Macrophage responses to implants: Prospects for personalized medicine

Journal of Leukocyte Biology

Volumn 98, Issue 6, 2015, Pages 953-962

  Kzhyshkowska, Julia ^a,b,c   Gudima, Alexandru ^a   Riabov, Vladimir ^a,c   Dollinger, Camille ^d   Lavalle, Philippe ^e,f   Vrana, Nihal Engin ^d  

^a UNIVERSITY OF HEIDELBERG   (Germany)

^b German Red Cross Transfusion Service Baden Württemberg   (Germany)

^c TOMSK STATE UNIVERSITY   (Russian Federation)

^d PROTIP MEDICAL   (France)

^e INSERM   (France)

^f UNIVERSITÉ DE STRASBOURG   (France)

Author keywords

Biomarker; Biomaterial; Coating; Cytokine; Titanium

Indexed keywords

ANTIINFLAMMATORY AGENT; BIOLOGICAL MARKER; BIOMATERIAL; CYTOKINE; POLYMER;

CELL INTERACTION; CHRONIC INFLAMMATION; CYTOKINE PRODUCTION; EX VIVO STUDY; HUMAN; IMMUNE RESPONSE; IMMUNOMODULATION; IMPLANT; INFECTION; INFLAMMATION; MACROPHAGE; MACROPHAGE ACTIVATION; MATERIAL COATING; MICROBIAL CONTAMINATION; NONHUMAN; PERSONALIZED MEDICINE; PHAGOCYTOSIS; PHENOTYPE; PRIORITY JOURNAL; REVIEW; ADVERSE EFFECTS; ANIMAL; FOREIGN-BODY REACTION; IMMUNOLOGY; PATHOLOGY; PROCEDURES; PROSTHESES AND ORTHOSES; SURFACE PROPERTY;

ANIMALS; COATED MATERIALS, BIOCOMPATIBLE; FOREIGN-BODY REACTION; HUMANS; MACROPHAGES; PHAGOCYTOSIS; PRECISION MEDICINE; PROSTHESES AND IMPLANTS; SURFACE PROPERTIES;

EID: 84948977220     PISSN: 07415400     EISSN: 19383673     Source Type: Journal    
DOI: 10.1189/jlb.5VMR0415-166R     Document Type: Review

References (92)

