Local effect of IL-4 delivery on polyethylene particle induced osteolysis in the murine calvarium

Journal of Biomedical Materials Research - Part A

Volumn 101 A, Issue 7, 2013, Pages 1926-1934

  Rao, Allison J ^a   Nich, Christophe ^a   Dhulipala, Lakshmi S ^a   Gibon, Emmanuel ^a   Valladares, Roberto ^a   Zwingenberger, Stefan ^a   Smith, R Lane ^a   Goodman, Stuart B ^a  

^a STANFORD UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

interleukin 4; macrophage polarization; murine calvarium; osteolysis; polyethylene particles

Indexed keywords

HISTOMORPHOMETRIC ANALYSIS; INTERLEUKIN-4; ISOLATION AND IDENTIFICATION; MURINE CALVARIUM; OSTEOLYSIS; PERIPROSTHETIC OSTEOLYSIS; POLYETHYLENE PARTICLES; TOTAL JOINT REPLACEMENT;

BONE; CHEMICAL ACTIVATION; MACROPHAGES; POLARIZATION; POLYETHYLENES; TISSUE;

COMPUTERIZED TOMOGRAPHY;

INTERLEUKIN 1 RECEPTOR ACCESSORY PROTEIN; POLYETHYLENE; RECOMBINANT INTERLEUKIN 4; SODIUM CHLORIDE; TUMOR NECROSIS FACTOR ALPHA;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BONE MASS; CALVARIA; CELL CULTURE; CONTROLLED STUDY; CYTOKINE PRODUCTION; DRUG DELIVERY SYSTEM; MACROPHAGE; MALE; MICRO-COMPUTED TOMOGRAPHY; MORPHOMETRICS; MOUSE; NONHUMAN; OSTEOLYSIS; WESTERN BLOTTING;

ACID PHOSPHATASE; ANIMALS; BETA-N-ACETYLHEXOSAMINIDASES; BIOLOGICAL MARKERS; BLOTTING, WESTERN; BONE REMODELING; CYTOKINES; DRUG DELIVERY SYSTEMS; ENZYME-LINKED IMMUNOSORBENT ASSAY; INTERLEUKIN-4; ISOENZYMES; LECTINS; MICE; MICE, INBRED C57BL; NITRIC OXIDE SYNTHASE TYPE II; OSTEOCLASTS; OSTEOLYSIS; POLYETHYLENES; RANK LIGAND; SKULL; TOMOGRAPHY, X-RAY COMPUTED; TUMOR NECROSIS FACTOR-ALPHA;

EID: 84878292921     PISSN: 15493296     EISSN: 15524965     Source Type: Journal    
DOI: 10.1002/jbm.a.34486     Document Type: Article

References (54)

