-
1
-
-
0013769940
-
Oxidative phosphorylation. Biochemical effects and properties of trialkyltins
-
Aldridge WN, Street BW. 1964. Oxidative phosphorylation. Biochemical effects and properties of trialkyltins. Biochem J 91(2):287-297.
-
(1964)
Biochem J
, vol.91
, Issue.2
, pp. 287-297
-
-
Aldridge, W.N.1
Street, B.W.2
-
2
-
-
84884229460
-
Systematic study of mitochondrial toxicity of environmental chemicals using quantitative high throughput screening
-
Attene-Ramos MS, Huang R, Sakamuru S, Witt KL, Beeson GC, Shou L, et al. 2013a. Systematic study of mitochondrial toxicity of environmental chemicals using quantitative high throughput screening. Chem Res Toxicol 26(9):1323-1332.
-
(2013)
Chem Res Toxicol
, vol.26
, Issue.9
, pp. 1323-1332
-
-
Attene-Ramos, M.S.1
Huang, R.2
Sakamuru, S.3
Witt, K.L.4
Beeson, G.C.5
Shou, L.6
-
3
-
-
84881124332
-
The Tox21 robotic platform for the assessment of environmental chemicals—from vision to reality
-
Attene-Ramos MS, Miller N, Huang R, Michael S, Itkin M, Kavlock RJ, et al. 2013b. The Tox21 robotic platform for the assessment of environmental chemicals—from vision to reality. Drug Discov Today 18(15-16):716-723.
-
(2013)
Drug Discov Today
, vol.18
, Issue.15-16
, pp. 716-723
-
-
Attene-Ramos, M.S.1
Miller, N.2
Huang, R.3
Michael, S.4
Itkin, M.5
Kavlock, R.J.6
-
4
-
-
0022515187
-
Organization of citric-acid cycle enzymes into a multienzyme cluster
-
Barnes SJ, Weitzman PDJ. 1986. Organization of citric-acid cycle enzymes into a multienzyme cluster. FEBS Lett 201(2):267-270.
-
(1986)
FEBS Lett
, vol.201
, Issue.2
, pp. 267-270
-
-
Barnes, S.J.1
Weitzman, P.2
-
5
-
-
0028047262
-
Dynamics of mitochondria in living cells: Shape changes, dislocations, fusion, and fission of mitochondria
-
Bereiter-Hahn J, Vöth M. 1994. Dynamics of mitochondria in living cells: shape changes, dislocations, fusion, and fission of mitochondria. Microsc Res Tech 27(3):198-219.
-
(1994)
Microsc Res Tech
, vol.27
, Issue.3
, pp. 198-219
-
-
Bereiter-Hahn, J.1
Vöth, M.2
-
6
-
-
0023185218
-
Uncoupling effect of fungal hydroxyanthraquinones on mitochondrial oxidative-phosphorylation
-
Betina V, Kuzela S. 1987. Uncoupling effect of fungal hydroxyanthraquinones on mitochondrial oxidative-phosphorylation. Chem Biol Interact 62(2):179-189.
-
(1987)
Chem Biol Interact
, vol.62
, Issue.2
, pp. 179-189
-
-
Betina, V.1
Kuzela, S.2
-
7
-
-
0343471523
-
A proposal for a new mechanism of interaction of trialkyltin (TAT) compounds with mitochondria
-
Bragadin M, Marton D. 1997. A proposal for a new mechanism of interaction of trialkyltin (TAT) compounds with mitochondria. J Inorg Biochem 68(1):75-78.
-
(1997)
J Inorg Biochem
, vol.68
, Issue.1
, pp. 75-78
-
-
Bragadin, M.1
Marton, D.2
-
8
-
-
0033802875
-
Chronic exposure to bryostatin-1 increases the radio sensitivity of U937 leukaemia cells ectopically expressing Bcl-2 through a non-apoptotic mechanism
-
Cartee L, Davis C, Lin PS, Grant S. 2000. Chronic exposure to bryostatin-1 increases the radio sensitivity of U937 leukaemia cells ectopically expressing Bcl-2 through a non-apoptotic mechanism. Int J Radiat Biol 76(10):1323-1333.
