-
1
-
-
84933064751
-
A partially inactivating mutation in the sodium-dependent lysophosphatidylcholine transporter MFSD2A causes a non-lethal microcephaly syndrome
-
V. Alakbarzade, A. Hameed, D.Q.Y. Quek, B.A. Chioza, E.L. Baple, A. Cazenave-Gassiot, L.N. Nguyen, M.R. Wenk, A.Q. Ahmad, A. Sreekantan-Nair, and et al. A partially inactivating mutation in the sodium-dependent lysophosphatidylcholine transporter MFSD2A causes a non-lethal microcephaly syndrome Nat. Genet. 47 2015 814 817
-
(2015)
Nat. Genet.
, vol.47
, pp. 814-817
-
-
Alakbarzade, V.1
Hameed, A.2
Quek, D.Q.Y.3
Chioza, B.A.4
Baple, E.L.5
Cazenave-Gassiot, A.6
Nguyen, L.N.7
Wenk, M.R.8
Ahmad, A.Q.9
Sreekantan-Nair, A.10
-
2
-
-
34250694970
-
Merosin-negative congenital muscular dystrophy: Diffusion-weighted imaging findings of brain
-
A. Alkan, A. Sigirci, R. Kutlu, M. Aslan, S. Doganay, and C. Yakinci Merosin-negative congenital muscular dystrophy: diffusion-weighted imaging findings of brain J. Child Neurol. 22 2007 655 659
-
(2007)
J. Child Neurol.
, vol.22
, pp. 655-659
-
-
Alkan, A.1
Sigirci, A.2
Kutlu, R.3
Aslan, M.4
Doganay, S.5
Yakinci, C.6
-
3
-
-
84455205524
-
The Hedgehog pathway promotes blood-brain barrier integrity and CNS immune quiescence
-
J.I. Alvarez, A. Dodelet-Devillers, H. Kebir, I. Ifergan, P.J. Fabre, S. Terouz, M. Sabbagh, K. Wosik, L. Bourbonnière, M. Bernard, and et al. The Hedgehog pathway promotes blood-brain barrier integrity and CNS immune quiescence Science 334 2011 1727 1731
-
(2011)
Science
, vol.334
, pp. 1727-1731
-
-
Alvarez, J.I.1
Dodelet-Devillers, A.2
Kebir, H.3
Ifergan, I.4
Fabre, P.J.5
Terouz, S.6
Sabbagh, M.7
Wosik, K.8
Bourbonnière, L.9
Bernard, M.10
-
5
-
-
78649467527
-
Pericytes regulate the blood-brain barrier
-
A. Armulik, G. Genové, M. Mäe, M.H. Nisancioglu, E. Wallgard, C. Niaudet, L. He, J. Norlin, P. Lindblom, K. Strittmatter, and et al. Pericytes regulate the blood-brain barrier Nature 468 2010 557 561
-
(2010)
Nature
, vol.468
, pp. 557-561
-
-
Armulik, A.1
Genové, G.2
Mäe, M.3
Nisancioglu, M.H.4
Wallgard, E.5
Niaudet, C.6
He, L.7
Norlin, J.8
Lindblom, P.9
Strittmatter, K.10
-
6
-
-
79961230399
-
Pericytes: Developmental, physiological, and pathological perspectives, problems, and promises
-
A. Armulik, G. Genové, and C. Betsholtz Pericytes: developmental, physiological, and pathological perspectives, problems, and promises Dev. Cell 21 2011 193 215
-
(2011)
Dev. Cell
, vol.21
, pp. 193-215
-
-
Armulik, A.1
Genové, G.2
Betsholtz, C.3
-
7
-
-
84942469639
-
A dural lymphatic vascular system that drains brain interstitial fluid and macromolecules
-
A. Aspelund, S. Antila, S.T. Proulx, T.V. Karlsen, S. Karaman, M. Detmar, H. Wiig, and K. Alitalo A dural lymphatic vascular system that drains brain interstitial fluid and macromolecules J. Exp. Med. 212 2015 991 999
-
(2015)
J. Exp. Med.
, vol.212
, pp. 991-999
-
-
Aspelund, A.1
Antila, S.2
Proulx, S.T.3
Karlsen, T.V.4
Karaman, S.5
Detmar, M.6
Wiig, H.7
Alitalo, K.8
-
8
-
-
78149425848
-
Glial and neuronal control of brain blood flow
-
D. Attwell, A.M. Buchan, S. Charpak, M. Lauritzen, B.A. Macvicar, and E.A. Newman Glial and neuronal control of brain blood flow Nature 468 2010 232 243
-
(2010)
Nature
, vol.468
, pp. 232-243
-
-
Attwell, D.1
Buchan, A.M.2
Charpak, S.3
Lauritzen, M.4
Macvicar, B.A.5
Newman, E.A.6
-
9
-
-
0035984815
-
Brain clearance of Alzheimer's amyloid-beta40 in the squirrel monkey: A SPECT study in a primate model of cerebral amyloid angiopathy
-
J.R. Bading, S. Yamada, J.B. Mackic, L. Kirkman, C. Miller, M. Calero, J. Ghiso, B. Frangione, and B.V. Zlokovic Brain clearance of Alzheimer's amyloid-beta40 in the squirrel monkey: a SPECT study in a primate model of cerebral amyloid angiopathy J. Drug Target. 10 2002 359 368
-
(2002)
J. Drug Target.
, vol.10
, pp. 359-368
-
-
Bading, J.R.1
Yamada, S.2
Mackic, J.B.3
Kirkman, L.4
Miller, C.5
Calero, M.6
Ghiso, J.7
Frangione, B.8
Zlokovic, B.V.9
-
10
-
-
80053924042
-
Extracellular matrix and matrix receptors in blood-brain barrier formation and stroke
-
K.M. Baeten, and K. Akassoglou Extracellular matrix and matrix receptors in blood-brain barrier formation and stroke Dev. Neurobiol. 71 2011 1018 1039
-
(2011)
Dev. Neurobiol.
, vol.71
, pp. 1018-1039
-
-
Baeten, K.M.1
Akassoglou, K.2
-
11
-
-
84867581572
-
The vascular factor in Alzheimer's disease: A study in Golgi technique and electron microscopy
-
S.J. Baloyannis, and I.S. Baloyannis The vascular factor in Alzheimer's disease: a study in Golgi technique and electron microscopy J. Neurol. Sci. 322 2012 117 121
-
(2012)
J. Neurol. Sci.
, vol.322
, pp. 117-121
-
-
Baloyannis, S.J.1
Baloyannis, I.S.2
-
12
-
-
34247506244
-
Transport pathways for clearance of human Alzheimer's amyloid beta-peptide and apolipoproteins E and J in the mouse central nervous system
-
R.D. Bell, A.P. Sagare, A.E. Friedman, G.S. Bedi, D.M. Holtzman, R. Deane, and B.V. Zlokovic Transport pathways for clearance of human Alzheimer's amyloid beta-peptide and apolipoproteins E and J in the mouse central nervous system J. Cereb. Blood Flow Metab. 27 2007 909 918
-
(2007)
J. Cereb. Blood Flow Metab.
, vol.27
, pp. 909-918
-
-
Bell, R.D.1
Sagare, A.P.2
Friedman, A.E.3
Bedi, G.S.4
Holtzman, D.M.5
Deane, R.6
Zlokovic, B.V.7
-
13
-
-
78049279739
-
Pericytes control key neurovascular functions and neuronal phenotype in the adult brain and during brain aging
-
R.D. Bell, E.A. Winkler, A.P. Sagare, I. Singh, B. LaRue, R. Deane, and B.V. Zlokovic Pericytes control key neurovascular functions and neuronal phenotype in the adult brain and during brain aging Neuron 68 2010 409 427
-
(2010)
Neuron
, vol.68
, pp. 409-427
-
-
Bell, R.D.1
Winkler, E.A.2
Sagare, A.P.3
Singh, I.4
LaRue, B.5
Deane, R.6
Zlokovic, B.V.7
-
14
-
-
84861418194
-
Apolipoprotein E controls cerebrovascular integrity via cyclophilin A
-
R.D. Bell, E.A. Winkler, I. Singh, A.P. Sagare, R. Deane, Z. Wu, D.M. Holtzman, C. Betsholtz, A. Armulik, J. Sallstrom, and et al. Apolipoprotein E controls cerebrovascular integrity via cyclophilin A Nature 485 2012 512 516
-
(2012)
Nature
, vol.485
, pp. 512-516
-
-
Bell, R.D.1
Winkler, E.A.2
Singh, I.3
Sagare, A.P.4
Deane, R.5
Wu, Z.6
Holtzman, D.M.7
Betsholtz, C.8
Armulik, A.9
Sallstrom, J.10
-
15
-
-
84901269974
-
Mfsd2a is critical for the formation and function of the blood-brain barrier
-
A. Ben-Zvi, B. Lacoste, E. Kur, B.J. Andreone, Y. Mayshar, H. Yan, and C. Gu Mfsd2a is critical for the formation and function of the blood-brain barrier Nature 509 2014 507 511
-
(2014)
Nature
, vol.509
, pp. 507-511
-
-
Ben-Zvi, A.1
Lacoste, B.2
Kur, E.3
Andreone, B.J.4
Mayshar, Y.5
Yan, H.6
Gu, C.7
-
16
-
-
84902075886
-
Brain glucose transporters: Implications for neurologic disease
-
E.E. Benarroch Brain glucose transporters: implications for neurologic disease Neurology 82 2014 1374 1379
-
(2014)
Neurology
, vol.82
, pp. 1374-1379
-
-
Benarroch, E.E.1
-
17
-
-
84901267568
-
Physiology: Double function at the blood-brain barrier
-
C. Betsholtz Physiology: Double function at the blood-brain barrier Nature 509 2014 432 433
-
(2014)
Nature
, vol.509
, pp. 432-433
-
-
Betsholtz, C.1
-
18
-
-
84933036615
-
Lipid transport and human brain development
-
C. Betsholtz Lipid transport and human brain development Nat. Genet. 47 2015 699 701
-
(2015)
Nat. Genet.