1. Goodman, S. B., Yao, Z., Keeney, M., Yang, F. (2013) The future of biologic coatings for orthopaedic implants. Biomaterials 34, 3174–3183.
2. Zorlutuna, P., Vrana, N. E., Khademhosseini, A. (2013) The expanding world of tissue engineering: the building blocks and new applications of tissue engineered constructs. IEEE Rev. Biomed. Eng. 6, 47–62.
3. Elloumi-Hannachi, I., Yamato, M., Okano, T. (2010) Cell sheet engineering: a unique nanotechnology for scaffold-free tissue reconstruction with clinical applications in regenerative medicine. J. Intern. Med. 267, 54–70.
4. Brown, B. N., Ratner, B. D., Goodman, S. B., Amar, S., Badylak, S. F. (2012) Macrophage polarization: an opportunity for improved outcomes in biomaterials and regenerative medicine. Biomaterials 33, 3792–3802.
5. Gordon, S., Martinez, F. O. (2010) Alternative activation of macrophages: mechanism and functions. Immunity 32, 593–604.
6. Stein, M., Keshav, S., Harris, N., Gordon, S. (1992) Interleukin 4 potently enhances murine macrophage mannose receptor activity: a marker of alternative immunologic macrophage activation. J. Exp. Med. 176, 287–292.
7. Goerdt, S., Orfanos, C. E. (1999) Other functions, other genes: alternative activation of antigen-presenting cells. Immunity 10, 137–142.
8. Martinez, F. O., Sica, A., Mantovani, A., Locati, M. (2008) Macrophage activation and polarization. Front. Biosci. 13, 453–461.
9. Stout, R. D., Jiang, C., Matta, B., Tietzel, I., Watkins, S. K., Suttles, J. (2005) Macrophages sequentially change their functional phenotype in response to changes in microenvironmental influences. J. Immunol. 175, 342–349.
10. Gratchev, A., Kzhyshkowska, J., Köthe, K., Muller-Molinet, I., Kannookadan, S., Utikal, J., Goerdt, S. (2006) Mphi1 and Mphi2 can be re-polarized by Th2 or Th1 cytokines, respectively, and respond to exogenous danger signals. Immunobiology 211, 473–486.
11. Murray, P. J., Allen, J. E., Biswas, S. K., Fisher, E. A., Gilroy, D. W., Goerdt, S., Gordon, S., Hamilton, J. A., Ivashkiv, L. B., Lawrence, T., Locati, M., Mantovani, A., Martinez, F. O., Mege, J. L., Mosser, D. M., Natoli, G., Saeij, J. P., Schultze, J. L., Shirey, K. A., Sica, A., Suttles, J., Udalova, I., van Ginderachter, J. A., Vogel, S. N., Wynn, T. A. (2014) Macrophage activation and polarization: nomenclature and experimental guidelines. Immunity 41, 14–20.
12. Xue, J., Schmidt, S. V., Sander, J., Draffehn, A., Krebs, W., Quester, I., De Nardo, D., Gohel, T. D., Emde, M., Schmidleithner, L., Ganesan, H., Nino-Castro, A., Mallmann, M. R., Labzin, L., Theis, H., Kraut, M., Beyer, M., Latz, E., Freeman, T. C., Ulas, T., Schultze, J. L. (2014) Transcriptome-based network analysis reveals a spectrum model of human macrophage activation. Immunity 40, 274–288.
13. Van Ginderachter, J. A., Movahedi, K., Hassanzadeh Ghassabeh, G., Meerschaut, S., Beschin, A., Raes, G., De Baetselier, P. (2006) Classical and alternative activation of mononuclear phagocytes: picking the best of both worlds for tumor promotion. Immunobiology 211, 487–501.
14. Kzhyshkowska, J., Gratchev, A., Martens, J. H., Pervushina, O., Mamidi, S., Johansson, S., Schledzewski, K., Hansen, B., He, X., Tang, J., Nakayama, K., Goerdt, S. (2004) Stabilin-1 localizes to endosomes and the trans-Golgi network in human macrophages and interacts with GGA adaptors. J. Leukoc. Biol. 76, 1151–1161.
15. Martinez-Pomares, L., Reid, D. M., Brown, G. D., Taylor, P. R., Stillion, R. J., Linehan, S. A., Zamze, S., Gordon, S., Wong, S. Y. (2003) Analysis of mannose receptor regulation by IL-4, IL-10, and proteolytic processing using novel monoclonal antibodies. J. Leukoc. Biol. 73, 604–613.
16. Schutyser, E., Richmond, A., Van Damme, J. (2005) Involvement of CC chemokine ligand 18 (CCL18) in normal and pathological processes. J. Leukoc. Biol. 78, 14–26.
17. Arango Duque, G., Descoteaux, A. (2014) Macrophage cytokines: involvement in immunity and infectious diseases. Front. Immunol. 5, 491.