1. Koulouvaris P, Ly K, Ivashkiv LB, Bostrom MP, Nestor BJ, Sculco TP, Purdue PE,. Expression profiling reveals alternative macrophage activation and impaired osteogenesis in periprosthetic osteolysis. J Orthop Res 2008; 26: 106-116.
2. Ma T, and, Goodman, SB,. Biological effects of wear debris from joint arthroplasties In:, Wnek GE, Gary LB, editors. Encyclopedia of Biomaterials and Biomedical Engineering. London: Informa Healthcare; 2008.
3. Purdue PE, Koulouvaris P, Nestor BJ, Sculco TP,. The central role of wear debris in periprosthetic osteolysis. Hss J 2006; 2: 102-113.
4. Chiu R, Ma T, Smith RL, Goodman SB,. Ultrahigh molecular weight polyethylene wear debris inhibits osteoprogenitor proliferation and differentiation in vitro. J Biomed Mater Res A 2009; 89: 242-247.
5. Chiu R, Smith KE, Ma GK, Ma T, Smith RL, Goodman SB,. Polymethylmethacrylate particles impair osteoprogenitor viability and expression of osteogenic transcription factors Runx2, osterix, and Dlx5. J Orthop Res 2010; 28: 571-577.
6. Wooley PH, Schwarz EM,. Aseptic loosening. Gene Ther 2004; 11: 402-407.
7. Marshall A, Ries MD, Paprosky W,. How prevalent are implant wear and osteolysis, and how has the scope of osteolysis changed since 2000? J Am Acad Orthop Surg 2008; 16 (Suppl 1): S1-S6.
8. Goodman S,. Wear particulate and osteolysis. Orthop Clin North Am 2005; 36: 41-8, vi.
9. Goodman SB,. Wear particles, periprosthetic osteolysis and the immune system. Biomaterials 2007; 28: 5044-5048.
10. Tuan RS, Lee FY, Y TK, Wilkinson JM, Smith RL,. What are the local and systemic biologic reactions and mediators to wear debris, and what host factors determine or modulate the biologic response to wear particles? J Am Acad Orthop Surg 2008; 16 (Suppl 1): S42-S48.
11. Ingham E, Fisher J,. The role of macrophages in osteolysis of total joint replacement. Biomaterials 2005; 26: 1271-1286.
12. Ho VW, Sly LM,. Derivation and characterization of murine alternatively activated (M2) macrophages. Methods Mol Biol 2009; 531: 173-185.
13. Cheng J, Liu J, Shi Z, Xu D, Luo S, Siegal GP, Feng X, Wei S,. Interleukin-4 inhibits RANKL-induced NFATc1 expression via STAT6: A novel mechanism mediating its blockade of osteoclastogenesis. J Cell Biochem 2011; 112: 3385-3392.
14. Xu J, Wu HF, Ang ES, Yip K, Woloszyn M, Zheng MH, Tan RX,. NF-kappaB modulators in osteolytic bone diseases. Cytokine Growth Factor Rev 2009; 20: 7-17.
15. Granchi D, Amato I, Battistelli L, Ciapetti G, Pagani S, Avnet S, Baldini N, Giunti A,. Molecular basis of osteoclastogenesis induced by osteoblasts exposed to wear particles. Biomaterials 2005; 26: 2371-2379.
16. Goater JJ, O'Keefe RJ, Rosier RN, Puzas JE, Schwarz EM,. Efficacy of ex vivo OPG gene therapy in preventing wear debris induced osteolysis. J Orthop Res 2002; 20: 169-173.
17. Brown BN, Valentin JE, Stewart-Akers AM, McCabe GP, Badylak SF,. Macrophage phenotype and remodeling outcomes in response to biologic scaffolds with and without a cellular component. Biomaterials 2009; 30: 1482-1491.
18. Mantovani A, Sica A, Sozzani S, Allavena P, Vecchi A, Locati M,. The chemokine system in diverse forms of macrophage activation and polarization. Trends Immunol 2004; 25: 677-686.
19. Brown BN, Ratner BD, Goodman SB, Amar S, Badylak SF,. Macrophage polarization: An opportunity for improved outcomes in biomaterials and regenerative medicine. Biomaterials 2012; 33: 3792-3802.
20. Purdue PE,. Alternative macrophage activation in periprosthetic osteolysis. Autoimmunity 2008; 41: 212-217.
21. Sica A, Mantovani A,. Macrophage plasticity and polarization: in vivo veritas. J Clin Invest 2010; 122: 787-795.
