-
1
-
-
78651356190
-
Phytic acid as a potential treatment for Alzheimer's pathology: Evidence from animal and in vitro models
-
Anekonda, T. S., Wadsworth, T. L., Sabin, R., Frahler, K., Harris, C., Petriko, B., et al. (2011). Phytic acid as a potential treatment for Alzheimer's pathology: evidence from animal and in vitro models. J Alzheimers Dis 23, 21-35.
-
(2011)
J Alzheimers Dis
, vol.23
, pp. 21-35
-
-
Anekonda, T.S.1
Wadsworth, T.L.2
Sabin, R.3
Frahler, K.4
Harris, C.5
Petriko, B.6
-
2
-
-
77749270474
-
Novel therapeutics for Alzheimer's disease: An update
-
Bonda, D. J., Lee, H.-P., Lee, H.-G., Friedlich, A. L., Perry, G., Zhu, X., et al. (2010). Novel therapeutics for Alzheimer's disease: An update. Curr Opin Drug Discov Dev 13, 235.
-
(2010)
Curr Opin Drug Discov Dev
, vol.13
, pp. 235
-
-
Bonda, D.J.1
Lee, H.-P.2
Lee, H.-G.3
Friedlich, A.L.4
Perry, G.5
Zhu, X.6
-
3
-
-
84878631905
-
Induction of autophagy by a novel small molecule improves abeta pathology and ameliorates cognitive deficits
-
Chu, C., Zhang, X., Ma, W., Li, L., Wang, W., Shang, L., et al. (2013). Induction of autophagy by a novel small molecule improves abeta pathology and ameliorates cognitive deficits. PLoS One 8, e65367.
-
(2013)
PLoS One
, vol.8
, pp. e65367
-
-
Chu, C.1
Zhang, X.2
Ma, W.3
Li, L.4
Wang, W.5
Shang, L.6
-
4
-
-
69449100293
-
Impaired autophagosomelysosome fusion in the pathogenesis of pancreatitis
-
Fortunato, F., and Kroemer, G. (2009). Impaired autophagosomelysosome fusion in the pathogenesis of pancreatitis. Autophagy 5, 850-853.
-
(2009)
Autophagy
, vol.5
, pp. 850-853
-
-
Fortunato, F.1
Kroemer, G.2
-
5
-
-
44049108170
-
Loss of microRNA cluster miR-29a/b-1 in sporadic Alzheimer's disease correlates with increased BACE1/beta-secretase expression
-
Hebert, S. S., Horre, K., Nicolai, L., Papadopoulou, A. S., Mandemakers, W., Silahtaroglu, A. N., et al. (2008). Loss of microRNA cluster miR-29a/b-1 in sporadic Alzheimer's disease correlates with increased BACE1/beta-secretase expression. Proc Natl Acad Sci U S A 105, 6415-6420.
-
(2008)
Proc Natl Acad Sci U S A
, vol.105
, pp. 6415-6420
-
-
Hebert, S.S.1
Horre, K.2
Nicolai, L.3
Papadopoulou, A.S.4
Mandemakers, W.5
Silahtaroglu, A.N.6
-
6
-
-
84927933879
-
Heme oxygenase-1 protects against Alzheimer's amyloid-beta(1-42)-induced toxicity via carbon monoxide production
-
Hettiarachchi, N., Dallas, M., Al-Owais, M., Griffiths, H., Hooper, N., Scragg, J., et al. (2014). Heme oxygenase-1 protects against Alzheimer's amyloid-beta(1-42)-induced toxicity via carbon monoxide production. Cell Death Dis 5, e1569.
-
(2014)
Cell Death Dis
, vol.5
, pp. e1569
-
-
Hettiarachchi, N.1
Dallas, M.2
Al-Owais, M.3
Griffiths, H.4
Hooper, N.5
Scragg, J.6
-
7
-
-
1642555780
-
Mutant presenilins specifically elevate the levels of the 42 residue beta-amyloid peptide in vivo: Evidence for augmentation of a 42-specific gamma secretase
-
Jankowsky, J. L., Fadale, D. J., Anderson, J., Xu, G. M., Gonzales, V., Jenkins, N. A., et al. (2004). Mutant presenilins specifically elevate the levels of the 42 residue beta-amyloid peptide in vivo: evidence for augmentation of a 42-specific gamma secretase. Hum Mol Genet 13, 159-170.
