-
1
-
-
0021273866
-
Mechanisms governing the relative proportions of thyroxine and 3,5,3′-triiodothyronine in thyroid secretion
-
Lauberg P 1984 Mechanisms governing the relative proportions of thyroxine and 3,5,3′-triiodothyronine in thyroid secretion. Metabolism 33:379-392.
-
(1984)
Metabolism
, vol.33
, pp. 379-392
-
-
Lauberg, P.1
-
2
-
-
0017714686
-
Triiodothyronine, thyroxine, and iodine in purified thyroglobulin from patients with Graves' disease
-
Izumi M, Larsen PR 1977 Triiodothyronine, thyroxine, and iodine in purified thyroglobulin from patients with Graves' disease. J Clin Invest 59:1105-1112.
-
(1977)
J Clin Invest
, vol.59
, pp. 1105-1112
-
-
Izumi, M.1
Larsen, P.R.2
-
3
-
-
0016679179
-
Thyroidal triiodothyronine and thyroxine in Graves' disease: Correlation with presurgical treatment, thyroid status, and iodine content
-
Larsen PR 1975 Thyroidal triiodothyronine and thyroxine in Graves' disease: Correlation with presurgical treatment, thyroid status, and iodine content. J Clin Endocrinol Metab 41:1098-1104.
-
(1975)
J Clin Endocrinol Metab
, vol.41
, pp. 1098-1104
-
-
Larsen, P.R.1
-
4
-
-
0026334925
-
Selenocysteine confers the biochemical properties of the type I iodothyronine deiodinase
-
Berry MJ, Kieffer JD, Harney JW, Larsen PR 1991 Selenocysteine confers the biochemical properties of the type I iodothyronine deiodinase. J Biol Chem 266:14155-14158.
-
(1991)
J Biol Chem
, vol.266
, pp. 14155-14158
-
-
Berry, M.J.1
Kieffer, J.D.2
Harney, J.W.3
Larsen, P.R.4
-
5
-
-
0034522027
-
The role of selenocysteine of 133 in catalysis by the human type 2 iodothyronine deiodinase
-
Buettner C, Harney JW, Larsen PR 2000 The role of selenocysteine of 133 in catalysis by the human type 2 iodothyronine deiodinase. Endocrinology 141:4606-4612.
-
(2000)
Endocrinology
, vol.141
, pp. 4606-4612
-
-
Buettner, C.1
Harney, J.W.2
Larsen, P.R.3
-
6
-
-
0036191639
-
Biochemistry, cellular and molecular biology, and physiological roles of the iodothyronine selenodeiodinases
-
Bianco AC, Salvatore D, Gereben B, Berry MJ, Larsen PR 2002 Biochemistry, cellular and molecular biology, and physiological roles of the iodothyronine selenodeiodinases. Endocr Rev 23:38-89.
-
(2002)
Endocr Rev
, vol.23
, pp. 38-89
-
-
Bianco, A.C.1
Salvatore, D.2
Gereben, B.3
Berry, M.J.4
Larsen, P.R.5
-
7
-
-
0029832961
-
Type 2 iodothyronine deiodinase is highly expressed in human thyroid
-
Salvatore D, Tu H, Harney JW, Larsen PR 1996 Type 2 iodothyronine deiodinase is highly expressed in human thyroid. J Clin Invest 98:962-968.
-
(1996)
J Clin Invest
, vol.98
, pp. 962-968
-
-
Salvatore, D.1
Tu, H.2
Harney, J.W.3
Larsen, P.R.4
-
8
-
-
0025979337
-
Type I iodothyronine deiodinase is a selenocysteine-containing enzyme
-
Berry MJ, Banu L, Larsen PR 1991 Type I iodothyronine deiodinase is a selenocysteine-containing enzyme. Nature 349:438-440
-
(1991)
Nature
, vol.349
, pp. 438-440
-
-
Berry, M.J.1
Banu, L.2
Larsen, P.R.3
-
9
-
-
0031768323
-
Further characterization of thyroid hormone response elements in the human type 1 iodothyronine deiodinase gene
-
Zhang C, Kim S, Harney JW, Larsen PR 1998 Further characterization of thyroid hormone response elements in the human type 1 iodothyronine deiodinase gene. Endocrinology 139:1156-1163.
-
(1998)
Endocrinology
, vol.139
, pp. 1156-1163
-
-
Zhang, C.1
Kim, S.2
Harney, J.W.3
Larsen, P.R.4
-
10
-
-
0025182133
-
Synergistic effect of thyroid hormone and thyrotropin on iodothyronine 5′-deiodinase in FRTL-5 rat thyroid cells
-
Toyoda N, Nisihikawa M., Horimoto M., Yoshikawa N, Mori Y, Yoshimura M., Masaki H, Tanaka K, Inada M 1990 Synergistic effect of thyroid hormone and thyrotropin on iodothyronine 5′-deiodinase in FRTL-5 rat thyroid cells. Endocrinology 127:1199-1205.
-
(1990)
Endocrinology
, vol.127
, pp. 1199-1205
-
-
Toyoda, N.1
Nisihikawa, M.2
Horimoto, M.3
Yoshikawa, N.4
Mori, Y.5
Yoshimura, M.6
Masaki, H.7
Tanaka, K.8
Inada, M.9
-
11
-
-
0037370458
-
Regulation of iodothyronine deiodinases in the Pax-8-/- mouse model of congenital hypothyroidism
-
Friedrichsen S, Christ S, Heuer H, Schafer MK, Mansouri A, Bauer A, Visser TJ 2003 Regulation of iodothyronine deiodinases in the Pax-8-/- mouse model of congenital hypothyroidism. Endocrinology 144:777-784.
