The Limitations of in Vitro Experimentation in Understanding Biofilms and Chronic Infection

Journal of Molecular Biology

Volumn 427, Issue 23, 2015, Pages 3646-3661

  Roberts, Aled E L ^a   Kragh, Kasper N ^b   Bjarnsholt, Thomas ^b   Diggle, Stephen P ^a  

^a UNIVERSITY OF NOTTINGHAM   (United Kingdom)

^b UNIVERSITY OF COPENHAGEN   (Denmark)

Author keywords

Abbreviations CF cystic fibrosis; AMR antimicrobial resistance; CDC Center for Disease Control; CLSM confocal laser scanning microscopy; MIC minimal inhibitory concentrations; PMN polymorphonuclear leukocyte; QS quorum sensing; SCFM synthetic CF sputum medium

Indexed keywords

ANTIBIOTIC AGENT;

ANTIBIOTIC RESISTANCE; ANTIBIOTIC THERAPY; BACTERIAL CELL; BACTERIAL INFECTION; BIOFILM; BURKHOLDERIA CENOCEPACIA; CANDIDA ALBICANS; CONFOCAL LASER MICROSCOPY; EXTRACELLULAR MATRIX; GENE EXPRESSION; HAEMOPHILUS INFLUENZAE; IMMUNE RESPONSE; IN VITRO STUDY; IN VIVO STUDY; MINIMUM INHIBITORY CONCENTRATION; MORAXELLA CATARRHALIS; NEUTROPHIL; NONHUMAN; OTITIS MEDIA; PRIORITY JOURNAL; PSEUDOMONAS AERUGINOSA; REVIEW; ANIMAL; CHRONIC DISEASE; DISEASE MODEL; HUMAN; MICROBIOLOGICAL EXAMINATION; MICROBIOLOGY; PATHOGENICITY; PROCEDURES; PSEUDOMONAS INFECTION;

ANIMALS; BACTERIAL INFECTIONS; BACTERIOLOGICAL TECHNIQUES; BIOFILMS; CHRONIC DISEASE; DISEASE MODELS, ANIMAL; HUMANS; IN VITRO TECHNIQUES; PSEUDOMONAS AERUGINOSA; PSEUDOMONAS INFECTIONS;

EID: 84947869938     PISSN: 00222836     EISSN: 10898638     Source Type: Journal    
DOI: 10.1016/j.jmb.2015.09.002     Document Type: Review

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