MiRNA-target chimeras reveal miRNA 3′-end pairing as a major determinant of Argonaute target specificity

Nature Communications

Volumn 6, Issue , 2015, Pages

  Moore, Michael J ^a   Scheel, Troels K H ^a,b,c   Luna, Joseph M ^a   Park, Christopher Y ^a,d   Fak, John J ^a   Nishiuchi, Eiko ^a   Rice, Charles M ^a   Darnell, Robert B ^a,d  

^a ROCKEFELLER UNIVERSITY   (United States)

^b Mental Health Services CPH   (Denmark)

^c UNIVERSITY OF COPENHAGEN   (Denmark)

^d NEW YORK GENOME CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ARGONAUTE PROTEIN; MICRORNA; RIBONUCLEASE; RNA LIGASE; MESSENGER RNA;

BIOCHEMICAL COMPOSITION; CHIMERA; HOST SPECIFICITY; MAMMAL; MOLECULAR ANALYSIS; PROTEIN; RNA;

ANIMAL TISSUE; ARTICLE; BASE PAIRING; CHIMERA; ESCHERICHIA COLI; FLOW CYTOMETRY; HUMAN; HUMAN CELL; MOUSE; NEOCORTEX; NONHUMAN; NORTHERN BLOTTING; PREDICTION; PROTEIN TARGETING; RNA SEQUENCE; WESTERN BLOTTING; ANIMAL; BINDING SITE; BRAIN; IMMUNOPRECIPITATION; METABOLISM; POLYACRYLAMIDE GEL ELECTROPHORESIS; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; RNA INTERFERENCE; TUMOR CELL LINE;

MAMMALIA;

ANIMALS; ARGONAUTE PROTEINS; BASE PAIRING; BINDING SITES; BLOTTING, NORTHERN; BLOTTING, WESTERN; BRAIN; CELL LINE, TUMOR; CHIMERA; ELECTROPHORESIS, POLYACRYLAMIDE GEL; FLOW CYTOMETRY; HUMANS; IMMUNOPRECIPITATION; MICE; MICRORNAS; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA INTERFERENCE; RNA, MESSENGER;

EID: 84948672434     PISSN: None     EISSN: 20411723     Source Type: Journal    
DOI: 10.1038/ncomms9864     Document Type: Article

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