Impaired cognition and cerebral glucose regulation are associated with astrocyte activation in the parenchyma of metabolically stressed APPswe/PS1dE9 mice

Neurobiology of Aging

Volumn 36, Issue 11, 2015, Pages 2984-2994

  Yeh, Chi Wen ^a   Yeh, Skye Hsin Hsien ^a   Shie, Feng Shiun ^b   Lai, Wen Sung ^c   Liu, Hui Kang ^d,e   Tzeng, Tsai Teng ^a   Tsay, Huey Jen ^a   Shiao, Young Ji ^a,d,e  

^a NATIONAL YANG MING UNIVERSITY   (Taiwan)

^b NATIONAL HEALTH RESEARCH INSTITUTES   (Taiwan)

^c NATIONAL TAIWAN UNIVERSITY   (Taiwan)

^d NATIONAL RESEARCH INSTITUTE OF CHINESE MEDICINE   (Taiwan)

^e TAIPEI MEDICAL UNIVERSITY   (Taiwan)

Author keywords

Alzheimer's disease; Amyloid plaque; Astrocytes; Cerebral glucose regulation; Cognitive dysfunction; Metabolic stresses

Indexed keywords

AMYLOID BETA PROTEIN[1-40]; AMYLOID BETA PROTEIN[1-42]; GLIAL FIBRILLARY ACIDIC PROTEIN; INTERLEUKIN 6; PROTEIN S100B; AMYLOID BETA PROTEIN; GLIAL FIBRILLARY ASTROCYTIC PROTEIN, MOUSE; GLUCOSE; S100B PROTEIN, MOUSE; STREPTOZOCIN;

ALZHEIMER DISEASE; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; ASTROCYTE; CELL ACTIVATION; COGNITIVE DEFECT; CONTROLLED STUDY; DISEASE ASSOCIATION; FEMALE; GLUCOSE METABOLISM; HYPERGLYCEMIA; MALE; MOUSE; NESTING; NEUROPATHOLOGY; NONHUMAN; OBESITY; PRIORITY JOURNAL; PROTEIN EXPRESSION; SPATIAL LEARNING; SPATIAL MEMORY; UPREGULATION; AMYLOID PLAQUE; ANIMAL; BRAIN; COGNITION DISORDERS; METABOLIC SYNDROME X; METABOLISM; MICROVASCULATURE; PATHOLOGY; PHYSIOLOGICAL STRESS; PHYSIOLOGY; TRANSGENIC MOUSE; VASCULARIZATION;

ALZHEIMER DISEASE; AMYLOID BETA-PEPTIDES; ANIMALS; ASTROCYTES; BRAIN; COGNITION DISORDERS; GLIAL FIBRILLARY ACIDIC PROTEIN; GLUCOSE; INTERLEUKIN-6; MALE; METABOLIC SYNDROME X; MICE, TRANSGENIC; MICROVESSELS; OBESITY; PLAQUE, AMYLOID; S100 CALCIUM BINDING PROTEIN BETA SUBUNIT; STREPTOZOCIN; STRESS, PHYSIOLOGICAL;

EID: 84947025276     PISSN: 01974580     EISSN: 15581497     Source Type: Journal    
DOI: 10.1016/j.neurobiolaging.2015.07.022     Document Type: Article

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