ANG II infusion promotes abdominal aortic aneurysms independent of increased blood pressure in hypercholesterolemic mice

American Journal of Physiology - Heart and Circulatory Physiology

Volumn 296, Issue 5, 2009, Pages

  Cassis, Lisa A ^a   Gupte, Manisha ^a   Thayer, Sarah ^a   Zhang, Xuan ^a   Charnigo, Richard ^a   Howatt, Deborah A ^a   Rateri, Debra L ^a   Daugherty, Alan ^a  

^a UNIVERSITY OF KENTUCKY   (United States)

Author keywords

Aneurysms; Hypertension; Vascular lesions

Indexed keywords

ANGIOTENSIN II; APOLIPOPROTEIN E; CHOLESTEROL; HYDRALAZINE; LOW DENSITY LIPOPROTEIN RECEPTOR; NORADRENALIN;

ABDOMINAL AORTA ANEURYSM; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; ATHEROSCLEROSIS; CONTROLLED STUDY; DISEASE COURSE; HYPERCHOLESTEROLEMIA; HYPERTENSION; MALE; MEAN ARTERIAL PRESSURE; MOUSE; NONHUMAN; PRIORITY JOURNAL; SYSTOLIC BLOOD PRESSURE; TELEMETRY;

ANGIOTENSIN II; ANIMALS; ANTIHYPERTENSIVE AGENTS; AORTIC ANEURYSM, ABDOMINAL; APOLIPOPROTEINS E; ATHEROSCLEROSIS; BLOOD PRESSURE; CHOLESTEROL, DIETARY; DISEASE MODELS, ANIMAL; HYDRALAZINE; HYPERCHOLESTEROLEMIA; HYPERTENSION; INFUSION PUMPS, IMPLANTABLE; MALE; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; NOREPINEPHRINE; RECEPTORS, LDL; RISK FACTORS; TIME FACTORS;

EID: 66149124383     PISSN: 03636135     EISSN: 15221539     Source Type: Journal    
DOI: 10.1152/ajpheart.00028.2009     Document Type: Article

References (33)

