Repeated injections of IL-2 break renal allograft tolerance induced via mixed hematopoietic chimerism in monkeys

American Journal of Transplantation

Volumn 15, Issue 12, 2015, Pages 3055-3066

  Yamada, Y ^a   Nadazdin, O ^a   Boskovic, S ^a   Lee, S ^a   Zorn, E ^a   Smith, R N ^b   Colvin, R B ^b   Madsen, J C ^a   Cosimi, A B ^a   Kawai, T ^a   Benichou, G ^a  

^a HARVARD MEDICAL SCHOOL   (United States)

^b MASSACHUSETTS GENERAL HOSPITAL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIINFLAMMATORY AGENT; CD8 ANTIGEN; CREATININE; GAMMA INTERFERON; RECOMBINANT INTERLEUKIN 2; TRANSCRIPTION FACTOR FOXP3; INTERLEUKIN 2;

ACUTE GRAFT REJECTION; ALLOIMMUNITY; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIINFLAMMATORY ACTIVITY; ARTICLE; BLEEDING; BONE MARROW TRANSPLANTATION; CAPILLARITIS; CD25+ T LYMPHOCYTE; CD4+ T LYMPHOCYTE; CELL AGGREGATION; CELL EXPANSION; CELL INFILTRATION; CELL STIMULATION; CONCENTRATION (PARAMETERS); CONCENTRATION RESPONSE; CONTROLLED STUDY; CREATININE BLOOD LEVEL; DRUG WITHDRAWAL; EXPERIMENTAL MONKEY; GRAFT SURVIVAL; HEMATOPOIETIC SYSTEM; HISTOCOMPATIBILITY; IMMUNOSUPPRESSIVE TREATMENT; IN VITRO STUDY; IN VIVO STUDY; INFLAMMATORY CELL; KIDNEY ALLOGRAFT; KIDNEY ALLOGRAFT REJECTION; KIDNEY BIOPSY; LEUKOCYTE COUNT; LOW DRUG DOSE; LYMPHOCYTE COUNT; LYMPHOCYTE DEPLETION; LYMPHOCYTE PROLIFERATION; LYMPHOID ORGAN; MACACA FASCICULARIS; MEMORY T LYMPHOCYTE; MONONUCLEAR CELL; NATURAL KILLER CELL; NEPHRITIS; NONHUMAN; PERIPHERAL LYMPHOCYTE; POSTOPERATIVE COMPLICATION; PREOPERATIVE PERIOD; PRIORITY JOURNAL; PROTEIN SECRETION; REGULATORY T LYMPHOCYTE; RENOVASCULAR DISEASE; T CELL DEPLETION; T LYMPHOCYTE ACTIVATION; TRANSPLANTATION TOLERANCE; UPREGULATION; ALLOTRANSPLANTATION; ANIMAL; CHIMERA; GLOMERULUS FILTRATION RATE; GRAFT REJECTION; IMMUNOLOGY; KIDNEY FAILURE, CHRONIC; KIDNEY FUNCTION TEST; KIDNEY TRANSPLANTATION; MOUSE; RISK FACTOR; SUBCUTANEOUS DRUG ADMINISTRATION; TRANSPLANTATION CONDITIONING;

ANIMALS; BONE MARROW TRANSPLANTATION; CHIMERISM; GLOMERULAR FILTRATION RATE; GRAFT REJECTION; GRAFT SURVIVAL; INJECTIONS, SUBCUTANEOUS; INTERLEUKIN-2; KIDNEY FAILURE, CHRONIC; KIDNEY FUNCTION TESTS; KIDNEY TRANSPLANTATION; MACACA FASCICULARIS; MICE; POSTOPERATIVE COMPLICATIONS; RISK FACTORS; TRANSPLANTATION CHIMERA; TRANSPLANTATION CONDITIONING; TRANSPLANTATION TOLERANCE; TRANSPLANTATION, HOMOLOGOUS;

EID: 84948712286     PISSN: 16006135     EISSN: 16006143     Source Type: Journal    
DOI: 10.1111/ajt.13382     Document Type: Article

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