-
1
-
-
0035674312
-
Learning and memory in transgenic mice modeling Alzheimer's disease
-
Ashe K.H. Learning and memory in transgenic mice modeling Alzheimer's disease. Learn. Mem. 8 (2001) 301-308
-
(2001)
Learn. Mem.
, vol.8
, pp. 301-308
-
-
Ashe, K.H.1
-
2
-
-
33746041397
-
Cholinergic dysfunction, neuronal damage and axonal loss in TgCRND8 mice
-
Bellucci A., Luccarini I., Scali C., Prosperi C., Giovannini M.G., Pepeu G., and Casamenti F. Cholinergic dysfunction, neuronal damage and axonal loss in TgCRND8 mice. Neurobiol. Dis. 23 (2006) 260-272
-
(2006)
Neurobiol. Dis.
, vol.23
, pp. 260-272
-
-
Bellucci, A.1
Luccarini, I.2
Scali, C.3
Prosperi, C.4
Giovannini, M.G.5
Pepeu, G.6
Casamenti, F.7
-
3
-
-
0030293676
-
Familial Alzheimer's disease-linked presenilin 1 variants elevate Ab1-42/1-40 ratio in vitro and in vivo
-
Borchelt D.R., van Lare J., Lee M.K., Gonzalez V., Jenkins N.A., Copeland N.G., Price D.L., and Sisodia S.S. Familial Alzheimer's disease-linked presenilin 1 variants elevate Ab1-42/1-40 ratio in vitro and in vivo. Neuron 17 (1996) 1005-1013
-
(1996)
Neuron
, vol.17
, pp. 1005-1013
-
-
Borchelt, D.R.1
van Lare, J.2
Lee, M.K.3
Gonzalez, V.4
Jenkins, N.A.5
Copeland, N.G.6
Price, D.L.7
Sisodia, S.S.8
-
4
-
-
0030833055
-
Accelerated amyloid deposition in the brains of transgenic mice coexpressing mutant presenilin 1 and amyloid precursor proteins
-
Borchelt D.R., Thinakaran G., Eckman C.B., Lee M.K., Davenport F., Ratovitsky T., Prada C.M., Kim G., Seekins S., Yager D., Slunt H.H., Wang R., Seeger M., Levey A.I., Gandy S.E., Copeland N.G., Jenkins N.A., Price D.L., Younkin S.G., and Sisodia S.S. Accelerated amyloid deposition in the brains of transgenic mice coexpressing mutant presenilin 1 and amyloid precursor proteins. Neuron 19 (1997) 939-945
-
(1997)
Neuron
, vol.19
, pp. 939-945
-
-
Borchelt, D.R.1
Thinakaran, G.2
Eckman, C.B.3
Lee, M.K.4
Davenport, F.5
Ratovitsky, T.6
Prada, C.M.7
Kim, G.8
Seekins, S.9
Yager, D.10
Slunt, H.H.11
Wang, R.12
Seeger, M.13
Levey, A.I.14
Gandy, S.E.15
Copeland, N.G.16
Jenkins, N.A.17
Price, D.L.18
Younkin, S.G.19
Sisodia, S.S.20
more..
-
5
-
-
52249115856
-
Clusters of hyperactive neurons near amyloid plaques in a mouse model of Alzheimer's disease
-
Busche M.A., Eichhoff G., Adelsberger H., Abramowski D., Wiederhold K.H., Haass C., Staufenbiel M., Konnerth A., and Garaschuk O. Clusters of hyperactive neurons near amyloid plaques in a mouse model of Alzheimer's disease. Science 321 (2008) 1686-1699
-
(2008)
Science
, vol.321
, pp. 1686-1699
-
-
Busche, M.A.1
Eichhoff, G.2
Adelsberger, H.3
Abramowski, D.4
Wiederhold, K.H.5
Haass, C.6
Staufenbiel, M.7
Konnerth, A.8
Garaschuk, O.9
-
6
-
-
36849045250
-
Progesterone and estrogen regulate Alzheimer-like neuropathology in female 3xTg-AD mice.
