Acute exposure to synthetic pyrethroids causes bioconcentration and disruption of the hypothalamus-pituitary-thyroid axis in zebrafish embryos

Science of the Total Environment

Volumn 542, Issue , 2016, Pages 876-885

  Tu, Wenqing ^a,b   Xu, Chao ^b   Lu, Bin ^b   Lin, Chunmian ^b   Wu, Yongming ^a   Liu, Weiping ^c  

^a INSTITUTE OF APPLIED CHEMISTRY   (China)

^b ZHEJIANG UNIVERSITY OF TECHNOLOGY   (China)

^c ZHEJIANG UNIVERSITY   (China)

Author keywords

Bioconcentration; HTP axis; Pyrethroid insecticides; Zebrafish embryos

Indexed keywords

BIOACCUMULATION; BIOCHEMISTRY; BRAIN; GENES; HORMONES; SIGNAL TRANSDUCTION;

BIOCONCENTRATION; HTP AXIS; PYRETHROID INSECTICIDE; SYNTHETIC PYRETHROIDS; THYROID HORMONE RECEPTOR; TRANSCRIPTIONAL REGULATION; ZEBRAFISH DEVELOPMENT; ZEBRAFISH EMBRYOS;

TRANSCRIPTION;

BIFENTHRIN; CYHALOTHRIN; LIOTHYRONINE; THYROID HORMONE RECEPTOR ALPHA; THYROTROPIN; THYROXINE; TRANSCRIPTION FACTOR; TRANSCRIPTION FACTOR NKX2.1; TRANSCRIPTION FACTOR PAX8; UNCLASSIFIED DRUG; ENDOCRINE DISRUPTOR; PYRETHROID; WATER POLLUTANT;

BIOACCUMULATION; BODY CONDITION; CYPRINID; EMBRYO; ENDOCRINE DISRUPTOR; ENDOCRINE SYSTEM; INSECTICIDE; POLLUTION EFFECT; POLLUTION EXPOSURE; PYRETHROID PESTICIDE;

ADULT; ARTICLE; BINDING AFFINITY; BIOACCUMULATION; BODY HEIGHT; BODY WEIGHT; CONTROLLED STUDY; CRH GENE; DIO2 GENE; DOWN REGULATION; EMBRYO; ENVIRONMENTAL EXPOSURE; FEMALE; GENE; GENE EXPRESSION; GENETIC TRANSCRIPTION; HYDROPHOBICITY; HYPOTHALAMUS HYPOPHYSIS THYROID SYSTEM; MALE; NONHUMAN; PAX8 GENE; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN EXPRESSION; SIGNAL TRANSDUCTION; TR ALPHA GENE; TRANSCRIPTION REGULATION; TSH BETA GENE; TTR GENE; UGT1AB GENE; UPREGULATION; ZEBRA FISH; ANIMAL; DRUG EFFECTS; ENDOCRINE SYSTEM; NONMAMMALIAN EMBRYO; TOXICITY; TOXICITY TESTING; WATER POLLUTANT;

DANIO RERIO; MAMMALIA;

ANIMALS; EMBRYO, NONMAMMALIAN; ENDOCRINE DISRUPTORS; ENDOCRINE SYSTEM; PYRETHRINS; TOXICITY TESTS, ACUTE; WATER POLLUTANTS, CHEMICAL; ZEBRAFISH;

EID: 84946595525     PISSN: 00489697     EISSN: 18791026     Source Type: Journal    
DOI: 10.1016/j.scitotenv.2015.10.131     Document Type: Article

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