Structural basis of multifunctionality in a vitamin B 12- processing enzyme

Journal of Biological Chemistry

Volumn 286, Issue 34, 2011, Pages 29780-29787

  Koutmos, Markos ^a   Gherasim, Carmen ^a   Smith, Janet L ^a   Banerjee, Ruma ^a  

^a UNIVERSITY OF MICHIGAN HEALTH SYSTEM   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

DEALKYLATION; EVOLUTIONARY ADAPTATION; FLAVIN REDUCTASE; GLUTATHIONE TRANSFERASE; MECHANISM OF ACTION; METHYLMALONIC ACIDURIA; MULTIFUNCTIONALITY; PATHOLOGICAL MUTATIONS; PROSTHETIC GROUPS; STRUCTURAL BASIS; STRUCTURAL PLATFORM; VITAMIN B;

SCAFFOLDS;

ENZYME ACTIVITY;

CYANOCOBALAMIN; FLAVINE ADENINE NUCLEOTIDE; FLAVINE MONONUCLEOTIDE; FLAVINE MONONUCLEOTIDE REDUCTASE; GLUTATHIONE TRANSFERASE; MECOBALAMIN; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE;

AMINO ACID SEQUENCE; ANIMAL TISSUE; ARTICLE; BIOCHEMISTRY; CONFORMATIONAL TRANSITION; CONTROLLED STUDY; DEALKYLATION; ENZYME ACTIVITY; ENZYME MECHANISM; ENZYME STRUCTURE; MOUSE; NONHUMAN; PHENOTYPE; PRIORITY JOURNAL; PROTEIN FAMILY;

CATALYSIS; CRYSTALLOGRAPHY, X-RAY; FLAVIN MONONUCLEOTIDE; FLAVIN-ADENINE DINUCLEOTIDE; HUMANS; HYDROLASES; PROTEIN STRUCTURE, TERTIARY; STRUCTURE-ACTIVITY RELATIONSHIP; VITAMIN B 12;

EID: 80051946352     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M111.261370     Document Type: Article

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