Sesquiterpene lactones and their derivatives inhibit high glucose-induced NF-κB activation and MCP-1 and TGF-β1 expression in rat mesangial cells

Molecules

Volumn 18, Issue 10, 2013, Pages 13061-13077

  Jia, Qian Qian ^a   Wang, Jian Cheng ^a   Long, Jing ^b   Zhao, Yan ^a   Chen, Si Jia ^a   Zhai, Jia Dai ^b   Wei, Lian Bo ^a   Zhang, Quan ^b   Chen, Yue ^b   Long, Hai Bo ^a  

^a SOUTHERN MEDICAL UNIVERSITY   (China)

^b NANKAI UNIVERSITY   (China)

Author keywords

Deriviative; Diabetic nephropathy; NF B; Sesquiterpene lactone; Synthesis

Indexed keywords

CCL2 PROTEIN, RAT; GLUCOSE; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; LACTONE; MESSENGER RNA; MONOCYTE CHEMOTACTIC PROTEIN 1; REACTIVE OXYGEN METABOLITE; SESQUITERPENE; TGFB1 PROTEIN, RAT; TRANSFORMING GROWTH FACTOR BETA1; PROTEIN BINDING;

ANIMAL; ARTICLE; CELL CULTURE; CELL PROLIFERATION; CELL SURVIVAL; DIABETIC NEPHROPATHY; DRUG EFFECT; DRUG SCREENING; GENE EXPRESSION; GENE EXPRESSION REGULATION; GENETICS; MESANGIUM CELL; METABOLISM; PHYSIOLOGY; PROTEIN BINDING; RAT; SYNTHESIS; DIABETIC NEPHROPATHIES; DRUG EFFECTS;

ANIMALS; CELL PROLIFERATION; CELL SURVIVAL; CELLS, CULTURED; CHEMOKINE CCL2; DIABETIC NEPHROPATHIES; DRUG EVALUATION, PRECLINICAL; GENE EXPRESSION; GENE EXPRESSION REGULATION; GLUCOSE; LACTONES; MESANGIAL CELLS; NF-KAPPA B; PROTEIN BINDING; RATS; REACTIVE OXYGEN SPECIES; RNA, MESSENGER; SESQUITERPENES; TRANSFORMING GROWTH FACTOR BETA1;

EID: 84886638907     PISSN: None     EISSN: 14203049     Source Type: Journal    
DOI: 10.3390/molecules181013061     Document Type: Article

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