, vol.47
, pp. 699-701
-
-
Betsholtz, C.1
-
19
-
-
84879696778
-
The cortical angiome: An interconnected vascular network with noncolumnar patterns of blood flow
-
P. Blinder, P.S. Tsai, J.P. Kaufhold, P.M. Knutsen, H. Suhl, and D. Kleinfeld The cortical angiome: an interconnected vascular network with noncolumnar patterns of blood flow Nat. Neurosci. 16 2013 889 897
-
(2013)
Nat. Neurosci.
, vol.16
, pp. 889-897
-
-
Blinder, P.1
Tsai, P.S.2
Kaufhold, J.P.3
Knutsen, P.M.4
Suhl, H.5
Kleinfeld, D.6
-
20
-
-
84926095809
-
Biologics: Transferrin' bispecific antibodies across the blood-brain barrier
-
N. Bray Biologics: Transferrin' bispecific antibodies across the blood-brain barrier Nat. Rev. Drug Discov. 14 2015 14 15
-
(2015)
Nat. Rev. Drug Discov.
, vol.14
, pp. 14-15
-
-
Bray, N.1
-
21
-
-
84879416326
-
Relevance of different cellular models in determining the effects of mutations on SLC16A2/MCT8 thyroid hormone transporter function and genotype-phenotype correlation
-
Y. Capri, E.C.H. Friesema, S. Kersseboom, R. Touraine, A. Monnier, E. Eymard-Pierre, V. Des Portes, G. De Michele, A.F. Brady, O. Boespflug-Tanguy, and et al. Relevance of different cellular models in determining the effects of mutations on SLC16A2/MCT8 thyroid hormone transporter function and genotype-phenotype correlation Hum. Mutat. 34 2013 1018 1025
-
(2013)
Hum. Mutat.
, vol.34
, pp. 1018-1025
-
-
Capri, Y.1
Friesema, E.C.H.2
Kersseboom, S.3
Touraine, R.4
Monnier, A.5
Eymard-Pierre, E.6
Des Portes, V.7
De Michele, G.8
Brady, A.F.9
Boespflug-Tanguy, O.10
-
22
-
-
67649389481
-
Cadasil
-
H. Chabriat, A. Joutel, M. Dichgans, E. Tournier-Lasserve, and M.-G. Bousser Cadasil Lancet Neurol. 8 2009 643 653
-
(2009)
Lancet Neurol.
, vol.8
, pp. 643-653
-
-
Chabriat, H.1
Joutel, A.2
Dichgans, M.3
Tournier-Lasserve, E.4
Bousser, M.-G.5
-
23
-
-
27644489474
-
P-glycoprotein deficiency at the blood-brain barrier increases amyloid-beta deposition in an Alzheimer disease mouse model
-
J.R. Cirrito, R. Deane, A.M. Fagan, M.L. Spinner, M. Parsadanian, M.B. Finn, H. Jiang, J.L. Prior, A. Sagare, K.R. Bales, and et al. P-glycoprotein deficiency at the blood-brain barrier increases amyloid-beta deposition in an Alzheimer disease mouse model J. Clin. Invest. 115 2005 3285 3290
-
(2005)
J. Clin. Invest.
, vol.115
, pp. 3285-3290
-
-
Cirrito, J.R.1
Deane, R.2
Fagan, A.M.3
Spinner, M.L.4
Parsadanian, M.5
Finn, M.B.6
Jiang, H.7
Prior, J.L.8
Sagare, A.9
Bales, K.R.10
-
24
-
-
84876668625
-
Emerging roles of astrocytes in neural circuit development
-
L.E. Clarke, and B.A. Barres Emerging roles of astrocytes in neural circuit development Nat. Rev. Neurosci. 14 2013 311 321
-
(2013)
Nat. Rev. Neurosci.
, vol.14
, pp. 311-321
-
-
Clarke, L.E.1
Barres, B.A.2
-
26
-
-
58849119932
-
Wnt/beta-catenin signaling is required for CNS, but not non-CNS, angiogenesis
-
R. Daneman, D. Agalliu, L. Zhou, F. Kuhnert, C.J. Kuo, and B.A. Barres Wnt/beta-catenin signaling is required for CNS, but not non-CNS, angiogenesis Proc. Natl. Acad. Sci. USA 106 2009 641 646
-
(2009)
Proc. Natl. Acad. Sci. USA
, vol.106
, pp. 641-646
-
-
Daneman, R.1
Agalliu, D.2
Zhou, L.3
Kuhnert, F.4
Kuo, C.J.5
Barres, B.A.6
-
27
-
-
78649487239
-
Pericytes are required for blood-brain barrier integrity during embryogenesis
-
R. Daneman, L. Zhou, A.A. Kebede, and B.A. Barres Pericytes are required for blood-brain barrier integrity during embryogenesis Nature 468 2010 562 566
-
(2010)
Nature
, vol.468
, pp. 562-566
-
-
Daneman, R.1
Zhou, L.2
Kebede, A.A.3
Barres, B.A.4
-
28
-
-
84870815173
-
Fibrinogen-induced perivascular microglial clustering is required for the development of axonal damage in neuroinflammation
-
D. Davalos, J.K. Ryu, M. Merlini, K.M. Baeten, N. Le Moan, M.A. Petersen, T.J. Deerinck, D.S. Smirnoff, C. Bedard, H. Hakozaki, and et al. Fibrinogen-induced perivascular microglial clustering is required for the development of axonal damage in neuroinflammation Nat. Commun. 3 2012 1227
-
(2012)
Nat. Commun.
, vol.3
, pp. 1227
-
-
Davalos, D.1
Ryu, J.K.2
Merlini, M.3
Baeten, K.M.4
Le Moan, N.5
Petersen, M.A.6
Deerinck, T.J.7
Smirnoff, D.S.8
Bedard, C.9
Hakozaki, H.10
-
29
-
-
0037703255
-
RAGE mediates amyloid-beta peptide transport across the blood-brain barrier and accumulation in brain
-
R. Deane, S. Du Yan, R.K. Submamaryan, B. LaRue, S. Jovanovic, E. Hogg, D. Welch, L. Manness, C. Lin, J. Yu, and et al. RAGE mediates amyloid-beta peptide transport across the blood-brain barrier and accumulation in brain Nat. Med. 9 2003 907 913
-
(2003)
Nat. Med.
, vol.9
, pp. 907-913
-
-
Deane, R.1
Du Yan, S.2
Submamaryan, R.K.3
LaRue, B.4
Jovanovic, S.5
Hogg, E.6
Welch, D.7
Manness, L.8
Lin, C.9
Yu, J.10
-
30
-
-
4043061467
-
LRP/amyloid beta-peptide interaction mediates differential brain efflux of Abeta isoforms
-
R. Deane, Z. Wu, A. Sagare, J. Davis, S. Du Yan, K. Hamm, F. Xu, M. Parisi, B. LaRue, H.W. Hu, and et al. LRP/amyloid beta-peptide interaction mediates differential brain efflux of Abeta isoforms Neuron 43 2004 333 344
-
(2004)
Neuron
, vol.43
, pp. 333-344
-
-
Deane, R.1
Wu, Z.2
Sagare, A.3
Davis, J.4
Du Yan, S.5
Hamm, K.6
Xu, F.7
Parisi, M.8
LaRue, B.9
Hu, H.W.10
-
31
-
-
57449084208
-
ApoE isoform-specific disruption of amyloid beta peptide clearance from mouse brain
-
R. Deane, A. Sagare, K. Hamm, M. Parisi, S. Lane, M.B. Finn, D.M. Holtzman, and B.V. Zlokovic apoE isoform-specific disruption of amyloid beta peptide clearance from mouse brain J. Clin. Invest. 118 2008 4002 4013
-
(2008)
