메뉴 건너뛰기




Volumn 21, Issue 28, 2015, Pages 4000-4006

Emerging pharmacological treatments to prevent abdominal aortic aneurysm growth and rupture

Author keywords

Abdominal aortic aneurysm; Interleukin 1 ; Renin angiotensin system; Statins; Tetracyclines

Indexed keywords

ANGIOGENESIS INHIBITOR; ANGIOTENSIN CONVERTING ENZYME 2; ANGIOTENSIN[1-7]; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE INHIBITOR; INTERLEUKIN 1; INTERLEUKIN 1BETA; RENIN INHIBITOR; TETRACYCLINE DERIVATIVE; UROCORTIN II;

EID: 84947748834     PISSN: 13816128     EISSN: 18734286     Source Type: Journal    
DOI: 10.2174/1381612821666150826095346     Document Type: Review
Times cited : (14)

References (105)
  • 1
    • 79952848987 scopus 로고    scopus 로고
    • Novel aspects of the pathogenesis of aneurysms of the abdominal aorta in humans
    • Michel JB, Martin-Ventura JL, Egido J, et al. Novel aspects of the pathogenesis of aneurysms of the abdominal aorta in humans. Cardiovasc Res 2011; 90(1): 18-27.
    • (2011) Cardiovasc Res , vol.90 , Issue.1 , pp. 18-27
    • Michel, J.B.1    Martin-Ventura, J.L.2    Egido, J.3
  • 2
    • 18144368061 scopus 로고    scopus 로고
    • Defawe, Abdominal aortic aneurysm
    • Sakalihasan NR, Limet OD. Defawe, Abdominal aortic aneurysm. Lancet 2005; 365(9470): 1577-89.
    • (2005) Lancet , vol.365 , Issue.9470 , pp. 1577-1589
    • Sakalihasan, N.R.1    Limet, O.D.2
  • 3
    • 0036733629 scopus 로고    scopus 로고
    • Matrix metalloproteinases 2 and 9 work in concert to produce aortic aneurysms
    • Longo GM, Xiong W, Greiner TC, Zhao Y, Fiotti N, Baxter BT. Matrix metalloproteinases 2 and 9 work in concert to produce aortic aneurysms. J Clin Invest 2002; 110(5): 625-32.
    • (2002) J Clin Invest , vol.110 , Issue.5 , pp. 625-632
    • Longo, G.M.1    Xiong, W.2    Greiner, T.C.3    Zhao, Y.4    Fiotti, N.5    Baxter, B.T.6
  • 4
    • 0031446107 scopus 로고    scopus 로고
    • Vascular smooth muscle cell apoptosis in abdominal aortic aneurysms
    • Thompson RW, Liao S, Curci JA. Vascular smooth muscle cell apoptosis in abdominal aortic aneurysms. Coron Artery Dis 1997; 8(10): 623-31.
    • (1997) Coron Artery Dis , vol.8 , Issue.10 , pp. 623-631
    • Thompson, R.W.1    Liao, S.2    Curci, J.A.3
  • 6
    • 0037046644 scopus 로고    scopus 로고
    • Immediate repair compared with surveillance of small abdominal aortic aneurysms
    • Lederle FA, Wilson SE, Johnson GR. Immediate repair compared with surveillance of small abdominal aortic aneurysms. N Engl J Med 2002; 346(19): 1437-44.
    • (2002) N Engl J Med , vol.346 , Issue.19 , pp. 1437-1444
    • Lederle, F.A.1    Wilson, S.E.2    Johnson, G.R.3
  • 7
    • 41949095013 scopus 로고    scopus 로고
    • Medical management of small abdominal aortic aneurysms
    • Baxter BT, MC. Terrin, RL. Dalman, Medical management of small abdominal aortic aneurysms. Circulation 2008; 117(14): 1883-9.
    • (2008) Circulation , vol.117 , Issue.14 , pp. 1883-1889
    • Baxter, B.T.1    Terrin, M.C.2    Dalman, R.L.3
  • 8
    • 84888270403 scopus 로고    scopus 로고
    • Current status of medical treatment for abdominal aortic aneurysm
    • Kurosawa K, JS. Matsumura, D. Yamanouchi, Current status of medical treatment for abdominal aortic aneurysm. Circ J 2013; 77(12): 2860-6.
    • (2013) Circ J , vol.77 , Issue.12 , pp. 2860-2866
    • Kurosawa, K.1    Matsumura, J.S.2    Yamanouchi, D.3
  • 9
    • 36549034768 scopus 로고    scopus 로고
    • Blood cholesterol and vascular mortality by age, sex, blood pressure: A meta-analysis of individual data from 61 prospective studies with 55,000 vascular deaths
    • Prospective Studies Collaboration1, Lewington S, Whitlock G, et al. Blood cholesterol and vascular mortality by age, sex, blood pressure: a meta-analysis of individual data from 61 prospective studies with 55,000 vascular deaths. Lancet 2007; 370(9602): 1829- 39.
    • (2007) Lancet , vol.370 , Issue.9602 , pp. 1829-1839
    • Lewington, S.1    Whitlock, G.2
  • 10
    • 0035989581 scopus 로고    scopus 로고
    • Abdominal aortic aneurysms: Fresh insights from a novel animal model of the disease
    • Manning MW, Cassi LA, Huang J, Szilvassy SJ, Daugherty A. Abdominal aortic aneurysms: fresh insights from a novel animal model of the disease. Vasc Med 2002; 7(1): 45-54.
    • (2002) Vasc Med , vol.7 , Issue.1 , pp. 45-54
    • Manning, M.W.1    Cassi, L.A.2    Huang, J.3    Szilvassy, S.J.4    Daugherty, A.5
  • 11
    • 77958541531 scopus 로고    scopus 로고
    • The pleiotropic effects of the hydroxy-methyl-glutaryl-CoA reductase inhibitors in cardiovascular disease: A comprehensive review
    • Mihos CG, Salas MJ, Santana O. The pleiotropic effects of the hydroxy-methyl-glutaryl-CoA reductase inhibitors in cardiovascular disease: a comprehensive review. Cardiol Rev 2010; 18(6): 298- 304.
    • (2010) Cardiol Rev , vol.18 , Issue.6 , pp. 298-304
    • Mihos, C.G.1    Salas, M.J.2    Santana, O.3
  • 12
    • 11144276528 scopus 로고    scopus 로고
    • Treatment with simvastatin suppresses the development of experimental abdominal aortic aneurysms in normal and hypercholesterolemic mice
    • Steinmetz EF, Buckley C, Shames ML, et al. Treatment with simvastatin suppresses the development of experimental abdominal aortic aneurysms in normal and hypercholesterolemic mice. Ann Surg 2005; 241(1): 92-101.
    • (2005) Ann Surg , vol.241 , Issue.1 , pp. 92-101
    • Steinmetz, E.F.1    Buckley, C.2    Shames, M.L.3
  • 13
    • 84856552165 scopus 로고    scopus 로고
    • Treatment with simvastatin inhibits the formation of abdominal aortic aneurysms in rabbits
    • Mastoraki ST, Toumpoulis IK, Anagnostopoulos CE, et al. Treatment with simvastatin inhibits the formation of abdominal aortic aneurysms in rabbits. Ann Vasc Surg 2012. 26(2): 250-8.
