H3K4/H3K9me3 Bivalent Chromatin Domains Targeted by Lineage-Specific DNA Methylation Pauses Adipocyte Differentiation

Molecular Cell

Volumn 60, Issue 4, 2015, Pages 584-596

  Matsumura, Yoshihiro ^a,c   Nakaki, Ryo ^a   Inagaki, Takeshi ^a,c   Yoshida, Ayano ^a,d   Kano, Yuka ^a   Kimura, Hiroshi ^e   Tanaka, Toshiya ^a,b,c   Tsutsumi, Shuichi ^a   Nakao, Mitsuyoshi ^f   Doi, Takefumi ^g   Fukami, Kiyoko ^d   Osborne, Timothy F ^h   Kodama, Tatsuhiko ^b   Aburatani, Hiroyuki ^a,c   Sakai, Juro ^a,c  

^a UNIVERSITY OF TOKYO   (Japan)

^b UNIVERSITY OF TOKYO   (Japan)

^c UNIVERSITY OF TOKYO   (Japan)

^d TOKYO UNIVERSITY OF PHARMACY AND LIFE SCIENCES   (Japan)

^e TOKYO INSTITUTE OF TECHNOLOGY   (Japan)

^f KUMAMOTO UNIVERSITY   (Japan)

^g OSAKA UNIVERSITY   (Japan)

^h BURNHAM INSTITUTE   (United States)

Author keywords

Adipogenesis; Bivalent chromatin domains; DNA methylation; Epigenome; Gene body methylation; H3K27me3; H3K4me3; H3K9me3; Histone methylation; Lineage commitment; RNA polymerase II

Indexed keywords

DEXAMETHASONE; KRUPPEL LIKE FACTOR 2; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA; PROTEIN; RNA POLYMERASE II; SETDB1 PROTEIN; SMALL INTERFERING RNA; TRANSCRIPTION FACTOR GATA 2; UNCLASSIFIED DRUG; WNT1 PROTEIN; WNT5B PROTEIN; CCAAT ENHANCER BINDING PROTEIN; CEBPA PROTEIN, MOUSE; CHROMATIN; HISTONE; HISTONE LYSINE METHYLTRANSFERASE; SETDB1 PROTEIN, MOUSE;

ADIPOCYTE; ADIPOGENESIS; AMINO ACID SUBSTITUTION; ANTIBODY SPECIFICITY; ARTICLE; BINDING SITE; CELL DIFFERENTIATION; CHROMATIN; COMPARATIVE STUDY; CONTROLLED STUDY; DNA BINDING MOTIF; DNA METHYLATION; GENE EXPRESSION; GENE LOCUS; GENE ONTOLOGY; HEK293 CELL LINE; HETEROCHROMATIN; HISTONE ACETYLATION; HISTONE MODIFICATION; HUMAN; HUMAN CELL; IMMUNOBLOTTING; LIPID STORAGE; MESENCHYMAL STEM CELL; MICROARRAY ANALYSIS; NUCLEOSOME; NUCLEOTIDE SEQUENCE; PROADIPOCYTE; PROMOTER REGION; PROTEIN DOMAIN; TRANSCRIPTION ELONGATION; TRANSCRIPTION INITIATION SITE; 3T3 CELL LINE; ANIMAL; CELL CULTURE; CELL LINEAGE; CHEMISTRY; CYTOLOGY; GENETICS; MESENCHYMAL STROMA CELL; METABOLISM; MOUSE; PHYSIOLOGY; PROTEIN TERTIARY STRUCTURE;

3T3 CELLS; ADIPOCYTES; ANIMALS; CCAAT-ENHANCER-BINDING PROTEINS; CELL DIFFERENTIATION; CELL LINEAGE; CELLS, CULTURED; CHROMATIN; DNA METHYLATION; HISTONE-LYSINE N-METHYLTRANSFERASE; HISTONES; MESENCHYMAL STROMAL CELLS; MICE; PPAR GAMMA; PROTEIN STRUCTURE, TERTIARY;

EID: 84947738181     PISSN: 10972765     EISSN: 10974164     Source Type: Journal    
DOI: 10.1016/j.molcel.2015.10.025     Document Type: Article

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