Cooperative Dynamics of Intact AMPA and NMDA Glutamate Receptors: Similarities and Subfamily-Specific Differences

Structure

Volumn 23, Issue 9, 2015, Pages 1692-1704

  Dutta, Anindita ^a   Krieger, James ^b   Lee, Ji Young ^a   Garcia Nafria, Javier ^b   Greger, Ingo H ^b   Bahar, Ivet ^a  

^a UNIVERSITY OF PITTSBURGH SCHOOL OF MEDICINE   (United States)

^b MRC LABORATORY OF MOLECULAR BIOLOGY   (United Kingdom)

Author keywords

allosteric events; AMPA and NMDA receptors; conformational dynamics; crosslinking; effector residues; elastic network models; ionotropic glutamate receptors; mutagenesis; NTD LBD coupling; signal transduction

Indexed keywords

AMPA RECEPTOR; DIMER; GLUTAMATE RECEPTOR; IFENPRODIL; ION CHANNEL; IONOTROPIC RECEPTOR; N METHYL DEXTRO ASPARTIC ACID RECEPTOR;

ALLOSTERISM; AMINO TERMINAL SEQUENCE; ARTICLE; CONFORMATIONAL TRANSITION; CONTROLLED STUDY; CRYSTAL STRUCTURE; MEDIATOR; MOLECULAR DYNAMICS; PRIORITY JOURNAL; PROTEIN CONFORMATION; PROTEIN CROSS LINKING; PROTEIN DOMAIN; PROTEIN TRANSPORT; SIGNAL TRANSDUCTION; CHEMISTRY; COMPARATIVE STUDY; HEK293 CELL LINE; HUMAN; METABOLISM; MOLECULAR MODEL; X RAY CRYSTALLOGRAPHY;

ALLOSTERIC REGULATION; CRYSTALLOGRAPHY, X-RAY; HEK293 CELLS; HUMANS; MODELS, MOLECULAR; MOLECULAR DYNAMICS SIMULATION; PROTEIN CONFORMATION; RECEPTORS, AMPA; RECEPTORS, N-METHYL-D-ASPARTATE;

EID: 84947034617     PISSN: 09692126     EISSN: 18784186     Source Type: Journal    
DOI: 10.1016/j.str.2015.07.002     Document Type: Article

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