Exposure of zebrafish embryos/larvae to TDCPP alters concentrations of thyroid hormones and transcriptions of genes involved in the hypothalamic-pituitary-thyroid axis

Aquatic Toxicology

Volumn 126, Issue , 2013, Pages 207-213

  Wang, Qiangwei ^a,b   Liang, Kang ^c   Liu, Jingfu ^c   Yang, Lihua ^a   Guo, Yongyong ^a   Liu, Chunsheng ^d   Zhou, Bingsheng ^a  

^a INSTITUTE OF HYDROBIOLOGY   (China)

^b UNIVERSITY OF CHINESE ACADEMY OF SCIENCES   (China)

^c RESEARCH CENTER FOR ECO ENVIRONMENTAL SCIENCES   (China)

^d NANJING UNIVERSITY   (China)

Author keywords

HPT axis; Organophosphorus flame retardants; TDCPP; Thyroid endocrine disruption

Indexed keywords

FLAME RETARDANT; LIOTHYRONINE; MESSENGER RNA; THYROID HORMONE; THYROXINE; TRIS (1,3 DICHLORO 2 PROPYL)PHOSPHATE; UNCLASSIFIED DRUG;

BIOTA; CONCENTRATION (COMPOSITION); CYPRINID; EMBRYO; ENDOCRINE DISRUPTOR; ENDOCRINE SYSTEM; GENE; HORMONE; LARVA; METABOLISM; PHOSPHATE; RNA; TOXICITY;

ARTICLE; CONTROLLED STUDY; DEVELOPMENTAL TOXICITY; EMBRYO; ENDOCRINE DISEASE; ENZYME LINKED IMMUNOSORBENT ASSAY; GENE EXPRESSION; GENE EXPRESSION PROFILING; GENETIC TRANSCRIPTION; HATCHING; HEART BEAT; HYPOTHALAMUS HYPOPHYSIS THYROID SYSTEM; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; REAL TIME POLYMERASE CHAIN REACTION; SPINE DISEASE; SURVIVAL; THYROID HORMONE SYNTHESIS; UPREGULATION; WEIGHT REDUCTION; ZEBRA FISH;

ANIMALS; EMBRYO, NONMAMMALIAN; GENE EXPRESSION REGULATION, DEVELOPMENTAL; HYPOTHALAMUS; ORGANOPHOSPHORUS COMPOUNDS; PITUITARY GLAND; THYROID GLAND; THYROID HORMONES; WATER POLLUTANTS, CHEMICAL; ZEBRAFISH;

DANIO RERIO;

EID: 84870671110     PISSN: 0166445X     EISSN: 18791514     Source Type: Journal    
DOI: 10.1016/j.aquatox.2012.11.009     Document Type: Article

References (40)