    • (2012) Ann Vasc Surg , vol.26 , Issue.2 , pp. 250-258
    • Mastoraki, S.T.1    Toumpoulis, I.K.2    Anagnostopoulos, C.E.3
  • 14
    • 0036633659 scopus 로고    scopus 로고
    • A 3-hydroxy-3- methylglutaryl coenzyme A reductase inhibitor, cerivastatin, suppresses production of matrix metalloproteinase-9 in human abdominal aortic aneurysm wall
    • Nagashima H, Aoka Y, Sakomura Y, et al, A 3-hydroxy-3- methylglutaryl coenzyme A reductase inhibitor, cerivastatin, suppresses production of matrix metalloproteinase-9 in human abdominal aortic aneurysm wall. J Vasc Surg 2002; 36(1): 158-63.
    • (2002) J Vasc Surg , vol.36 , Issue.1 , pp. 158-163
    • Nagashima, H.1    Aoka, Y.2    Sakomura, Y.3
  • 15
    • 34547588531 scopus 로고    scopus 로고
    • Simvastatin attenuates the activity of matrix metalloprotease-9 in aneurysmal aortic tissue
    • Evans J, Powell JT, Schwalbe E, Loftus IM, Thompson MM. Simvastatin attenuates the activity of matrix metalloprotease-9 in aneurysmal aortic tissue. Eur J Vasc Endovasc Surg 2007; 34(3): 302-3.
    • (2007) Eur J Vasc Endovasc Surg , vol.34 , Issue.3 , pp. 302-303
    • Evans, J.1    Powell, J.T.2    Schwalbe, E.3    Loftus, I.M.4    Thompson, M.M.5
  • 16
    • 33744902627 scopus 로고    scopus 로고
    • Statins are associated with a reduced infrarenal abdominal aortic aneurysm growth
    • Schouten O, van Laanen JH, Boersma E, et al. Statins are associated with a reduced infrarenal abdominal aortic aneurysm growth. Eur J Vasc Endovasc Surg 2006; 32(1): 21-6.
    • (2006) Eur J Vasc Endovasc Surg , vol.32 , Issue.1 , pp. 21-26
    • Schouten, O.1    van Laanen, J.H.2    Boersma, E.3
  • 17
    • 44349115500 scopus 로고    scopus 로고
    • Growth predictors and prognosis of small abdominal aortic aneurysms
    • Schlösser FJ, Tangelder MJ, Verhagen HJ, et al. Growth predictors and prognosis of small abdominal aortic aneurysms. J Vasc Surg 2008; 47(6): 1127-33.
    • (2008) J Vasc Surg , vol.47 , Issue.6 , pp. 1127-1133
    • Schlösser, F.J.1    Tangelder, M.J.2    Verhagen, H.J.3
  • 18
    • 31344433148 scopus 로고    scopus 로고
    • Mortality and size of abdominal aortic aneurysm at long-term follow-up of patients not treated surgically and treated with and without statins
    • Sukhija R, Aronow WS, Sandhu R, Kakar P, Babu S. et al, Mortality and size of abdominal aortic aneurysm at long-term follow-up of patients not treated surgically and treated with and without statins. Am J Cardiol 2006; 97(2): 279-80.
    • (2006) Am J Cardiol , vol.97 , Issue.2 , pp. 279-280
    • Sukhija, R.1    Aronow, W.S.2    Sandhu, R.3    Kakar, P.4    Babu, S.5
  • 19
    • 75449095892 scopus 로고    scopus 로고
    • Association of statin prescription with small abdominal aortic aneurysm progression
    • Ferguson CD, Clancy P, Bourke B, et al. Association of statin prescription with small abdominal aortic aneurysm progression. Am Heart J 2010. 159(2): 307-13.
    • (2010) Am Heart J , vol.159 , Issue.2 , pp. 307-313
    • Ferguson, C.D.1    Clancy, P.2    Bourke, B.3
  • 20
    • 84865459649 scopus 로고    scopus 로고
    • Effects of statin therapy on abdominal aortic aneurysm growth: A meta-analysis and metaregression of observational comparative studies
    • Takagi H, Yamamoto H, Iwata K, et al. Effects of statin therapy on abdominal aortic aneurysm growth: a meta-analysis and metaregression of observational comparative studies. Eur J Vasc Endovasc Surg 2012; 44(3): 287-92.
    • (2012) Eur J Vasc Endovasc Surg , vol.44 , Issue.3 , pp. 287-292
    • Takagi, H.1    Yamamoto, H.2    Iwata, K.3
  • 21
    • 79251509569 scopus 로고    scopus 로고
    • Systematic review and meta-analysis of the effects of statin therapy on abdominal aortic aneurysms
    • Twine CP, Williams IM. Systematic review and meta-analysis of the effects of statin therapy on abdominal aortic aneurysms. Br J Surg 2011; 98(3): 346-53.
    • (2011) Br J Surg , vol.98 , Issue.3 , pp. 346-353
    • Twine, C.P.1    Williams, I.M.2
  • 22
    • 84859608366 scopus 로고    scopus 로고
    • Meta-analysis of individual patient data to examine factors affecting growth and rupture of small abdominal aortic aneurysms
    • Sweeting MJ, Thompson SG, Brown LC, et al. Meta-analysis of individual patient data to examine factors affecting growth and rupture of small abdominal aortic aneurysms. Br J Surg 2012; 99(5): 655-65.
    • (2012) Br J Surg , vol.99 , Issue.5 , pp. 655-665
    • Sweeting, M.J.1    Thompson, S.G.2    Brown, L.C.3
  • 23
    • 77949536656 scopus 로고    scopus 로고
    • Tissue renin-angiotensin-aldosterone systems: Targets for pharmacological therapy
    • Bader, M, Tissue renin-angiotensin-aldosterone systems: Targets for pharmacological therapy. Annu Rev Pharmacol Toxicol 2010; 50: 439-65.
    • (2010) Annu Rev Pharmacol Toxicol , vol.50 , pp. 439-465
    • Bader, M.1
  • 24
    • 0030948534 scopus 로고    scopus 로고
    • Biological functions of angiotensin and its receptors
    • Matsusaka T, Ichikawa I. Biological functions of angiotensin and its receptors. Annu Rev Physiol 1997; 59: 395-412.
    • (1997) Annu Rev Physiol , vol.59 , pp. 395-412
    • Matsusaka, T.1    Ichikawa, I.2
  • 25
    • 0033824138 scopus 로고    scopus 로고
    • International union of pharmacology. XXIII. The angiotensin II receptors
    • de Gasparo M, Catt KJ, Inagami T, et al. International union of pharmacology. XXIII. The angiotensin II receptors. Pharmacol Rev 2000; 52(3): 415-72.
