Insights into the reactivation of cobalamin-dependent methionine synthase

Proceedings of the National Academy of Sciences of the United States of America

Volumn 106, Issue 44, 2009, Pages 18527-18532

  Koutmos, Markos ^a   Datta, Supratim ^a   Pattridge, Katherine A ^a   Smith, Janet L ^a,b   Matthews, Rowena G ^a,b  

^a UNIVERSITY OF MICHIGAN   (United States)

^b UNIVERSITY OF MICHIGAN MEDICAL SCHOOL   (United States)

Author keywords

Cob(II)alamin coordination; Corrinoid methyltransferase; Enzyme catalysis; Multimodular protein; Protein conformation

Indexed keywords

CBL PROTEIN; FLAVODOXIN; HYDROXOCOBALAMIN; METHIONINE SYNTHASE; S ADENOSYLHOMOCYSTEINE; TYROSINE;

ARTICLE; ELECTRON TRANSPORT; ENZYME REACTIVATION; ENZYME STRUCTURE; PRIORITY JOURNAL; PROTEIN STABILITY; X RAY ANALYSIS;

5-METHYLTETRAHYDROFOLATE-HOMOCYSTEINE S-METHYLTRANSFERASE; AMINO ACID SUBSTITUTION; CATALYTIC DOMAIN; COBALT; ENZYME ACTIVATION; ESCHERICHIA COLI; MODELS, BIOLOGICAL; MODELS, MOLECULAR; MUTATION; OXIDATION-REDUCTION; PROTEIN STRUCTURE, SECONDARY; S-ADENOSYLHOMOCYSTEINE; SPECTRUM ANALYSIS; VITAMIN B 12;

EID: 70350422423     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.0906132106     Document Type: Article

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