Reductive dehalogenase structure suggests a mechanism for B12-dependent dehalogenation

Nature

Volumn 517, Issue 7535, 2015, Pages 513-516

  Payne, Karl A P ^a   Quezada, Carolina P ^a   Fisher, Karl ^a   Dunstan, Mark S ^a   Collins, Fraser A ^a   Sjuts, Hanno ^a,b   Levy, Colin ^a   Hay, Sam ^a   Rigby, Stephen E J ^a   Leys, David ^a  

^a UNIVERSITY OF MANCHESTER   (United Kingdom)

^b GOETHE UNIVERSITY   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

CYANOCOBALAMIN; ORGANOHALOGEN DERIVATIVE; OXIDOREDUCTASE; POLYCHLORINATED BIPHENYL; TRANSFER RNA; 2,6-DIBROMOPHENOL; COBALT; OXYGEN; PHENOL DERIVATIVE;

AMINO TERMINAL SEQUENCE; ARTICLE; BIOCATALYSIS; DEHALOGENATION; DENSITY FUNCTIONAL THEORY; ELECTRON SPIN RESONANCE; ELECTRON TRANSPORT; ENZYME ACTIVITY; ENZYME MECHANISM; ENZYME MODIFICATION; ENZYME SPECIFICITY; ENZYME STRUCTURE; ENZYME SUBSTRATE; HETEROLOGOUS EXPRESSION; HUMAN; HYDROGEN BOND; OXIDATION REDUCTION STATE; PRIORITY JOURNAL; CHEMICAL STRUCTURE; CHEMISTRY; ENZYMOLOGY; HALOGENATION; METABOLISM; OXIDATION REDUCTION REACTION; PHYLLOBACTERIACEAE; PROTEIN CONFORMATION; SOLUBILITY; X RAY CRYSTALLOGRAPHY;

BIOCATALYSIS; COBALT; CRYSTALLOGRAPHY, X-RAY; ELECTRON SPIN RESONANCE SPECTROSCOPY; HALOGENATION; MODELS, MOLECULAR; OXIDATION-REDUCTION; OXIDOREDUCTASES; OXYGEN; PHENOLS; PHYLLOBACTERIACEAE; PROTEIN CONFORMATION; SOLUBILITY; VITAMIN B 12;

EID: 84925494212     PISSN: 00280836     EISSN: 14764687     Source Type: Journal    
DOI: 10.1038/nature13901     Document Type: Article

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