1. Amsterdam A., Nissen R.M., Sun Z., Swindell E.C., Farrington S., Hopkins N. Identification of 315 genes essential for early zebrafish development. Proceedings of the National Academy of Sciences of the United States of America 2004, 101:12792-12797.
2. Andresen J.A., Grundmann A., Bester K. Organophosphorus flame retardants and plasticisers in surface waters. Science of the Total Environment 2004, 332:155-166.
3. Barter R.A., Klaassen C.D. UDP-glucuronosyltransferase inducers reduce thyroid hormone levels in rats by an extrathyroidal mechanism. Toxicology and Applied Pharmacology 1992, 113:36-42.
4. Barter R.A., Klaassen C.D. Reduction of thyroid hormone levels and alteration of thyroid function by four representative UDP-glucuronosyltransferase inducers in rats. Toxicology and Applied Pharmacology 1994, 128:9-17.
5. Cao S., Zeng X., Song H., Li H., Yu Z., Sheng G., Fu J. Levels and distributions of organophosphate flame retardants and plasticizers in sediment from Taihu Lake. China. Environ. Toxicol. Chem. 2012, 31:1478-1484.
6. Chan T., Longabaugh W., Bolouri H., Chen H., Tseng W., Chao C., Jang T., Lin Y., Hung S., Wang H., Yuh C. Developmental gene regulatory network s in the zebrafi sh embryo. BBA - Gene Regulatory Mechanisms 2009, 1789:279-298.
7. Chen Q., Yu L., Yang L., Zhou B. Bioconcentration and metabolism of decabromodiphenyl ether (BDE-209) result in thyroid endocrine disruption in zebrafish larvae. Aquatic Toxicology 2012, 110:141-148.
8. Crump D., Chiu S., Kennedy S.W. Effects of Tris(1,3-dichloro-2-propyl) phosphate and Tris(1-chloropropyl) phosphate on cytotoxicity and mRNA expression in primary cultures of avian hepatocytes and neuronal cells. Toxicological Sciences 2012, 126:140-148.
9. Dishaw L.V., Powers C.M., Ryde I.T., Roberts S.C., Seidler F.J., Slotkin T.A., Stapleton H.M. Is the pentaBDE replacement, Tris(1,3-dichloro-2-propyl) phosphate (TDCPP), a developmental neurotoxicant? Studies in PC12 cells. Toxicology and Applied Pharmacology 2011, 256:281-289.
10. Duarte-Guterman P., Langlois V.S., Pauli B.D., Trudear V.L. Expression and T3 regulation of thyroid hormone- and sex steroid-related genes during Silurana (Xenopus) tropicalis early development. General and Comparative Endocrinology 2010, 166:428-435.
11. Elsalini O.A., Gartzen J., Cramer M., Rohr K.B. Zebrafish hhex, nk2.1a, and pax2.1 regulate thyroid growth and differentiation downstream of Nodal-dependent transcription factors. Developmental Biology 2003, 263:67-80.
12. Green, N., Schlabach, M., Bakke, T., Brevik, E.M., Dye, C., Herzke, D., Huber, S., Plosz, B., Remberger, M., Schøyen, M., Uggerud, H.T., Vogelsang, C., 2008. Screening of Selected Metals and New Organic Contaminants 2007. NIVA Report 5569-2008, SPFO-Report 1014/2008. TA-2367/2008. ISBN:978-82-577-5304-7.
13. Hallgren S., Darnerud P.O. Polybrominated diphenyl ethers (PBDEs), poly-chlorinated biphenyls (PCBs) and chlorinated paraffins (CPs) in rats-testing interactions and mechanisms for thyroid hormone effects. Toxicology 2002, 177:227-243.
14. Ji C., Jin X., He J., Yin Z. Use of TSHβ:EGFP transgenic zebrafish as a rapid in vivo model for assessing thyroid-disrupting chemical. Toxicology and Applied Pharmacology 2012, 262:149-155.
15. Kambe F., Nomura Y., Okamoto T., Seo H. Redox regulation of thyroid-transcription factors, Pax-8 and TTF-1, is involved in their increased DNA-binding activities by thyrotropin in rat thyroid FRTL-5 cells. Molecular Endocrinology 1996, 10:801-812.
16. Kratzsch J., Pulzer F. Thyroid gland development and defects. Best Practice and Research. Clinical Endocrinology and Metabolism 2008, 22:57-75.
17. Lema S.C., Dickey J.T., Schultz I.R., Swanson P. Thyroid hormone regulation of mRNAs encoding thyrotropin β-subunit, glycoprotein α-subunit, and thyroid hormone receptors α and β in brain, pituitary gland, liver, and gonads of an adult teleost, Pimephales promelas. Journal of Endocrinology 2009, 202:43-54.
18. Liu, C., Wang, Q., Liang, K., Liu, J., Zhou, B., Zhang, X., Liu, H., Giesy, J.P., Yu, H. Effects of Tris(1,3-dichloro-2-propyl) phosphate and triphenyl phosphate on receptor-associated mRNA expression in zebrafish embryos/larvae. Aquatic Toxicology, submitted for publication.
19. Liu C., Zhang X., Deng J., Hecker M., Al-Khedhairy A., Giesy J.P., Zhou B. Effects of prochloraz or propylthiouracil on the cross-talk between the HPG, HPA, and HPT axes in zebrafish. Environmental Science and Technology 2011, 45:769-775.