J. Clin. Invest.
, vol.118
, pp. 4002-4013
-
-
Deane, R.1
Sagare, A.2
Hamm, K.3
Parisi, M.4
Lane, S.5
Finn, M.B.6
Holtzman, D.M.7
Zlokovic, B.V.8
-
32
-
-
84859723641
-
A multimodal RAGE-specific inhibitor reduces amyloid β-mediated brain disorder in a mouse model of Alzheimer disease
-
R. Deane, I. Singh, A.P. Sagare, R.D. Bell, N.T. Ross, B. LaRue, R. Love, S. Perry, N. Paquette, R.J. Deane, and et al. A multimodal RAGE-specific inhibitor reduces amyloid β-mediated brain disorder in a mouse model of Alzheimer disease J. Clin. Invest. 122 2012 1377 1392
-
(2012)
J. Clin. Invest.
, vol.122
, pp. 1377-1392
-
-
Deane, R.1
Singh, I.2
Sagare, A.P.3
Bell, R.D.4
Ross, N.T.5
LaRue, B.6
Love, R.7
Perry, S.8
Paquette, N.9
Deane, R.J.10
-
33
-
-
84937730922
-
Cerebrovascular and blood-brain barrier impairments in Huntington's disease: Potential implications for its pathophysiology
-
J. Drouin-Ouellet, S.J. Sawiak, G. Cisbani, M. Lagacé, W.-L. Kuan, M. Saint-Pierre, R.J. Dury, W. Alata, I. St-Amour, S.L. Mason, and et al. Cerebrovascular and blood-brain barrier impairments in Huntington's disease: Potential implications for its pathophysiology Ann. Neurol. 78 2015 160 177
-
(2015)
Ann. Neurol.
, vol.78
, pp. 160-177
-
-
Drouin-Ouellet, J.1
Sawiak, S.J.2
Cisbani, G.3
Lagacé, M.4
Kuan, W.-L.5
Saint-Pierre, M.6
Dury, R.J.7
Alata, W.8
St-Amour, I.9
Mason, S.L.10
-
34
-
-
0347634343
-
A novel syndrome combining thyroid and neurological abnormalities is associated with mutations in a monocarboxylate transporter gene
-
A.M. Dumitrescu, X.-H. Liao, T.B. Best, K. Brockmann, and S. Refetoff A novel syndrome combining thyroid and neurological abnormalities is associated with mutations in a monocarboxylate transporter gene Am. J. Hum. Genet. 74 2004 168 175
-
(2004)
Am. J. Hum. Genet.
, vol.74
, pp. 168-175
-
-
Dumitrescu, A.M.1
Liao, X.-H.2
Best, T.B.3
Brockmann, K.4
Refetoff, S.5
-
35
-
-
0035047718
-
Cerebral microvascular pathology in aging and Alzheimer's disease
-
E. Farkas, and P.G. Luiten Cerebral microvascular pathology in aging and Alzheimer's disease Prog. Neurobiol. 64 2001 575 611
-
(2001)
Prog. Neurobiol.
, vol.64
, pp. 575-611
-
-
Farkas, E.1
Luiten, P.G.2
-
36
-
-
84877106886
-
Cerebral cavernous malformations: From CCM genes to endothelial cell homeostasis
-
A. Fischer, J. Zalvide, E. Faurobert, C. Albiges-Rizo, and E. Tournier-Lasserve Cerebral cavernous malformations: from CCM genes to endothelial cell homeostasis Trends Mol. Med. 19 2013 302 308
-
(2013)
Trends Mol. Med.
, vol.19
, pp. 302-308
-
-
Fischer, A.1
Zalvide, J.2
Faurobert, E.3
Albiges-Rizo, C.4
Tournier-Lasserve, E.5
-
37
-
-
5644276275
-
Association between mutations in a thyroid hormone transporter and severe X-linked psychomotor retardation
-
E.C.H. Friesema, A. Grueters, H. Biebermann, H. Krude, A. von Moers, M. Reeser, T.G. Barrett, E.E. Mancilla, J. Svensson, M.H.A. Kester, and et al. Association between mutations in a thyroid hormone transporter and severe X-linked psychomotor retardation Lancet 364 2004 1435 1437
-
(2004)
Lancet
, vol.364
, pp. 1435-1437
-
-
Friesema, E.C.H.1
Grueters, A.2
Biebermann, H.3
Krude, H.4
Von Moers, A.5
Reeser, M.6
Barrett, T.G.7
Mancilla, E.E.8
Svensson, J.9
Kester, M.H.A.10
-
38
-
-
73949119034
-
Age-related vascular pathology in transgenic mice expressing presenilin 1-associated familial Alzheimer's disease mutations
-
M.A. Gama Sosa, R.D. Gasperi, A.B. Rocher, A.C.-J. Wang, W.G.M. Janssen, T. Flores, G.M. Perez, J. Schmeidler, D.L. Dickstein, P.R. Hof, and G.A. Elder Age-related vascular pathology in transgenic mice expressing presenilin 1-associated familial Alzheimer's disease mutations Am. J. Pathol. 176 2010 353 368
-
(2010)
Am. J. Pathol.
, vol.176
, pp. 353-368
-
-
Gama Sosa, M.A.1
Gasperi, R.D.2
Rocher, A.B.3
Wang, A.C.-J.4
Janssen, W.G.M.5
Flores, T.6
Perez, G.M.7
Schmeidler, J.8
Dickstein, D.L.9
Hof, P.R.10
Elder, G.A.11
-
39
-
-
33645498692
-
Role of COL4A1 in small-vessel disease and hemorrhagic stroke
-
D.B. Gould, F.C. Phalan, S.E. van Mil, J.P. Sundberg, K. Vahedi, P. Massin, M.G. Bousser, P. Heutink, J.H. Miner, E. Tournier-Lasserve, and S.W. John Role of COL4A1 in small-vessel disease and hemorrhagic stroke N. Engl. J. Med. 354 2006 1489 1496
-
(2006)
N. Engl. J. Med.
, vol.354
, pp. 1489-1496
-
-
Gould, D.B.1
Phalan, F.C.2
Van Mil, S.E.3
Sundberg, J.P.4
Vahedi, K.5
Massin, P.6
Bousser, M.G.7
Heutink, P.8
Miner, J.H.9
Tournier-Lasserve, E.10
John, S.W.11
-
40
-
-
84933040235
-
Inactivating mutations in MFSD2A, required for omega-3 fatty acid transport in brain, cause a lethal microcephaly syndrome
-
A. Guemez-Gamboa, L.N. Nguyen, H. Yang, M.S. Zaki, M. Kara, T. Ben-Omran, N. Akizu, R.O. Rosti, B. Rosti, E. Scott, and et al. Inactivating mutations in MFSD2A, required for omega-3 fatty acid transport in brain, cause a lethal microcephaly syndrome Nat. Genet. 47 2015 809 813
-
(2015)
Nat. Genet.
, vol.47
, pp. 809-813
-
-
Guemez-Gamboa, A.1
Nguyen, L.N.2
Yang, H.3
Zaki, M.S.4
Kara, M.5
Ben-Omran, T.6
Akizu, N.7
Rosti, R.O.8
Rosti, B.9
Scott, E.10
-
41
-
-
84928213789
-
The molecular, cellular, and morphological components of blood-brain barrier development during embryogenesis
-
N. Hagan, and A. Ben-Zvi The molecular, cellular, and morphological components of blood-brain barrier development during embryogenesis Semin. Cell Dev. Biol. 38 2015 7 15
-
(2015)
Semin. Cell Dev. Biol.
, vol.38
, pp. 7-15
-
-
Hagan, N.1
Ben-Zvi, A.2
-
42
-
-
84897564199
-
Capillary pericytes regulate cerebral blood flow in health and disease
-
C.N. Hall, C. Reynell, B. Gesslein, N.B. Hamilton, A. Mishra, B.A. Sutherland, F.M. O'Farrell, A.M. Buchan, M. Lauritzen, and D. Attwell Capillary pericytes regulate cerebral blood flow in health and disease Nature 508 2014 55 60
-
(2014)
Nature
, vol.508
, pp. 55-60
-
-
Hall, C.N.1
Reynell, C.2
Gesslein, B.3
Hamilton, N.B.4
Mishra, A.5
Sutherland, B.A.6
O'Farrell, F.M.7
Buchan, A.M.8
Lauritzen, M.9
Attwell, D.10
-
43
-
-
84883796045
-
Relationship between cyclophilin a levels and matrix metalloproteinase 9 activity in cerebrospinal fluid of cognitively normal apolipoprotein e4 carriers and blood-brain barrier breakdown
-
M.R. Halliday, N. Pomara, A.P. Sagare, W.J. Mack, B. Frangione, and B.V. Zlokovic Relationship between cyclophilin a levels and matrix metalloproteinase 9 activity in cerebrospinal fluid of cognitively normal apolipoprotein e4 carriers and blood-brain barrier breakdown JAMA Neurol. 70 2013 1198 1200
-
(2013)
JAMA Neurol.