    • (2000) Pharmacol Rev , vol.52 , Issue.3 , pp. 415-472
    • de Gasparo, M.1    Catt, K.J.2    Inagami, T.3
  • 26
    • 0034129997 scopus 로고    scopus 로고
    • Angiotensin II promotes atherosclerotic lesions and aneurysms in apolipoprotein E-deficient mice
    • Daugherty A, Manning MW, Cassis LA. Angiotensin II promotes atherosclerotic lesions and aneurysms in apolipoprotein E-deficient mice. J Clin Invest 2000; 105(11): 1605-12.
    • (2000) J Clin Invest , vol.105 , Issue.11 , pp. 1605-1612
    • Daugherty, A.1    Manning, M.W.2    Cassis, L.A.3
  • 27
    • 0032787345 scopus 로고    scopus 로고
    • Chronic angiotensin II infusion promotes atherogenesis in low density lipoprotein receptor -/- mice
    • Daugherty, A. Cassis L. Chronic angiotensin II infusion promotes atherogenesis in low density lipoprotein receptor -/- mice. Ann N Y Acad Sci 1999; 892: 108-18.
    • (1999) Ann N Y Acad Sci , vol.892 , pp. 108-118
    • Daugherty, A.1    Cassis, L.2
  • 28
    • 80054965704 scopus 로고    scopus 로고
    • Complex pathologies of angiotensin II-induced abdominal aortic aneurysms
    • Daugherty, A, L.A. Cassis, H. Lu, Complex pathologies of angiotensin II-induced abdominal aortic aneurysms. J Zhejiang Univ Sci B 2011; 12(8): 624-8.
    • (2011) J Zhejiang Univ Sci B , vol.12 , Issue.8 , pp. 624-628
    • Daugherty, A.1    Cassis, L.A.2    Lu, H.3
  • 29
    • 84922473714 scopus 로고    scopus 로고
    • Dissecting abdominal aortic aneurysm in Ang II-infused mice: Suprarenal branch ruptures and apparent luminal dilatation
    • Trachet B, Fraga-Silva RA, Piersigilli A et al, Dissecting abdominal aortic aneurysm in Ang II-infused mice: suprarenal branch ruptures and apparent luminal dilatation. Cardiovasc Res 2015; 105(2): 213- 22.
    • (2015) Cardiovasc Res , vol.105 , Issue.2 , pp. 213-222
    • Trachet, B.1    Fraga-Silva, R.A.2    Piersigilli, A.3
  • 30
    • 84865247980 scopus 로고    scopus 로고
    • Remodeling of intramural thrombus and collagen in an Ang-II infusion ApoE-/- model of dissecting aortic aneurysms
    • Schriefl AJ, Collins MJ, Pierce DM, et al. Remodeling of intramural thrombus and collagen in an Ang-II infusion ApoE-/- model of dissecting aortic aneurysms. Thromb Res 2012; 130(3): e139-46.
    • (2012) Thromb Res , vol.130 , Issue.3 , pp. e139-e146
    • Schriefl, A.J.1    Collins, M.J.2    Pierce, D.M.3
  • 31
    • 0034749822 scopus 로고    scopus 로고
    • Antagonism of AT2 receptors augments angiotensin II-induced abdominal aortic aneurysms and atherosclerosis
    • Daugherty A, Manning MW, Cassis LA. Antagonism of AT2 receptors augments angiotensin II-induced abdominal aortic aneurysms and atherosclerosis. Br J Pharmacol 2001; 134(4): 865- 70.
    • (2001) Br J Pharmacol , vol.134 , Issue.4 , pp. 865-870
    • Daugherty, A.1    Manning, M.W.2    Cassis, L.A.3
  • 32
    • 70350215665 scopus 로고    scopus 로고
    • Involvement of vascular angiotensin II-forming enzymes in the progression of aortic abdominal aneurysms in angiotensin II- infused ApoE-deficient mice
    • Inoue N, Muramatsu M, Jin D et al, Involvement of vascular angiotensin II-forming enzymes in the progression of aortic abdominal aneurysms in angiotensin II- infused ApoE-deficient mice. J Atheroscler Thromb 2009; 16(3): 164-71.
    • (2009) J Atheroscler Thromb , vol.16 , Issue.3 , pp. 164-171
    • Inoue, N.1    Muramatsu, M.2    Jin, D.3
  • 33
    • 84870700463 scopus 로고    scopus 로고
    • Efficacy and mechanism of angiotensin II receptor blocker treatment in experimental abdominal aortic aneurysms
    • Iida Y, Xu B, Schultz GM, et al. Efficacy and mechanism of angiotensin II receptor blocker treatment in experimental abdominal aortic aneurysms. PLoS One 2012; 7(12): e49642.
    • (2012) PLoS One , vol.7 , Issue.12
    • Iida, Y.1    Xu, B.2    Schultz, G.M.3
  • 34
    • 0035348484 scopus 로고    scopus 로고
    • Suppression of experimental abdominal aortic aneurysms in the rat by treatment with angiotensin-converting enzyme inhibitors
    • Liao S, Miralles M, Kelley BJ, et al. Suppression of experimental abdominal aortic aneurysms in the rat by treatment with angiotensin-converting enzyme inhibitors. J Vasc Surg 2001; 33(5): 1057-64.
    • (2001) J Vasc Surg , vol.33 , Issue.5 , pp. 1057-1064
    • Liao, S.1    Miralles, M.2    Kelley, B.J.3
  • 35
    • 65449116497 scopus 로고    scopus 로고
    • Inhibition of experimental abdominal aortic aneurysm in a rat model by the angiotensin receptor blocker valsartan
    • Fujiwara Y, Shiraya S, Miyake T, et al. Inhibition of experimental abdominal aortic aneurysm in a rat model by the angiotensin receptor blocker valsartan. Int J Mol Med 2008; 22(6): 703-8.
    • (2008) Int J Mol Med , vol.22 , Issue.6 , pp. 703-708
    • Fujiwara, Y.1    Shiraya, S.2    Miyake, T.3
  • 36
    • 77951498784 scopus 로고    scopus 로고
    • Pharmacologically induced thoracic and abdominal aortic aneurysms in mice
    • Kanematsu Y, Kanematsu M, Kurihara C, et al. Pharmacologically induced thoracic and abdominal aortic aneurysms in mice. Hypertension 2010; 55(5): 1267-74.
    • (2010) Hypertension , vol.55 , Issue.5 , pp. 1267-1274
    • Kanematsu, Y.1    Kanematsu, M.2    Kurihara, C.3
  • 37
    • 66149124383 scopus 로고    scopus 로고
    • ANG II infusion promotes abdominal aortic aneurysms independent of increased blood pressure in hypercholesterolemic mice
    • Cassis LA, Gupte M, Thayer S, et al. ANG II infusion promotes abdominal aortic aneurysms independent of increased blood pressure in hypercholesterolemic mice. Am J Physiol Heart Circ Physiol 2009; 296(5): H1660-5.
    • (2009) Am J Physiol Heart Circ Physiol , vol.296 , Issue.5 , pp. H1660-H1665
    • Cassis, L.A.1    Gupte, M.2    Thayer, S.3
  • 38
    • 0042691721 scopus 로고    scopus 로고
    • Aortic dissection precedes formation of aneurysms and atherosclerosis in angiotensin IIinfused, apolipoprotein E-deficient mice
    • Saraff K, Babamusta F, Cassis LA, et al. Aortic dissection precedes formation of aneurysms and atherosclerosis in angiotensin IIinfused, apolipoprotein E-deficient mice. Arterioscler Thromb Vasc Biol 2003; 23(9): 1621-6.
