The biocompatibility and biofilm resistance of implant coatings based on hydrophilic polymer brushes conjugated with antimicrobial peptides

Biomaterials

Volumn 32, Issue 16, 2011, Pages 3899-3909

  Gao, Guangzheng ^a   Lange, Dirk ^a   Hilpert, Kai ^b   Kindrachuk, Jason ^a   Zou, Yuquan ^a   Cheng, John T J ^a   Kazemzadeh Narbat, Mehdi ^a   Yu, Kai ^a   Wang, Rizhi ^a   Straus, Suzana K ^a   Brooks, Donald E ^a   Chew, Ben H ^a   Hancock, Robert E W ^a   Kizhakkedathu, Jayachandran N ^a  

^a UNIVERSITY OF BRITISH COLUMBIA   (Canada)

^b KARLSRUHE INSTITUTE OF TECHNOLOGY   (Germany)

Author keywords

Antimicrobial coatings; Antimicrobial peptides; Biofilm resistance; Blood tissue toxicity; Implant associated infection; Polymer brushes

Indexed keywords

ANTIMICROBIAL COATINGS; ANTIMICROBIAL PEPTIDE; BLOOD/TISSUE TOXICITY; IMPLANT-ASSOCIATED INFECTION; POLYMER BRUSHES;

BIOCOMPATIBILITY; BIOFILMS; BIOFILTERS; BRUSHES; CONJUGATED POLYMERS; HYDROPHILICITY; MICROORGANISMS; PEPTIDES; POLYMERS; TOXICITY;

PLASTIC COATINGS;

PEPTIDE DERIVATIVE; POLYMER;

ANIMAL CELL; ANTIMICROBIAL ACTIVITY; ARTICLE; BACTERIAL COLONIZATION; BIOCOMPATIBILITY; BIOFILM; COMPLEMENT ACTIVATION; CONJUGATION; CONTROLLED STUDY; COVALENT BOND; FEMALE; HYDROPHILICITY; IMPLANT; IN VITRO STUDY; IN VIVO STUDY; INFECTION RESISTANCE; MATERIAL COATING; NONHUMAN; OSTEOBLAST; PRIORITY JOURNAL; RAT; THROMBOCYTE ACTIVATION; THROMBOCYTE ADHESION;

ANIMALS; ANTI-BACTERIAL AGENTS; BIOFILMS; CELL LINE, TUMOR; CIRCULAR DICHROISM; COATED MATERIALS, BIOCOMPATIBLE; FEMALE; HUMANS; MICROSCOPY, ATOMIC FORCE; PEPTIDES; PLATELET ACTIVATION; POLYMERS; PROSTHESES AND IMPLANTS; RATS; RATS, SPRAGUE-DAWLEY;

BACTERIA (MICROORGANISMS);

EID: 79953029837     PISSN: 01429612     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.biomaterials.2011.02.013     Document Type: Article

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