-
Carroll J.C., Rosario E.R., Chang L., Stanczyk F.Z., Oddo S., LaFerla F.M., and Pike C.J. Progesterone and estrogen regulate Alzheimer-like neuropathology in female 3xTg-AD mice. J. Neurosci. 27 (2007) 13357-13365
-
(2007)
J. Neurosci.
, vol.27
, pp. 13357-13365
-
-
Carroll, J.C.1
Rosario, E.R.2
Chang, L.3
Stanczyk, F.Z.4
Oddo, S.5
LaFerla, F.M.6
Pike, C.J.7
-
7
-
-
0034523749
-
Neurobehavioral and neuropsychiatric symptoms in Alzheimer's disease
-
Chung J.A., and Cummings J.L. Neurobehavioral and neuropsychiatric symptoms in Alzheimer's disease. Neurol. Clin. 18 (2000) 829-846
-
(2000)
Neurol. Clin.
, vol.18
, pp. 829-846
-
-
Chung, J.A.1
Cummings, J.L.2
-
8
-
-
34548738209
-
Age-dependent sexual dimorphism in cognition and stress response in the 3xTg-AD mice
-
Clinton L.K., Billings L.M., Green K.N., Caccamo A., Ngo J., Oddo S., McGaugh J.L., and LaFerla F.M. Age-dependent sexual dimorphism in cognition and stress response in the 3xTg-AD mice. Neurobiol. Dis. 28 (2007) 76-82
-
(2007)
Neurobiol. Dis.
, vol.28
, pp. 76-82
-
-
Clinton, L.K.1
Billings, L.M.2
Green, K.N.3
Caccamo, A.4
Ngo, J.5
Oddo, S.6
McGaugh, J.L.7
LaFerla, F.M.8
-
9
-
-
40849136379
-
Age-dependent and -independent behavioral deficits in Tg2576 mice
-
Deacon R.M.J., Cholerton L.L., Talbot K., Nair-Roberts R.G., Sanderson D.J., Romberg C., Koros E., Bornemann K.D., and Rawlins J.N.P. Age-dependent and -independent behavioral deficits in Tg2576 mice. Behav. Brain Res. 189 (2008) 126-138
-
(2008)
Behav. Brain Res.
, vol.189
, pp. 126-138
-
-
Deacon, R.M.J.1
Cholerton, L.L.2
Talbot, K.3
Nair-Roberts, R.G.4
Sanderson, D.J.5
Romberg, C.6
Koros, E.7
Bornemann, K.D.8
Rawlins, J.N.P.9
-
10
-
-
61449189852
-
Cognitive and non-cognitive behaviors in an APPswe/PS1 bigenic model of Alzheimer's disease
-
Filali M., Lalonde R., and Rivest S. Cognitive and non-cognitive behaviors in an APPswe/PS1 bigenic model of Alzheimer's disease. Genes Brain Behav. 8 (2009) 143-148
-
(2009)
Genes Brain Behav.
, vol.8
, pp. 143-148
-
-
Filali, M.1
Lalonde, R.2
Rivest, S.3
-
11
-
-
0033056242
-
Behavioral syndromes in Alzheimer's disease: description and correlates
-
Frisoni G.B., Rozzini L., Gozetti A., Binetti G., Zanetti O., Bianchetti A., Trabucchi M., and Cummings J.L. Behavioral syndromes in Alzheimer's disease: description and correlates. Dement. Geriatr. Cogn. Disord. 10 (1999) 130-138
-
(1999)
Dement. Geriatr. Cogn. Disord.