    • (2003) Arterioscler Thromb Vasc Biol , vol.23 , Issue.9 , pp. 1621-1626
    • Saraff, K.1    Babamusta, F.2    Cassis, L.A.3
  • 39
    • 77954054069 scopus 로고    scopus 로고
    • Angiotensin II infusion promotes ascending aortic aneurysms: Attenuation by CCR2 deficiency in apoE-/- mice
    • Daugherty A, Rateri DL, Charo IF, et al. Angiotensin II infusion promotes ascending aortic aneurysms: attenuation by CCR2 deficiency in apoE-/- mice. Clin Sci (Lond) 2010; 118(11): 681-9.
    • (2010) Clin Sci (Lond) , vol.118 , Issue.11 , pp. 681-689
    • Daugherty, A.1    Rateri, D.L.2    Charo, I.F.3
  • 40
    • 21344441247 scopus 로고    scopus 로고
    • Bone marrow-derived monocyte chemoattractant protein-1 receptor CCR2 is critical in angiotensin II-induced acceleration of atherosclerosis and aneurysm formation in hypercholesterolemic mice
    • Ishibashi M, Egashira K, Zhao Q, et al. Bone marrow-derived monocyte chemoattractant protein-1 receptor CCR2 is critical in angiotensin II-induced acceleration of atherosclerosis and aneurysm formation in hypercholesterolemic mice. Arterioscler Thromb Vasc Biol 2004; 24(11): e174-8.
    • (2004) Arterioscler Thromb Vasc Biol , vol.24 , Issue.11 , pp. e174-e178
    • Ishibashi, M.1    Egashira, K.2    Zhao, Q.3
  • 41
    • 84875304506 scopus 로고    scopus 로고
    • Peptide inhibitor of CXCL4-CCL5 heterodimer formation, MKEY, inhibits experimental aortic aneurysm initiation and progression
    • Iida Y, Xu B, Xuan H, et al. Peptide inhibitor of CXCL4-CCL5 heterodimer formation, MKEY, inhibits experimental aortic aneurysm initiation and progression. Arterioscler Thromb Vasc Biol 2013; 33(4): 718-26.
    • (2013) Arterioscler Thromb Vasc Biol , vol.33 , Issue.4 , pp. 718-726
    • Iida, Y.1    Xu, B.2    Xuan, H.3
  • 42
    • 30944466085 scopus 로고    scopus 로고
    • Up-regulation of glomerular COX-2 by angiotensin II: Role of reactive oxygen species
    • Jaimes EA, Tian RX, Pearse D, Raij L. Up-regulation of glomerular COX-2 by angiotensin II: role of reactive oxygen species. Kidney Int 2005; 68(5): 2143-53.
    • (2005) Kidney Int , vol.68 , Issue.5 , pp. 2143-2153
    • Jaimes, E.A.1    Tian, R.X.2    Pearse, D.3    Raij, L.4
  • 43
    • 33646462753 scopus 로고    scopus 로고
    • Selective cyclooxygenase-2 inhibition with celecoxib decreases angiotensin II-induced abdominal aortic aneurysm formation in mice
    • King VL, Trivedi DB, Gitlin JM, et al. Selective cyclooxygenase-2 inhibition with celecoxib decreases angiotensin II-induced abdominal aortic aneurysm formation in mice. Arterioscler Thromb Vasc Biol 2006; 26(5): 1137-43.
    • (2006) Arterioscler Thromb Vasc Biol , vol.26 , Issue.5 , pp. 1137-1143
    • King, V.L.1    Trivedi, D.B.2    Gitlin, J.M.3
  • 44
    • 33845592174 scopus 로고    scopus 로고
    • Genetic deficiency of cyclooxygenase-2 attenuates abdominal aortic aneurysm formation in mice
    • Gitlin JM, Trivedi DB, Langenbach R, et al. Genetic deficiency of cyclooxygenase-2 attenuates abdominal aortic aneurysm formation in mice. Cardiovasc Res 2007; 73(1): 227-36.
    • (2007) Cardiovasc Res , vol.73 , Issue.1 , pp. 227-236
    • Gitlin, J.M.1    Trivedi, D.B.2    Langenbach, R.3
  • 45
    • 0347986784 scopus 로고    scopus 로고
    • Angiotensin II-accelerated atherosclerosis and aneurysm formation is attenuated in osteopontin-deficient mice
    • Bruemmer D, Collins AR, Noh G, et al. Angiotensin II-accelerated atherosclerosis and aneurysm formation is attenuated in osteopontin-deficient mice. J Clin Invest 2003; 112(9): 1318-31.
    • (2003) J Clin Invest , vol.112 , Issue.9 , pp. 1318-1331
    • Bruemmer, D.1    Collins, A.R.2    Noh, G.3
  • 46
    • 0034455957 scopus 로고    scopus 로고
    • Osteopontin: A key cytokine in cellmediated and granulomatous inflammation
    • O'Regan A, Berman JS. Osteopontin: a key cytokine in cellmediated and granulomatous inflammation. Int J Exp Pathol 2000; 81(6): 373-90.
    • (2000) Int J Exp Pathol , vol.81 , Issue.6 , pp. 373-390
    • O'Regan, A.1    Berman, J.S.2
  • 47
    • 0029089366 scopus 로고
    • Inflammation and matrix metalloproteinases in the enlarging abdominal aortic aneurysm
    • Freestone T, Turner RJ, Coady A, et al. Inflammation and matrix metalloproteinases in the enlarging abdominal aortic aneurysm. Arterioscler Thromb Vasc Biol 1995; 15(8): 1145-51.
    • (1995) Arterioscler Thromb Vasc Biol , vol.15 , Issue.8 , pp. 1145-1151
    • Freestone, T.1    Turner, R.J.2    Coady, A.3
  • 48
    • 33748799434 scopus 로고    scopus 로고
    • Early increased MT1-MMP expression and late MMP-2 and MMP-9 activity during Angiotensin II induced aneurysm formation
    • Eagleton MJ, Ballard N, Lynch E, et al. Early increased MT1-MMP expression and late MMP-2 and MMP-9 activity during Angiotensin II induced aneurysm formation. J Surg Res 2006; 135(2): 345-51.
    • (2006) J Surg Res , vol.135 , Issue.2 , pp. 345-351
    • Eagleton, M.J.1    Ballard, N.2    Lynch, E.3
  • 49
    • 0037342181 scopus 로고    scopus 로고
    • Differential effects of doxycycline, a broad-spectrum matrix metalloproteinase inhibitor, on angiotensin II-induced atherosclerosis and abdominal aortic aneurysms
    • Manning MW, Cassis LA, Daugherty A. Differential effects of doxycycline, a broad-spectrum matrix metalloproteinase inhibitor, on angiotensin II-induced atherosclerosis and abdominal aortic aneurysms. Arterioscler Thromb Vasc Biol 2003; 23(3): 483-8.
