-
1
-
-
84859416933
-
Regulatory T cells: Mechanisms of differentiation and function
-
Josefowicz SZ, Lu LF, Rudensky AY (2012) Regulatory T cells: Mechanisms of differentiation and function. Annu Rev Immunol 30:531-564.
-
(2012)
Annu Rev Immunol
, vol.30
, pp. 531-564
-
-
Josefowicz, S.Z.1
Lu, L.F.2
Rudensky, A.Y.3
-
2
-
-
67649170980
-
Foxp3+ regulatory T cells: Differentiation, specification, subphenotypes
-
Feuerer M, Hill JA, Mathis D, Benoist C (2009) Foxp3+ regulatory T cells: Differentiation, specification, subphenotypes. Nat Immunol 10(7):689-695.
-
(2009)
Nat Immunol
, vol.10
, Issue.7
, pp. 689-695
-
-
Feuerer, M.1
Hill, J.A.2
Mathis, D.3
Benoist, C.4
-
3
-
-
84948652334
-
-
eds Mathis D, Rudensky A (Cold Spring Harbor Press, Cold Spring Harbor, NY)
-
Benoist C, Mathis D (2013) Immune Tolerance, eds Mathis D, Rudensky A (Cold Spring Harbor Press, Cold Spring Harbor, NY), pp 31-44.
-
(2013)
Immune Tolerance
, pp. 31-44
-
-
Benoist, C.1
Mathis, D.2
-
4
-
-
84930821357
-
Regulatory T cell identity: Formation and maintenance
-
Li X, Zheng Y (2015) Regulatory T cell identity: Formation and maintenance. Trends Immunol 36(6):344-353.
-
(2015)
Trends Immunol
, vol.36
, Issue.6
, pp. 344-353
-
-
Li, X.1
Zheng, Y.2
-
5
-
-
84899659467
-
FOXP3 and scurfy: How it all began
-
Ramsdell F, Ziegler SF (2014) FOXP3 and scurfy: How it all began. Nat Rev Immunol 14(5):343-349.
-
(2014)
Nat Rev Immunol
, vol.14
, Issue.5
, pp. 343-349
-
-
Ramsdell, F.1
Ziegler, S.F.2
-
6
-
-
84886694563
-
Regulatory T cells in nonlymphoid tissues
-
Burzyn D, Benoist C, Mathis D (2013) Regulatory T cells in nonlymphoid tissues. Nat Immunol 14(10):1007-1013.
-
(2013)
Nat Immunol
, vol.14
, Issue.10
, pp. 1007-1013
-
-
Burzyn, D.1
Benoist, C.2
Mathis, D.3
-
7
-
-
33645102841
-
An intersection between the self-reactive regulatory and nonregulatory T cell receptor repertoires
-
Hsieh CS, Zheng Y, Liang Y, Fontenot JD, Rudensky AY (2006) An intersection between the self-reactive regulatory and nonregulatory T cell receptor repertoires. Nat Immunol 7(4):401-410.
-
(2006)
Nat Immunol
, vol.7
, Issue.4
, pp. 401-410
-
-
Hsieh, C.S.1
Zheng, Y.2
Liang, Y.3
Fontenot, J.D.4
Rudensky, A.Y.5
-
8
-
-
33747099523
-
Origin and T cell receptor diversity of Foxp3+CD4+CD25+ T cells
-
Pacholczyk R, Ignatowicz H, Kraj P, Ignatowicz L (2006) Origin and T cell receptor diversity of Foxp3+CD4+CD25+ T cells. Immunity 25(2):249-259.
-
(2006)
Immunity
, vol.25
, Issue.2
, pp. 249-259
-
-
Pacholczyk, R.1
Ignatowicz, H.2
Kraj, P.3
Ignatowicz, L.4
-
9
-
-
34249814016
-
Adaptation of TCR repertoires to self-peptides in regulatory and nonregulatory CD4+ T cells
-
Wong J, et al. (2007) Adaptation of TCR repertoires to self-peptides in regulatory and nonregulatory CD4+ T cells. J Immunol 178(11):7032-7041.
