Toll-like receptor 4 mediates intrauterine growth restriction after systemic Campylobacter rectus infection in mice

Molecular Oral Microbiology

Volumn 27, Issue 5, 2012, Pages 373-381

  Arce, R M ^a   Caron, K M ^b   Barros, S P ^a   Offenbacher, S ^a  

^a UNIVERSITY OF NORTH CAROLINA   (United States)

^b UNIVERSITY OF NORTH CAROLINA SCHOOL OF MEDICINE   (United States)

Author keywords

Animal models; Campylobacter rectus; Fetal growth restriction; Mice; Periodontitis; Preterm delivery; Toll like receptors

Indexed keywords

INTERLEUKIN 6; NEUTRALIZING ANTIBODY; TOLL LIKE RECEPTOR 4; TUMOR NECROSIS FACTOR ALPHA;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CAMPYLOBACTER RECTUS; CONTROLLED STUDY; CYTOKINE PRODUCTION; FEMALE; FETUS; FETUS WEIGHT; GENE OVEREXPRESSION; HETEROZYGOSITY; HUMAN; HUMAN CELL; IMMUNE RESPONSE; IN VITRO STUDY; IN VIVO STUDY; INFLAMMATION; INTRAUTERINE GROWTH RETARDATION; LOW BIRTH WEIGHT; MOUSE; NONHUMAN; PATHOGENESIS; PHENOTYPE; PLACENTA; PREMATURE LABOR; PRENATAL EXPOSURE; TROPHOBLAST; WILD TYPE;

ANIMALS; CAMPYLOBACTER INFECTIONS; CAMPYLOBACTER RECTUS; CELL LINE; CYTOKINES; DISEASE SUSCEPTIBILITY; FEMALE; FETAL GROWTH RETARDATION; FETAL WEIGHT; HETEROZYGOTE; HOMOZYGOTE; HUMANS; INFLAMMATION MEDIATORS; INTERLEUKIN-6; MALE; MICE; MICE, CONGENIC; MICE, INBRED BALB C; MICE, INBRED STRAINS; PHENOTYPE; PLACENTA; PREGNANCY; PREGNANCY COMPLICATIONS, INFECTIOUS; TOLL-LIKE RECEPTOR 4; TROPHOBLASTS; TUMOR NECROSIS FACTOR-ALPHA;

EID: 84866144498     PISSN: 20411006     EISSN: 20411014     Source Type: Journal    
DOI: 10.1111/j.2041-1014.2012.00651.x     Document Type: Article

References (48)