, vol.10
, pp. 130-138
-
-
Frisoni, G.B.1
Rozzini, L.2
Gozetti, A.3
Binetti, G.4
Zanetti, O.5
Bianchetti, A.6
Trabucchi, M.7
Cummings, J.L.8
-
12
-
-
33646480747
-
Reversal of Alzheimer's-like pathology and behavior in human APP transgenic mice by mutation of Asp664
-
Galvan V., Gorostiza O.F., Banwait S., Ataie M., Logvinova A.V., Sitaraman S., Carlson E., Sagi S.A., Chevallier N., Jin K., Greenberg D.A., and Bredesen D.E. Reversal of Alzheimer's-like pathology and behavior in human APP transgenic mice by mutation of Asp664. Proc. Natl. Acad. Sci. U. S. A. 103 (2006) 7130-7135
-
(2006)
Proc. Natl. Acad. Sci. U. S. A.
, vol.103
, pp. 7130-7135
-
-
Galvan, V.1
Gorostiza, O.F.2
Banwait, S.3
Ataie, M.4
Logvinova, A.V.5
Sitaraman, S.6
Carlson, E.7
Sagi, S.A.8
Chevallier, N.9
Jin, K.10
Greenberg, D.A.11
Bredesen, D.E.12
-
13
-
-
0031914718
-
Accelerated Alzheimer-type phenotype in transgenic mice carrying both mutant amyloid precursor protein and presenilin transgenes
-
Holcomb L., Gordon M.N., McGowan E., Yu X., Benkowic S., Jantzen P., Wright K., Saad I., Mueller R., Morgan D., Sanders S., Zehr C., O'Campo K., Hardy J., Prada C.-M., Eckman C., Younkin S., Hsiao K., and Duff K. Accelerated Alzheimer-type phenotype in transgenic mice carrying both mutant amyloid precursor protein and presenilin transgenes. Nat. Med. 4 (1998) 97-100
-
(1998)
Nat. Med.
, vol.4
, pp. 97-100
-
-
Holcomb, L.1
Gordon, M.N.2
McGowan, E.3
Yu, X.4
Benkowic, S.5
Jantzen, P.6
Wright, K.7
Saad, I.8
Mueller, R.9
Morgan, D.10
Sanders, S.11
Zehr, C.12
O'Campo, K.13
Hardy, J.14
Prada, C.-M.15
Eckman, C.16
Younkin, S.17
Hsiao, K.18
Duff, K.19
-
14
-
-
0032756213
-
Behavioral changes in transgenic mice expressing both amyloid precursor protein and presenilin-1 mutations: lack of association with amyloid deposits
-
Holcomb L.A., Gordon M.N., Jantzen P., Hsiao K., Duff K., and Morgan D. Behavioral changes in transgenic mice expressing both amyloid precursor protein and presenilin-1 mutations: lack of association with amyloid deposits. Behav. Genet. 29 (1999) 177-185
-
(1999)
Behav. Genet.
, vol.29
, pp. 177-185
-
-
Holcomb, L.A.1
Gordon, M.N.2
Jantzen, P.3
Hsiao, K.4
Duff, K.5
Morgan, D.6
-
15
-
-
33745808762
-
Neprilysin-sensitive synapse-associated amyloid-beta peptide oligomers impair neuronal plasticity and cognitive function
-
Huang S.M., Mouri A., Kokubo H., Nakajima R., Suemoto T., Higuchi M., Staufenbiel M., Noda Y., Yamaguchi H., Nabeshima T., Saido T.C., and Iwata N. Neprilysin-sensitive synapse-associated amyloid-beta peptide oligomers impair neuronal plasticity and cognitive function. J. Biol. Chem. 281 (2006) 17941-17951
-
(2006)