    • (2003) Arterioscler Thromb Vasc Biol , vol.23 , Issue.3 , pp. 483-488
    • Manning, M.W.1    Cassis, L.A.2    Daugherty, A.3
  • 50
    • 84862007631 scopus 로고    scopus 로고
    • Activation of AMP-activated protein kinase alpha2 by nicotine instigates formation of abdominal aortic aneurysms in mice in vivo
    • Wang S, Zhang C, Zhang M, et al. Activation of AMP-activated protein kinase alpha2 by nicotine instigates formation of abdominal aortic aneurysms in mice in vivo. Nat Med 2012; 18(6): 902-10.
    • (2012) Nat Med , vol.18 , Issue.6 , pp. 902-910
    • Wang, S.1    Zhang, C.2    Zhang, M.3
  • 51
    • 1642276271 scopus 로고    scopus 로고
    • Role of NAD(P)H oxidase on vascular alterations in angiotensin II-infused mice
    • Virdis A, Neves MF, Amiri F, et al. Role of NAD(P)H oxidase on vascular alterations in angiotensin II-infused mice. J Hypertens 2004; 22(3): 535-42.
    • (2004) J Hypertens , vol.22 , Issue.3 , pp. 535-542
    • Virdis, A.1    Neves, M.F.2    Amiri, F.3
  • 52
    • 67349235964 scopus 로고    scopus 로고
    • Cyclophilin A enhances vascular oxidative stress and the development of angiotensin II-induced aortic aneurysms
    • Satoh K, Nigro P, Matoba T, et al. Cyclophilin A enhances vascular oxidative stress and the development of angiotensin II-induced aortic aneurysms. Nat Med 2009; 15(6): 649-56.
    • (2009) Nat Med , vol.15 , Issue.6 , pp. 649-656
    • Satoh, K.1    Nigro, P.2    Matoba, T.3
  • 53
    • 23244434032 scopus 로고    scopus 로고
    • Vitamin E inhibits abdominal aortic aneurysm formation in angiotensin II-infused apolipoprotein E-deficient mice
    • Gavrila D, Li WG, McCormick ML, et al. Vitamin E inhibits abdominal aortic aneurysm formation in angiotensin II-infused apolipoprotein E-deficient mice. Arterioscler Thromb Vasc Biol 2005; 25(8): 1671-7.
    • (2005) Arterioscler Thromb Vasc Biol , vol.25 , Issue.8 , pp. 1671-1677
    • Gavrila, D.1    Li, W.G.2    McCormick, M.L.3
  • 54
    • 0036771844 scopus 로고    scopus 로고
    • AT2 receptormediated relaxation is preserved after long-term AT1 receptor blockade
    • Widdop RE, Matrougui K, Levy BI, Henrion D. AT2 receptormediated relaxation is preserved after long-term AT1 receptor blockade. Hypertension 2002; 40(4): 516-20.
    • (2002) Hypertension , vol.40 , Issue.4 , pp. 516-520
    • Widdop, R.E.1    Matrougui, K.2    Levy, B.I.3    Henrion, D.4
  • 55
    • 77957263791 scopus 로고    scopus 로고
    • The angiotensin AT2 receptor in left ventricular hypertrophy
    • Steckelings UM, Widdop RE, Paulis L, Unger T. The angiotensin AT2 receptor in left ventricular hypertrophy. J Hypertens 2010; 28 Suppl 1: S50-5.
    • (2010) J Hypertens , vol.28 , pp. S50-S55
    • Steckelings, U.M.1    Widdop, R.E.2    Paulis, L.3    Unger, T.4
  • 57
    • 79952039942 scopus 로고    scopus 로고
    • Angiotensin type 2 receptor in hypertensive cardiovascular disease
    • Savoia C, D'Agostino M, Lauri F, Volpe M. Angiotensin type 2 receptor in hypertensive cardiovascular disease. Curr Opin Nephrol Hypertens 2011; 20(2): 125-32.
    • (2011) Curr Opin Nephrol Hypertens , vol.20 , Issue.2 , pp. 125-132
    • Savoia, C.1    D'Agostino, M.2    Lauri, F.3    Volpe, M.4
  • 58
    • 79954579275 scopus 로고    scopus 로고
    • Angiotensin II type 2 receptor signaling attenuates aortic aneurysm in mice through ERK antagonism
    • Habashi JP, Doyle JJ, Holm TM. Angiotensin II type 2 receptor signaling attenuates aortic aneurysm in mice through ERK antagonism. Science 2011; 332(6027): 361-5.
    • (2011) Science , vol.332 , Issue.6027 , pp. 361-365
    • Habashi, J.P.1    Doyle, J.J.2    Holm, T.M.3
  • 59
    • 84876074729 scopus 로고    scopus 로고
    • PD123319 augments angiotensin II-induced abdominal aortic aneurysms through an AT2 receptor-independent mechanism
    • Daugherty A, Rateri DL, Howatt DA, Charnigo R, Cassis LA. PD123319 augments angiotensin II-induced abdominal aortic aneurysms through an AT2 receptor-independent mechanism. PLoS One 2013; 8(4): e61849.
    • (2013) PLoS One , vol.8 , Issue.4
    • Daugherty, A.1    Rateri, D.L.2    Howatt, D.A.3    Charnigo, R.4    Cassis, L.A.5
  • 60
    • 84876407858 scopus 로고    scopus 로고
    • Discovery and characterization of alamandine: A novel component of the reninangiotensin system
    • Lautner RQ1, Villela DC, Fraga-Silva RA, et al, Discovery and characterization of alamandine: a novel component of the reninangiotensin system. Circ Res 2013; 112(8): 1104-11.
    • (2013) Circ Res , vol.112 , Issue.8 , pp. 1104-1111
    • Lautner, R.Q.1    Villela, D.C.2    Fraga-Silva, R.A.3
  • 61
    • 0038053724 scopus 로고    scopus 로고
    • A novel angiotensinconverting enzyme-related carboxypeptidase (ACE2) converts angiotensin I to angiotensin 1-9
    • Donoghue M, Hsieh F, Baronas E, et al. A novel angiotensinconverting enzyme-related carboxypeptidase (ACE2) converts angiotensin I to angiotensin 1-9. Circ Res 2000; 87(5): E1-9.
    • (2000) Circ Res , vol.87 , Issue.5 , pp. E1-E9
    • Donoghue, M.1    Hsieh, F.2    Baronas, E.3
  • 62
    • 18544378161 scopus 로고    scopus 로고
    • Hydrolysis of biological peptides by human angiotensin-converting enzyme-related carboxypeptidase
    • Vickers C1, Hales P, Kaushik V, et al. Hydrolysis of biological peptides by human angiotensin-converting enzyme-related carboxypeptidase. J Biol Chem 2002; 277(17): 14838-43.
    • (2002) J Biol Chem , vol.277 , Issue.17 , pp. 14838-14843
    • Vickers, C.1    Hales, P.2    Kaushik, V.3
  • 63
    • 79851511993 scopus 로고    scopus 로고
    • ACE2: More of Ang-(1-7) or less Ang II?
    • Ferrario CM. ACE2: more of Ang-(1-7) or less Ang II? Curr Opin Nephrol Hypertens 2011; 20(1): 1-6.