1. Abrahams, V.M. (2008) Antagonizing toll-like receptors to prevent preterm labor. Reprod Sci15: 108-109.
2. Abrahams, V.M. and Mor, G. (2005) Toll-like receptors and their role in the trophoblast. Placenta26: 540-547.
3. Abrahams, V.M., Bole-Aldo, P., Kim, Y.M. et al. (2004) Divergent trophoblast responses to bacterial products mediated by TLRs. J Immunol173: 4286-4296.
4. Adams Waldorf, K.M., Persing, D., Novy, M.J., Sadowsky, D.W. and Gravett, M.G. (2008) Pretreatment with toll-like receptor 4 antagonist inhibits lipopolysaccharide-induced preterm uterine contractility, cytokines, and prostaglandins in rhesus monkeys. Reprod Sci15: 121-127.
5. Albandar, J.M. (2002) Global risk factors and risk indicators for periodontal diseases. Periodontol 200029: 177-206.
6. Allos, B.M. (2001) Campylobacter jejuni infections: update on emerging issues and trends. Clin Infect Dis32: 1201-1206.
7. Arce, R.M., Barros, S.P., Wacker, B., Peters, B., Moss, K. and Offenbacher, S. (2009) Increased TLR4 expression in murine placentas after oral infection with periodontal pathogens. Placenta30: 156-162.
8. Arce, R.M., Diaz, P.I., Barros, S.P. et al. (2010) Characterization of the invasive and inflammatory traits of oral Campylobacter rectus in a murine model of fetoplacental growth restriction and in trophoblast cultures. J Reprod Immunol84: 145-153.
9. Beck, J.D. and Offenbacher, S. (2005) Systemic effects of periodontitis: epidemiology of periodontal disease and cardiovascular disease. J Periodontol76: 2089-2100.
10. Bobetsis, Y.A., Barros, S.P., Lin, D.M. et al. (2007) Bacterial infection promotes DNA hypermethylation. J Dent Res86: 169-174.
11. Bobetsis, Y.A., Barros, S.P., Lin, D.M., Arce, R.M. and Offenbacher, S. (2010) Altered gene expression in murine placentas in an infection-induced intrauterine growth restriction model: a microarray analysis. J Reprod Immunol85: 140-148.
12. Brikos, C. and O'Neill, L.A. (2008) Signalling of toll-like receptors. Handb Exp Pharmacol183: 21-50.
13. Elovitz, M.A. (2006) Anti-inflammatory interventions in pregnancy: now and the future. Semin Fetal Neonatal Med11: 327-332.
14. Elovitz, M.A. and Mrinalini, C. (2004) Animal models of preterm birth. Trends Endocrinol Metab15: 479-487.
15. Elovitz, M.A., Wang, Z., Chien, E.K., Rychlik, D.F. and Phillippe, M. (2003) A new model for inflammation-induced preterm birth: the role of platelet-activating factor and Toll-like receptor-4. Am J Pathol163: 2103-2111.
16. Fujihara, N., Takakura, S., Saito, T., Iinuma, Y. and Ichiyama, S. (2006) A case of perinatal sepsis by Campylobacter fetus subsp. fetus infection successfully treated with carbapenem-case report and literature review. J Infect53: e199-e202.
17. Goldenberg, R.L., Hauth, J.C. and Andrews, W.W. (2000) Intrauterine infection and preterm delivery. N Engl J Med342: 1500-1507.
18. Guerrant, R.L., Lahita, R.G., Winn, W.C. Jr and Roberts, R.B. (1978) Campylobacteriosis in man: pathogenic mechanisms and review of 91 bloodstream infections. Am J Med65: 584-592.
19. Han, Y.W., Redline, R.W., Li, M., Yin, L., Hill, G.B. and McCormick, T.S. (2004) Fusobacterium nucleatum induces premature and term stillbirths in pregnant mice: implication of oral bacteria in preterm birth. Infect Immun72: 2272-2279.
20. Han, Y.W., Shen, T., Chung, P., Buhimschi, I.A. and Buhimschi, C.S. (2009) Uncultivated bacteria as etiologic agents of intra-amniotic inflammation leading to preterm birth. J Clin Microbiol47: 38-47.
21. Holmlund, U., Cebers, G., Dahlfors, A.R. et al. (2002) Expression and regulation of the pattern recognition receptors Toll-like receptor-2 and Toll-like receptor-4 in the human placenta. Immunology107: 145-151.
22. Koga, K. and Mor, G. (2008) Expression and function of toll-like receptors at the maternal-fetal interface. Reprod Sci15: 231-242.
23. Kumazaki, K., Nakayama, M., Yanagihara, I., Suehara, N. and Wada, Y. (2004) Immunohistochemical distribution of Toll-like receptor 4 in term and preterm human placentas from normal and complicated pregnancy including chorioamnionitis. Hum Pathol35: 47-54.
