Age-related loss of hepatic Nrf2 protein homeostasis: Potential role for heightened expression of miR-146a

Free Radical Biology and Medicine

Volumn 89, Issue , 2015, Pages 1184-1191

  Smith, Eric J ^a,b   Shay, Kate P ^a   Thomas, Nicholas O ^a,b   Butler, Judy A ^a   Finlay, Liam F ^a   Hagen, Tory M ^a  

^a OREGON STATE UNIVERSITY   (United States)

^b OREGON STATE UNIVERSITY   (United States)

Author keywords

Aging; Antioxidant response element; MicroRNA; Nrf2; Translation

Indexed keywords

BORTEZOMIB; MESSENGER RNA; MICRORNA 146A; TRANSCRIPTION FACTOR NRF2; MICRORNA; MIRN146 MICRORNA, RAT;

AGE; ANIMAL CELL; ANIMAL EXPERIMENT; ANTIOXIDANT RESPONSIVE ELEMENT; ARTICLE; CONTROLLED STUDY; GENE EXPRESSION; GENE INDUCTION; LIVER CELL; MALE; MICROARRAY ANALYSIS; NONHUMAN; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN HOMEOSTASIS; PROTEIN SYNTHESIS; RAT; AGING; ANIMAL; CELL CULTURE; CYTOLOGY; FISCHER 344 RAT; GENETICS; HOMEOSTASIS; METABOLISM; PHYSIOLOGY; REAL TIME POLYMERASE CHAIN REACTION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION;

AGING; ANIMALS; CELLS, CULTURED; HEPATOCYTES; HOMEOSTASIS; MALE; MICRORNAS; NF-E2-RELATED FACTOR 2; PROTEIN BIOSYNTHESIS; RATS; RATS, INBRED F344; REAL-TIME POLYMERASE CHAIN REACTION; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, MESSENGER;

EID: 84946722394     PISSN: 08915849     EISSN: 18734596     Source Type: Journal    
DOI: 10.1016/j.freeradbiomed.2015.11.003     Document Type: Article

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