    • (2011) Curr Opin Nephrol Hypertens , vol.20 , Issue.1 , pp. 1-6
    • Ferrario, C.M.1
  • 64
    • 84872602247 scopus 로고    scopus 로고
    • Opportunities for targeting the angiotensin-converting enzyme 2/angiotensin-(1- 7)/mas receptor pathway in hypertension
    • Fraga-Silva RA, Ferreira AJ, Dos Santos RA. Opportunities for targeting the angiotensin-converting enzyme 2/angiotensin-(1- 7)/mas receptor pathway in hypertension. Curr Hypertens Rep 2013; 15(1): 31-8.
    • (2013) Curr Hypertens Rep , vol.15 , Issue.1 , pp. 31-38
    • Fraga-Silva, R.A.1    Ferreira, A.J.2    Dos Santos, R.A.3
  • 65
    • 84861511222 scopus 로고    scopus 로고
    • New cardiovascular and pulmonary therapeutic strategies based on the Angiotensin-converting enzyme 2/angiotensin-(1-7)/mas receptor axis
    • Ferreira AJ1, Murça TM, Fraga-Silva RA, Castro CH, Raizada MK, Santos RA. New cardiovascular and pulmonary therapeutic strategies based on the Angiotensin-converting enzyme 2/angiotensin-(1-7)/mas receptor axis. Int J Hypertens 2012; 2012: 147825.
    • (2012) Int J Hypertens , vol.2012
    • Ferreira, A.J.1    Murça, T.M.2    Fraga-Silva, R.A.3    Castro, C.H.4    Raizada, M.K.5    Santos, R.A.6
  • 66
    • 74949087578 scopus 로고    scopus 로고
    • Therapeutic implications of the vasoprotective axis of the renin-angiotensin system in cardiovascular diseases
    • Ferreira AJ, Santos RA, Bradford CN, et al. Therapeutic implications of the vasoprotective axis of the renin-angiotensin system in cardiovascular diseases. Hypertension 2010; 55(2): 207- 13.
    • (2010) Hypertension , vol.55 , Issue.2 , pp. 207-213
    • Ferreira, A.J.1    Santos, R.A.2    Bradford, C.N.3
  • 67
    • 84918493360 scopus 로고    scopus 로고
    • Angiotensin-converting enzyme 2 decreases formation and severity of angiotensin II-induced abdominal aortic aneurysms
    • Thatcher SE. Angiotensin-converting enzyme 2 decreases formation and severity of angiotensin II-induced abdominal aortic aneurysms. Arterioscler Thromb Vasc Biol 2014; 34(12): 2617-23.
    • (2014) Arterioscler Thromb Vasc Biol , vol.34 , Issue.12 , pp. 2617-2623
    • Thatcher, S.E.1
  • 68
    • 34547951696 scopus 로고    scopus 로고
    • Novel drugs targeting hypertension: Renin inhibitors
    • Danser AH. Novel drugs targeting hypertension: renin inhibitors. J Cardiovasc Pharmacol 2007; 50(2): 105-11.
    • (2007) J Cardiovasc Pharmacol , vol.50 , Issue.2 , pp. 105-111
    • Danser, A.H.1
  • 69
    • 84897560702 scopus 로고    scopus 로고
    • Aliskiren limits abdominal aortic aneurysm, ventricular hypertrophy and atherosclerosis in an apolipoprotein-E-deficient mouse model
    • Seto SW. Aliskiren limits abdominal aortic aneurysm, ventricular hypertrophy and atherosclerosis in an apolipoprotein-E-deficient mouse model. Clin Sci (Lond) 2014; 127(2): 123-34.
    • (2014) Clin Sci (Lond) , vol.127 , Issue.2 , pp. 123-134
    • Seto, S.W.1
  • 70
    • 0031694482 scopus 로고    scopus 로고
    • Matrix metalloproteinase-2 production and its binding to the matrix are increased in abdominal aortic aneurysms
    • Davis V, Persidskaia R, Baca-Regen L, et al. Matrix metalloproteinase-2 production and its binding to the matrix are increased in abdominal aortic aneurysms. Arterioscler Thromb Vasc Biol 1998; 18(10): 1625-33.
    • (1998) Arterioscler Thromb Vasc Biol , vol.18 , Issue.10 , pp. 1625-1633
    • Davis, V.1    Persidskaia, R.2    Baca-Regen, L.3
  • 71
    • 0030025802 scopus 로고    scopus 로고
    • Doxycycline inhibition of aneurysmal degeneration in an elastase-induced rat model of abdominal aortic aneurysm: Preservation of aortic elastin associated with suppressed production of 92 kD gelatinase
    • Petrinec D, Liao S, Holmes DR, Reilly JM, Parks WC, Thompson RW. Doxycycline inhibition of aneurysmal degeneration in an elastase-induced rat model of abdominal aortic aneurysm: preservation of aortic elastin associated with suppressed production of 92 kD gelatinase. J Vasc Surg 1996; 23(2): 336-46.
    • (1996) J Vasc Surg , vol.23 , Issue.2 , pp. 336-346
    • Petrinec, D.1    Liao, S.2    Holmes, D.R.3    Reilly, J.M.4    Parks, W.C.5    Thompson, R.W.6
  • 72
    • 0036584883 scopus 로고    scopus 로고
    • Doxycycline in patients with abdominal aortic aneurysms and in mice: Comparison of serum levels and effect on aneurysm growth in mice
    • Prall AK. Doxycycline in patients with abdominal aortic aneurysms and in mice: comparison of serum levels and effect on aneurysm growth in mice. J Vasc Surg 2002; 35(5): 923-9.
    • (2002) J Vasc Surg , vol.35 , Issue.5 , pp. 923-929
    • Prall, A.K.1
  • 73
    • 40749083602 scopus 로고    scopus 로고
    • A novel histone deacetylase inhibitor reduces abdominal aortic aneurysm formation in angiotensin II-infused apolipoprotein E-deficient mice
    • Vinh A. A novel histone deacetylase inhibitor reduces abdominal aortic aneurysm formation in angiotensin II-infused apolipoprotein E-deficient mice. J Vasc Res 2008; 45(2): 143-52.
    • (2008) J Vasc Res , vol.45 , Issue.2 , pp. 143-152
    • Vinh, A.1
  • 74
    • 0031743329 scopus 로고    scopus 로고
    • Pharmacologic suppression of experimental abdominal aortic aneurysms: Acomparison of doxycycline and four chemically modified tetracyclines
    • Curci JA. Pharmacologic suppression of experimental abdominal aortic aneurysms: acomparison of doxycycline and four chemically modified tetracyclines. J Vasc Surg 1998; 28(6): 1082-93.
    • (1998) J Vasc Surg , vol.28 , Issue.6 , pp. 1082-1093
    • Curci, J.A.1
  • 75
    • 84866893810 scopus 로고    scopus 로고
    • Doxycycline does not influence established abdominal aortic aneurysms in angiotensin II-infused mice
    • Xie X. Doxycycline does not influence established abdominal aortic aneurysms in angiotensin II-infused mice. PLoS One 2012; 7(9): e46411.