-
(2007)
J Immunol
, vol.178
, Issue.11
, pp. 7032-7041
-
-
Wong, J.1
-
10
-
-
1642326161
-
MHC class II-independent CD25+ CD4+ CD8alpha beta+ alpha beta T cells attenuate CD4+ T cell-induced transfer colitis
-
Krajina T, Leithäuser F, Reimann J (2004) MHC class II-independent CD25+ CD4+ CD8alpha beta+ alpha beta T cells attenuate CD4+ T cell-induced transfer colitis. Eur J Immunol 34(3):705-714.
-
(2004)
Eur J Immunol
, vol.34
, Issue.3
, pp. 705-714
-
-
Krajina, T.1
Leithäuser, F.2
Reimann, J.3
-
11
-
-
0035320679
-
Thymic selection of CD4+CD25+ regulatory T cells induced by an agonist self-peptide
-
Jordan MS, et al. (2001) Thymic selection of CD4+CD25+ regulatory T cells induced by an agonist self-peptide. Nat Immunol 2(4):301-306.
-
(2001)
Nat Immunol
, vol.2
, Issue.4
, pp. 301-306
-
-
Jordan, M.S.1
-
12
-
-
9244244736
-
Number of T reg cells that differentiate does not increase upon encounter of agonist ligand on thymic epithelial cells
-
van Santen HM, Benoist C, Mathis D (2004) Number of T reg cells that differentiate does not increase upon encounter of agonist ligand on thymic epithelial cells. J Exp Med 200(10):1221-1230.
-
(2004)
J Exp Med
, vol.200
, Issue.10
, pp. 1221-1230
-
-
Van Santen, H.M.1
Benoist, C.2
Mathis, D.3
-
13
-
-
79958251745
-
T cell receptor signal strength in Treg and iNKT cell development demonstrated by a novel fluorescent reporter mouse
-
Moran AE, et al. (2011) T cell receptor signal strength in Treg and iNKT cell development demonstrated by a novel fluorescent reporter mouse. J Exp Med 208(6):1279-1289.
-
(2011)
J Exp Med
, vol.208
, Issue.6
, pp. 1279-1289
-
-
Moran, A.E.1
-
14
-
-
68949105350
-
Impact of the TCR signal on regulatory T cell homeostasis, function, and trafficking
-
Kim JK, et al. (2009) Impact of the TCR signal on regulatory T cell homeostasis, function, and trafficking. PLoS One 4(8):e6580.
-
(2009)
PLoS One
, vol.4
, Issue.8
-
-
Kim, J.K.1
-
15
-
-
84912113033
-
Continuous T cell receptor signals maintain a functional regulatory T cell pool
-
Vahl JC, et al. (2014) Continuous T cell receptor signals maintain a functional regulatory T cell pool. Immunity 41(5):722-736.
-
(2014)
Immunity
, vol.41
, Issue.5
, pp. 722-736
-
-
Vahl, J.C.1
-
16
-
-
84908123494
-
Continuous requirement for the TCR in regulatory T cell function
-
Levine AG, Arvey A, Jin W, Rudensky AY (2014) Continuous requirement for the TCR in regulatory T cell function. Nat Immunol 15(11):1070-1078.
-
(2014)
Nat Immunol
, vol.15
, Issue.11
, pp. 1070-1078
-
-
Levine, A.G.1
Arvey, A.2
Jin, W.3
Rudensky, A.Y.4
-
17
-
-
0031647622
-
Immunologic self-tolerance maintained by CD25+CD4+ naturally anergic and suppressive T cells: Induction of autoimmune disease by breaking their anergic/suppressive state
-
Takahashi T, et al. (1998) Immunologic self-tolerance maintained by CD25+CD4+ naturally anergic and suppressive T cells: Induction of autoimmune disease by breaking their anergic/suppressive state. Int Immunol 10(12):1969-1980.
-
(1998)
Int Immunol
, vol.10
, Issue.12
, pp. 1969-1980
-
-
Takahashi, T.1
-
18
-
-
77951158406
-
Protein kinase C-theta mediates negative feedback on regulatory T cell function
-
Zanin-Zhorov A, et al. (2010) Protein kinase C-theta mediates negative feedback on regulatory T cell function. Science 328(5976):372-376.