-
(2004)
Hum Mol Genet
, vol.13
, pp. 159-170
-
-
Jankowsky, J.L.1
Fadale, D.J.2
Anderson, J.3
Xu, G.M.4
Gonzales, V.5
Jenkins, N.A.6
-
8
-
-
0031746979
-
A detergent-insoluble membrance compartment contains Ab in vivo
-
Lee, S.-J., Liyanage, U., Bickel, P. E., Xia, W., Lansbury, P. T., and Kosik, K. S. (1998). A detergent-insoluble membrance compartment contains Ab in vivo. Nat Med 4, 730-734.
-
(1998)
Nat Med
, vol.4
, pp. 730-734
-
-
Lee, S.-J.1
Liyanage, U.2
Bickel, P.E.3
Xia, W.4
Lansbury, P.T.5
Kosik, K.S.6
-
9
-
-
84896301845
-
Accumulation of amyloid-likeAbeta1-42 inAEL(autophagy-endosomallysosomal) vesicles: Potential implications for plaque biogenesis
-
Ling, D., Magallanes, M., and Salvaterra, P. M. (2014). Accumulation of amyloid-likeAbeta1-42 inAEL(autophagy-endosomallysosomal) vesicles: Potential implications for plaque biogenesis. ASN Neuro 6, pii: e00139, doi: 10. 1042/AN20130044.
-
(2014)
ASN Neuro
, vol.6
, pp. e00139
-
-
Ling, D.1
Magallanes, M.2
Salvaterra, P.M.3
-
10
-
-
70350460031
-
Protein carbonylation: Avoiding pitfalls in the 2, 4-dinitrophenylhydrazine assay
-
Luo, S., and Wehr, N. B. (2009). Protein carbonylation: Avoiding pitfalls in the 2, 4-dinitrophenylhydrazine assay. Redox Rep 14, 159-166.
-
(2009)
Redox Rep
, vol.14
, pp. 159-166
-
-
Luo, S.1
Wehr, N.B.2
-
11
-
-
80053243942
-
Inducing autophagy by rapamycin before, but not after, the formation of plaques and tangles ameliorates cognitive deficits
-
Majumder, S., Richardson, A., Strong, R., and Oddo, S. (2011). Inducing autophagy by rapamycin before, but not after, the formation of plaques and tangles ameliorates cognitive deficits. PLoS One 6, e25416.
-
(2011)
PLoS One
, vol.6
, pp. e25416
-
-
Majumder, S.1
Richardson, A.2
Strong, R.3
Oddo, S.4
-
12
-
-
39849109338
-
Autophagy fights disease through cellular selfdigestion
-
Mizushima, N., Levine, B., Cuervo, A. M., and Klionsky, D. J. (2008). Autophagy fights disease through cellular selfdigestion. Nature 451, 1069-1075.
-
(2008)
Nature
, vol.451
, pp. 1069-1075
-
-
Mizushima, N.1
Levine, B.2
Cuervo, A.M.3
Klionsky, D.J.4
-
13
-
-
38349046973
-
Autophagy, amyloidogenesis and Alzheimer disease
-
Nixon, R. A. (2007). Autophagy, amyloidogenesis and Alzheimer disease. J Cell Sci 120, 4081-4091.
-
(2007)
J Cell Sci
, vol.120
, pp. 4081-4091
-
-
Nixon, R.A.1
-
14
-
-
79955969705
-
Autophagy failure in Alzheimer's disease-locating the primary defect
-
Nixon, R. A., and Yang, D.-S. (2011). Autophagy failure in Alzheimer's disease-locating the primary defect. Neurobiol Dis 43, 38-45.
-
(2011)
Neurobiol Dis
, vol.43
, pp. 38-45
-
-
Nixon, R.A.1
Yang, D.-S.2
-
15
-
-
7044249860
-
Determination of the thiol redox state of organisms: New oxidative stress indicators
-
Patsoukis, N., and Georgiou, C. D. (2004). Determination of the thiol redox state of organisms: new oxidative stress indicators. Anal Bioanal Chem 378, 1783-1792.
-
(2004)
Anal Bioanal Chem
, vol.378
, pp. 1783-1792
-
-
Patsoukis, N.1
Georgiou, C.D.2
-
16
-
-
84916928995
-
Selective clearance of aberrant tau proteins and rescue of neurotoxicity by transcription factor EB
-
Polito, V. A., Li, H., Martini-Stoica, H., Wang, B., Yang, L., Xu, Y., et al. (2014). Selective clearance of aberrant tau proteins and rescue of neurotoxicity by transcription factor EB. EMBO Mol Med 6, 1142-1160.