22. Sharda DR, Yu S, Ray M, Squadrito ML, De Palma M, Wynn TA, Morris SM Jr, Hankey PA,. Regulation of macrophage arginase expression and tumor growth by the ron receptor tyrosine kinase. J Immunol 187: 2181-2192.
23. Kawanishi N, Yano H, Yokogawa Y, Suzuki K,. Exercise training inhibits inflammation in adipose tissue via both suppression of macrophage infiltration and acceleration of phenotypic switching from M1 to M2 macrophages in high-fat-diet-induced obese mice. Exerc Immunol Rev 2010; 16: 105-118.
24. Lumeng CN, Bodzin JL, Saltiel AR,. Obesity induces a phenotypic switch in adipose tissue macrophage polarization. J Clin Invest 2007; 117: 175-184.
25. Raes G, Noel W, Beschin A, Brys L, de Baetselier P, Hassanzadeh GH,. FIZZ1 and Ym as tools to discriminate between differentially activated macrophages. Dev Immunol 2002; 9: 151-159.
26. Jensen TO, Schmidt H, Moller HJ, Hoyer M, Maniecki MB, Sjoegren P, Christensen IJ, Steiniche T,. Macrophage markers in serum and tumor have prognostic impact in American Joint Committee on Cancer stage I/II melanoma. J Clin Oncol 2009; 27: 3330-3337.
27. Rao AJ, Gibon E, Ma T, Yao Z, Lane Smith R, Goodman SB,. Revision joint replacement, wear particles, and macrophage polarization. Acta Biomater 2012; 8: 2815-2823.
28. Chomarat P, Banchereau J,. An update on interleukin-4 and its receptor. Eur Cytokine Netw 1997; 8: 333-344.
29. Watanabe K, Tanaka Y, Morimoto I, Yahata K, Zeki K, Fujihira T, Yamashita U, Eto S,. Interleukin-4 as a potent inhibitor of bone resorption. Biochem Biophys Res Commun 1990; 172: 1035-1041.
30. Kasono K, Sato K, Sato Y, Tsushima T, Shizume K, Demura H,. Inhibitory effect of interleukin-4 on osteoclast-like cell formation in mouse bone marrow culture. Bone Miner 1993; 21: 179-188.
31. Yamada A, Takami M, Kawawa T, Yasuhara R, Zhao B, Mochizuki A, Miyamoto Y, Eto T, Yasuda H, Nakamichi Y, et al. Interleukin-4 inhibition of osteoclast differentiation is stronger than that of interleukin-13 and they are equivalent for induction of osteoprotegerin production from osteoblasts. Immunology 2007; 120: 573-579.
32. Bizzarri C, Shioi A, Teitelbaum SL, Ohara J, Harwalkar VA, Erdmann JM, Lacey DL, Civitelli R,. Interleukin-4 inhibits bone resorption and acutely increases cytosolic Ca2+ in murine osteoclasts. J Biol Chem 1994; 269: 13817-13824.
33. Miossec P, Briolay J, Dechanet J, Wijdenes J, Martinez-Valdez H, Banchereau J,. Inhibition of the production of proinflammatory cytokines and immunoglobulins by interleukin-4 in an ex vivo model of rheumatoid synovitis. Arthritis Rheum 1992; 35: 874-883.
34. Riancho JA, Zarrabeitia MT, Mundy GR, Yoneda T, Gonzalez-Macias J,. Effects of interleukin-4 on the formation of macrophages and osteoclast-like cells. J Bone Miner Res 1993; 8: 1337-1344.
35. Miossec P, Chomarat P, Dechanet J, Moreau JF, Roux JP, Delmas P, Banchereau J,. Interleukin-4 inhibits bone resorption through an effect on osteoclasts and proinflammatory cytokines in an ex vivo model of bone resorption in rheumatoid arthritis. Arthritis Rheum 1994; 37: 1715-1722.
36. Lubberts E, Joosten LA, Chabaud M, van Den Bersselaar L, Oppers B, Coenen-De Roo CJ, Richards CD, Miossec P, van Den Berg WB,. IL-4 gene therapy for collagen arthritis suppresses synovial IL-17 and osteoprotegerin ligand and prevents bone erosion. J Clin Invest 2000; 105: 1697-1710.
37. Wang Y, Zhou R, Wu NN, Mou YQ, Li RD, Deng ZL,. [Interleukin-4 and osteoprotegerin suppress polyethylene wear debris-induced osteolysis in a murine air pouch model]. Nan Fang Yi Ke Da Xue Xue Bao 2011; 31: 1709-1713.