1. Ahluwalia N, Lin AY, Tager AM, Pruitt IE, Anderson TJ, Kristo F, Shen D, Cruz AR, Aikawa M, Luster AD, Gerszten RE. Inhibited aortic aneurysm formation in BLT1-deficient mice. J Immunol 179: 691-697, 2007. (Pubitemid 46986588)
2. Barisione C, Charnigo R, Howatt DA, Moorleghen JJ, Rateri DL, Daugherty A. Rapid dilation of the abdominal aorta during infusion of angiotensin II detected by noninvasive high-frequency ultrasonography. J Vasc Surg 44: 372-376, 2006. (Pubitemid 44142945)
3. Brooke BS, Habashi JP, Judge DP, Patel N, Loeys B, Dietz HC. Angiotensin II blockade and aortic root dilation in Marfan's syndrome. N Engl J Med 358: 2787-2795, 2008.
4. Bruemmer D, Collins AR, Noh G, Wang W, Territo M, Arias-Magallona S, Fishbein MC, Blaschke F, Kintscher U, Graf K, Law RE, Hsueh WA. Angiotensin II-accelerated atherosclerosis and aneurysm formation is attenuated in osteopontin-deficient mice. J Clin Invest 112: 1318-1331, 2003. (Pubitemid 38057686)
5. Cassis LA, Huang J, Gong MC, Daugherty A. Role of metabolism and receptor responsiveness in the attenuated responses to angiotensin II in mice compared to rats. Regul Pept 117: 107-116, 2004. (Pubitemid 38045332)
6. Cassis LA, Rateri DL, Lu H, Daugherty A. Bone marrow transplantation reveals that recipient AT1a receptors are required to initiate angiotensin II-induced atherosclerosis and aneurysms. Arterioscler Thromb Vasc Biol 27: 380-386, 2007. (Pubitemid 46143055)
7. -/- mice. Ann NY Acad Sci 892: 108-118, 1999.
8. Daugherty A, Cassis L. Angiotensin II-mediated development of vascular diseases. Trends Cardiovasc Med 14: 117-120, 2004. (Pubitemid 38569679)
9. Daugherty A, Cassis LA. Mouse models of abdominal aortic aneurysms. Arterioscler Thromb Vasc Biol 24: 429-434, 2004. (Pubitemid 38326134)
10. Daugherty A, Manning MW, Cassis LA. Angiotensin II promotes atherosclerotic lesions and aneurysms in apolipoprotein E-deficient mice. J Clin Invest 105: 1605-1612, 2000. (Pubitemid 30390311)
11. Daugherty A, Manning MW, Cassis LA. Antagonism of AT2 receptors augments angiotensin II-induced abdominal aortic aneurysms and atherosclerosis. Br J Pharmacol 134: 865-870, 2001. (Pubitemid 33016158)
12. Daugherty A, Rateri DL, Lu H, Inagami T, Cassis LA. Hypercholesterolemia stimulates angiotensin peptide synthesis and contributes to atherosclerosis through the AT1A receptor. Circulation 110: 3849-3857, 2004. (Pubitemid 40023984)
13. Daugherty A, Whitman SC. Quantification of atherosclerosis in mice. Methods Mol Biol 209: 293-309, 2003.
14. Deng GG, Martin-McNulty B, Sukovich DA, Freay A, Halks-Miller M, Thinnes T, Loskutoff DJ, Carmeliet P, Dole WP, Wang YX. Urokinase-type plasminogen activator plays a critical role in angiotensin II-induced abdominal aortic aneurysm. Circ Res 92: 510-517, 2003. (Pubitemid 36368663)
15. Gadowski GR, Ricci MA, Hendley ED, Pilcher DB. Hypertension accelerates the growth of experimental aortic aneurysms. J Surg Res 54: 431-436, 1993.
16. Gavrila D, Li WG, McCormick ML, Thomas M, Daugherty A, Cassis LA, Miller FJ Jr, Oberley LW, Dellsperger KC, Weintraub NL. Vitamin E inhibits abdominal aortic aneurysm formation in angiotensin II-infused apolipoprotein E-deficient mice. Arterioscler Thromb Vasc Biol 25: 1671-1677, 2005. (Pubitemid 41098939)
17. Hackam DG, Thiruchelvam D, Redelmeier DA. Angiotensin-converting enzyme inhibitors and aortic rupture: a population-based case-control study. Lancet 368: 659-665, 2006. (Pubitemid 44226485)
18. Henriques T, Zhang X, Yiannikouris FB, Daugherty A, Cassis LA. Androgen increases AT1a receptor expression in abdominal aortas to promote angiotensin II-induced AAAs in apolipoprotein E-deficient mice. Arterioscler Thromb Vasc Biol 28: 1251-1256, 2008.
19. Henriques TA, Huang J, D'Souza SS, Daugherty A, Cassis LA. Orchidectomy, but not ovariectomy, regulates angiotensin II-induced vascular diseases in apolipoprotein E-deficient mice. Endocrinology 145: 3866-3872, 2004. (Pubitemid 39037575)
20. Heo HJ, Yun MR, Jung KH, Lee JY, Park JY, Lee SJ, Bae SS, Lee WS, Kim CD. Endogenous angiotensin II enhances atherogenesis in apoprotein E-deficient mice with renovascular hypertension through activation of vascular smooth muscle cells. Life Sci 80: 1057-1063, 2007.
21. Hobbs S, Claridge M, Drage M, Quick C, Bradbury A, Wilmink A. Strategies to improve the effectiveness of abdominal aortic aneurysm screening programmes. J Med Screen 11: 93-96, 2004. (Pubitemid 38829887)
22. King VL, Trivedi DB, Gitlin JM, Loftin CD. Selective cyclooxygenase-2 inhibition with celecoxib decreases angiotensin II-induced abdominal aortic aneurysm formation in mice. Arterioscler Thromb Vasc Biol 26: 1137-1143, 2006.
23. Lederle FA, Johnson GR, Wilson SE, Chute EP, Hye RJ, Makaroun MS, Barone GW, Bandyk D, Moneta GL, Makhoul RG. The aneurysm detection and management study screening program: validation cohort and final results. Aneurysm Detection and Management Veterans Affairs Cooperative Study Investigators. Arch Intern Med 160: 1425-1430, 2000.
24. Lindholt JS, Henneberg EW, Juul S, Fasting H. Impaired results of a randomised double blinded clinical trial of propranolol versus placebo on the expansion rate of small abdominal aortic aneurysms. Int Angiol 18: 52-57, 1999. (Pubitemid 29253669)
25. Lu H, Rateri DL, Feldman RJ DL Jr, Fukamizu A, Ishida J, Oesterling EG, Cassis LA, Daugherty A. Renin inhibition reduces hypercholesterolemia-induced atherosclerosis in mice. J Clin Invest 118: 984-993, 2008.
26. Manning MW, Cassis LA, Daugherty A. Differential effects of doxycycline, a broad-spectrum matrix metalloproteinase inhibitor, on angiotensin II-induced atherosclerosis and abdominal aortic aneurysms. Arterioscler Thromb Vasc Biol 23: 483-488, 2003.
27. Martin-McNulty B, Tham DM, da Cunha V, Ho JJ, Wilson DW, Rutledge JC, Deng GG, Vergona R, Sullivan ME, Wang YX. 17 Beta-estradiol attenuates development of angiotensin II-induced aortic abdominal aneurysm in apolipoprotein E-deficient mice. Arterioscler Thromb Vasc Biol 23: 1627-1632, 2003.
28. Nishijo N, Sugiyama F, Kimoto K, Taniguchi K, Murakami K, Suzuki S, Fukamizu A, Yagami K. Salt-sensitive aortic aneurysm and rupture in hypertensive transgenic mice that overproduce angiotensin II. Lab Invest 78: 1059-1066, 1998. (Pubitemid 28440822)
29. Peach MJ. Renin-angiotensin system: biochemistry and mechanisms of action. Physiol Rev 57: 313-370, 1977.
30. Ricci MA, Slaiby JM, Gadowski GR, Hendley ED, Nichols P, Pilcher DB. Effects of hypertension and propranolol upon aneurysm expansion in the Anidjar/Dobrin aneurysm model. Ann NY Acad Sci 800: 89-96, 1996. (Pubitemid 27028947)
31. Saraff K, Babamusta F, Cassis LA, Daugherty A. Aortic dissection precedes formation of aneurysms and atherosclerosis in angiotensin II-infused, apolipoprotein E-deficient mice. Arterioscler Thromb Vasc Biol 23: 1621-1626, 2003. (Pubitemid 37108207)
32. Slaiby JM, Ricci MA, Gadowski GR, Hendley ED, Pilcher DB. Expansion of aortic aneurysms is reduced by propranolol in a hypertensive rat model. J Vasc Surg 20: 178-183, 1994.
33. Weiss D, Kools JJ, Taylor WR. Angiotensin II-induced hypertension accelerates the development of atherosclerosis in apoE-deficient mice. Circulation 103: 448-454, 2001. (Pubitemid 32105987)