-
(2000)
Int J Radiat Biol
, vol.76
, Issue.10
, pp. 1323-1333
-
-
Cartee, L.1
Davis, C.2
Lin, P.S.3
Grant, S.4
-
9
-
-
0027499070
-
The use of ATP bioluminescence as a measure of cell-proliferation and cytotoxicity
-
Crouch SPM, Kozlowski R, Slater KJ, Fletcher J. 1993. the use of ATP bioluminescence as a measure of cell-proliferation and cytotoxicity. J Immunol Methods 160(1):81-88.
-
(1993)
J Immunol Methods
, vol.160
, Issue.1
, pp. 81-88
-
-
Crouch, S.1
Kozlowski, R.2
Slater, K.J.3
Fletcher, J.4
-
10
-
-
0032930655
-
Introduction to mitochondrial function and genomics
-
Dykens JA, Davis RE, Moos WH. 1999. Introduction to mitochondrial function and genomics. Drug Dev Res 46(1):2-13.
-
(1999)
Drug Dev Res
, vol.46
, Issue.1
, pp. 2-13
-
-
Dykens, J.A.1
Davis, R.E.2
Moos, W.H.3
-
11
-
-
0015935031
-
Transport of ornithine and citrulline across the mitochondrial membrane
-
Gamble JG, Lehninger AL. 1973. Transport of ornithine and citrulline across the mitochondrial membrane. J Biol Chem 248(2):610-618.
-
(1973)
J Biol Chem
, vol.248
, Issue.2
, pp. 610-618
-
-
Gamble, J.G.1
Lehninger, A.L.2
-
12
-
-
79961042769
-
Chemical genomics profiling of environmental chemical modulation of human nuclear receptors
-
Huang R, Xia M, Cho MH, Sakamuru S, Shinn P, Houck KA, et al. 2011. Chemical genomics profiling of environmental chemical modulation of human nuclear receptors. Environ Health Perspect 119:1142-1148; doi:10.1289/ehp.1002952.
-
(2011)
Environ Health Perspect
, vol.119
, pp. 1142-1148
-
-
Huang, R.1
Xia, M.2
Cho, M.H.3
Sakamuru, S.4
Shinn, P.5
Houck, K.A.6
-
13
-
-
33746789921
-
Quantitative high-throughput screening: A titration-based approach that effi-ciently identifies biological activities in large chemical libraries
-
Inglese J, Auld DS, Jadhav A, Johnson RL, Simeonov A, Yasgar A, et al. 2006. Quantitative high-throughput screening: a titration-based approach that effi-ciently identifies biological activities in large chemical libraries. Proc Natl Acad Sci USA 103(31):11473-11478.
-
(2006)
Proc Natl Acad Sci USA
, vol.103
, Issue.31
, pp. 11473-11478
-
-
Inglese, J.1
Auld, D.S.2
Jadhav, A.3
Johnson, R.L.4
Simeonov, A.5
Yasgar, A.6
-
14
-
-
62749084516
-
Toxicity testing in the 21st century: Implications for human health risk assessment
-
Kavlock RJ, Austin CP, Tice RR. 2009. Toxicity testing in the 21st century: implications for human health risk assessment. Risk Anal 29(4):485-487.
-
(2009)
Risk Anal
, vol.29
, Issue.4
, pp. 485-487
-
-
Kavlock, R.J.1
Austin, C.P.2
Tice, R.R.3
-
15
-
-
33746588228
-
Self-organizing neural projections
-
Kohonen T. 2006. Self-organizing neural projections. Neural Netw 19(6-7):723-733.