, vol.70
, pp. 1198-1200
-
-
Halliday, M.R.1
Pomara, N.2
Sagare, A.P.3
Mack, W.J.4
Frangione, B.5
Zlokovic, B.V.6
-
44
-
-
84951568640
-
Accelerated pericyte degeneration and blood-brain barrier breakdown in apolipoprotein E4 carriers with Alzheimer's disease
-
M.R. Halliday, S.V. Rege, Q. Ma, Z. Zhao, C.A. Miller, E.A. Winkler, and B.V. Zlokovic Accelerated pericyte degeneration and blood-brain barrier breakdown in apolipoprotein E4 carriers with Alzheimer's disease J. Cereb. Blood Flow Metab. Off. J. Int. Soc. Cereb. Blood Flow Metab. 2015 10.1038/jcbfm.2015.44
-
(2015)
J. Cereb. Blood Flow Metab. Off. J. Int. Soc. Cereb. Blood Flow Metab.
-
-
Halliday, M.R.1
Rege, S.V.2
Ma, Q.3
Zhao, Z.4
Miller, C.A.5
Winkler, E.A.6
Zlokovic, B.V.7
-
45
-
-
84920889270
-
Neuropsychiatric disease relevance of circulating anti-NMDA receptor autoantibodies depends on blood-brain barrier integrity
-
C. Hammer, B. Stepniak, A. Schneider, S. Papiol, M. Tantra, M. Begemann, A.-L. Sirén, L.A. Pardo, S. Sperling, S. Mohd Jofrry, and et al. Neuropsychiatric disease relevance of circulating anti-NMDA receptor autoantibodies depends on blood-brain barrier integrity Mol. Psychiatry 19 2014 1143 1149
-
(2014)
Mol. Psychiatry
, vol.19
, pp. 1143-1149
-
-
Hammer, C.1
Stepniak, B.2
Schneider, A.3
Papiol, S.4
Tantra, M.5
Begemann, M.6
Sirén, A.-L.7
Pardo, L.A.8
Sperling, S.9
Mohd Jofrry, S.10
-
46
-
-
70349558522
-
Genome-wide association study identifies variants at CLU and PICALM associated with Alzheimer's disease
-
D. Harold, R. Abraham, P. Hollingworth, R. Sims, A. Gerrish, M.L. Hamshere, J.S. Pahwa, V. Moskvina, K. Dowzell, A. Williams, and et al. Genome-wide association study identifies variants at CLU and PICALM associated with Alzheimer's disease Nat. Genet. 41 2009 1088 1093
-
(2009)
Nat. Genet.
, vol.41
, pp. 1088-1093
-
-
Harold, D.1
Abraham, R.2
Hollingworth, P.3
Sims, R.4
Gerrish, A.5
Hamshere, M.L.6
Pahwa, J.S.7
Moskvina, V.8
Dowzell, K.9
Williams, A.10
-
47
-
-
84922007858
-
Notch3 is necessary for blood vessel integrity in the central nervous system
-
T.L. Henshall, A. Keller, L. He, B.R. Johansson, E. Wallgard, E. Raschperger, M.A. Mäe, S. Jin, C. Betsholtz, and U. Lendahl Notch3 is necessary for blood vessel integrity in the central nervous system Arterioscler. Thromb. Vasc. Biol. 35 2015 409 420
-
(2015)
Arterioscler. Thromb. Vasc. Biol.
, vol.35
, pp. 409-420
-
-
Henshall, T.L.1
Keller, A.2
He, L.3
Johansson, B.R.4
Wallgard, E.5
Raschperger, E.6
Mäe, M.A.7
Jin, S.8
Betsholtz, C.9
Lendahl, U.10
-
48
-
-
84881181605
-
The APOE ε4/ε4 genotype potentiates vascular fibrin(ogen) deposition in amyloid-laden vessels in the brains of Alzheimer's disease patients
-
K. Hultman, S. Strickland, and E.H. Norris The APOE ε4/ε4 genotype potentiates vascular fibrin(ogen) deposition in amyloid-laden vessels in the brains of Alzheimer's disease patients J. Cereb. Blood Flow Metab. 33 2013 1251 1258
-
(2013)
J. Cereb. Blood Flow Metab.
, vol.33
, pp. 1251-1258
-
-
Hultman, K.1
Strickland, S.2
Norris, E.H.3
-
49
-
-
84888019151
-
The pathobiology of vascular dementia
-
C. Iadecola The pathobiology of vascular dementia Neuron 80 2013 844 866
-
(2013)
Neuron
, vol.80
, pp. 844-866
-
-
Iadecola, C.1
-
50
-
-
84883463387
-
Mutations in the gene encoding PDGF-B cause brain calcifications in humans and mice
-
A. Keller, A. Westenberger, M.J. Sobrido, M. García-Murias, A. Domingo, R.L. Sears, R.R. Lemos, A. Ordoñez-Ugalde, G. Nicolas, J.E.G. da Cunha, and et al. Mutations in the gene encoding PDGF-B cause brain calcifications in humans and mice Nat. Genet. 45 2013 1077 1082
-
(2013)
Nat. Genet.
, vol.45
, pp. 1077-1082
-
-
Keller, A.1
Westenberger, A.2
Sobrido, M.J.3
García-Murias, M.4
Domingo, A.5
Sears, R.L.6
Lemos, R.R.7
Ordoñez-Ugalde, A.8
Nicolas, G.9
Da Cunha, J.E.G.10
-
51
-
-
84876880669
-
Mutations in MCT8 in patients with Allan-Herndon-Dudley-syndrome affecting its cellular distribution
-
S. Kersseboom, G.-J. Kremers, E.C.H. Friesema, W.E. Visser, W. Klootwijk, R.P. Peeters, and T.J. Visser Mutations in MCT8 in patients with Allan-Herndon-Dudley-syndrome affecting its cellular distribution Mol. Endocrinol. 27 2013 801 813
-
(2013)
Mol. Endocrinol.
, vol.27
, pp. 801-813
-
-
Kersseboom, S.1
Kremers, G.-J.2
Friesema, E.C.H.3
Visser, W.E.4
Klootwijk, W.5
Peeters, R.P.6
Visser, T.J.7
-
52
-
-
84930572793
-
Vascular parkinsonism - Characteristics, pathogenesis and treatment
-
A.D. Korczyn Vascular parkinsonism - characteristics, pathogenesis and treatment Nat. Rev. Neurol. 11 2015 319 326
-
(2015)
Nat. Rev. Neurol.
, vol.11
, pp. 319-326
-
-
Korczyn, A.D.1
-
53
-
-
78149399666
-
Essential regulation of CNS angiogenesis by the orphan G protein-coupled receptor GPR124
-
F. Kuhnert, M.R. Mancuso, A. Shamloo, H.-T. Wang, V. Choksi, M. Florek, H. Su, M. Fruttiger, W.L. Young, S.C. Heilshorn, and C.J. Kuo Essential regulation of CNS angiogenesis by the orphan G protein-coupled receptor GPR124 Science 330 2010 985 989
-
(2010)
Science
, vol.330
, pp. 985-989
-
-
Kuhnert, F.1
Mancuso, M.R.2
Shamloo, A.3
Wang, H.-T.4
Choksi, V.5
Florek, M.6
Su, H.7
Fruttiger, M.8
Young, W.L.9
Heilshorn, S.C.10
Kuo, C.J.11
-
54
-
-
84867124426
-
COL4A1 and COL4A2 mutations and disease: Insights into pathogenic mechanisms and potential therapeutic targets
-
D.S. Kuo, C. Labelle-Dumais, and D.B. Gould COL4A1 and COL4A2 mutations and disease: insights into pathogenic mechanisms and potential therapeutic targets Hum. Mol. Genet. 21 R1 2012 R97 R110
-
(2012)
Hum. Mol. Genet.
, vol.21
, Issue.R1
, pp. R97-R110
-
-
Kuo, D.S.1
Labelle-Dumais, C.2
Gould, D.B.3
-
55
-
-
78549264026
-
Genome-wide association study identifies variants at CLU and CR1 associated with Alzheimer's disease
-
J.-C. Lambert, S. Heath, G. Even, D. Campion, K. Sleegers, M. Hiltunen, O. Combarros, D. Zelenika, M.J. Bullido, B. Tavernier, et al. European Alzheimer's Disease Initiative Investigators Genome-wide association study identifies variants at CLU and CR1 associated with Alzheimer's disease Nat. Genet. 41 2009 1094 1099
-
(2009)
Nat. Genet.
, vol.41
, pp. 1094-1099
-
-
Lambert, J.-C.1
Heath, S.2
Even, G.3
Campion, D.4
Sleegers, K.5
Hiltunen, M.6
Combarros, O.7
Zelenika, D.8
Bullido, M.J.9
Tavernier, B.10
-
56
-
-
0037703253
-
SSeCKS regulates angiogenesis and tight junction formation in blood-brain barrier
-
S.-W. Lee, W.J. Kim, Y.K. Choi, H.S. Song, M.J. Son, I.H. Gelman, Y.-J. Kim, and K.-W. Kim SSeCKS regulates angiogenesis and tight junction formation in blood-brain barrier Nat. Med. 9 2003 900 906
-
(2003)
Nat. Med.