38. Lange C, Schuler T, Blankenstein T,. Interleukin 4 gene-defective mice reconstituted with wild-type bone marrow fail to produce normal immunoglobulin E levels. J Exp Med 1998; 187: 1487-1493.
39. Goldhill J, Morris SC, Maliszewski C, Urban JF Jr, Funk CD, Finkelman FD, Shea-Donohue T,. Interleukin-4 modulates cholinergic neural control of mouse small intestinal longitudinal muscle. Am J Physiol 1997; 272 (Part 1): G1135-G1140.
40. Pearl JI, Ma T, Irani AR, Huang Z, Robinson WH, Smith RL, Goodman SB,. Role of the Toll-like receptor pathway in the recognition of orthopedic implant wear-debris particles. Biomaterials 2011; 32: 5535-5542.
41. Gibon E, Yao Z, Rao AJ, Zwingenberger S, Batke B, Valladares R, Smith RL, Biswal S, Gambhir SS, Goodman SB,. Effect of a CCR1 receptor antagonist on systemic trafficking of MSCs and polyethylene particle-associated bone loss. Biomaterials 2012; 33: 3632-3638.
42. Nich C, Langlois J, Marchadier A, Vidal C, Cohen-Solal M, Petite H, Hamadouche M,. Oestrogen deficiency modulates particle-induced osteolysis. Arthritis Res Ther 2011; 13: R100.
43. da Silva RP, Gordon S,. Phagocytosis stimulates alternative glycosylation of macrosialin (mouse CD68), a macrophage-specific endosomal protein. Biochem J 1999; 338 (Part 3): 687-694.
44. Langlois J, Hamadouche M,. New animal models of wear-particle osteolysis. Int Orthop 2011; 35: 245-251.
45. Schwarz EM, Benz EB, Lu AP, Goater JJ, Mollano AV, Rosier RN, Puzas JE, Okeefe RJ,. Quantitative small-animal surrogate to evaluate drug efficacy in preventing wear debris-induced osteolysis. J Orthop Res 2000; 18: 849-855.
46. von Knoch F, Heckelei A, Wedemeyer C, Saxler G, Hilken G, Brankamp J, Sterner T, Landgraeber S, Henschke F, Loer F, et al. Suppression of polyethylene particle-induced osteolysis by exogenous osteoprotegerin. J Biomed Mater Res A 2005; 75: 288-294.
47. Greenfield EM, Tatro JM, Smith MV, Schnaser EA, Wu D,. PI3Kgamma deletion reduces variability in the in vivo osteolytic response induced by orthopaedic wear particles. J Orthop Res 2011; 29: 1649-1653.
48. Bozic KJ, Kurtz S, Lau E, Ong K, Chiu V, Vail TP, Rubash HE, Berry DJ,. The epidemiology of bearing surface usage in total hip arthroplasty in the United States. J Bone Joint Surg Am 2009; 91: 1614-1620.
49. Bozic KJ, Ong K, Lau E, Kurtz SM, Vail TP, Rubash HE, Berry DJ,. Risk of complication and revision total hip arthroplasty among Medicare patients with different bearing surfaces. Clin Orthop Relat Res 2010; 468: 2357-2362.
50. Gibon E, Ma T, Ren PG, Fritton K, Biswal S, Yao Z, Smith L, Goodman SB,. Selective inhibition of the MCP-1-CCR2 ligand-receptor axis decreases systemic trafficking of macrophages in the presence of UHMWPE particles. J Orthop Res 2012: 30: 547-553.
51. Beatty GL, Chiorean EG, Fishman MP, Saboury B, Teitelbaum UR, Sun W, Huhn RD, Song W, Li D, Sharp LL, et al. CD40 agonists alter tumor stroma and show efficacy against pancreatic carcinoma in mice and humans. Science 2011; 331: 1612-1616.
52. Stienstra R, Duval C, Keshtkar S, van der Laak J, Kersten S, Muller M,. Peroxisome proliferator-activated receptor gamma activation promotes infiltration of alternatively activated macrophages into adipose tissue. J Biol Chem 2008; 283: 22620-22627.
53. Lu M, Sarruf DA, Talukdar S, Sharma S, Li P, Bandyopadhyay G, Nalbandian S, Fan W, Gayen JR, Mahata SK, et al. Brain PPAR-gamma promotes obesity and is required for the insulin-sensitizing effect of thiazolidinediones. Nat Med 2011; 17: 618-622.
54. Charo IF,. Macrophage polarization and insulin resistance: PPARgamma in control. Cell Metab 2007; 6: 96-98.