Nanoparticle-Delivered Antisense MicroRNA-21 Enhances the Effects of Temozolomide on Glioblastoma Cells

Molecular Pharmaceutics

Volumn 12, Issue 12, 2015, Pages 4509-4517

  Ananta, Jeyarama S ^a   Paulmurugan, Ramasamy ^a,b   Massoud, Tarik F ^a  

^a STANFORD UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b STANFORD UNIVERSITY MEDICAL CENTER   (United States)

Author keywords

antisense miR 21; GBM; microRNA 21; nanoparticle; PLGA; temozolomide

Indexed keywords

CASPASE 3; COMPLEMENTARY RNA; MICRORNA 21; NANOPARTICLE; PHOSPHATIDYLINOSITOL 3,4,5 TRISPHOSPHATE 3 PHOSPHATASE; POLYGLACTIN; PROTEIN BAX; PROTEIN BCL 2; TEMOZOLOMIDE; ALKYLATING AGENT; DACARBAZINE; MICRORNA; MIRN21 MICRORNA, HUMAN; NUCLEIC ACID PROBE; PTEN PROTEIN, HUMAN;

ARTICLE; CELL PROLIFERATION; CELL VIABILITY; CONTROLLED STUDY; DOWN REGULATION; G2 PHASE CELL CYCLE CHECKPOINT; GENE OVEREXPRESSION; GENE SILENCING; GLIOBLASTOMA CELL LINE; HYDRODYNAMICS; IMMUNOBLOTTING; M PHASE CELL CYCLE CHECKPOINT; MTT ASSAY; PRIORITY JOURNAL; QUANTITATIVE ANALYSIS; REAL TIME POLYMERASE CHAIN REACTION; SCANNING ELECTRON MICROSCOPY; ANALOGS AND DERIVATIVES; BRAIN NEOPLASMS; DRUG EFFECTS; GENE EXPRESSION REGULATION; GENETICS; GLIOBLASTOMA; GLIOMA; HUMAN; NUCLEIC ACID PROBE; TUMOR CELL LINE;

ANTINEOPLASTIC AGENTS, ALKYLATING; ANTISENSE ELEMENTS (GENETICS); BRAIN NEOPLASMS; CASPASE 3; CELL LINE, TUMOR; DACARBAZINE; GENE EXPRESSION REGULATION, NEOPLASTIC; GLIOBLASTOMA; GLIOMA; HUMANS; MICRORNAS; NANOPARTICLES; PTEN PHOSPHOHYDROLASE;

EID: 84948984126     PISSN: 15438384     EISSN: 15438392     Source Type: Journal    
DOI: 10.1021/acs.molpharmaceut.5b00694     Document Type: Article

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