    • (2012) PLoS One , vol.7 , Issue.9
    • Xie, X.1
  • 76
    • 0033977883 scopus 로고    scopus 로고
    • Preoperative treatment with doxycycline reduces aortic wall expression and activation of matrix metalloproteinases in patients with abdominal aortic aneurysms
    • Curci JA. Preoperative treatment with doxycycline reduces aortic wall expression and activation of matrix metalloproteinases in patients with abdominal aortic aneurysms. J Vasc Surg 2000; 31(2): 325-42.
    • (2000) J Vasc Surg , vol.31 , Issue.2 , pp. 325-342
    • Curci, J.A.1
  • 77
    • 0036634195 scopus 로고    scopus 로고
    • Prolonged administration of doxycycline in patients with small asymptomatic abdominal aortic aneurysms: Report of a prospective (Phase II) multicenter study
    • Baxter BT. Prolonged administration of doxycycline in patients with small asymptomatic abdominal aortic aneurysms: report of a prospective (Phase II) multicenter study. J Vasc Surg 2002; 36(1): 1-12.
    • (2002) J Vasc Surg , vol.36 , Issue.1 , pp. 1-12
    • Baxter, B.T.1
  • 78
    • 0035488854 scopus 로고    scopus 로고
    • Use of doxycycline to decrease the growth rate of abdominal aortic aneurysms: A randomized, double-blind, placebo-controlled pilot study
    • Mosorin M, Juvonen J, Biancari F, et al. Use of doxycycline to decrease the growth rate of abdominal aortic aneurysms: a randomized, double-blind, placebo-controlled pilot study. J Vasc Surg 2001; 34(4): 606-10.
    • (2001) J Vasc Surg , vol.34 , Issue.4 , pp. 606-610
    • Mosorin, M.1    Juvonen, J.2    Biancari, F.3
  • 79
    • 0031055721 scopus 로고    scopus 로고
    • Prevalence and associations of abdominal aortic aneurysm detected through screening. Aneurysm Detection and Management (ADAM) Veterans Affairs Cooperative Study Group
    • Liu J, Xiong W, Baca-Regen L, Nagase H, Baxter BT. Prevalence and associations of abdominal aortic aneurysm detected through screening. Aneurysm Detection and Management (ADAM) Veterans Affairs Cooperative Study Group. Ann Intern Med 1997; 126(6): 441-9.
    • (1997) Ann Intern Med , vol.126 , Issue.6 , pp. 441-449
    • Liu, J.1    Xiong, W.2    Baca-Regen, L.3    Nagase, H.4    Baxter, B.T.5
  • 80
    • 0345167810 scopus 로고    scopus 로고
    • Mechanism of inhibition of matrix metalloproteinase-2 expression by doxycycline in human aortic smooth muscle cells
    • Liu J, Xiong W, Baca-Regen L, Nagase H, Baxter BT. Mechanism of inhibition of matrix metalloproteinase-2 expression by doxycycline in human aortic smooth muscle cells. J Vasc Surg 2003; 38(6): 1376-83.
    • (2003) J Vasc Surg , vol.38 , Issue.6 , pp. 1376-1383
    • Liu, J.1    Xiong, W.2    Baca-Regen, L.3    Nagase, H.4    Baxter, B.T.5
  • 82
    • 66549112936 scopus 로고    scopus 로고
    • Clinical trial of doxycycline for matrix metalloproteinase-9 inhibition in patients with an abdominal aneurysm: Doxycycline selectively depletes aortic wall neutrophils and cytotoxic T cells
    • Lindeman JH, Abdul-Hussien H, van Bockel JH, Wolterbeek R, Kleemann R. Clinical trial of doxycycline for matrix metalloproteinase-9 inhibition in patients with an abdominal aneurysm: doxycycline selectively depletes aortic wall neutrophils and cytotoxic T cells. Circulation 2009; 119(16): 2209-16.
    • (2009) Circulation , vol.119 , Issue.16 , pp. 2209-2216
    • Lindeman, J.H.1    Abdul-Hussien, H.2    van Bockel, J.H.3    Wolterbeek, R.4    Kleemann, R.5
  • 83
    • 84891444972 scopus 로고    scopus 로고
    • Doxycycline for stabilization of abdominal aortic aneurysms: A randomized trial
    • Meijer CA, Stijnen T, Wasser MN, et al. Doxycycline for stabilization of abdominal aortic aneurysms: a randomized trial. Ann Intern Med 2013; 159(12): 815-23.
    • (2013) Ann Intern Med , vol.159 , Issue.12 , pp. 815-823
    • Meijer, C.A.1    Stijnen, T.2    Wasser, M.N.3
  • 84
    • 79955148909 scopus 로고    scopus 로고
    • A clinical perspective of IL-1beta as the gatekeeper of inflammation
    • Dinarello CA. A clinical perspective of IL-1beta as the gatekeeper of inflammation. Eur J Immunol 2011; 41(5): 1203-17.
    • (2011) Eur J Immunol , vol.41 , Issue.5 , pp. 1203-1217
    • Dinarello, C.A.1
  • 85
    • 84872909085 scopus 로고    scopus 로고
    • Genetic and pharmacologic disruption of interleukin- 1beta signaling inhibits experimental aortic aneurysm formation
    • Johnston WF. Genetic and pharmacologic disruption of interleukin- 1beta signaling inhibits experimental aortic aneurysm formation. Arterioscler Thromb Vasc Biol 2013; 33(2): 294-304.
    • (2013) Arterioscler Thromb Vasc Biol , vol.33 , Issue.2 , pp. 294-304
    • Johnston, W.F.1
  • 86
    • 17344366565 scopus 로고    scopus 로고
    • Elevated circulating levels of inflammatory cytokines in patients with abdominal aortic aneurysm
    • Juvonen J. Elevated circulating levels of inflammatory cytokines in patients with abdominal aortic aneurysm. Arterioscler Thromb Vasc Biol 1997; 17(11): 2843-7.
    • (1997) Arterioscler Thromb Vasc Biol , vol.17 , Issue.11 , pp. 2843-2847
    • Juvonen, J.1
  • 87
    • 0026441394 scopus 로고
    • Interleukin-1 beta and tumor necrosis factor-alpha release in normal and diseased human infrarenal aortas
    • Pearce WH. Interleukin-1 beta and tumor necrosis factor-alpha release in normal and diseased human infrarenal aortas. J Vasc Surg 1992; 16(5): 784-9.
    • (1992) J Vasc Surg , vol.16 , Issue.5 , pp. 784-789
    • Pearce, W.H.1
  • 88
    • 84878915614 scopus 로고    scopus 로고
    • Potential role for anti-angiogenic therapy in abdominal aortic aneurysms
    • Vijaynagar B. Potential role for anti-angiogenic therapy in abdominal aortic aneurysms. Eur J Clin Invest 2013; 43(7): 758-65.