18. Wynn, T. A. (2008) Cellular and molecular mechanisms of fibrosis. J. Pathol. 214, 199–210.
19. Akdis, M., Burgler, S., Crameri, R., Eiwegger, T., Fujita, H., Gomez, E., Klunker, S., Meyer, N., O’Mahony, L., Palomares, O., Rhyner, C., Ouaked, N., Schaffartzik, A., Van De Veen, W., Zeller, S., Zimmermann, M., Akdis, C. A. (2011) Interleukins, from 1 to 37, and interferon-gamma: receptors, functions, and roles in diseases. J. Allergy Clin. Immunol. 127, 701–721.e1–70.
20. Bradley, J. R. (2008) TNF-mediated inflammatory disease. J. Pathol. 214, 149–160.
21. Kasraie, S., Werfel, T. (2013) Role of macrophages in the pathogenesis of atopic dermatitis. Mediators Inflamm. 2013, 942375.
22. Tanaka, T., Kishimoto, T. (2014) The biology and medical implications of interleukin-6. Cancer Immunol. Res. 2, 288–294.
23. Turner, M. D., Nedjai, B., Hurst, T., Pennington, D. J. (2014) Cytokines and chemokines: at the crossroads of cell signalling and inflammatory disease. Biochim. Biophys. Acta 1843, 2563–2582.
24. Tsicopoulos, A., Chang, Y., Ait Yahia, S., de Nadai, P., Chenivesse, C. (2013) Role of CCL18 in asthma and lung immunity. Clin. Exp. Allergy 43, 716–722.
25. Gangadharan, B., Hoeve, M. A., Allen, J. E., Ebrahimi, B., Rhind, S. M., Dutia, B. M., Nash, A. A. (2008) Murine gammaherpesvirus-induced fibrosis is associated with the development of alternatively activated macrophages. J. Leukoc. Biol. 84, 50–58.
26. Migliaccio, C. T., Buford, M. C., Jessop, F., Holian, A. (2008) The IL- 4Ralpha pathway in macrophages and its potential role in silica-induced pulmonary fibrosis. J. Leukoc. Biol. 83, 630–639.
27. Wynn, T. A., Barron, L. (2010) Macrophages: master regulators of inflammation and fibrosis. Semin. Liver Dis. 30, 245–257.
28. Murray, P. J., Wynn, T. A. (2011) Obstacles and opportunities for understanding macrophage polarization. J. Leukoc. Biol. 89, 557–563.
29. Hannahan, J. P., Eleazer, P. D. (2008) Comparison of success of implants versus endodontically treated teeth. J. Endod. 34, 1302–1305.
30. Sharkey, P. F., Lichstein, P. M., Shen, C., Tokarski, A. T., Parvizi, J. (2014) Why are total knee arthroplasties failing today—has anything changed after 10 years? J. Arthroplasty 29, 1774–1778.
31. Ulrich, S. D., Seyler, T. M., Bennett, D., Delanois, R. E., Saleh, K. J., Thongtrangan, I., Kuskowski, M., Cheng, E. Y., Sharkey, P. F., Parvizi, J., Stiehl, J. B., Mont, M. A. (2008) Total hip arthroplasties: what are the reasons for revision? Int. Orthop. 32, 597–604.
32. Mok, J. M., Cloyd, J. M., Bradford, D. S., Hu, S. S., Deviren, V., Smith, J. A., Tay, B., Berven, S. H. (2009) Reoperation after primary fusion for adult spinal deformity: rate, reason, and timing. Spine 34, 832–839.
33. Drews, T., Dandel, M., Krabatsch, T., Potapov, E., Stepanenko, A., Hennig, E., Lehmkuhl, H. B., Pasic, M., Weng, Y., Hetzer, R. (2011) Long-term mechanical circulatory support in 198 patients: largest singlecenter experience worldwide. ASAIO J. 57, 9–16.
34. Landgraeber, S., Jäger, M., Jacobs, J. J., Hallab, N. J. (2014) The pathology of orthopedic implant failure is mediated by innate immune system cytokines. Mediators Inflamm. 2014, 185150.
35. Beckmann, N. A., Mueller, S., Gondan, M., Jaeger, S., Reiner, T., Bitsch, R. G. (2015) Treatment of severe bone defects during revision total knee arthroplasty with structural allografts and porous metal conesa systematic review. J. Arthroplasty 30, 249–253.
36. Abu-Amer, Y., Darwech, I., Clohisy, J. C. (2007) Aseptic loosening of total joint replacements: mechanisms underlying osteolysis and potential therapies. Arthritis Res. Ther. 9 (Suppl 1), S6.
37. Purdue, P. E., Koulouvaris, P., Potter, H. G., Nestor, B. J., Sculco, T. P. (2007) The cellular and molecular biology of periprosthetic osteolysis. Clin. Orthop. Relat. Res. 454, 251–261.
38. Revell, P. A. (2008) The combined role of wear particles, macrophages and lymphocytes in the loosening of total joint prostheses. J. R. Soc. Interface 5, 1263–1278.