20. Liu X., Ji K., Choi K. Endocrine disruption potentials of organophosphate flame retardants and related mechanisms in H295R and MVLN cell lines and in zebrafish. Aquatic Toxicology 2012, 114:173-181.
21. Meeker J.D., Stapleton H.M. House dust concentrations of organophosphate flame retardants in relation to hormone levels and semen quality parameters. Environmental Health Perspectives 2010, 118:318-323.
22. NRC., 2000. National Research Council. Toxicological risks of selected flame-retardant chemicals. Subcommittee on Flame Retardant Chemicals, National Research Council, National Aademy of Sciences.
23. Orozco A., Valverde R.C. Thyroid hormone deiodination in fish. Thyroid 2005, 15:799-813.
24. Reimers M.J., Flockton A.R., Tanguay R.L. Ethanol- and acetaldehyde-mediated developmental toxicity in zebrafish. Neurotoxicology and Teratology 2004, 26:769-781.
25. Schmutzler C., Gotthardt I., Hofmann P.J., Radovic B., Kovacs G., Stemmler L., Nobis I., Bacinski A., Mentrup B., Ambrugger P., Gruters A., Malendowicz L.K., Christoffel J., Jarry H., Seidlova-Wuttke D., Wuttke W., Kohrle J. Endocrine disruptors and the thyroid gland-a combined in vitro and in vivo analysis of potential new biomarkers. Environmental Health Perspectives 2007, 115(Suppl. 1):77-83.
26. Shi X., Du Y., Lam P.K.S., Wu R.S.S., Zhou B. Developmental toxicity and alteration of gene expression in zebrafish embryos exposed to PFOS. Toxicology and Applied Pharmacology 2008, 230:23-32.
27. Stapleton H.M., Klosterhaus S., Eagle S., Fuh J., Meeker J.D., Blum A., Webster T.F. Detection of organophosphate flame retardants in furniture foam and US house dust. Environmental Science and Technology 2009, 43:7490-7495.
28. Sundkvist A.M., Olofsson U., Haglund P. Organophosphorus flame retardants and plasticizers in marine and fresh water biota and in human milk. Journal of Environmental Monitoring 2010, 12:943-951.
29. Szabo D.T., Richardson V.M., Ross D.G., Diliberto J.J., Kodavanti P.R., Birnbaum L.S. Effects of perinatal PBDE exposure on hepatic phase I, phase II, phase III, and deiodinase 1 gene expression involved in thyroid hormone metabolism in male rat pups. Toxicological Sciences 2009, 107:27-39.
30. Van der Geyten S., Byamungu N., Reyns G.E., Kühn E.R., Darras V.M. Iodothy-ronine deiodinases and the control of plasma and tissue thyroid hormone levels in hyperthyroid tilapia (Oreochromis niloticus). Journal of Endocrinology 2005, 184:467-479.
31. Van der Veen I., de Boer J. Phosphorus flame retardants: properties, production, environmental occurrence, toxicity and analysis. Chemosphere 2012, 88:1119-1153.
32. Visser T.J. Role of sulfation in thyroid hormone metabolism. Chemico-Biological Interactions 1994, 92:293-303.
33. Walpita C.N., der Geyten S.V., Rurangwa E., Darras V.M. The effect of 3,5,3'-triiodothyronine supplementation on zebrafish (Danio rerio) embryonic development and expression of iodothyronine deiodinases and thyroid hormone receptors. General and Comparative Endocrinology 2007, 152:206-214.
34. Wang X., Liu J., Yin Y. Development of an ultra-high-performance liquid chromatography-tandem mass spectrometry method for high throughput determination of organophosphorus flame retardants in environmental water. Journal of Chromatography A 2011, 1218:6705-6711.
35. Wendl T., Lun K., Mione M., Favor J., Brand M., Wilson S.W., Rohr K.B. Pax2.1 is required for the development of thyroid follicles in zebrafish. Development 2002, 129:3751-3760.
36. World Health Organization Flame retardants: Tris(chloropropyl) phosphate and Tris(2-chloroethyl) phosphate. Environmental Health Criteria 209 1998, World Health Organization, Geneva, Switzerland.
37. Yang L., Kemadjou J.R., Zinsmeister C., Bauer M., Legradi J., Müller F., Pankratz M., Jäkel J., Strähle U. Transcriptional profiling reveals barcode-like toxicogenomic responses in the zebrafish embryo. Genome Biology 2007, 8:R227.
38. Yu L., Deng J., Shi X., Liu C., Yu K., Zhou B. Exposure to DE-71 alters thyroid hormone levels and gene transcription in the hypothalamic-pituitary-thyroid axis of zebrafish larvae. Aquatic Toxicology 2010, 97:226-233.
39. Zhou T., Ross D.G., DeVito M.J., Crofton K.M. Effects of short-term in vivo exposure to polybrominated diphenyl ethers on thyroid hormones and hepatic enzyme activities in weanling rats. Toxicological Sciences 2001, 61:76-82.
40. Zoeller R.T., Tan S.W., Tyl R.W. General background on the hypothalamic-pituitary-thyroid (HPT) axis. Critical Reviews in Toxicology 2007, 37:11-53.