-
(2006)
Neural Netw
, vol.19
, Issue.6-7
, pp. 723-733
-
-
Kohonen, T.1
-
16
-
-
0033376516
-
Mitochondrial effects of triarylmethane dyes
-
Kowaltowski AJ, Turin J, Indig GL, Vercesi AE. 1999. Mitochondrial effects of triarylmethane dyes. J Bioenerg Biomembr 31(6):581-590.
-
(1999)
J Bioenerg Biomembr
, vol.31
, Issue.6
, pp. 581-590
-
-
Kowaltowski, A.J.1
Turin, J.2
Indig, G.L.3
Vercesi, A.E.4
-
17
-
-
0020411223
-
Steroidogenic electron-transport in adrenal-cortex mitochondria
-
Lambeth JD, Seybert DW, Lancaster JR, Salerno JC, Kamin H. 1982. Steroidogenic electron-transport in adrenal-cortex mitochondria. Mol Cell Biochem 45(1):13-31.
-
(1982)
Mol Cell Biochem
, vol.45
, Issue.1
, pp. 13-31
-
-
Lambeth, J.D.1
Seybert, D.W.2
Lancaster, J.R.3
Salerno, J.C.4
Kamin, H.5
-
18
-
-
0036775488
-
Role of mitochondrial inner membrane permeabilization in necrotic cell death, apoptosis, and autophagy
-
Lemasters JJ, Qian T, He L, Kim JS, Elmore SP, Cascio WE, et al. 2002. Role of mitochondrial inner membrane permeabilization in necrotic cell death, apoptosis, and autophagy. Antioxid Redox Signal 4(5):769-781.
-
(2002)
Antioxid Redox Signal
, vol.4
, Issue.5
, pp. 769-781
-
-
Lemasters, J.J.1
Qian, T.2
He, L.3
Kim, J.S.4
Elmore, S.P.5
Cascio, W.E.6
-
19
-
-
0032504657
-
Role of mitochondria in oxidative stress and ageing
-
Lenaz G. 1998. Role of mitochondria in oxidative stress and ageing. Biochim Biophys Acta 1366(1-2):53-67.
-
(1998)
Biochim Biophys Acta
, vol.1366
, Issue.1-2
, pp. 53-67
-
-
Lenaz, G.1
-
20
-
-
0034960785
-
Mitochondrial dysfunction in cardiac disease: Ischemia—reperfusion, aging, and heart failure
-
Lesnefsky EJ, Moghaddas S, Tandler B, Kerner J, Hoppel CL. 2001. Mitochondrial dysfunction in cardiac disease: ischemia—reperfusion, aging, and heart failure. J Mol Cell Cardiol 33(6):1065-1089.
-
(2001)
J Mol Cell Cardiol
, vol.33
, Issue.6
, pp. 1065-1089
-
-
Lesnefsky, E.J.1
Moghaddas, S.2
Tandler, B.3
Kerner, J.4
Hoppel, C.L.5
-
21
-
-
0032746009
-
The essential role of mitochondria in the biogenesis of cellular iron-sulfur proteins
-
Lill R, Diekert K, Kaut A, Lange H, Pelzer W, Prohl C, et al. 1999. The essential role of mitochondria in the biogenesis of cellular iron-sulfur proteins. Biol Chem 380(10):1157-1166.
-
(1999)
Biol Chem
, vol.380
, Issue.10
, pp. 1157-1166
-
-
Lill, R.1
Diekert, K.2
Kaut, A.3
Lange, H.4
Pelzer, W.5
Prohl, C.6
-
22
-
-
0032843270
-
Infrared spectroscopic study of bryostatin 1-induced membrane alterations in a B-CLL cell line
-
Liu KZ, Schultz CP, Johnston JB, Beck FW, Al-Katib AM, Mohammad RM, et al. 1999. Infrared spectroscopic study of bryostatin 1-induced membrane alterations in a B-CLL cell line. Leukemia 13(8):1273-1280.
