MicroRNA-33-dependent regulation of macrophage metabolism directs immune cell polarization in atherosclerosis

Journal of Clinical Investigation

Volumn 125, Issue 12, 2015, Pages 4334-4348

  Ouimet, Mireille ^a   Ediriweera, Hasini N ^a   Mahesh Gundra, U ^a   Sheedy, Frederick J ^a   Ramkhelawon, Bhama ^a   Hutchison, Susan B ^a   Rinehold, Kaitlyn ^a   Van Solingen, Coen ^a   Fullerton, Morgan D ^b   Cecchini, Katharine ^c   Rayner, Katey J ^b   Steinberg, Gregory R ^d   Zamore, Phillip D ^c   Fisher, Edward A ^a   Loke, Png ^a   Moore, Kathryn J ^a  

^a NEW YORK UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b UNIVERSITY OF OTTAWA   (Canada)

^c UNIVERSITY OF MASSACHUSETTS MEDICAL SCHOOL   (United States)

^d MCMASTER UNIVERSITY   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

ALDEHYDE DEHYDROGENASE; ALDEHYDE DEHYDROGENASE FAMILY 1 SUBFAMILY A2; CHOLESTEROL; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE KINASE; MICRORNA; MICRORNA 33; RETINAL DEHYDROGENASE; TRANSCRIPTION FACTOR FOXP3; UNCLASSIFIED DRUG; ALDH1A2 PROTEIN, MOUSE; FORKHEAD TRANSCRIPTION FACTOR; FOXP3 PROTEIN, MOUSE; MIRN33 MICRORNA, MOUSE;

ADAPTIVE IMMUNITY; AEROBIC GLYCOLYSIS; AEROBIC METABOLISM; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; ATHEROSCLEROSIS; CD4+ T LYMPHOCYTE; CELL METABOLISM; CELL POLARITY; CHOLESTEROL TRANSPORT; CONTROLLED STUDY; ENZYME ACTIVITY; GENE DELETION; GLYCOLYSIS; IMMUNOCOMPETENT CELL; IN VITRO STUDY; INFLAMMATORY CELL; INNATE IMMUNITY; MACROPHAGE; METABOLIC REGULATION; MITOCHONDRIAL RESPIRATION; MOUSE; NONHUMAN; OXIDATIVE PHOSPHORYLATION; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN INDUCTION; REGULATORY T LYMPHOCYTE; ANIMAL; ATHEROSCLEROTIC PLAQUE; GENE EXPRESSION REGULATION; GENETICS; IMMUNOLOGY; KNOCKOUT MOUSE; OXYGEN CONSUMPTION; PATHOLOGY; PERITONEUM MACROPHAGE;

ALDEHYDE DEHYDROGENASE; AMP-ACTIVATED PROTEIN KINASES; ANIMALS; ATHEROSCLEROSIS; FORKHEAD TRANSCRIPTION FACTORS; GENE EXPRESSION REGULATION; GLYCOLYSIS; MACROPHAGES, PERITONEAL; MICE; MICE, KNOCKOUT; MICRORNAS; OXYGEN CONSUMPTION; PLAQUE, ATHEROSCLEROTIC; T-LYMPHOCYTES, REGULATORY;

EID: 84948799436     PISSN: 00219738     EISSN: 15588238     Source Type: Journal    
DOI: 10.1172/JCI81676     Document Type: Article

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