Sesquiterpene lactones inhibit advanced oxidation protein product-induced MCP-1 expression in podocytes via an IKK/NF- B-dependent mechanism

Oxidative Medicine and Cellular Longevity

Volumn 2015, Issue , 2015, Pages

  Zhao, Yan ^a,b   Chen, Si Jia ^a   Wang, Jian Cheng ^a   Niu, Hong Xin ^a   Jia, Qian Qian ^c   Chen, Xiao Wen ^a   Du, Xiao Yan ^a   Lu, Lu ^a   Huang, Bo ^a   Zhang, Quan ^d   Chen, Yue ^d   Long, Hai Bo ^a  

^a SOUTHERN MEDICAL UNIVERSITY   (China)

^b HUBEI UNIVERSITY OF ARTS AND SCIENCE   (China)

^c ZHUMADIAN CENTRAL HOSPITAL   (China)

^d NANKAI UNIVERSITY   (China)

Author keywords

[No Author keywords available]

Indexed keywords

ESTERS; POLYMERASE CHAIN REACTION;

ADVANCED OXIDATION; ANTI-INFLAMMATORY EFFECTS; CHEMOATTRACTANTS; PROTEIN EXPRESSIONS; QUANTITATIVE REAL TIME PCR; SESQUITERPENE LACTONES; TIME DEPENDENT; WESTERN BLOTTING;

PROTEINS;

ADVANCED OXIDATION PROTEIN PRODUCT; ANTIINFLAMMATORY AGENT; CHEMOKINE; I KAPPA B ALPHA; I KAPPA B BETA; MESSENGER RNA; MICHELIOLIDE; MONOCYTE CHEMOTACTIC PROTEIN 1; PARTHENOLIDE; SESQUITERPENE LACTONE; TUBULIN; UNCLASSIFIED DRUG; I KAPPA B; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; LACTONE; NF-KAPPAB INHIBITOR ALPHA; SESQUITERPENE;

ANIMAL CELL; ANIMAL TISSUE; ANTIINFLAMMATORY ACTIVITY; ARTICLE; CELL CULTURE; CONTROLLED STUDY; DIABETIC NEPHROPATHY; DOSE RESPONSE; DRUG MECHANISM; ENZYME LINKED IMMUNOSORBENT ASSAY; KIDNEY DISEASE; MOUSE; NONHUMAN; OXIDATION; PODOCYTE; PROTEIN DEGRADATION; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; QUANTITATIVE ANALYSIS; REAL TIME POLYMERASE CHAIN REACTION; RENAL PROTECTION; WESTERN BLOTTING; ANIMAL; CELL LINE; CHEMISTRY; CYTOLOGY; DRUG EFFECTS; GENE EXPRESSION REGULATION; GENETICS; METABOLISM; PHOSPHORYLATION; SIGNAL TRANSDUCTION;

TANACETUM PARTHENIUM;

ADVANCED OXIDATION PROTEIN PRODUCTS; ANIMALS; CELL LINE; CHEMOKINE CCL2; GENE EXPRESSION REGULATION; I-KAPPA B PROTEINS; LACTONES; MICE; NF-KAPPA B; PHOSPHORYLATION; PODOCYTES; RNA, MESSENGER; SESQUITERPENES; SIGNAL TRANSDUCTION;

EID: 84947649038     PISSN: 19420900     EISSN: 19420994     Source Type: Journal    
DOI: 10.1155/2015/934058     Document Type: Article

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