J. Biol. Chem.
, vol.281
, pp. 17941-17951
-
-
Huang, S.M.1
Mouri, A.2
Kokubo, H.3
Nakajima, R.4
Suemoto, T.5
Higuchi, M.6
Staufenbiel, M.7
Noda, Y.8
Yamaguchi, H.9
Nabeshima, T.10
Saido, T.C.11
Iwata, N.12
-
16
-
-
12144286749
-
Decreased level of brain acetylcholine and memory disturbance in APPsw mice
-
Ikarashi Y., Harigaya Y., Tomidokoro Y., Kanai M., Ikeda M., Matsubara E., Kawarabayashi T., Kuribara H., Younkin S.G., Maruyama Y., and Shoji M. Decreased level of brain acetylcholine and memory disturbance in APPsw mice. Neurobiol. Aging 25 (2004) 483-490
-
(2004)
Neurobiol. Aging
, vol.25
, pp. 483-490
-
-
Ikarashi, Y.1
Harigaya, Y.2
Tomidokoro, Y.3
Kanai, M.4
Ikeda, M.5
Matsubara, E.6
Kawarabayashi, T.7
Kuribara, H.8
Younkin, S.G.9
Maruyama, Y.10
Shoji, M.11
-
17
-
-
0037088956
-
Behavioral characterization of the Tg2576 transgenic model of Alzheimer's disease through 19 months
-
King D.L., and Arendash G.W. Behavioral characterization of the Tg2576 transgenic model of Alzheimer's disease through 19 months. Physiol. Behav. 5 (2002) 627-642
-
(2002)
Physiol. Behav.
, vol.5
, pp. 627-642
-
-
King, D.L.1
Arendash, G.W.2
-
18
-
-
0021744034
-
Functions of the frontal cortex of the rat: a comparative review
-
Kolb B. Functions of the frontal cortex of the rat: a comparative review. Brain Res. 320 (1984) 65-98
-
(1984)
Brain Res.
, vol.320
, pp. 65-98
-
-
Kolb, B.1
-
19
-
-
0036161518
-
The neurobiological basis of spontaneous alternation
-
Lalonde R. The neurobiological basis of spontaneous alternation. Neurosci. Biobehav. Rev. 26 (2002) 91-104
-
(2002)
Neurosci. Biobehav. Rev.
, vol.26
, pp. 91-104
-
-
Lalonde, R.1
-
21
-
-
33645038471
-
A specific amyloid-β protein assembly in the brain impairs memory
-
Lesné S., Koh M.T., Kotilinek L., Kayed R., Glabe C.G., Yang A., Gallagher M., and Ashe K.H. A specific amyloid-β protein assembly in the brain impairs memory. Nature 440 (2006) 352-357
-
(2006)
Nature
, vol.440
, pp. 352-357
-
-
Lesné, S.1
Koh, M.T.2
Kotilinek, L.3
Kayed, R.4
Glabe, C.G.5
Yang, A.6
Gallagher, M.7
Ashe, K.H.8
-
23
-
-
0036174969
-
The effects of long-term treatment with metrifonate, a cholinesterase inhibitor, on cholinergic activity, amyloid pathology, and cognitive function in APP and PS1 doubly transgenic mice
-
Liu L., Ikonen S., Heikkinen T., Tapiola T., van Groen T., and Tanila H. The effects of long-term treatment with metrifonate, a cholinesterase inhibitor, on cholinergic activity, amyloid pathology, and cognitive function in APP and PS1 doubly transgenic mice. Exp. Neurol. 173 (2002) 196-204
-
(2002)
Exp. Neurol.
, vol.173
, pp. 196-204
-
-
Liu, L.1
Ikonen, S.2
Heikkinen, T.3
Tapiola, T.4
van Groen, T.5
Tanila, H.6
-
24
-
-
33750028699
-
Soluble Aβ and cognitive function in aged F-344 rats and Tg2576 mice
-
Lindner M.D., Hogan J.B., Krause R.G., Machet F., Bourin C., Hodges Jr. D.B., Corsa J.A., Barten D.M., Toyn J.H., Stock D.A., Rose G.M., and Gribkoff V.K. Soluble Aβ and cognitive function in aged F-344 rats and Tg2576 mice. Behav. Brain Res. 173 (2006) 62-75
-
(2006)
Behav. Brain Res.
