The BAP1/ASXL2 histone H2A deubiquitinase complex regulates cell proliferation and is disrupted in cancer

Journal of Biological Chemistry

Volumn 290, Issue 48, 2015, Pages 28643-28663

  Daou, Salima ^a   Hammond Martel, Ian ^a   Mashtalir, Nazar ^a   Barbour, Haithem ^a   Gagnon, Jessica ^a   Iannantuono, Nicholas V G ^a   Nkwe, Nadine Sen ^a   Motorina, Alena ^a   Pak, Helen ^a   Yu, Helen ^a   Wurtele, Hugo ^a   Milot, Eric ^a   Mallette, Frédérick A ^a   Carbone, Michele ^b   Affar, El Bachir ^a  

^a UNIVERSITY OF MONTREAL   (Canada)

^b UNIVERSITY OF HAWAII CANCER CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BINS; CELL PROLIFERATION; CELLS; CYTOLOGY; DISEASES;

C-TERMINAL DOMAINS; CANCER DEVELOPMENT; CANCER-ASSOCIATED MUTATIONS; CATALYTIC DOMAINS; HYDROPHOBIC PATCH; INTRAMOLECULAR INTERACTIONS; MULTIPLE INTERACTIONS; TRANSCRIPTIONAL REGULATOR;

PROTEINS;

CELL PROTEIN; DEUBIQUITINASE; HISTONE H2A; HYDROLASE; PROTEIN ASXL1; PROTEIN ASXL2; PROTEIN BAP1; UBIQUITIN; UBIQUITIN CARBOXYL HYDROLASE; UNCLASSIFIED DRUG; ASXL1 PROTEIN, HUMAN; ASXL2 PROTEIN, HUMAN; BAP1 PROTEIN, HUMAN; HISTONE; MULTIPROTEIN COMPLEX; REPRESSOR PROTEIN; TUMOR SUPPRESSOR PROTEIN; UBIQUITIN THIOLESTERASE;

ARTICLE; CARBOXY TERMINAL SEQUENCE; CARCINOGENESIS; CELL AGING; CELL PROLIFERATION; COMPLEX FORMATION; CONTROLLED STUDY; DEUBIQUITINATION; GENE DELETION; GROWTH REGULATION; HUMAN; HUMAN CELL; HYDROPHOBICITY; LOSS OF FUNCTION MUTATION; MOLECULAR INTERACTION; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN DOMAIN; PROTEIN FUNCTION; PROTEIN MODIFICATION; PROTEIN PROTEIN INTERACTION; PROTEIN STABILITY; TRANSCRIPTION REGULATION; GENETICS; HEK293 CELL LINE; HELA CELL LINE; METABOLISM; NEOPLASM; PATHOLOGY;

CELL PROLIFERATION; HEK293 CELLS; HELA CELLS; HISTONES; HUMANS; MULTIPROTEIN COMPLEXES; NEOPLASMS; REPRESSOR PROTEINS; TUMOR SUPPRESSOR PROTEINS; UBIQUITIN THIOLESTERASE; UBIQUITIN-SPECIFIC PROTEASES;

EID: 84948455798     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M115.661553     Document Type: Article

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