39. Mori, G., D’Amelio, P., Faccio, R., Brunetti, G. (2013) The interplay between the bone and the immune system. Clin. Dev. Immunol. 2013, 720504.
40. Wu, A. C., Raggatt, L. J., Alexander, K. A., Pettit, A. R. (2013) Unraveling macrophage contributions to bone repair. Bonekey Rep. 2, 373.
41. O’Neill, S. C., Queally, J. M., Devitt, B. M., Doran, P. P., O’Byrne, J. M. (2013) The role of osteoblasts in peri-prosthetic osteolysis. Bone Joint J. 95-B, 1022–1026.
42. Steinbeck, M. J., Jablonowski, L. J., Parvizi, J., Freeman, T. A. (2014) The role of oxidative stress in aseptic loosening of total hip arthroplasties. J. Arthroplasty 29, 843–849.
43. Nakashima, Y., Sun, D. H., Trindade, M. C., Chun, L. E., Song, Y., Goodman, S. B., Schurman, D. J., Maloney, W. J., Smith, R. L. (1999) Induction of macrophage C-C chemokine expression by titanium alloy and bone cement particles. J. Bone Joint Surg. Br. 81, 155–162.
44. Rakshit, D. S., Ly, K., Sengupta, T. K., Nestor, B. J., Sculco, T. P., Ivashkiv, L. B., Purdue, P. E. (2006) Wear debris inhibition of anti-osteoclastogenic signaling by interleukin-6 and interferon-gamma. Mechanistic insights and implications for periprosthetic osteolysis. J. Bone Joint Surg. Am. 88, 788–799.
45. Koreny, T., Tunyogi-Csapó, M., Gál, I., Vermes, C., Jacobs, J. J., Glant, T. T. (2006) The role of fibroblasts and fibroblast-derived factors in periprosthetic osteolysis. Arthritis Rheum. 54, 3221–3232.
46. Lochner, K., Fritsche, A., Jonitz, A., Hansmann, D., Mueller, P., Mueller- Hilke, B., Bader, R. (2011) The potential role of human osteoblasts for periprosthetic osteolysis following exposure to wear particles. Int. J. Mol. Med. 28, 1055–1063.
47. Pioletti, D. P., Kottelat, A. (2004) The influence of wear particles in the expression of osteoclastogenesis factors by osteoblasts. Biomaterials 25, 5803–5808.
48. Anderson, J. M., Rodriguez, A., Chang, D. T. (2008) Foreign body reaction to biomaterials. Semin. Immunol. 20, 86–100.
49. Arciola, C. R., Campoccia, D., Speziale, P., Montanaro, L., Costerton, J. W. (2012) Biofilm formation in Staphylococcus implant infections. A review of molecular mechanisms and implications for biofilm-resistant materials. Biomaterials 33, 5967–5982.
50. Grotenhuis, N., Bayon, Y., Lange, J. F., Van Osch, G. J., Bastiaansen- Jenniskens, Y. M. (2013) A culture model to analyze the acute biomaterial-dependent reaction of human primary macrophages. Biochem. Biophys. Res. Commun. 433, 115–120.
51. Grotenhuis, N., Vd Toom, H. F., Kops, N., Bayon, Y., Deerenberg, E. B., Mulder, I. M., van Osch, G. J., Lange, J. F., Bastiaansen-Jenniskens, Y. M. (2014) In vitro model to study the biomaterial-dependent reaction of macrophages in an inflammatory environment. Br. J. Surg. 101, 983–992.
52. Suzuki, R., Muyco, J., McKittrick, J., Frangos, J. A. (2003) Reactive oxygen species inhibited by titanium oxide coatings. J. Biomed. Mater. Res. A66, 396–402.
53. Purdue, P. E., Koulouvaris, P., Nestor, B. J., Sculco, T. P. (2006) The central role of wear debris in periprosthetic osteolysis. HSS J. 2, 102–113.
54. Yagil-Kelmer, E., Kazmier, P., Rahaman, M. N., Bal, B. S., Tessman, R. K., Estes, D. M. (2004) Comparison of the response of primary human blood monocytes and the U937 human monocytic cell line to two different sizes of alumina ceramic particles. J. Orthop. Res. 22, 832–838.
55. Goodman, S. B., Gibon, E., Pajarinen, J., Lin, T. H., Keeney, M., Ren, P. G., Nich, C., Yao, Z., Egashira, K., Yang, F., Konttinen, Y. T. (2014) Novel biological strategies for treatment of wear particle-induced periprosthetic osteolysis of orthopaedic implants for joint replacement. J. R. Soc. Interface 11, 20130962.
56. Pajarinen, J., Kouri, V. P., Jämsen, E., Li, T. F., Mandelin, J., Konttinen, Y. T. (2013) The response of macrophages to titanium particles is determined by macrophage polarization. Acta Biomater. 9, 9229–9240.