, vol.9
, pp. 900-906
-
-
Lee, S.-W.1
Kim, W.J.2
Choi, Y.K.3
Song, H.S.4
Son, M.J.5
Gelman, I.H.6
Kim, Y.-J.7
Kim, K.-W.8
-
57
-
-
84930087279
-
Mutations in XPR1 cause primary familial brain calcification associated with altered phosphate export
-
A. Legati, D. Giovannini, G. Nicolas, U. López-Sánchez, B. Quintáns, J.R.M. Oliveira, R.L. Sears, E.M. Ramos, E. Spiteri, M.-J. Sobrido, and et al. Mutations in XPR1 cause primary familial brain calcification associated with altered phosphate export Nat. Genet. 47 2015 579 581
-
(2015)
Nat. Genet.
, vol.47
, pp. 579-581
-
-
Legati, A.1
Giovannini, D.2
Nicolas, G.3
López-Sánchez, U.4
Quintáns, B.5
Oliveira, J.R.M.6
Sears, R.L.7
Ramos, E.M.8
Spiteri, E.9
Sobrido, M.-J.10
-
58
-
-
56149124382
-
Wnt/beta-catenin signaling controls development of the blood-brain barrier
-
S. Liebner, M. Corada, T. Bangsow, J. Babbage, A. Taddei, C.J. Czupalla, M. Reis, A. Felici, H. Wolburg, M. Fruttiger, and et al. Wnt/beta-catenin signaling controls development of the blood-brain barrier J. Cell Biol. 183 2008 409 417
-
(2008)
J. Cell Biol.
, vol.183
, pp. 409-417
-
-
Liebner, S.1
Corada, M.2
Bangsow, T.3
Babbage, J.4
Taddei, A.5
Czupalla, C.J.6
Reis, M.7
Felici, A.8
Wolburg, H.9
Fruttiger, M.10
-
60
-
-
0030756325
-
Pericyte loss and microaneurysm formation in PDGF-B-deficient mice
-
P. Lindahl, B.R. Johansson, P. Levéen, and C. Betsholtz Pericyte loss and microaneurysm formation in PDGF-B-deficient mice Science 277 1997 242 245
-
(1997)
Science
, vol.277
, pp. 242-245
-
-
Lindahl, P.1
Johansson, B.R.2
Levéen, P.3
Betsholtz, C.4
-
61
-
-
84936871460
-
Structural and functional features of central nervous system lymphatic vessels
-
A. Louveau, I. Smirnov, T.J. Keyes, J.D. Eccles, S.J. Rouhani, J.D. Peske, N.C. Derecki, D. Castle, J.W. Mandell, K.S. Lee, and et al. Structural and functional features of central nervous system lymphatic vessels Nature 523 2015 337 341
-
(2015)
Nature
, vol.523
, pp. 337-341
-
-
Louveau, A.1
Smirnov, I.2
Keyes, T.J.3
Eccles, J.D.4
Rouhani, S.J.5
Peske, J.D.6
Derecki, N.C.7
Castle, D.8
Mandell, J.W.9
Lee, K.S.10
-
62
-
-
84879690589
-
EndMT contributes to the onset and progression of cerebral cavernous malformations
-
L. Maddaluno, N. Rudini, R. Cuttano, L. Bravi, C. Giampietro, M. Corada, L. Ferrarini, F. Orsenigo, E. Papa, G. Boulday, and et al. EndMT contributes to the onset and progression of cerebral cavernous malformations Nature 498 2013 492 496
-
(2013)
Nature
, vol.498
, pp. 492-496
-
-
Maddaluno, L.1
Rudini, N.2
Cuttano, R.3
Bravi, L.4
Giampietro, C.5
Corada, M.6
Ferrarini, L.7
Orsenigo, F.8
Papa, E.9
Boulday, G.10
-
63
-
-
78650678688
-
Decreased clearance of CNS beta-amyloid in Alzheimer's disease
-
K.G. Mawuenyega, W. Sigurdson, V. Ovod, L. Munsell, T. Kasten, J.C. Morris, K.E. Yarasheski, and R.J. Bateman Decreased clearance of CNS beta-amyloid in Alzheimer's disease Science 330 2010 1774
-
(2010)
Science
, vol.330
, pp. 1774
-
-
Mawuenyega, K.G.1
Sigurdson, W.2
Ovod, V.3
Munsell, L.4
Kasten, T.5
Morris, J.C.6
Yarasheski, K.E.7
Bateman, R.J.8
-
64
-
-
84921829329
-
Regulation of ABC transporters blood-brain barrier: The good, the bad, and the ugly
-
D.S. Miller Regulation of ABC transporters blood-brain barrier: the good, the bad, and the ugly Adv. Cancer Res. 125 2015 43 70
-
(2015)
Adv. Cancer Res.
, vol.125
, pp. 43-70
-
-
Miller, D.S.1
-
65
-
-
84921326695
-
Blood-brain barrier breakdown in the aging human hippocampus
-
A. Montagne, S.R. Barnes, M.D. Sweeney, M.R. Halliday, A.P. Sagare, Z. Zhao, A.W. Toga, R.E. Jacobs, C.Y. Liu, L. Amezcua, and et al. Blood-brain barrier breakdown in the aging human hippocampus Neuron 85 2015 296 302
-
(2015)
Neuron
, vol.85
, pp. 296-302
-
-
Montagne, A.1
Barnes, S.R.2
Sweeney, M.D.3
Halliday, M.R.4
Sagare, A.P.5
Zhao, Z.6
Toga, A.W.7
Jacobs, R.E.8
Liu, C.Y.9
Amezcua, L.10
-
66
-
-
84921991249
-
Recommendations of the Alzheimer's disease-related dementias conference
-
T.J. Montine, W.J. Koroshetz, D. Babcock, D.W. Dickson, W.R. Galpern, M.M. Glymour, S.M. Greenberg, M.L. Hutton, D.S. Knopman, A.N. Kuzmichev, et al. ADRD 2013 Conference Organizing Committee Recommendations of the Alzheimer's disease-related dementias conference Neurology 83 2014 851 860
-
(2014)
Neurology
, vol.83
, pp. 851-860
-
-
Montine, T.J.1
Koroshetz, W.J.2
Babcock, D.3
Dickson, D.W.4
Galpern, W.R.5
Glymour, M.M.6
Greenberg, S.M.7
Hutton, M.L.8
Knopman, D.S.9
Kuzmichev, A.N.10
-
67
-
-
84929839390
-
Brain vascular pericytes following ischemia have multipotential stem cell activity to differentiate into neural and vascular lineage cells
-
T. Nakagomi, S. Kubo, A. Nakano-Doi, R. Sakuma, S. Lu, A. Narita, M. Kawahara, A. Taguchi, and T. Matsuyama Brain vascular pericytes following ischemia have multipotential stem cell activity to differentiate into neural and vascular lineage cells Stem Cells 33 2015 1962 1974
-
(2015)
Stem Cells
, vol.33
, pp. 1962-1974
-
-
Nakagomi, T.1
Kubo, S.2
Nakano-Doi, A.3
Sakuma, R.4
Lu, S.5
Narita, A.6
Kawahara, M.7
Taguchi, A.8
Matsuyama, T.9
-
68
-
-
84901260638
-
Mfsd2a is a transporter for the essential omega-3 fatty acid docosahexaenoic acid
-
L.N. Nguyen, D. Ma, G. Shui, P. Wong, A. Cazenave-Gassiot, X. Zhang, M.R. Wenk, E.L.K. Goh, and D.L. Silver Mfsd2a is a transporter for the essential omega-3 fatty acid docosahexaenoic acid Nature 509 2014 503 506
-
(2014)
Nature
, vol.509
, pp. 503-506
-
-
Nguyen, L.N.1
Ma, D.2
Shui, G.3
Wong, P.4
Cazenave-Gassiot, A.5
Zhang, X.6
Wenk, M.R.7
Goh, E.L.K.8
Silver, D.L.9
-
69
-
-
84873693930
-
Mutation of the PDGFRB gene as a cause of idiopathic basal ganglia calcification
-
G. Nicolas, C. Pottier, D. Maltête, S. Coutant, A. Rovelet-Lecrux, S. Legallic, S. Rousseau, Y. Vaschalde, L. Guyant-Maréchal, J. Augustin, and et al. Mutation of the PDGFRB gene as a cause of idiopathic basal ganglia calcification Neurology 80 2013 181 187
-
(2013)
Neurology
, vol.80
, pp. 181-187
-
-
Nicolas, G.1
Pottier, C.2
Maltête, D.3
Coutant, S.4
Rovelet-Lecrux, A.5
Legallic, S.6
Rousseau, S.7
Vaschalde, Y.8
Guyant-Maréchal, L.9
Augustin, J.10
-
70
-
-
77956374543
-
Recessive mutations in the gene encoding the tight junction protein occludin cause band-like calcification with simplified gyration and polymicrogyria
-
M.C. O'Driscoll, S.B. Daly, J.E. Urquhart, G.C.M. Black, D.T. Pilz, K. Brockmann, M. McEntagart, G. Abdel-Salam, M. Zaki, N.I. Wolf, and et al. Recessive mutations in the gene encoding the tight junction protein occludin cause band-like calcification with simplified gyration and polymicrogyria Am. J. Hum. Genet. 87 2010 354 364
-
(2010)
Am. J. Hum. Genet.