-
(1999)
Leukemia
, vol.13
, Issue.8
, pp. 1273-1280
-
-
Liu, K.Z.1
Schultz, C.P.2
Johnston, J.B.3
Beck, F.W.4
Al-Katib, A.M.5
Mohammad, R.M.6
-
23
-
-
77957242874
-
Role of mitochon-drial dysfunction in cardiac glycoside toxicity
-
Liu T, Brown DA, O’Rourke B. 2010. Role of mitochon-drial dysfunction in cardiac glycoside toxicity. J Mol Cell Cardiol 49(5):728-736.
-
(2010)
J Mol Cell Cardiol
, vol.49
, Issue.5
, pp. 728-736
-
-
Liu, T.1
Brown, D.A.2
O’Rourke, B.3
-
24
-
-
33746016268
-
Mitochondria: More than just a powerhouse
-
McBride HM, Neuspiel M, Wasiak S. 2006. Mitochondria: more than just a powerhouse. Curr Biol 16(14):R551-R560.
-
(2006)
Curr Biol
, vol.16
, Issue.14
, pp. R551-R560
-
-
McBride, H.M.1
Neuspiel, M.2
Wasiak, S.3
-
25
-
-
36949083936
-
Coupling of phosphorylation to electron and hydrogen transfer by a chemi-osmotic type of mechanism
-
Mitchell P. 1961. Coupling of phosphorylation to electron and hydrogen transfer by a chemi-osmotic type of mechanism. Nature 191:144-148.
-
(1961)
Nature
, vol.191
, pp. 144-148
-
-
Mitchell, P.1
-
26
-
-
84859915614
-
Anthracyclines and mitochondria
-
Mordente A, Meucci E, Silvestrini A, Martorana GE, Giardina B. 2012. Anthracyclines and mitochondria. Adv Exp Med Biol 942:385-419.
-
(2012)
Adv Exp Med Biol
, vol.942
, pp. 385-419
-
-
Mordente, A.1
Meucci, E.2
Silvestrini, A.3
Martorana, G.E.4
Giardina, B.5
-
27
-
-
79955637356
-
Investigating mitochondrial dysfunction to increase drug safety in the pharma-ceutical industry
-
Nadanaciva S, Will Y. 2011. Investigating mitochondrial dysfunction to increase drug safety in the pharma-ceutical industry. Curr Drug Targets 12(6):774-782.
-
(2011)
Curr Drug Targets
, vol.12
, Issue.6
, pp. 774-782
-
-
Nadanaciva, S.1
Will, Y.2
-
28
-
-
0345368076
-
Mechanism of p-hydroxybenzoate ester-induced mitochondrial dysfunction and cytotoxicity in isolated rat hepato-cytes
-
Nakagawa Y, Moldeus P. 1998. Mechanism of p-hydroxybenzoate ester-induced mitochondrial dysfunction and cytotoxicity in isolated rat hepato-cytes. Biochem Pharmacol 55(11):1907-1914.
-
(1998)
Biochem Pharmacol
, vol.55
, Issue.11
, pp. 1907-1914
-
-
Nakagawa, Y.1
Moldeus, P.2
-
29
-
-
84872418997
-
The development of structure-activity relation ships for mitochondrial dysfunction: Uncoup ling of oxidative phosphorylation
-
Naven RT, Swiss R, Klug-McLeod J, Will Y, Greene N. 2013. The development of structure-activity relation ships for mitochondrial dysfunction: uncoup ling of oxidative phosphorylation. Toxicol Sci 131(1):271-278.
-
(2013)
Toxicol Sci
, vol.131
, Issue.1
, pp. 271-278
-
-
Naven, R.T.1
Swiss, R.2
Klug-McLeod, J.3
Will, Y.4
Greene, N.5
-
30
-
-
0035365868
-
Tributyltin interacts with mitochondria and induces cytochrome c release
-
Nishikimi A, Kira Y, Kasahara E, Sato EF, Kanno T, Utsumi K, et al. 2001. Tributyltin interacts with mitochondria and induces cytochrome c release. Biochem J 356(Pt 2):621-626.