57. Sussman, E. M., Halpin, M. C., Muster, J., Moon, R. T., Ratner, B. D. (2014) Porous implants modulate healing and induce shifts in local macrophage polarization in the foreign body reaction. Ann. Biomed. Eng. 42, 1508–1516.
58. Zaveri, T. D., Lewis, J. S., Dolgova, N. V., Clare-Salzler, M. J., Keselowsky, B. G. (2014) Integrin-directed modulation of macrophage responses to biomaterials. Biomaterials 35, 3504–3515.
59. Love, R. J., Jones, K. S. (2013) The recognition of biomaterials: pattern recognition of medical polymers and their adsorbed biomolecules. J. Biomed. Mater. Res. A101, 2740–2752.
60. Nakashima, Y., Sun, D. H., Trindade, M. C., Maloney, W. J., Goodman, S. B., Schurman, D. J., Smith, R. L. (1999) Signaling pathways for tumor necrosis factor-alpha and interleukin-6 expression in human macrophages exposed to titanium-alloy particulate debris in vitro. J. Bone Joint Surg. Am. 81, 603–615.
61. Pearl, J. I., Ma, T., Irani, A. R., Huang, Z., Robinson, W. H., Smith, R. L., Goodman, S. B. (2011) Role of the Toll-like receptor pathway in the recognition of orthopedic implant wear-debris particles. Biomaterials 32, 5535–5542.
62. Rogers, T. H., Babensee, J. E. (2010) Altered adherent leukocyte profile on biomaterials in Toll-like receptor 4 deficient mice. Biomaterials 31, 594–601.
63. Lin, T. H., Tamaki, Y., Pajarinen, J., Waters, H. A., Woo, D. K., Yao, Z., Goodman, S. B. (2014) Chronic inflammation in biomaterial-induced periprosthetic osteolysis: NF-kB as a therapeutic target. Acta Biomater. 10, 1–10.
64. Arredouani, M. S., Yang, Z., Imrich, A., Ning, Y., Qin, G., Kobzik, L. (2006) The macrophage scavenger receptor SR-AI/II and lung defense against pneumococci and particles. Am. J. Respir. Cell Mol. Biol. 35, 474–478.
65. Wolf, M. T., Dearth, C. L., Ranallo, C. A., LoPresti, S. T., Carey, L. E., Daly, K. A., Brown, B. N., Badylak, S. F. (2014) Macrophage polarization in response to ECM coated polypropylene mesh. Biomaterials 35, 6838–6849.
66. Rostam, H. M., Singh, S., Vrana, N. E., Alexander, M. R., Ghaemmaghami, A. M. (2015) Impact of surface chemistry and topography on the function of antigen presenting cells. Biomater. Sci. 3, 424–441.
67. Zhang, L., Cao, Z., Bai, T., Carr, L., Ella-Menye, J. R., Irvin, C., Ratner, B. D., Jiang, S. (2013) Zwitterionic hydrogels implanted in mice resist the foreign-body reaction. Nat. Biotechnol. 31, 553–556.
68. Rao, A. J., Nich, C., Dhulipala, L. S., Gibon, E., Valladares, R., Zwingenberger, S., Smith, R. L., Goodman, S. B. (2013) Local effect of IL-4 delivery on polyethylene particle induced osteolysis in the murine calvarium. J. Biomed. Mater. Res. A101, 1926–1934.
69. Paul, N. E., Skazik, C., Harwardt, M., Bartneck, M., Denecke, B., Klee, D., Salber, J., Zwadlo-Klarwasser, G. (2008) Topographical control of human macrophages by a regularly microstructured polyvinylidene fluoride surface. Biomaterials 29, 4056–4064.
70. Chen, S., Jones, J. A., Xu, Y., Low, H. Y., Anderson, J. M., Leong, K. W. (2010) Characterization of topographical effects on macrophage behavior in a foreign body response model. Biomaterials 31, 3479–3491.
71. Nilsson, B., Korsgren, O., Lambris, J. D., Ekdahl, K. N. (2010) Can cells and biomaterials in therapeutic medicine be shielded from innate immune recognition? Trends Immunol. 31, 32–38.
72. Morais, J. M., Papadimitrakopoulos, F., Burgess, D. J. (2010) Biomaterials/tissue interactions: possible solutions to overcome foreign body response. AAPS J. 12, 188–196.
73. Acharya, A. P., Dolgova, N. V., Clare-Salzler, M. J., Keselowsky, B. G. (2008) Adhesive substrate-modulation of adaptive immune responses. Biomaterials 29, 4736–4750.
74. Kim, Y. K., Que, R., Wang, S. W., Liu, W. F. (2014) Modification of biomaterials with a self-protein inhibits the macrophage response. Adv. Healthc. Mater. 3, 989–994.
75. Slee, J. B., Christian, A. J., Levy, R. J., Stachelek, S. J. (2014) Addressing the inflammatory response to clinically relevant polymers by manipulating the host response using ITIM domain-containing receptors. Polymers (Basel) 6, 2526–2551.