, vol.87
, pp. 354-364
-
-
O'Driscoll, M.C.1
Daly, S.B.2
Urquhart, J.E.3
Black, G.C.M.4
Pilz, D.T.5
Brockmann, K.6
McEntagart, M.7
Abdel-Salam, G.8
Zaki, M.9
Wolf, N.I.10
-
71
-
-
84889872057
-
Development, maintenance and disruption of the blood-brain barrier
-
B. Obermeier, R. Daneman, and R.M. Ransohoff Development, maintenance and disruption of the blood-brain barrier Nat. Med. 19 2013 1584 1596
-
(2013)
Nat. Med.
, vol.19
, pp. 1584-1596
-
-
Obermeier, B.1
Daneman, R.2
Ransohoff, R.M.3
-
72
-
-
84937121327
-
Blood-brain barrier endogenous transporters as therapeutic targets: A new model for small molecule CNS drug discovery
-
W.M. Pardridge Blood-brain barrier endogenous transporters as therapeutic targets: a new model for small molecule CNS drug discovery Expert Opin. Ther. Targets 19 2015 1059 1072
-
(2015)
Expert Opin. Ther. Targets
, vol.19
, pp. 1059-1072
-
-
Pardridge, W.M.1
-
73
-
-
84897562702
-
Genetics of PICALM expression and Alzheimer's disease
-
I. Parikh, D.W. Fardo, and S. Estus Genetics of PICALM expression and Alzheimer's disease PLoS ONE 9 2014 e91242
-
(2014)
PLoS ONE
, vol.9
-
-
Parikh, I.1
Fardo, D.W.2
Estus, S.3
-
74
-
-
33749860102
-
Bidirectional control of CNS capillary diameter by pericytes
-
C.M. Peppiatt, C. Howarth, P. Mobbs, and D. Attwell Bidirectional control of CNS capillary diameter by pericytes Nature 443 2006 700 704
-
(2006)
Nature
, vol.443
, pp. 700-704
-
-
Peppiatt, C.M.1
Howarth, C.2
Mobbs, P.3
Attwell, D.4
-
75
-
-
80052933197
-
Basic and therapeutic aspects of angiogenesis
-
M. Potente, H. Gerhardt, and P. Carmeliet Basic and therapeutic aspects of angiogenesis Cell 146 2011 873 887
-
(2011)
Cell
, vol.146
, pp. 873-887
-
-
Potente, M.1
Gerhardt, H.2
Carmeliet, P.3
-
77
-
-
84883168593
-
Increased iron levels and decreased tissue integrity in hippocampus of Alzheimer's disease detected in vivo with magnetic resonance imaging
-
E.P. Raven, P.H. Lu, T.A. Tishler, P. Heydari, and G. Bartzokis Increased iron levels and decreased tissue integrity in hippocampus of Alzheimer's disease detected in vivo with magnetic resonance imaging J. Alzheimers Dis. 37 2013 127 136
-
(2013)
J. Alzheimers Dis.
, vol.37
, pp. 127-136
-
-
Raven, E.P.1
Lu, P.H.2
Tishler, T.A.3
Heydari, P.4
Bartzokis, G.5
-
78
-
-
34948888151
-
Clearance of amyloid-beta by circulating lipoprotein receptors
-
A. Sagare, R. Deane, R.D. Bell, B. Johnson, K. Hamm, R. Pendu, A. Marky, P.J. Lenting, Z. Wu, T. Zarcone, and et al. Clearance of amyloid-beta by circulating lipoprotein receptors Nat. Med. 13 2007 1029 1031
-
(2007)
Nat. Med.
, vol.13
, pp. 1029-1031
-
-
Sagare, A.1
Deane, R.2
Bell, R.D.3
Johnson, B.4
Hamm, K.5
Pendu, R.6
Marky, A.7
Lenting, P.J.8
Wu, Z.9
Zarcone, T.10
-
79
-
-
84890576583
-
Pericyte loss influences Alzheimer-like neurodegeneration in mice
-
A.P. Sagare, R.D. Bell, Z. Zhao, Q. Ma, E.A. Winkler, A. Ramanathan, and B.V. Zlokovic Pericyte loss influences Alzheimer-like neurodegeneration in mice Nat. Commun. 4 2013 2932
-
(2013)
Nat. Commun.
, vol.4
, pp. 2932
-
-
Sagare, A.P.1
Bell, R.D.2
Zhao, Z.3
Ma, Q.4
Winkler, E.A.5
Ramanathan, A.6
Zlokovic, B.V.7
-
80
-
-
84942198698
-
Variable expression of microglial DAP12 and TREM2 genes in Nasu-Hakola disease
-
A. Sasaki, A. Kakita, K. Yoshida, T. Konno, T. Ikeuchi, S. Hayashi, H. Matsuo, and K. Shioda Variable expression of microglial DAP12 and TREM2 genes in Nasu-Hakola disease Neurogenetics 16 2015 265 276
-
(2015)
Neurogenetics
, vol.16
, pp. 265-276
-
-
Sasaki, A.1
Kakita, A.2
Yoshida, K.3
Konno, T.4
Ikeuchi, T.5
Hayashi, S.6
Matsuo, H.7
Shioda, K.8
-
81
-
-
84875191169
-
Transporters of the blood-brain and blood-CSF interfaces in development and in the adult
-
N.R. Saunders, R. Daneman, K.M. Dziegielewska, and S.A. Liddelow Transporters of the blood-brain and blood-CSF interfaces in development and in the adult Mol. Aspects Med. 34 2013 742 752
-
(2013)
Mol. Aspects Med.
, vol.34
, pp. 742-752
-
-
Saunders, N.R.1
Daneman, R.2
Dziegielewska, K.M.3
Liddelow, S.A.4
-
82
-
-
84876288324
-
Deficiency in mural vascular cells coincides with blood-brain barrier disruption in Alzheimer's disease
-
J.D. Sengillo, E.A. Winkler, C.T. Walker, J.S. Sullivan, M. Johnson, and B.V. Zlokovic Deficiency in mural vascular cells coincides with blood-brain barrier disruption in Alzheimer's disease Brain Pathol. 23 2013 303 310
-
(2013)
Brain Pathol.
, vol.23
, pp. 303-310
-
-
Sengillo, J.D.1
Winkler, E.A.2
Walker, C.T.3
Sullivan, J.S.4
Johnson, M.5
Zlokovic, B.V.6
-
83
-
-
84924296638
-
Vascular contributions to cognitive impairment and dementia including Alzheimer's disease
-
H.M. Snyder, R.A. Corriveau, S. Craft, J.E. Faber, S.M. Greenberg, D. Knopman, B.T. Lamb, T.J. Montine, M. Nedergaard, C.B. Schaffer, and et al. Vascular contributions to cognitive impairment and dementia including Alzheimer's disease Alzheimers Dement. 11 2015 710 717
-
(2015)
Alzheimers Dement.
, vol.11
, pp. 710-717
-
-
Snyder, H.M.1
Corriveau, R.A.2
Craft, S.3
Faber, J.E.4
Greenberg, S.M.5
Knopman, D.6
Lamb, B.T.7
Montine, T.J.8
Nedergaard, M.9
Schaffer, C.B.10
-
84
-
-
84928122606
-
Astrocyte barriers to neurotoxic inflammation
-
M.V. Sofroniew Astrocyte barriers to neurotoxic inflammation Nat. Rev. Neurosci. 16 2015 249 263
-
(2015)
Nat. Rev. Neurosci.
, vol.16
, pp. 249-263
-
-
Sofroniew, M.V.1
-
85
-
-
56749104928
-
Canonical Wnt signaling regulates organ-specific assembly and differentiation of CNS vasculature
-
J.M. Stenman, J. Rajagopal, T.J. Carroll, M. Ishibashi, J. McMahon, and A.P. McMahon Canonical Wnt signaling regulates organ-specific assembly and differentiation of CNS vasculature Science 322 2008 1247 1250
-
(2008)
Science
, vol.322
, pp. 1247-1250
-
-
Stenman, J.M.1
Rajagopal, J.2
Carroll, T.J.3
Ishibashi, M.4
McMahon, J.5
McMahon, A.P.6
-
86
-
-
84934444613
-
Cerebrospinal fluid biomarkers of neurovascular dysfunction in mild dementia and Alzheimer's disease
-
M.D. Sweeney, A.P. Sagare, and B.V. Zlokovic Cerebrospinal fluid biomarkers of neurovascular dysfunction in mild dementia and Alzheimer's disease J. Cereb. Blood Flow Metab. 35 2015 1055 1068
-
(2015)
J. Cereb. Blood Flow Metab.
, vol.35
, pp. 1055-1068
-
-
Sweeney, M.D.1
Sagare, A.P.2
Zlokovic, B.V.3
-
87
-
-
2342419356
-
Additive effects of PDGF receptor beta signaling pathways in vascular smooth muscle cell development
-
M.D. Tallquist, W.J. French, and P. Soriano Additive effects of PDGF receptor beta signaling pathways in vascular smooth muscle cell development PLoS Biol. 1 2003 E52
-
(2003)
PLoS Biol.