-
(2014)
EMBO Mol Med
, vol.6
, pp. 1142-1160
-
-
Polito, V.A.1
Li, H.2
Martini-Stoica, H.3
Wang, B.4
Yang, L.5
Xu, Y.6
-
17
-
-
84862539692
-
The transcription factor TFEB links mTORC1 signaling to transcriptional control of lysosome homeostasis
-
Roczniak-Ferguson, A., Petit, C. S., Froehlich, F., Qian, S., Ky, J., Angarola, B., et al. (2012). The transcription factor TFEB links mTORC1 signaling to transcriptional control of lysosome homeostasis. Sci Signal 5, ra42.
-
(2012)
Sci Signal
, vol.5
, pp. ra42
-
-
Roczniak-Ferguson, A.1
Petit, C.S.2
Froehlich, F.3
Qian, S.4
Ky, J.5
Angarola, B.6
-
18
-
-
84858269210
-
Molecular network of microRNA targets in Alzheimer's disease brains
-
Satoh, J. (2012). Molecular network of microRNA targets in Alzheimer's disease brains. Exp Neurol 235, 436-446.
-
(2012)
Exp Neurol
, vol.235
, pp. 436-446
-
-
Satoh, J.1
-
19
-
-
80955177196
-
TFEB links autophagy to lysosomal biogenesis
-
Settembre, C., Di Malta, C., Polito, V. A., Garcia Arencibia, M., Vetrini, F., Erdin, S., et al. (2011). TFEB links autophagy to lysosomal biogenesis. Science 332, 1429-1433.
-
(2011)
Science
, vol.332
, pp. 1429-1433
-
-
Settembre, C.1
Di Malta, C.2
Polito, V.A.3
Garcia Arencibia, M.4
Vetrini, F.5
Erdin, S.6
-
20
-
-
84857997408
-
A lysosome-to-nucleus signalling mechanism senses and regulates the lysosome via mTOR and TFEB
-
Settembre, C., Zoncu, R., Medina, D. L., Vetrini, F., Erdin, S., Huynh, T., et al. (2012). A lysosome-to-nucleus signalling mechanism senses and regulates the lysosome via mTOR and TFEB. EMBO J 31, 1095-1108.
-
(2012)
EMBO J
, vol.31
, pp. 1095-1108
-
-
Settembre, C.1
Zoncu, R.2
Medina, D.L.3
Vetrini, F.4
Erdin, S.5
Huynh, T.6
-
21
-
-
84890048084
-
Nicotinamide treatment reduces the levels of oxidative stress, apoptosis, and PARP-1 activity in Abeta(1-42)-induced rat model of Alzheimer's disease
-
Turunc Bayrakdar, E., Uyanikgil, Y., Kanit, L., Koylu, E., and Yalcin, A. (2014). Nicotinamide treatment reduces the levels of oxidative stress, apoptosis, and PARP-1 activity in Abeta(1-42)-induced rat model of Alzheimer's disease. Free Radic Res 48, 146-158.
-
(2014)
Free Radic Res
, vol.48
, pp. 146-158
-
-
Turunc Bayrakdar, E.1
Uyanikgil, Y.2
Kanit, L.3
Koylu, E.4
Yalcin, A.5
-
22
-
-
79451474371
-
Patterns of microRNA expression in normal and early Alzheimer's disease human temporal cortex: White matter versus gray matter
-
Wang, W. X., Huang, Q., Hu, Y., Stromberg, A. J., and Nelson, P. T. (2011). Patterns of microRNA expression in normal and early Alzheimer's disease human temporal cortex: white matter versus gray matter. Acta Neuropathol 121, 193-205.
-
(2011)
Acta Neuropathol
, vol.121
, pp. 193-205
-
-
Wang, W.X.1
Huang, Q.2
Hu, Y.3
Stromberg, A.J.4
Nelson, P.T.5
-
23
-
-
38749095507
-
The expression of microRNA miR-107 decreases early in Alzheimer's disease and may accelerate disease progression through regulation of b-site amyloid precursor protein-cleaving enzyme 1
-
Wang, W.-X., Rajeev, B. W., Stromberg, A. J., Ren, N., Tang, G., Huang, Q., et al. (2008). The expression of microRNA miR-107 decreases early in Alzheimer's disease and may accelerate disease progression through regulation of b-site amyloid precursor protein-cleaving enzyme 1. J Neurosci 28, 1213-1223.
