A human vitamin B12 trafficking protein uses glutathione transferase activity for processing alkylcobalamins

Journal of Biological Chemistry

Volumn 284, Issue 48, 2009, Pages 33418-33424

  Kim, Jihoe ^a,e   Hannibal, Luciana ^b,c   Gherasim, Carmen ^a   Jacobsen, Donald W ^b,c,d   Banerjee, Ruma ^a  

^a UNIVERSITY OF MICHIGAN HEALTH SYSTEM   (United States)

^b LERNER RESEARCH INSTITUTE   (United States)

^c KENT STATE UNIVERSITY   (United States)

^d CASE WESTERN RESERVE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^e Yeungnam University   (South Korea)

Author keywords

[No Author keywords available]

Indexed keywords

ALKYL GROUPS; CATALYTIC TURNOVER; COFACTORS; CYTOSOLIC; DEALKYLATION; GLUTATHIONE TRANSFERASE; GLUTATHIONES; HOMOCYSTEINES; METHIONINE SYNTHASE; METHYLTRANSFERASES; NUCLEOPHILIC DISPLACEMENT; THIOETHERS; THIOLATES; VITAMIN B;

CHEMICAL REACTIONS; FLUORINE CONTAINING POLYMERS; MAMMALS; PROTEINS; VITAMINS;

ENZYMES;

COBALAMIN; CYANOCOBALAMIN; GLUTATHIONE TRANSFERASE; ALKANE; CARRIER PROTEIN; COBALT; COBAMAMIDE; DRUG DERIVATIVE; GLUTATHIONE; MECOBALAMIN; MMACHC PROTEIN, HUMAN; THIOL DERIVATIVE;

ARTICLE; CONTROLLED STUDY; ENZYME ACTIVE SITE; ENZYME ACTIVITY; GENE MUTATION; HUMAN; HUMAN CELL; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN BINDING; PROTEIN METABOLISM; PROTEIN PURIFICATION; PROTEIN TRANSPORT; BIOLOGICAL MODEL; CATALYSIS; CELL CULTURE; CYTOLOGY; ELECTROSPRAY MASS SPECTROMETRY; FIBROBLAST; GENETICS; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; METABOLISM; MUTATION; TRANSPORT AT THE CELLULAR LEVEL;

MAMMALIA;

ALKANES; BIOLOGICAL TRANSPORT; CARRIER PROTEINS; CATALYSIS; CELLS, CULTURED; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; COBALT RADIOISOTOPES; COBAMIDES; FIBROBLASTS; GLUTATHIONE; GLUTATHIONE TRANSFERASE; HUMANS; MODELS, BIOLOGICAL; MUTATION; SPECTROMETRY, MASS, ELECTROSPRAY IONIZATION; SULFHYDRYL COMPOUNDS; VITAMIN B 12;

EID: 70450242681     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M109.057877     Document Type: Article

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