Toward the replacement of animal experiments through the bioinformatics-driven analysis of 'omics' data from human cell cultures

ATLA Alternatives to Laboratory Animals

Volumn 43, Issue 5, 2015, Pages 325-332

  Grafström, Roland C ^a   Nymark, Penny ^a   Hongisto, Vesa ^b   Spjuth, Ola ^a,c   Ceder, Rebecca ^a   Willighagen, Egon ^d   Hardy, Barry ^e   Kaski, Samuel ^f   Kohonen, Pekka ^a  

^a KAROLINSKA INSTITUTE   (Sweden)

^b Misvik Biology Corporation   (Finland)

^c UPPSALA UNIVERSITY   (Sweden)

^d MAASTRICHT UNIVERSITY   (Netherlands)

^e Douglas Connect GmbH   (Switzerland)

^f AALTO UNIVERSITY   (Finland)

Author keywords

Adverse outcome pathway; Alternative methods; Benchmark dose; Bioinformatics; Databases; In silico; Systems toxicology; Toxicogenomics

Indexed keywords

ANIMAL EXPERIMENT; ARTICLE; AWARDS AND PRIZES; BIOINFORMATICS; COMPREHENSION; COMPUTER MODEL; CONCEPTUAL FRAMEWORK; HIGH THROUGHPUT SCREENING; HUMAN; HUMAN CELL; HUMAN CELL CULTURE; IN VITRO STUDY; INFORMATION PROCESSING; META ANALYSIS (TOPIC); NONHUMAN; PRIORITY JOURNAL; ANIMAL TESTING ALTERNATIVE; BIOLOGY; RISK ASSESSMENT; TOXICOGENETICS;

ANIMAL TESTING ALTERNATIVES; COMPUTATIONAL BIOLOGY; HUMANS; RISK ASSESSMENT; TOXICOGENETICS;

EID: 84948756624     PISSN: 02611929     EISSN: 26323559     Source Type: Journal    
DOI: 10.1177/026119291504300506     Document Type: Article

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