-
(2008)
J Neurosci
, vol.28
, pp. 1213-1223
-
-
Wang, W.-X.1
Rajeev, B.W.2
Stromberg, A.J.3
Ren, N.4
Tang, G.5
Huang, Q.6
-
24
-
-
84879950983
-
Monitoring autophagy in the treatment of protein aggregate diseases: Steps toward identifying autophagic biomarkers
-
Weihl, C. C. (2013). Monitoring autophagy in the treatment of protein aggregate diseases: steps toward identifying autophagic biomarkers. Neurotherapeutics 10, 383-390.
-
(2013)
Neurotherapeutics
, vol.10
, pp. 383-390
-
-
Weihl, C.C.1
-
25
-
-
77954116814
-
Autophagy gone awry in neurodegenerative diseases
-
Wong, E., and Cuervo, A. M. (2010). Autophagy gone awry in neurodegenerative diseases. Nat Neurosci 13, 805-811.
-
(2010)
Nat Neurosci
, vol.13
, pp. 805-811
-
-
Wong, E.1
Cuervo, A.M.2
-
26
-
-
84904354536
-
Enhancing astrocytic lysosome biogenesis facilitates Abeta clearance and attenuates amyloid plaque pathogenesis
-
Xiao, Q., Yan, P., Ma, X., Liu, H., Perez, R., Zhu, A., et al. (2014). Enhancing astrocytic lysosome biogenesis facilitates Abeta clearance and attenuates amyloid plaque pathogenesis. J Neurosci 34, 9607-9620.
-
(2014)
J Neurosci
, vol.34
, pp. 9607-9620
-
-
Xiao, Q.1
Yan, P.2
Ma, X.3
Liu, H.4
Perez, R.5
Zhu, A.6
-
27
-
-
84922368172
-
Defective macroautophagic turnover of brain lipids in the TgCRND8 Alzheimer mouse model: Prevention by correcting lysosomal proteolytic deficits
-
Yang, D. S., Stavrides, P., Saito, M., Kumar, A., Rodriguez-Navarro, J. A., Pawlik, M., et al. (2014). Defective macroautophagic turnover of brain lipids in the TgCRND8 Alzheimer mouse model: Prevention by correcting lysosomal proteolytic deficits. Brain 137, 3300-3318.
-
(2014)
Brain
, vol.137
, pp. 3300-3318
-
-
Yang, D.S.1
Stavrides, P.2
Saito, M.3
Kumar, A.4
Rodriguez-Navarro, J.A.5
Pawlik, M.6
-
28
-
-
84863613170
-
Central role of mitofusin 2 in autophagosome-lysosome fusion in cardiomyocytes
-
Zhao, T., Huang, X., Han, L., Wang, X., Cheng, H., Zhao, Y., et al. (2012). Central role of mitofusin 2 in autophagosome-lysosome fusion in cardiomyocytes. J Biol Chem 287, 23615-23625.
-
(2012)
J Biol Chem
, vol.287
, pp. 23615-23625
-
-
Zhao, T.1
Huang, X.2
Han, L.3
Wang, X.4
Cheng, H.5
Zhao, Y.6
-
29
-
-
84876408458
-
Activation of lysosomal function in the course of autophagy via mTORC1 suppression and autophagosomelysosome fusion
-
Zhou, J., Tan, S. H., Nicolas, V., Bauvy, C., Yang, N. D., Zhang, J., et al. (2013). Activation of lysosomal function in the course of autophagy via mTORC1 suppression and autophagosomelysosome fusion. Cell Res 23, 508-523.
-
(2013)
Cell Res
, vol.23
, pp. 508-523
-
-
Zhou, J.1
Tan, S.H.2
Nicolas, V.3
Bauvy, C.4
Yang, N.D.5
Zhang, J.6
-
30
-
-
84859949806
-
Diammonium glycyrrhizinate upregulates PGC-1alpha and protects against Abeta1-42-induced neurotoxicity
-
Zhu, X., Chen, C., Ye, D., Guan, D., Ye, L., Jin, J., et al. (2012). Diammonium glycyrrhizinate upregulates PGC-1alpha and protects against Abeta1-42-induced neurotoxicity. PLoS One 7, e35823.
-
(2012)
PLoS One
, vol.7
, pp. e35823
-
-
Zhu, X.1
Chen, C.2
Ye, D.3
Guan, D.4
Ye, L.5
Jin, J.6
|