, vol.173
, pp. 62-75
-
-
Lindner, M.D.1
Hogan, J.B.2
Krause, R.G.3
Machet, F.4
Bourin, C.5
Hodges Jr., D.B.6
Corsa, J.A.7
Barten, D.M.8
Toyn, J.H.9
Stock, D.A.10
Rose, G.M.11
Gribkoff, V.K.12
-
25
-
-
0037118879
-
Elevated levels of Ab1-40 and Ab1-42 do not alter the binding sites of nicotinic receptor subtypes in the brain of APPswe and PS1 double transgenic mice
-
Marutle A., Unger C., Hellstrom-Lindahl E., Wang J., Puolivali J., Tanila H., Nordberg A., and Zhang X. Elevated levels of Ab1-40 and Ab1-42 do not alter the binding sites of nicotinic receptor subtypes in the brain of APPswe and PS1 double transgenic mice. Neurosci. Lett. 328 (2002) 269-272
-
(2002)
Neurosci. Lett.
, vol.328
, pp. 269-272
-
-
Marutle, A.1
Unger, C.2
Hellstrom-Lindahl, E.3
Wang, J.4
Puolivali, J.5
Tanila, H.6
Nordberg, A.7
Zhang, X.8
-
26
-
-
33749521100
-
Intraneuronal β-amyloid aggregates, neurodegeneration, and neuron loss in transgenic mice with five familial Alzheimer's disease mutations: potential factors in amyloid plaque formation
-
Oakley H., Cole S.L., Logan S., Maus E., Shao P., Craft J., Guillozet-Bongaarts A., Ohno M., Disterhoft J., Van Eldik L., Berry R., and Vassar R. Intraneuronal β-amyloid aggregates, neurodegeneration, and neuron loss in transgenic mice with five familial Alzheimer's disease mutations: potential factors in amyloid plaque formation. J. Neurosci. 26 (2006) 10129-10140
-
(2006)
J. Neurosci.
, vol.26
, pp. 10129-10140
-
-
Oakley, H.1
Cole, S.L.2
Logan, S.3
Maus, E.4
Shao, P.5
Craft, J.6
Guillozet-Bongaarts, A.7
Ohno, M.8
Disterhoft, J.9
Van Eldik, L.10
Berry, R.11
Vassar, R.12
-
27
-
-
60549096278
-
Limited impact of social isolation on Alzheimer-like symptoms in a triple transgenic model
-
Pietropaolo S., Sun Y., Li R., Brana C., Feldon J., and Yee B.K. Limited impact of social isolation on Alzheimer-like symptoms in a triple transgenic model. Behav. Neurosci. 123 (2009) 181-195
-
(2009)
Behav. Neurosci.
, vol.123
, pp. 181-195
-
-
Pietropaolo, S.1
Sun, Y.2
Li, R.3
Brana, C.4
Feldon, J.5
Yee, B.K.6
-
28
-
-
0036235633
-
Hippocampal Ab42 levels correlate with spatial memory deficit in APP and PS1 double transgenic mice
-
Puoliväli J., Wang J., Heikkinen T., Heikkilä M., Tapiola T., van Groen T., and Tanila H. Hippocampal Ab42 levels correlate with spatial memory deficit in APP and PS1 double transgenic mice. Neurobiol. Dis. 9 (2002) 339-347
-
(2002)
Neurobiol. Dis.
, vol.9
, pp. 339-347
-
-
Puoliväli, J.1
Wang, J.2
Heikkinen, T.3
Heikkilä, M.4
Tapiola, T.5
van Groen, T.6
Tanila, H.7
-
29
-
-
0141707862
-
PS2APP transgenic mice, coexpressing hPS2mut and hAPPswe, show age-related cognitive deficits associated with discrete brain amyloid deposition and inflammation
-
Richards J.G., Higgins G.A., Ouagazzal A.-M., Ozmen L., Kew J.N.C., Bohrmann B., Malherbe P., Brockhaus M., Loetscher H., Czech C., Huber G., Bluethmann H., Jacobsen H., and Kemp J.A. PS2APP transgenic mice, coexpressing hPS2mut and hAPPswe, show age-related cognitive deficits associated with discrete brain amyloid deposition and inflammation. J. Neurosci. 23 (2003) 8989-9003
-
(2003)
