTEIN MOTIF; PROTEIN SECONDARY STRUCTURE; PROTEIN TRANSPORT; SEQUENCE HOMOLOGY; X RAY CRYSTALLOGRAPHY; X RAY DIFFRACTION;

5-METHYLTETRAHYDROFOLATE-HOMOCYSTEINE S-METHYLTRANSFERASE; AMINO ACID MOTIFS; AMINO ACID SEQUENCE; CRYSTALLOGRAPHY, X-RAY; CYTOPLASM; FMN REDUCTASE; HOMOCYSTINURIA; HUMANS; LIGANDS; LYSOSOMES; MITOCHONDRIAL MEMBRANE TRANSPORT PROTEINS; MOLECULAR MIMICRY; MOLECULAR SEQUENCE DATA; MUTATION; MUTATION, MISSENSE; OXYGEN; PROTEIN CONFORMATION; PROTEIN FOLDING; PROTEIN STRUCTURE, SECONDARY; PROTEIN TRANSPORT; SEQUENCE HOMOLOGY, AMINO ACID; VITAMIN B 12; X-RAY DIFFRACTION;

EID: 84949034269     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M115.682435     Document Type: Article

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