, vol.1
, pp. E52
-
-
Tallquist, M.D.1
French, W.J.2
Soriano, P.3
-
88
-
-
84856978029
-
Death receptors DR6 and TROY regulate brain vascular development
-
S.J. Tam, D.L. Richmond, J.S. Kaminker, Z. Modrusan, B. Martin-McNulty, T.C. Cao, R.M. Weimer, R.A.D. Carano, N. van Bruggen, and R.J. Watts Death receptors DR6 and TROY regulate brain vascular development Dev. Cell 22 2012 403 417
-
(2012)
Dev. Cell
, vol.22
, pp. 403-417
-
-
Tam, S.J.1
Richmond, D.L.2
Kaminker, J.S.3
Modrusan, Z.4
Martin-McNulty, B.5
Cao, T.C.6
Weimer, R.M.7
Carano, R.A.D.8
Van Bruggen, N.9
Watts, R.J.10
-
89
-
-
84938949776
-
Clearance systems in the brain-implications for Alzheimer disease
-
J.M. Tarasoff-Conway, R.O. Carare, R.S. Osorio, L. Glodzik, T. Butler, E. Fieremans, L. Axel, H. Rusinek, C. Nicholson, B.V. Zlokovic, and et al. Clearance systems in the brain-implications for Alzheimer disease Nat. Rev. Neurol. 11 2015 457 470
-
(2015)
Nat. Rev. Neurol.
, vol.11
, pp. 457-470
-
-
Tarasoff-Conway, J.M.1
Carare, R.O.2
Osorio, R.S.3
Glodzik, L.4
Butler, T.5
Fieremans, E.6
Axel, L.7
Rusinek, H.8
Nicholson, C.9
Zlokovic, B.V.10
-
90
-
-
84943255434
-
Brain barriers: Crosstalk between complex tight junctions and adherens junctions
-
S. Tietz, and B. Engelhardt Brain barriers: Crosstalk between complex tight junctions and adherens junctions J. Cell Biol. 209 2015 493 506
-
(2015)
J. Cell Biol.
, vol.209
, pp. 493-506
-
-
Tietz, S.1
Engelhardt, B.2
-
91
-
-
82755197062
-
Functional links between Aβ toxicity, endocytic trafficking, and Alzheimer's disease risk factors in yeast
-
S. Treusch, S. Hamamichi, J.L. Goodman, K.E.S. Matlack, C.Y. Chung, V. Baru, J.M. Shulman, A. Parrado, B.J. Bevis, J.S. Valastyan, and et al. Functional links between Aβ toxicity, endocytic trafficking, and Alzheimer's disease risk factors in yeast Science 334 2011 1241 1245
-
(2011)
Science
, vol.334
, pp. 1241-1245
-
-
Treusch, S.1
Hamamichi, S.2
Goodman, J.L.3
Matlack, K.E.S.4
Chung, C.Y.5
Baru, V.6
Shulman, J.M.7
Parrado, A.8
Bevis, B.J.9
Valastyan, J.S.10
-
92
-
-
84864021984
-
Regional astrocyte allocation regulates CNS synaptogenesis and repair
-
H.-H. Tsai, H. Li, L.C. Fuentealba, A.V. Molofsky, R. Taveira-Marques, H. Zhuang, A. Tenney, A.T. Murnen, S.P.J. Fancy, F. Merkle, and et al. Regional astrocyte allocation regulates CNS synaptogenesis and repair Science 337 2012 358 362
-
(2012)
Science
, vol.337
, pp. 358-362
-
-
Tsai, H.-H.1
Li, H.2
Fuentealba, L.C.3
Molofsky, A.V.4
Taveira-Marques, R.5
Zhuang, H.6
Tenney, A.7
Murnen, A.T.8
Fancy, S.P.J.9
Merkle, F.10
-
93
-
-
0033850218
-
Mutational analysis of GLUT1 (SLC2A1) in Glut-1 deficiency syndrome
-
D. Wang, P. Kranz-Eble, and D.C. De Vivo Mutational analysis of GLUT1 (SLC2A1) in Glut-1 deficiency syndrome Hum. Mutat. 16 2000 224 231
-
(2000)
Hum. Mutat.
, vol.16
, pp. 224-231
-
-
Wang, D.1
Kranz-Eble, P.2
De Vivo, D.C.3
-
94
-
-
84862798098
-
Mutations in SLC20A2 link familial idiopathic basal ganglia calcification with phosphate homeostasis
-
C. Wang, Y. Li, L. Shi, J. Ren, M. Patti, T. Wang, J.R.M. de Oliveira, M.-J. Sobrido, B. Quintáns, M. Baquero, and et al. Mutations in SLC20A2 link familial idiopathic basal ganglia calcification with phosphate homeostasis Nat. Genet. 44 2012 254 256
-
(2012)
Nat. Genet.
, vol.44
, pp. 254-256
-
-
Wang, C.1
Li, Y.2
Shi, L.3
Ren, J.4
Patti, M.5
Wang, T.6
De Oliveira, J.R.M.7
Sobrido, M.-J.8
Quintáns, B.9
Baquero, M.10
-
95
-
-
84870897220
-
Norrin/Frizzled4 signaling in retinal vascular development and blood brain barrier plasticity
-
Y. Wang, A. Rattner, Y. Zhou, J. Williams, P.M. Smallwood, and J. Nathans Norrin/Frizzled4 signaling in retinal vascular development and blood brain barrier plasticity Cell 151 2012 1332 1344
-
(2012)
Cell
, vol.151
, pp. 1332-1344
-
-
Wang, Y.1
Rattner, A.2
Zhou, Y.3
Williams, J.4
Smallwood, P.M.5
Nathans, J.6
-
96
-
-
80055014830
-
Central nervous system pericytes in health and disease
-
E.A. Winkler, R.D. Bell, and B.V. Zlokovic Central nervous system pericytes in health and disease Nat. Neurosci. 14 2011 1398 1405
-
(2011)
Nat. Neurosci.
, vol.14
, pp. 1398-1405
-
-
Winkler, E.A.1
Bell, R.D.2
Zlokovic, B.V.3
-
97
-
-
84872363503
-
Blood-spinal cord barrier breakdown and pericyte reductions in amyotrophic lateral sclerosis
-
E.A. Winkler, J.D. Sengillo, J.S. Sullivan, J.S. Henkel, S.H. Appel, and B.V. Zlokovic Blood-spinal cord barrier breakdown and pericyte reductions in amyotrophic lateral sclerosis Acta Neuropathol. 125 2013 111 120
-
(2013)
Acta Neuropathol.
, vol.125
, pp. 111-120
-
-
Winkler, E.A.1
Sengillo, J.D.2
Sullivan, J.S.3
Henkel, J.S.4
Appel, S.H.5
Zlokovic, B.V.6
-
98
-
-
84925594369
-
GLUT1 reductions exacerbate Alzheimer's disease vasculo-neuronal dysfunction and degeneration
-
E.A. Winkler, Y. Nishida, A.P. Sagare, S.V. Rege, R.D. Bell, D. Perlmutter, J.D. Sengillo, S. Hillman, P. Kong, A.R. Nelson, and et al. GLUT1 reductions exacerbate Alzheimer's disease vasculo-neuronal dysfunction and degeneration Nat. Neurosci. 18 2015 521 530
-
(2015)
Nat. Neurosci.
, vol.18
, pp. 521-530
-
-
Winkler, E.A.1
Nishida, Y.2
Sagare, A.P.3
Rege, S.V.4
Bell, R.D.5
Perlmutter, D.6
Sengillo, J.D.7
Hillman, S.8
Kong, P.9
Nelson, A.R.10
-
99
-
-
80052026271
-
The junctional adhesion molecule JAM-C regulates polarized transendothelial migration of neutrophils in vivo
-
A. Woodfin, M.-B. Voisin, M. Beyrau, B. Colom, D. Caille, F.-M. Diapouli, G.B. Nash, T. Chavakis, S.M. Albelda, G.E. Rainger, and et al. The junctional adhesion molecule JAM-C regulates polarized transendothelial migration of neutrophils in vivo Nat. Immunol. 12 2011 761 769
-
(2011)
Nat. Immunol.
