Pseudomonas aeruginosa adaptation in the nasopharyngeal reservoir leads to migration and persistence in the lungs

Nature Communications

Volumn 5, Issue , 2014, Pages

  Fothergill, Joanne L ^a   Neill, Daniel R ^a   Loman, Nick ^b   Winstanley, Craig ^a   Kadioglu, Aras ^a  

^a UNIVERSITY OF LIVERPOOL   (United Kingdom)

^b UNIVERSITY OF BIRMINGHAM   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

CIPROFLOXACIN; TOBRAMYCIN; ANTIINFECTIVE AGENT; BACTERIAL PROTEIN;

ANTIBIOTIC RESISTANCE; COLONIZATION; GENOTYPE; IMMUNE SYSTEM; INFECTIOUS DISEASE; MICROBIAL COMMUNITY; NICHE; RODENT;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIBIOTIC RESISTANCE; ARTICLE; BACTERIAL GENOME; BIOFILM; DISEASE CARRIER; GENE EXPRESSION; GENOTYPE; IN VITRO STUDY; IN VIVO STUDY; INOCULATION; LUNG INFECTION; MOUSE; NASOPHARYNX; NONHUMAN; PHENOTYPE; PSEUDOMONAS AERUGINOSA; PSEUDOMONAS INFECTION; SINGLE NUCLEOTIDE POLYMORPHISM; UPPER RESPIRATORY TRACT; ADAPTATION; AMINO ACID SEQUENCE; ANIMAL; BACTERIAL COUNT; BAGG ALBINO MOUSE; DISEASE MODEL; DRUG EFFECTS; FEMALE; GENE EXPRESSION REGULATION; GENETICS; GROWTH, DEVELOPMENT AND AGING; HOST PATHOGEN INTERACTION; HUMAN; INHALATIONAL DRUG ADMINISTRATION; INTRANASAL DRUG ADMINISTRATION; LUNG; METABOLISM; MICROBIOLOGY; MOLECULAR GENETICS; NUCLEOTIDE SEQUENCE; PARANASAL SINUS; PATHOGENICITY; PATHOLOGY; PSEUDOMONAS INFECTIONS;

ADAPTATION, PHYSIOLOGICAL; ADMINISTRATION, INHALATION; ADMINISTRATION, INTRANASAL; AMINO ACID SEQUENCE; ANIMALS; ANTI-BACTERIAL AGENTS; BACTERIAL PROTEINS; BASE SEQUENCE; BIOFILMS; COLONY COUNT, MICROBIAL; DISEASE MODELS, ANIMAL; FEMALE; GENE EXPRESSION REGULATION, BACTERIAL; GENOTYPE; HOST-PATHOGEN INTERACTIONS; HUMANS; LUNG; MICE; MICE, INBRED BALB C; MOLECULAR SEQUENCE DATA; NASOPHARYNX; PARANASAL SINUSES; PHENOTYPE; POLYMORPHISM, SINGLE NUCLEOTIDE; PSEUDOMONAS AERUGINOSA; PSEUDOMONAS INFECTIONS;

EID: 84907351159     PISSN: None     EISSN: 20411723     Source Type: Journal    
DOI: 10.1038/ncomms5780     Document Type: Article

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