J. Neurosci.
, vol.23
, pp. 8989-9003
-
-
Richards, J.G.1
Higgins, G.A.2
Ouagazzal, A.-M.3
Ozmen, L.4
Kew, J.N.C.5
Bohrmann, B.6
Malherbe, P.7
Brockhaus, M.8
Loetscher, H.9
Czech, C.10
Huber, G.11
Bluethmann, H.12
Jacobsen, H.13
Kemp, J.A.14
-
30
-
-
10744230072
-
Ultrastructural and behavioural changes precede amyloid deposition in a transgenic model of Alzheimer's disease
-
Richardson J.C., Kendal C.E., Anderson R., Priest F., Gower E., Soden P., Gray R., Topps S., Howlett D.R., Lavender D., Clarke N.J., Barnes J.C., Haworth R., Stewart M.G., and Rupniak H.T.R. Ultrastructural and behavioural changes precede amyloid deposition in a transgenic model of Alzheimer's disease. Neuroscience 122 (2003) 213-228
-
(2003)
Neuroscience
, vol.122
, pp. 213-228
-
-
Richardson, J.C.1
Kendal, C.E.2
Anderson, R.3
Priest, F.4
Gower, E.5
Soden, P.6
Gray, R.7
Topps, S.8
Howlett, D.R.9
Lavender, D.10
Clarke, N.J.11
Barnes, J.C.12
Haworth, R.13
Stewart, M.G.14
Rupniak, H.T.R.15
-
31
-
-
0032886820
-
Use of SHIRPA and discriminant analysis to characterise marked differences in the behavioural phenotype of six inbred mouse strains
-
Rogers D.C., Jones D.N.C., Nelson P.R., Jones C.M., Quilter C.A., Robinson T.L., and Hagan J.J. Use of SHIRPA and discriminant analysis to characterise marked differences in the behavioural phenotype of six inbred mouse strains. Behav. Brain Res. 105 (1999) 207-217
-
(1999)
Behav. Brain Res.
, vol.105
, pp. 207-217
-
-
Rogers, D.C.1
Jones, D.N.C.2
Nelson, P.R.3
Jones, C.M.4
Quilter, C.A.5
Robinson, T.L.6
Hagan, J.J.7
-
32
-
-
0038755949
-
Normal cognitive behavior in two distinct congenic lines of transgenic mice hyperexpresing APPSWE
-
Savonenko A.V., Xu G.M., Price D.L., Borchelt D.R., and Markowska A.L. Normal cognitive behavior in two distinct congenic lines of transgenic mice hyperexpresing APPSWE. Neurobiol. Dis. 12 (2003) 194-211
-
(2003)
Neurobiol. Dis.
, vol.12
, pp. 194-211
-
-
Savonenko, A.V.1
Xu, G.M.2
Price, D.L.3
Borchelt, D.R.4
Markowska, A.L.5
-
33
-
-
0346848902
-
Gender differences in the amount and deposition of amyloidb in APPswe and PS1 double transgenic mice
-
Wang J., Tanila H., Puoliväli J., Kadish I., and van Groen T. Gender differences in the amount and deposition of amyloidb in APPswe and PS1 double transgenic mice. Neurobiol. Dis. 14 (2003) 318-327
-
(2003)
Neurobiol. Dis.
, vol.14
, pp. 318-327
-
-
Wang, J.1
Tanila, H.2
Puoliväli, J.3
Kadish, I.4
van Groen, T.5
-
34
-
-
42649134163
-
Deficits in working memory and motor performance in the APP/PS1ki mouse model for Alzheimer's disease
-
Wirths O., Breyhan H., Schäfer S., Roth C., and Bayer T.A. Deficits in working memory and motor performance in the APP/PS1ki mouse model for Alzheimer's disease. Neurobiol. Aging 29 (2008) 891-901
-
(2008)
Neurobiol. Aging
, vol.29
, pp. 891-901
-
-
Wirths, O.1
Breyhan, H.2
Schäfer, S.3
Roth, C.4
Bayer, T.A.5
|