Excessive TLR9 signaling contributes to the pathogenesis of spontaneous abortion through impairment of Treg cell survival by activation of Caspase 8/3

International Immunopharmacology

Volumn 29, Issue 2, 2015, Pages 285-292

  Kang, Xiaomin ^b   Zhang, Xiaoxin ^b   Liu, Zhilan ^b   Xu, Haijing ^b   Wang, Tongfei ^b   He, Liying ^b   Zhao, Aimin ^a  

^a SHANGHAI JIAO TONG UNIVERSITY SCHOOL OF MEDICINE   (China)

^b Shanghai Key Laboratory of Gynecologic Oncology   (China)

Author keywords

Caspase 3; Caspase 8; Regulatory T cells; Spontaneous abortion; Survival; Toll like receptor 9

Indexed keywords

CASPASE 3; CASPASE 8; CASPASE 9; CPG OLIGODEOXYNUCLEOTIDE; ODN 1826; ODN 2088; OLIGODEOXYNUCLEOTIDE; TOLL LIKE RECEPTOR 1; TOLL LIKE RECEPTOR 3; TOLL LIKE RECEPTOR 4; TOLL LIKE RECEPTOR 8; TOLL LIKE RECEPTOR 9; TOLL LIKE RECEPTOR AFFECTING AGENT; TOLL LIKE RECEPTOR AGONIST; UNCLASSIFIED DRUG; CASP3 PROTEIN, HUMAN; CASP8 PROTEIN, HUMAN; TLR4 PROTEIN, HUMAN; TLR9 PROTEIN, HUMAN; TLR9 PROTEIN, MOUSE; TOLL LIKE RECEPTOR;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CELL SURVIVAL; COMPARATIVE STUDY; CONTROLLED STUDY; ENZYME ACTIVITY; FEMALE; FETUS DEVELOPMENT; FETUS WASTAGE; GENE OVEREXPRESSION; HUMAN; HUMAN TISSUE; IN VITRO STUDY; IN VIVO STUDY; MALE; MOUSE; NONHUMAN; PATHOGENESIS; PREGNANCY; PRIORITY JOURNAL; REGULATORY T LYMPHOCYTE; SELECTIVE ABORTION; SIGNAL TRANSDUCTION; SPONTANEOUS ABORTION; ADULT; ANIMAL; BIOSYNTHESIS; CBA MOUSE; CELL PROLIFERATION; DBA MOUSE; ENZYME ACTIVATION; GENETICS; METABOLISM; PATHOPHYSIOLOGY;

ABORTION, SPONTANEOUS; ADULT; ANIMALS; CASPASE 3; CASPASE 8; CELL PROLIFERATION; CELL SURVIVAL; ENZYME ACTIVATION; FEMALE; HUMANS; MALE; MICE; MICE, INBRED CBA; MICE, INBRED DBA; PREGNANCY; SIGNAL TRANSDUCTION; T-LYMPHOCYTES, REGULATORY; TOLL-LIKE RECEPTOR 4; TOLL-LIKE RECEPTOR 9; TOLL-LIKE RECEPTORS;

EID: 84948431279     PISSN: 15675769     EISSN: 18781705     Source Type: Journal    
DOI: 10.1016/j.intimp.2015.11.004     Document Type: Article

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