    • (2013) Eur J Clin Invest , vol.43 , Issue.7 , pp. 758-765
    • Vijaynagar, B.1
  • 89
    • 0029063650 scopus 로고
    • Medial neovascularization in abdominal aortic aneurysms: A histopathologic marker of aneurysmal degeneration with pathophysiologic implications
    • Holmes DR. Medial neovascularization in abdominal aortic aneurysms: a histopathologic marker of aneurysmal degeneration with pathophysiologic implications. J Vasc Surg 1995; 21(5): 761- 71.
    • (1995) J Vasc Surg , vol.21 , Issue.5 , pp. 761-771
    • Holmes, D.R.1
  • 90
    • 0029984855 scopus 로고    scopus 로고
    • Angiogenesis in abdominal aortic aneurysms
    • Thompson MM. Angiogenesis in abdominal aortic aneurysms. Eur J Vasc Endovasc Surg 1996; 11(4): 464-9.
    • (1996) Eur J Vasc Endovasc Surg , vol.11 , Issue.4 , pp. 464-469
    • Thompson, M.M.1
  • 91
    • 0036389613 scopus 로고    scopus 로고
    • Expression of angiogenesis and angiogenic factors in human aortic vascular disease
    • Kobayashi M. Expression of angiogenesis and angiogenic factors in human aortic vascular disease. J Surg Res 2002; 106(2): 239-45.
    • (2002) J Surg Res , vol.106 , Issue.2 , pp. 239-245
    • Kobayashi, M.1
  • 92
    • 77953684617 scopus 로고    scopus 로고
    • Vascular endothelial growth factor enhances angiotensin II-induced aneurysm formation in apolipoprotein E-deficient mice
    • Choke E, Cockerill GW, Dawson J, et al. Vascular endothelial growth factor enhances angiotensin II-induced aneurysm formation in apolipoprotein E-deficient mice. J Vasc Surg 2010; 52(1): 159- 166.
    • (2010) J Vasc Surg , vol.52 , Issue.1 , pp. 159-166
    • Choke, E.1    Cockerill, G.W.2    Dawson, J.3
  • 93
    • 12344270825 scopus 로고    scopus 로고
    • Ongoing angiogenesis in blood vessels of the abdominal aortic aneurysm
    • Paik DC, Fu C, Bhattacharya J, Tilson MD. Ongoing angiogenesis in blood vessels of the abdominal aortic aneurysm. Exp Mol Med 2004; 36(6): 524-33.
    • (2004) Exp Mol Med , vol.36 , Issue.6 , pp. 524-533
    • Paik, D.C.1    Fu, C.2    Bhattacharya, J.3    Tilson, M.D.4
  • 94
    • 33747379850 scopus 로고    scopus 로고
    • Abdominal aortic aneurysm rupture is associated with increased medial neovascularization and overexpression of proangiogenic cytokines
    • Choke E. Abdominal aortic aneurysm rupture is associated with increased medial neovascularization and overexpression of proangiogenic cytokines. Arterioscler Thromb Vasc Biol 2006; 26(9): 2077-82.
    • (2006) Arterioscler Thromb Vasc Biol , vol.26 , Issue.9 , pp. 2077-2082
    • Choke, E.1
  • 95
    • 2442621619 scopus 로고    scopus 로고
    • Discovery and development of bevacizumab, an anti- VEGF antibody for treating cancer
    • Ferrara N. Discovery and development of bevacizumab, an anti- VEGF antibody for treating cancer. Nat Rev Drug Discov 2004; 3(5): 391-400.
    • (2004) Nat Rev Drug Discov , vol.3 , Issue.5 , pp. 391-400
    • Ferrara, N.1
  • 96
    • 79960005595 scopus 로고    scopus 로고
    • Role of vascular endothelial growth factor-A in development of abdominal aortic aneurysm
    • Kaneko H. Role of vascular endothelial growth factor-A in development of abdominal aortic aneurysm. Cardiovasc Res 2011; 91(2): 358-67.
    • (2011) Cardiovasc Res , vol.91 , Issue.2 , pp. 358-367
    • Kaneko, H.1
  • 97
    • 84896895993 scopus 로고    scopus 로고
    • Rupture of abdominal aortic aneurysm after intravitreal bevacizumab injection: A case report
    • Baek SU, Kwon SI, Rupture of abdominal aortic aneurysm after intravitreal bevacizumab injection: a case report. J Med Case Rep 2014; 8: 48.
    • (2014) J Med Case Rep , vol.8 , pp. 48
    • Baek, S.U.1    Kwon, S.I.2
  • 101
    • 84914696664 scopus 로고    scopus 로고
    • Vasoprotective effects of urocortin 1 against atherosclerosis in vitro and in vivo
    • Hasegawa A, Sato K, Shirai R, et al. Vasoprotective effects of urocortin 1 against atherosclerosis in vitro and in vivo. PLoS One 2014; 9(12): e110866.
    • (2014) PLoS One , vol.9 , Issue.12
    • Hasegawa, A.1    Sato, K.2    Shirai, R.3
  • 102
    • 84891472614 scopus 로고    scopus 로고
    • Urocortin 2 is associated with abdominal aortic aneurysm and mediates anti-proliferative effects on vascular smooth muscle cells via corticotrophin releasing factor receptor 2
    • Emeto TI, Moxon JV, Biros E, et al. Urocortin 2 is associated with abdominal aortic aneurysm and mediates anti-proliferative effects on vascular smooth muscle cells via corticotrophin releasing factor receptor 2. Clin Sci (Lond) 2014; 126(7): 517-27.
    • (2014) Clin Sci (Lond) , vol.126 , Issue.7 , pp. 517-527
    • Emeto, T.I.1    Moxon, J.V.2    Biros, E.3
  • 103
    • 68949157076 scopus 로고    scopus 로고
    • Whole genome expression analysis within the angiotensin II-apolipoprotein E deficient mouse model of abdominal aortic aneurysm
    • Rush C, Nyara M, Moxon JV, et al. Whole genome expression analysis within the angiotensin II-apolipoprotein E deficient mouse model of abdominal aortic aneurysm. BMC Genomics 2009; 10: 298.
    • (2009) BMC Genomics , vol.10 , pp. 298
    • Rush, C.1    Nyara, M.2    Moxon, J.V.3
  • 104
    • 32644490150 scopus 로고    scopus 로고
    • Endothelial urocortin has potent antioxidative properties and is upregulated by inflammatory cytokines and pitavastatin
    • Honjo T, Inoue N, Shiraki R, et al. Endothelial urocortin has potent antioxidative properties and is upregulated by inflammatory cytokines and pitavastatin. J Vasc Res 2006; 43(2): 131-8.
    • (2006) J Vasc Res , vol.43 , Issue.2 , pp. 131-138
    • Honjo, T.1    Inoue, N.2    Shiraki, R.3
  • 105
    • 0037188537 scopus 로고    scopus 로고
    • Corticotropin-releasing factor receptor 2 is a tonic suppressor of vascularization
    • Bale TL, Giordano FJ, Hickey RP, et al. Corticotropin-releasing factor receptor 2 is a tonic suppressor of vascularization. Proc Natl Acad Sci USA 2002; 99(11): 7734-9.
    • (2002) Proc Natl Acad Sci USA , vol.99 , Issue.11 , pp. 7734-7739
    • Bale, T.L.1    Giordano, F.J.2    Hickey, R.P.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.