-
(2001)
Biochem J
, vol.356
, pp. 621-626
-
-
Nishikimi, A.1
Kira, Y.2
Kasahara, E.3
Sato, E.F.4
Kanno, T.5
Utsumi, K.6
-
31
-
-
59149099408
-
-
NTP (National Toxicology Program), Roadmap to Achieve the NTP Vision, accessed 22 September 2014
-
NTP (National Toxicology Program). 2004. A National Toxicology Program for the 21st Century. Roadmap to Achieve the NTP Vision. Available: http://ntp.niehs.nih.gov/ntp/about_ntp/ntpvision/ ntproadmap_508.pdf [accessed 22 September 2014].
-
(2004)
A National Toxicology Program for the 21St Century
-
-
-
32
-
-
0035421320
-
Propagation of the apoptotic signal by mitochondrial waves
-
Pacher P, Hajnóczky G. 2001. Propagation of the apoptotic signal by mitochondrial waves. EMBO J 20(15):4107-4121.
-
(2001)
EMBO J
, vol.20
, Issue.15
, pp. 4107-4121
-
-
Pacher, P.1
Hajnóczky, G.2
-
33
-
-
84875263814
-
Toxicity of organotin compounds: Shared and unshared biochemical targets and mechanisms in animal cells
-
Pagliarani A, Nesci S, Ventrella V. 2013. Toxicity of organotin compounds: shared and unshared biochemical targets and mechanisms in animal cells. Toxicol In Vitro 27(2):978-990.
-
(2013)
Toxicol in Vitro
, vol.27
, Issue.2
, pp. 978-990
-
-
Pagliarani, A.1
Nesci, S.2
Ventrella, V.3
-
34
-
-
34249671789
-
Mitochondrial dysfunction and molecular pathways of disease
-
Pieczenik SR, Neustadt J. 2007. Mitochondrial dysfunction and molecular pathways of disease. Exp Mol Pathol 83(1):84-92.
-
(2007)
Exp Mol Pathol
, vol.83
, Issue.1
, pp. 84-92
-
-
Pieczenik, S.R.1
Neustadt, J.2
-
35
-
-
84862144439
-
Application of a homogenous membrane potential assay to assess mitochondrial function
-
Sakamuru S, Li X, Attene-Ramos MS, Huang R, Lu J, Shou L, et al. 2012. Application of a homogenous membrane potential assay to assess mitochondrial function. Physiol Genomics 44(9):495-503.
-
(2012)
Physiol Genomics
, vol.44
, Issue.9
, pp. 495-503
-
-
Sakamuru, S.1
Li, X.2
Attene-Ramos, M.S.3
Huang, R.4
Lu, J.5
Shou, L.6
-
36
-
-
84990519181
-
Organotin compounds: Toxicology and biomedicinal applications
-
Saxena AK. 1987. Organotin compounds: toxicology and biomedicinal applications. Appl Organomet Chem 1(1):39-56.
-
(1987)
Appl Organomet Chem
, vol.1
, Issue.1
, pp. 39-56
-
-
Saxena, A.K.1
-
37
-
-
84857356559
-
Mito-conundrum unraveling environ-mental effects on mitochondria
-
Schmidt CW. 2010. Mito-conundrum unraveling environ-mental effects on mitochondria. Environ Health Perspect 118:A292-A297; doi:10.1289/ehp.118-a292.
-
(2010)
Environ Health Perspect
, vol.118
, pp. A292-A297
-
-
Schmidt, C.W.1
-
38
-
-
78649630186
-
The future of toxicity testing: A focus on in vitro methods using a quantitative high-throughput screening platform
-
Shukla SJ, Huang R, Austin CP, Xia M. 2010. The future of toxicity testing: a focus on in vitro methods using a quantitative high-throughput screening platform. Drug Discov Today 15(23-24):997-1007.