-
(2010)
Science
, vol.328
, Issue.5976
, pp. 372-376
-
-
Zanin-Zhorov, A.1
-
19
-
-
84889254459
-
The ζ isoform of diacylglycerol kinase plays a predominant role in regulatory T cell development and TCR-mediated ras signaling
-
Joshi RP, et al. (2013) The ζ isoform of diacylglycerol kinase plays a predominant role in regulatory T cell development and TCR-mediated ras signaling. Sci Signal 6(303):ra102.
-
(2013)
Sci Signal
, vol.6
, Issue.303
, pp. ra102
-
-
Joshi, R.P.1
-
20
-
-
63849121372
-
SHIP limits immunoregulatory capacity in the T-cell compartment
-
Collazo MM, et al. (2009) SHIP limits immunoregulatory capacity in the T-cell compartment. Blood 113(13):2934-2944.
-
(2009)
Blood
, vol.113
, Issue.13
, pp. 2934-2944
-
-
Collazo, M.M.1
-
21
-
-
84863133195
-
Scaffold protein Disc large homolog 1 is required for Tcell receptor-induced activation of regulatory T-cell function
-
Zanin-Zhorov A, et al. (2012) Scaffold protein Disc large homolog 1 is required for Tcell receptor-induced activation of regulatory T-cell function. Proc Natl Acad Sci USA 109(5):1625-1630.
-
(2012)
Proc Natl Acad Sci USA
, vol.109
, Issue.5
, pp. 1625-1630
-
-
Zanin-Zhorov, A.1
-
22
-
-
0036144888
-
Homeostasis and anergy of CD4(+)CD25(+) suppressor T cells in vivo
-
Gavin MA, Clarke SR, Negrou E, Gallegos A, Rudensky A (2002) Homeostasis and anergy of CD4(+)CD25(+) suppressor T cells in vivo. Nat Immunol 3(1):33-41.
-
(2002)
Nat Immunol
, vol.3
, Issue.1
, pp. 33-41
-
-
Gavin, M.A.1
Clarke, S.R.2
Negrou, E.3
Gallegos, A.4
Rudensky, A.5
-
23
-
-
27644503683
-
CD4+CD25+ regulatory T-cell lines from human cord blood have functional and molecular properties of T-cell anergy
-
Li L, et al. (2005) CD4+CD25+ regulatory T-cell lines from human cord blood have functional and molecular properties of T-cell anergy. Blood 106(9):3068-3073.
-
(2005)
Blood
, vol.106
, Issue.9
, pp. 3068-3073
-
-
Li, L.1
-
24
-
-
84914106706
-
Single-cell mass cytometry of TCR signaling: Amplification of small initial differences results in low ERK activation in NOD mice
-
Mingueneau M, et al. (2014) Single-cell mass cytometry of TCR signaling: Amplification of small initial differences results in low ERK activation in NOD mice. Proc Natl Acad Sci USA 111(46):16466-16471.
-
(2014)
Proc Natl Acad Sci USA
, vol.111
, Issue.46
, pp. 16466-16471
-
-
Mingueneau, M.1
-
25
-
-
50149099154
-
Differentiation of regulatory Foxp3+ T cells in the thymic cortex
-
Liston A, et al. (2008) Differentiation of regulatory Foxp3+ T cells in the thymic cortex. Proc Natl Acad Sci USA 105(33):11903-11908.
-
(2008)
Proc Natl Acad Sci USA
, vol.105
, Issue.33
, pp. 11903-11908
-
-
Liston, A.1
-
26
-
-
85047694553
-
Susceptible MHC alleles, not background genes, select an autoimmune T cell reactivity
-
Stratmann T, et al. (2003) Susceptible MHC alleles, not background genes, select an autoimmune T cell reactivity. J Clin Invest 112(6):902-914.
-
(2003)
J Clin Invest
, vol.112
, Issue.6
, pp. 902-914
-
-
Stratmann, T.1
-
27
-
-
0030825384
-
Differential T cell receptor-mediated signaling in naive and memory CD4 T cells
-
Farber DL, Acuto O, Bottomly K (1997) Differential T cell receptor-mediated signaling in naive and memory CD4 T cells. Eur J Immunol 27(8):2094-2101.