24. Levy, O. (2007) Innate immunity of the newborn: basic mechanisms and clinical correlates. Nat Rev Immunol7: 379-390.
25. Liu, H., Redline, R.W. and Han, Y.W. (2007) Fusobacterium nucleatum induces fetal death in mice via stimulation of TLR4-mediated placental inflammatory response. J Immunol179: 2501-2508.
26. MacDorman, M.F., Martin, J.A., Mathews, T.J., Hoyert, D.L. and Ventura, S.J. (2005) Explaining the 2001-2002 infant mortality increase in the United States: data from the linked birth/infant death data set. Int J Health Serv35: 415-442.
27. Macuch, P.J. and Tanner, A.C. (2000) Campylobacter species in health, gingivitis, and periodontitis. J Dent Res79: 785-792.
28. Madianos, P.N., Lieff, S., Murtha, A.P. et al. (2001) Maternal periodontitis and prematurity. Part II: maternal infection and fetal exposure. Ann Periodontol6: 175-182.
29. Mor, G. (2008) Inflammation and pregnancy: the role of toll-like receptors in trophoblast-immune interaction. Ann N Y Acad Sci1127: 121-128.
30. Offenbacher, S., Riche, E.L., Barros, S.P., Bobetsis, Y.A., Lin, D. and Beck, J.D. (2005) Effects of maternal Campylobacter rectus infection on murine placenta, fetal and neonatal survival, and brain development. J Periodontol76: 2133-2143.
31. Ogura, N., Shibata, Y., Matsuda, U. et al. (1995) Effect of Campylobacter rectus LPS on plasminogen activator-plasmin system in human gingival fibroblast cells. J Periodontal Res30: 132-140.
32. Ogura, N., Matsuda, U., Tanaka, F., Shibata, Y., Takiguchi, H. and Abiko, Y. (1996) In vitro senescence enhances IL-6 production in human gingival fibroblasts induced by lipopolysaccharide from Campylobacter rectus. Mech Ageing Dev87: 47-59.
33. O'Sullivan, A.M., Dore, C.J., Boyle, S., Coid, C.R. and Johnson, A.P. (1988a) The effect of campylobacter lipopolysaccharide on fetal development in the mouse. J Med Microbiol26: 101-105.
34. O'Sullivan, A.M., Dore, C.J. and Coid, C.R. (1988b) Campylobacters and impaired fetal development in mice. J Med Microbiol25: 7-12.
35. Patni, S., Flynn, P., Wynen, L.P. et al. (2007) An introduction to Toll-like receptors and their possible role in the initiation of labour. BJOG114: 1326-1334.
36. Pattillo, R.A. and Gey, G.O. (1968) The establishment of a cell line of human hormone-synthesizing trophoblastic cells in vitro. Cancer Res28: 1231-1236.
37. Rams, T.E., Feik, D. and Slots, J. (1993) Campylobacter rectus in human periodontitis. Oral Microbiol Immunol8: 230-235.
38. Romero, R., Mazor, M., Munoz, H., Gomez, R., Galasso, M. and Sherer, D.M. (1994) The preterm labor syndrome. Ann N Y Acad Sci734: 414-429.
39. Romero, R., Espinoza, J., Kusanovic, J.P. et al. (2006) The preterm parturition syndrome. BJOG113(Suppl. 3): 17-42.
40. Romero, R., Espinoza, J., Goncalves, L.F., Kusanovic, J.P., Friel, L. and Hassan, S. (2007) The role of inflammation and infection in preterm birth. Semin Reprod Med25: 21-39.
41. Ruma, M., Boggess, K., Moss, K. et al. (2008) Maternal periodontal disease, systemic inflammation, and risk for preeclampsia. Am J Obstet Gynecol198: 389-395.
42. 2 in human choriodecidua. J Reprod Immunol75: 82-90.
43. 2 release from human gingival fibroblasts. Oral Dis2: 202-209.
44. Uematsu, S. and Akira, S. (2006) Toll-like receptors and innate immunity. J Mol Med84: 712-725.
45. Wang, H. and Hirsch, E. (2003) Bacterially-induced preterm labor and regulation of prostaglandin-metabolizing enzyme expression in mice: the role of toll-like receptor 4. Biol Reprod69: 1957-1963.
46. WHO (1970) The prevention of perinatal mortality and morbidity. Report of a WHO Expert Committee. World Health Organ Tech Rep Ser457: 1-60.
47. Yeo, A., Smith, M.A., Lin, D. et al. (2005) Campylobacter rectus mediates growth restriction in pregnant mice. J Periodontol76: 551-557.
48. Yokoyama, M., Hinode, D., Yoshioka, M. et al. (2008) Relationship between Campylobacter rectus and periodontal status during pregnancy. Oral Microbiol Immunol23: 55-59.