Plasma urocortin in human systolic heart failure

Clinical Science

Volumn 106, Issue 4, 2004, Pages 383-388

  Ng, Leong ^a   Loke, Ian W ^a   O'Brien, Russell J ^a   Squire, Iain B ^a   Davies, Joan E ^a  

^a UNIVERSITY OF LEICESTER   (United Kingdom)

Author keywords

Heart failure; Natriuretic peptide; Urocortin

Indexed keywords

BETA ADRENERGIC RECEPTOR BLOCKING AGENT; BIOLOGICAL MARKER; BRAIN NATRIURETIC PEPTIDE; DIGOXIN; DIPEPTIDYL CARBOXYPEPTIDASE INHIBITOR; LOOP DIURETIC AGENT; SPIRONOLACTONE; UROCORTIN;

ADULT; AGED; AREA UNDER THE CURVE; ARTICLE; CONTROLLED STUDY; CORRELATION ANALYSIS; DISEASE SEVERITY; FEMALE; HEART EJECTION FRACTION; HEART FAILURE; HUMAN; MAJOR CLINICAL STUDY; MALE; PRIORITY JOURNAL; PROTEIN BLOOD LEVEL; SCORING SYSTEM; SEX DIFFERENCE; STATISTICAL SIGNIFICANCE; SYSTOLE;

ADULT; AGED; AGED, 80 AND OVER; AREA UNDER CURVE; BIOLOGICAL MARKERS; CASE-CONTROL STUDIES; CORTICOTROPIN-RELEASING HORMONE; DISEASE PROGRESSION; FEMALE; GENDER IDENTITY; HEART FAILURE, CONGESTIVE; HUMANS; LOGISTIC MODELS; MALE; MIDDLE AGED; NATRIURETIC PEPTIDE, BRAIN; PREDICTIVE VALUE OF TESTS; SYSTOLE;

EID: 2142639428     PISSN: 01435221     EISSN: None     Source Type: Journal    
DOI: 10.1042/CS20030311     Document Type: Article

References (17)

1. Vaughan, J., Donaldson, C., Bittencourt, J. et al. (1995) Urocortin, a mammalian neuropeptide related to fish urotensin I and to corticotropin- releasing factor. Nature (London) 378, 287-292
2. Perrin, M., Donaldson, C., Chen, R. et al. (1995) Identification of a second corticotropin-releasing factor receptor gene and characterization of a cDNA expressed in heart. Proc. Natl. Acad. Sci. U.S.A. 92, 2969-2973
3. Parkes, D. G., Vaughan, J., Rivier, J. et al. (1997) Cardiac inotropic actions of urocortin in conscious sheep. Am. J. Physiol. 272, H2115-H2122
4. Coste, S. C., Kesterson, R. A., Heldwein, K. A. et al. (2000) Abnormal adaptations to stress and impaired cardiovascular function in mice lacking corticotropin-releasing hormone receptor-2. Nat. Genet. 24, 403-409
5. Nishikimi, T., Miyata, A., Horio, T. et al. (2000) Urocortin, a member of the corticotropin-releasing factor family, in normal and diseased heart. Am. J. Physiol. Heart Circ. Physiol. 279, H3031-H3039
6. Brar, B. K., Jonassen, A. K., Stephanou, A. et al. (2000) Urocortin protects against ischemic and reperfusion injury via a MAPK-dependent pathway. J. Biol. Chem. 275, 8508-8514
7. Rademaker, M. T., Charles, C. J., Espiner, E. A. et al. (2002) Beneficial hemodynamic, endocrine, and renal effects of urocortin in experimental heart failure. Comparison with normal sheep. J. Am. Coll. Cardiol. 40, 1495-1505
8. Schiller, N. B., Shah, P. M., Crawford, M. et al. (1989) Recommendations for quantitation of the left ventricle by two-dimensional echocardiography. American Society of Echocardiography Committee on Standards, Subcommittee on Quantitation of Two-Dimensional Echocardiograms. J. Am. Soc. Echocardiogr. 2, 358-367
9. Ng, L. L., O'Brien, R. J., Demme, B. and Jennings, S. (2002) A non-competitive immunochemiluminometric assay for cardiotrophin-1 detects elevated plasma levels in human heart failure. Clin. Sci. 102, 411-416
10. Ng, L. L., Loke, I., O'Brien, R. J., Squire, I. B. and Davies, J. E. (2002) Plasma urotensin in human systolic heart failure. Circulation 106, 2877-2880
11. Hanley, J. A. and McNeil, B. J. (1982) The meaning and use of the area under a receiver operating characteristic (ROC) curve. Radiology 143, 29-36
12. Turnbull, A. V., Vale, W. and Rivier, C. (1996) Urocortin, a corticotropin-releasing factor-related mammalian peptide, inhibits edema due to thermal injury in rats. Eur. J. Pharmacol. 303, 213-216
13. Agnello, D., Bertini, R., Sacco, S. et al. (1998) Corticosteroid- independent inhibition of tumor necrosis factor production by the neuropeptide urocortin. Am. J. Physiol. 275, E757-E762
14. Kageyama, K., Bradbury, M. J., Zhao, L. et al. (1999) Urocortin messenger ribonucleic acid: tissue distribution in the rat and regulation in thymus by lipopolysaccharide and glucocorticoids. Endocrinology 140, 5651-5658
15. Zhao, L., Donaldson, C. J., Smith, G. W. and Vale, W. W. (1998) The structures of the mouse and human urocortin genes (Ucn and UCN). Genomics 50, 23-33
16. Mann, D. L. (1999) Mechanisms and models in heart failure: A combinatorial approach. Circulation 100, 999-1008
17. O'Brien, R. J., Loke, I., Squire, I. B., Davies, J. E. and Ng, L. L. (2003) Myotrophin in human heart failure. J. Am. College Cardiol. 42, 719-725