-
(1997)
Eur J Immunol
, vol.27
, Issue.8
, pp. 2094-2101
-
-
Farber, D.L.1
Acuto, O.2
Bottomly, K.3
-
28
-
-
10744221289
-
Developmental stage, phenotype, and migration distinguish naive- and effector/memory-like CD4+ regulatory T cells
-
Huehn J, et al. (2004) Developmental stage, phenotype, and migration distinguish naive- and effector/memory-like CD4+ regulatory T cells. J Exp Med 199(3):303-313.
-
(2004)
J Exp Med
, vol.199
, Issue.3
, pp. 303-313
-
-
Huehn, J.1
-
29
-
-
2442484053
-
Naturally arising CD4+ regulatory t cells for immunologic selftolerance and negative control of immune responses
-
Sakaguchi S (2004) Naturally arising CD4+ regulatory t cells for immunologic selftolerance and negative control of immune responses. Annu Rev Immunol 22:531-562.
-
(2004)
Annu Rev Immunol
, vol.22
, pp. 531-562
-
-
Sakaguchi, S.1
-
30
-
-
84355162741
-
Response to self antigen imprints regulatory memory in tissues
-
Rosenblum MD, et al. (2011) Response to self antigen imprints regulatory memory in tissues. Nature 480(7378):538-542.
-
(2011)
Nature
, vol.480
, Issue.7378
, pp. 538-542
-
-
Rosenblum, M.D.1
-
32
-
-
84928586624
-
Selective IL-2 responsiveness of regulatory T cells through multiple intrinsic mechanisms supports the use of low-dose IL-2 therapy in type 1 diabetes
-
Yu A, et al. (2015) Selective IL-2 responsiveness of regulatory T cells through multiple intrinsic mechanisms supports the use of low-dose IL-2 therapy in type 1 diabetes. Diabetes 64(6):2172-2183.
-
(2015)
Diabetes
, vol.64
, Issue.6
, pp. 2172-2183
-
-
Yu, A.1
-
33
-
-
79957750936
-
The immunomodulatory properties of the CD5 lymphocyte receptor in health and disease
-
Soldevila G, Raman C, Lozano F (2011) The immunomodulatory properties of the CD5 lymphocyte receptor in health and disease. Curr Opin Immunol 23(3):310-318.
-
(2011)
Curr Opin Immunol
, vol.23
, Issue.3
, pp. 310-318
-
-
Soldevila, G.1
Raman, C.2
Lozano, F.3
-
34
-
-
47149108867
-
CD5 plays an inhibitory role in the suppressive function of murine CD4(+) CD25(+) T(reg) cells
-
Dasu T, et al. (2008) CD5 plays an inhibitory role in the suppressive function of murine CD4(+) CD25(+) T(reg) cells. Immunol Lett 119(1-2):103-113.
-
(2008)
Immunol Lett
, vol.119
, Issue.1-2
, pp. 103-113
-
-
Dasu, T.1
-
35
-
-
84924988088
-
CD5 instructs extrathymic regulatory T cell development in response to self and tolerizing antigens
-
Henderson JG, Opejin A, Jones A, Gross C, Hawiger D (2015) CD5 instructs extrathymic regulatory T cell development in response to self and tolerizing antigens. Immunity 42(3):471-483.
-
(2015)
Immunity
, vol.42
, Issue.3
, pp. 471-483
-
-
Henderson, J.G.1
Opejin, A.2
Jones, A.3
Gross, C.4
Hawiger, D.5
-
36
-
-
65349119978
-
CD28 and CTLA-4 coreceptor expression and signal transduction
-
Rudd CE, Taylor A, Schneider H (2009) CD28 and CTLA-4 coreceptor expression and signal transduction. Immunol Rev 229(1):12-26.
-
(2009)
Immunol Rev
, vol.229
, Issue.1
, pp. 12-26
-
-
Rudd, C.E.1
Taylor, A.2
Schneider, H.3
-
37
-
-
82255192901
-
The emerging role of CTLA4 as a cell-extrinsic regulator of T cell responses
-
Walker LS, Sansom DM (2011) The emerging role of CTLA4 as a cell-extrinsic regulator of T cell responses. Nat Rev Immunol 11(12):852-863.
-
(2011)
Nat Rev Immunol
, vol.11
, Issue.12
, pp. 852-863
-
-
Walker, L.S.1
Sansom, D.M.2
-
38
-
-
65349118810
-
PD-1 signaling in primary T cells
-
Riley JL
-
Riley JL (2009) PD-1 signaling in primary T cells. Immunol Rev 229(1):114-125.