-
(2010)
Drug Discov Today
, vol.15
, Issue.23-24
, pp. 997-1007
-
-
Shukla, S.J.1
Huang, R.2
Austin, C.P.3
Xia, M.4
-
39
-
-
34250691686
-
Electron microscopy of mitochondria and cytoplasmic double membranes
-
Sjostrand FS. 1953. Electron microscopy of mitochondria and cytoplasmic double membranes. Nature 171(4340):30-32.
-
(1953)
Nature
, vol.171
, Issue.4340
, pp. 30-32
-
-
Sjostrand, F.S.1
-
40
-
-
0004765667
-
Inhibitory action of tri alkyltin compounds on oxidative phosphorylation in mitochondria
-
Sone N, Hagihara B. 1964. Inhibitory action of tri alkyltin compounds on oxidative phosphorylation in mitochondria. J Biochem 56:151-156.
-
(1964)
J Biochem
, vol.56
, pp. 151-156
-
-
Sone, N.1
Hagihara, B.2
-
41
-
-
43149124006
-
Toward a class-independent quantitative structure— activity relationship model for uncou-plers of oxidative phosphorylation
-
Spycher S, Smejtek P, Netzeva TI, Escher BI. 2008. Toward a class-independent quantitative structure— activity relationship model for uncou-plers of oxidative phosphorylation. Chem Res Toxicol 21(4):911-927.
-
(2008)
Chem Res Toxicol
, vol.21
, Issue.4
, pp. 911-927
-
-
Spycher, S.1
Smejtek, P.2
Netzeva, T.I.3
Escher, B.I.4
-
42
-
-
84879599189
-
Improving the human hazard characterization of chemicals: A Tox21 update
-
Tice RR, Austin CP, Kavlock RJ, Bucher JR. 2013. Improving the human hazard characterization of chemicals: a Tox21 update. Environ Health Perspect 121:756-765; doi:10.1289/ehp.1205784.
-
(2013)
Environ Health Perspect
, vol.121
, pp. 756-765
-
-
Tice, R.R.1
Austin, C.P.2
Kavlock, R.J.3
Bucher, J.R.4
-
43
-
-
0036739108
-
Effects of troglitazone on HepG2 viability and mitochondrial function
-
Tirmenstein MA, Hu CX, Gales TL, Maleeff BE, Narayanan PK, Kurali E, et al. 2002. Effects of troglitazone on HepG2 viability and mitochondrial function. Toxicol Sci 69(1):131-138.
-
(2002)
Toxicol Sci
, vol.69
, Issue.1
, pp. 131-138
-
-
Tirmenstein, M.A.1
Hu, C.X.2
Gales, T.L.3
Maleeff, B.E.4
Narayanan, P.K.5
Kurali, E.6
-
44
-
-
0032856994
-
Induction of apopto sis by apigenin and related flavonoids through cytochrome c release and activation of caspase-9 and caspase-3 in leukaemia HL-60 cells
-
Wang IK, Lin-Shiau SY, Lin JK. 1999. Induction of apopto sis by apigenin and related flavonoids through cytochrome c release and activation of caspase-9 and caspase-3 in leukaemia HL-60 cells. Eur J Cancer 35(10):1517-1525.
-
(1999)
Eur J Cancer
, vol.35
, Issue.10
, pp. 1517-1525
-
-
Wang, I.K.1
Lin-Shiau, S.Y.2
Lin, J.K.3
-
45
-
-
0037218430
-
Bryostatin 1 and UCN-01 potentiate 1-β-d-arabinofuranosyl cytosineinduced apoptosis in human myeloid leukemia cells through disparate mechanisms
-
Wang S, Wang Z, Grant S. 2003. Bryostatin 1 and UCN-01 potentiate 1-β-d-arabinofuranosyl cytosineinduced apoptosis in human myeloid leukemia cells through disparate mechanisms. Mol Pharmacol 63(1):232-242.
-
(2003)
Mol Pharmacol
, vol.63
, Issue.1
, pp. 232-242
-
-
Wang, S.1
Wang, Z.2
Grant, S.3
|