76. Park, J., Babensee, J. E. (2012) Differential functional effects of biomaterials on dendritic cell maturation. Acta Biomater. 8, 3606–3617.
77. Wisniewski, N., Reichert, M. (2000) Methods for reducing biosensor membrane biofouling. Colloids Surf. B Biointerfaces 18, 197–219.
78. Busscher, H. J., van der Mei, H. C., Subbiahdoss, G., Jutte, P. C., van den Dungen, J. J. A. M., Zaat, S. A. J., Schultz, M. J., Grainger, D. W. (2012) Biomaterial-associated infection: locating the finish line in the race for the surface. Sci. Transl. Med. 4, 153rv10.
79. Statz, A. R., Meagher, R. J., Barron, A. E., Messersmith, P. B. (2005) New peptidomimetic polymers for antifouling surfaces. J. Am. Chem. Soc. 127, 7972–7973.
80. Peppas, N. A., Huang, Y., Torres-Lugo, M., Ward, J. H., Zhang, J. (2000) Physicochemical foundations and structural design of hydrogels in medicine and biology. Annu. Rev. Biomed. Eng. 2, 9–29.
81. Welzel, P. B., Friedrichs, J., Grimmer, M., Vogler, S., Freudenberg, U., Werner, C. (2014) Cryogel micromechanics unraveled by atomic force microscopy-based nanoindentation. Adv. Healthc. Mater. 3, 1849–1853.
82. Garcia-Alonso, D., Parco, M., Stokes, J., Looney, L. (2012) Low-energy plasma spray (LEPS) deposition of hydroxyapatite/poly-e-caprolactone biocomposite coatings. J. Therm. Spray Techn. 21, 132–143.
83. Damanik, F. F., Rothuizen, T. C., van Blitterswijk, C., Rotmans, J. I., Moroni, L. (2014) Towards an in vitro model mimicking the foreign body response: tailoring the surface properties of biomaterials to modulate extracellular matrix. Sci. Rep. 4, 6325.
84. Müller, S., Koenig, G., Charpiot, A., Debry, C., Voegel, J.-C., Lavalle, P., Vautier, D. (2008) VEGF-functionalized polyelectrolyte multilayers as proangiogenic prosthetic coatings. Adv. Funct. Mater. 18, 1767–1775.
85. Vrana, N. E., Erdemli, O., Francius, G., Fahs, A., Rabineau, M., Debry, C., Tezcaner, A., Keskin, D., Lavalle, P. (2014) Double entrapment of growth factors by nanoparticles loaded into polyelectrolyte multilayer films. J. Mater. Chem. B2, 999–1008.
86. Schultz, P., Vautier, D., Richert, L., Jessel, N., Haikel, Y., Schaaf, P., Voegel, J.-C., Ogier, J., Debry, C. (2005) Polyelectrolyte multilayers functionalized by a synthetic analogue of an anti-inflammatory peptide, a-MSH, for coating a tracheal prosthesis. Biomaterials 26, 2621–2630.
87. Ma, M., Liu, W. F., Hill, P. S., Bratlie, K. M., Siegwart, D. J., Chin, J., Park, M., Guerreiro, J., Anderson, D. G. (2011) Development of cationic polymer coatings to regulate foreign-body responses. Adv. Mater. 23, H189–H194.
88. Yoshida, M., Langer, R., Lendlein, A., Lahann, J. (2006) From advanced biomedical coatings to multi‐functionalized biomaterials. J. Macromol. Sci. Polymer Rev. 46, 347–375.
89. Gao, G., Lange, D., Hilpert, K., Kindrachuk, J., Zou, Y., Cheng, J. T., Kazemzadeh-Narbat, M., Yu, K., Wang, R., Straus, S. K., Brooks, D. E., Chew, B. H., Hancock, R. E., Kizhakkedathu, J. N. (2011) The biocompatibility and biofilm resistance of implant coatings based on hydrophilic polymer brushes conjugated with antimicrobial peptides. Biomaterials 32, 3899–3909.
90. Subbiahdoss, G., Kuijer, R., Grijpma, D. W., van der Mei, H. C., Busscher, H. J. (2009) Microbial biofilm growth vs. tissue integration: “the race for the surface” experimentally studied. Acta Biomater. 5, 1399–1404.
91. Paital, S. R., Dahotre, N. B. (2009) Calcium phosphate coatings for bioimplant applications: Materials, performance factors, and methodologies. Mater. Sci. Eng. R-Rep. 66, 1–70.
92. Stankevich, K. S., Gudima, A., Filimonov, V. D., Klüter, H., Mamontova, E. M., Tverdokhlebov, S. I., Kzhyshkowska, J. (2015) Surface modification of biomaterials based on high-molecular polylactic acid and their effect on inflammatory reactions of primary human monocyte-derived macrophages: perspective for personalized therapy. Mater. Sci. Eng. C51, 117–126.