-
(2009)
Immunol Rev
, vol.229
, Issue.1
, pp. 114-125
-
-
-
39
-
-
84895910372
-
Targeting DUSPs in glioblastomas-Wielding a doubleedged sword?
-
Prabhakar S, et al. (2014) Targeting DUSPs in glioblastomas-Wielding a doubleedged sword? Cell Biol Int 38(2):145-153.
-
(2014)
Cell Biol Int
, vol.38
, Issue.2
, pp. 145-153
-
-
Prabhakar, S.1
-
40
-
-
43049101029
-
Dual-specificity MAP kinase phosphatases (MKPs) and cancer
-
Keyse SM (2008) Dual-specificity MAP kinase phosphatases (MKPs) and cancer. Cancer Metastasis Rev 27(2):253-261.
-
(2008)
Cancer Metastasis Rev
, vol.27
, Issue.2
, pp. 253-261
-
-
Keyse, S.M.1
-
41
-
-
84874425321
-
Unrestrained p38 MAPK activation in Dusp1/4 doublenull mice induces cardiomyopathy
-
Auger-Messier M, et al. (2013) Unrestrained p38 MAPK activation in Dusp1/4 doublenull mice induces cardiomyopathy. Circ Res 112(1):48-56.
-
(2013)
Circ Res
, vol.112
, Issue.1
, pp. 48-56
-
-
Auger-Messier, M.1
-
42
-
-
84872551703
-
Convergent and divergent effects of costimulatory molecules in conventional and regulatory CD4+ T cells
-
Wakamatsu E, Mathis D, Benoist C (2013) Convergent and divergent effects of costimulatory molecules in conventional and regulatory CD4+ T cells. Proc Natl Acad Sci USA 110(3):1023-1028.
-
(2013)
Proc Natl Acad Sci USA
, vol.110
, Issue.3
, pp. 1023-1028
-
-
Wakamatsu, E.1
Mathis, D.2
Benoist, C.3
-
43
-
-
67649138829
-
Regulatory T cells in the control of host-microorganism interactions (∗)
-
Belkaid Y, Tarbell K (2009) Regulatory T cells in the control of host-microorganism interactions (∗). Annu Rev Immunol 27:551-589.
-
(2009)
Annu Rev Immunol
, vol.27
, pp. 551-589
-
-
Belkaid, Y.1
Tarbell, K.2
-
44
-
-
84923040695
-
THEMIS: A critical TCR signal regulator for ligand discrimination
-
Gascoigne NR, Acuto O (2015) THEMIS: A critical TCR signal regulator for ligand discrimination. Curr Opin Immunol 33:86-92.
-
(2015)
Curr Opin Immunol
, vol.33
, pp. 86-92
-
-
Gascoigne, N.R.1
Acuto, O.2
-
45
-
-
80555154007
-
SOCS1 is essential for regulatory T cell functions by preventing loss of Foxp3 expression as well as IFN-gamma and IL-17A production
-
Takahashi R, et al. (2011) SOCS1 is essential for regulatory T cell functions by preventing loss of Foxp3 expression as well as IFN-gamma and IL-17A production. J Exp Med 208(10):2055-2067.
-
(2011)
J Exp Med
, vol.208
, Issue.10
, pp. 2055-2067
-
-
Takahashi, R.1
-
46
-
-
0032545452
-
Molecular basis of T cell inactivation by CTLA-4
-
Lee K-M, et al. (1998) Molecular basis of T cell inactivation by CTLA-4. Science 282(5397):2263-2266.
-
(1998)
Science
, vol.282
, Issue.5397
, pp. 2263-2266
-
-
Lee, K.-M.1
-
47
-
-
36048978911
-
Foxp3 transcription-factor-dependent and -independent regulation of the regulatory T cell transcriptional signature
-
Hill JA, et al. (2007) Foxp3 transcription-factor-dependent and -independent regulation of the regulatory T cell transcriptional signature. Immunity 27(5):786-800.
-
(2007)
Immunity
, vol.27
, Issue.5
, pp. 786-800
-
-
Hill, J.A.1
|