, vol.12
, pp. 761-769
-
-
Woodfin, A.1
Voisin, M.-B.2
Beyrau, M.3
Colom, B.4
Caille, D.5
Diapouli, F.-M.6
Nash, G.B.7
Chavakis, T.8
Albelda, S.M.9
Rainger, G.E.10
-
100
-
-
84924388118
-
Integrin β1 controls VE-cadherin localization and blood vessel stability
-
H. Yamamoto, M. Ehling, K. Kato, K. Kanai, M. van Lessen, M. Frye, D. Zeuschner, M. Nakayama, D. Vestweber, and R.H. Adams Integrin β1 controls VE-cadherin localization and blood vessel stability Nat. Commun. 6 2015 6429
-
(2015)
Nat. Commun.
, vol.6
, pp. 6429
-
-
Yamamoto, H.1
Ehling, M.2
Kato, K.3
Kanai, K.4
Van Lessen, M.5
Frye, M.6
Zeuschner, D.7
Nakayama, M.8
Vestweber, D.9
Adams, R.H.10
-
101
-
-
84928893681
-
Astrocytic laminin regulates pericyte differentiation and maintains blood brain barrier integrity
-
Y. Yao, Z.-L. Chen, E.H. Norris, and S. Strickland Astrocytic laminin regulates pericyte differentiation and maintains blood brain barrier integrity Nat. Commun. 5 2014 3413
-
(2014)
Nat. Commun.
, vol.5
, pp. 3413
-
-
Yao, Y.1
Chen, Z.-L.2
Norris, E.H.3
Strickland, S.4
-
102
-
-
84902167026
-
Incidence of cerebral microbleeds in preclinical Alzheimer disease
-
P.A. Yates, P.M. Desmond, P.M. Phal, C. Steward, C. Szoeke, O. Salvado, K.A. Ellis, R.N. Martins, C.L. Masters, D. Ames, et al. AIBL Research Group Incidence of cerebral microbleeds in preclinical Alzheimer disease Neurology 82 2014 1266 1273
-
(2014)
Neurology
, vol.82
, pp. 1266-1273
-
-
Yates, P.A.1
Desmond, P.M.2
Phal, P.M.3
Steward, C.4
Szoeke, C.5
Salvado, O.6
Ellis, K.A.7
Martins, R.N.8
Masters, C.L.9
Ames, D.10
-
103
-
-
84900992748
-
Blood-brain barrier: A dual life of MFSD2A?
-
Z. Zhao, and B.V. Zlokovic Blood-brain barrier: a dual life of MFSD2A? Neuron 82 2014 728 730
-
(2014)
Neuron
, vol.82
, pp. 728-730
-
-
Zhao, Z.1
Zlokovic, B.V.2
-
104
-
-
84933277693
-
Central role for PICALM in amyloid-β blood-brain barrier transcytosis and clearance
-
Z. Zhao, A.P. Sagare, Q. Ma, M.R. Halliday, P. Kong, K. Kisler, E.A. Winkler, A. Ramanathan, T. Kanekiyo, G. Bu, and et al. Central role for PICALM in amyloid-β blood-brain barrier transcytosis and clearance Nat. Neurosci. 18 2015 978 987
-
(2015)
Nat. Neurosci.
, vol.18
, pp. 978-987
-
-
Zhao, Z.1
Sagare, A.P.2
Ma, Q.3
Halliday, M.R.4
Kong, P.5
Kisler, K.6
Winkler, E.A.7
Ramanathan, A.8
Kanekiyo, T.9
Bu, G.10
-
105
-
-
84908481545
-
Gpr124 controls CNS angiogenesis and blood-brain barrier integrity by promoting ligand-specific canonical wnt signaling
-
Y. Zhou, and J. Nathans Gpr124 controls CNS angiogenesis and blood-brain barrier integrity by promoting ligand-specific canonical wnt signaling Dev. Cell 31 2014 248 256
-
(2014)
Dev. Cell
, vol.31
, pp. 248-256
-
-
Zhou, Y.1
Nathans, J.2
-
106
-
-
84907008498
-
Canonical WNT signaling components in vascular development and barrier formation
-
Y. Zhou, Y. Wang, M. Tischfield, J. Williams, P.M. Smallwood, A. Rattner, M.M. Taketo, and J. Nathans Canonical WNT signaling components in vascular development and barrier formation J. Clin. Invest. 124 2014 3825 3846
-
(2014)
J. Clin. Invest.
, vol.124
, pp. 3825-3846
-
-
Zhou, Y.1
Wang, Y.2
Tischfield, M.3
Williams, J.4
Smallwood, P.M.5
Rattner, A.6
Taketo, M.M.7
Nathans, J.8
-
107
-
-
34247343262
-
Microvascular injury and blood-brain barrier leakage in Alzheimer's disease
-
B.D. Zipser, C.E. Johanson, L. Gonzalez, T.M. Berzin, R. Tavares, C.M. Hulette, M.P. Vitek, V. Hovanesian, and E.G. Stopa Microvascular injury and blood-brain barrier leakage in Alzheimer's disease Neurobiol. Aging 28 2007 977 986
-
(2007)
Neurobiol. Aging
, vol.28
, pp. 977-986
-
-
Zipser, B.D.1
Johanson, C.E.2
Gonzalez, L.3
Berzin, T.M.4
Tavares, R.5
Hulette, C.M.6
Vitek, M.P.7
Hovanesian, V.8
Stopa, E.G.9
-
108
-
-
0028806803
-
Cerebrovascular permeability to peptides: Manipulations of transport systems at the blood-brain barrier
-
B.V. Zlokovic Cerebrovascular permeability to peptides: manipulations of transport systems at the blood-brain barrier Pharm. Res. 12 1995 1395 1406
-
(1995)
Pharm. Res.
, vol.12
, pp. 1395-1406
-
-
Zlokovic, B.V.1
-
109
-
-
38149090292
-
The blood-brain barrier in health and chronic neurodegenerative disorders
-
B.V. Zlokovic The blood-brain barrier in health and chronic neurodegenerative disorders Neuron 57 2008 178 201
-
(2008)
Neuron
, vol.57
, pp. 178-201
-
-
Zlokovic, B.V.1
-
110
-
-
81555200043
-
Neurovascular pathways to neurodegeneration in Alzheimer's disease and other disorders
-
B.V. Zlokovic Neurovascular pathways to neurodegeneration in Alzheimer's disease and other disorders Nat. Rev. Neurosci. 12 2011 723 738
-
(2011)
Nat. Rev. Neurosci.
, vol.12
, pp. 723-738
-
-
Zlokovic, B.V.1
-
111
-
-
84876136764
-
Cerebrovascular effects of apolipoprotein E: Implications for Alzheimer disease
-
B.V. Zlokovic Cerebrovascular effects of apolipoprotein E: implications for Alzheimer disease JAMA Neurol. 70 2013 440 444
-
(2013)
JAMA Neurol.
, vol.70
, pp. 440-444
-
-
Zlokovic, B.V.1
-
112
-
-
0022257648
-
Blood-brain barrier permeability to leucine-enkephalin, D-alanine2-D-leucine5-enkephalin and their N-terminal amino acid (tyrosine)
-
B.V. Zlokovic, D.J. Begley, and D.G. Chain-Eliash Blood-brain barrier permeability to leucine-enkephalin, D-alanine2-D-leucine5-enkephalin and their N-terminal amino acid (tyrosine) Brain Res. 336 1985 125 132
-
(1985)
Brain Res.
, vol.336
, pp. 125-132
-
-
Zlokovic, B.V.1
Begley, D.J.2
Chain-Eliash, D.G.3
-
113
-
-
78149255128
-
Low-density lipoprotein receptor-related protein-1: A serial clearance homeostatic mechanism controlling Alzheimer's amyloid β-peptide elimination from the brain
-
B.V. Zlokovic, R. Deane, A.P. Sagare, R.D. Bell, and E.A. Winkler Low-density lipoprotein receptor-related protein-1: a serial clearance homeostatic mechanism controlling Alzheimer's amyloid β-peptide elimination from the brain J. Neurochem. 115 2010 1077 1089
-
(2010)
J. Neurochem.
, vol.115
, pp. 1077-1089
-
-
Zlokovic, B.V.1
Deane, R.2
Sagare, A.P.3
Bell, R.D.4
Winkler, E.A.5
-
114
-
-
84895830747
-
Prevalence of cortical superficial siderosis in a memory clinic population
-
H.I. Zonneveld, J.D.C. Goos, M.P. Wattjes, N.D. Prins, P. Scheltens, W.M. van der Flier, J.P.A. Kuijer, M. Muller, and F. Barkhof Prevalence of cortical superficial siderosis in a memory clinic population Neurology 82 2014 698 704
-
(2014)
Neurology
, vol.82
, pp. 698-704
-
-
Zonneveld, H.I.1
Goos, J.D.C.2
Wattjes, M.P.3
Prins, N.D.4
Scheltens, P.5
Van Der Flier, W.M.6
Kuijer, J.P.A.7
Muller, M.8
Barkhof, F.9
|