-
(2003)
Endocrinology
, vol.144
, pp. 777-784
-
-
Friedrichsen, S.1
Christ, S.2
Heuer, H.3
Schafer, M.K.4
Mansouri, A.5
Bauer, A.6
Visser, T.J.7
-
12
-
-
85047681858
-
Characterization of the 5-flanking and 5′-untranslated regions of the cyclic adenosine 3′,5′-monophosphate-responsive human type 2 iodothyronine deiodinase gene
-
Bartha T, Kim SW, Salvatore D, Gereben B, Tu HM, Harney JW, Rudas P, Larsen PR 2000 Characterization of the 5-flanking and 5′-untranslated regions of the cyclic adenosine 3′,5′-monophosphate-responsive human type 2 iodothyronine deiodinase gene. Endocrinology 141:229-237.
-
(2000)
Endocrinology
, vol.141
, pp. 229-237
-
-
Bartha, T.1
Kim, S.W.2
Salvatore, D.3
Gereben, B.4
Tu, H.M.5
Harney, J.W.6
Rudas, P.7
Larsen, P.R.8
-
13
-
-
0035131051
-
The human, but not rat, dio2 gene is stimulated by thyroid transcription factor-1 (TTF-1)
-
Gereben B, Salvatore D, Harney JW, Tu HM, Larsen PR 2001 The human, but not rat, dio2 gene is stimulated by thyroid transcription factor-1 (TTF-1). Mol. Endocrinol 15:112-124.
-
(2001)
Mol Endocrinol
, vol.15
, pp. 112-124
-
-
Gereben, B.1
Salvatore, D.2
Harney, J.W.3
Tu, H.M.4
Larsen, P.R.5
-
14
-
-
0030691866
-
Thyroid hormones inhibit type 2 iodothyronine deiodinase in the rat cerebral cortex by both pre- and posttranslational mechanisms
-
Burmeister LA, Pachucki J, St. Germain DL 1997 Thyroid hormones inhibit type 2 iodothyronine deiodinase in the rat cerebral cortex by both pre- and posttranslational mechanisms. Endocrinology 138:5231-5237.
-
(1997)
Endocrinology
, vol.138
, pp. 5231-5237
-
-
Burmeister, L.A.1
Pachucki, J.2
St. Germain, D.L.3
-
15
-
-
0023936716
-
The effects and interactions of substrates, inhibitors, and the cellular thiol-disulfide balance on the regulation of type II iodothyronine 5′-deiodinase
-
St. Germain DL 1988 The effects and interactions of substrates, inhibitors, and the cellular thiol-disulfide balance on the regulation of type II iodothyronine 5′-deiodinase. Endocrinology 122:1860-1868.
-
(1988)
Endocrinology
, vol.122
, pp. 1860-1868
-
-
St. Germain, D.L.1
-
16
-
-
0034979464
-
Expression and regulation of type II iodothyronine deiodinase in human thyroid gland
-
Murakami M, Ataki O, Hosoi Y, Kamiya Y, Morimura T, Ogiwara T, Mizuma H, Mori M 2001 Expression and regulation of type II iodothyronine deiodinase in human thyroid gland. Endocrinology 142:2961-2967.
-
(2001)
Endocrinology
, vol.142
, pp. 2961-2967
-
-
Murakami, M.1
Ataki, O.2
Hosoi, Y.3
Kamiya, Y.4
Morimura, T.5
Ogiwara, T.6
Mizuma, H.7
Mori, M.8
-
17
-
-
5444271023
-
Thyroid development and its disorders: Genetics and molecular mechanisms
-
De Felice M, Di Lauro R. 2004 Thyroid development and its disorders: Genetics and molecular mechanisms. Endocr Rev 25:722-746.
-
(2004)
Endocr Rev
, vol.25
, pp. 722-746
-
-
De Felice, M.1
Di Lauro, R.2
-
18
-
-
0036215398
-
The synergistic activity of thyroid transcription factor 1 and Pax 8 relies on the promoter/enhancer interplay
-
Miccadei S, De Leo R, Zammarchi E, Natali PG, Civitareale D 2002 The synergistic activity of thyroid transcription factor 1 and Pax 8 relies on the promoter/enhancer interplay. Mol Endocrinol 16:837-846.
-
(2002)
Mol Endocrinol
, vol.16
, pp. 837-846
-
-
Miccadei, S.1
De Leo, R.2
Zammarchi, E.3
Natali, P.G.4
Civitareale, D.5
-
19
-
-
0032709533
-
Thyroid-specific gene expression in the multi-step process of thyroid carcinogenesis
-
Ros P, Rossi DL, Acebron A, Santisteban P 1999 Thyroid-specific gene expression in the multi-step process of thyroid carcinogenesis. Biochemie 81:389-396.
-
(1999)
Biochemie
, vol.81
, pp. 389-396
-
-
Ros, P.1
Rossi, D.L.2
Acebron, A.3
Santisteban, P.4
-
20
-
-
0028123016
-
Expression of the thyroid-specific transcription factors TTF-1 and Pax-8 in human thyroid neoplasms
-
Fabbro D, Di Loreto C, Beltrami A, Belfiore A, Di Lauro R, Damante G 1994 Expression of the thyroid-specific transcription factors TTF-1 and Pax-8 in human thyroid neoplasms. Cancer Res 54:4744-4749.
-
(1994)
Cancer Res
, vol.54
, pp. 4744-4749
-
-
Fabbro, D.1
Di Loreto, C.2
Beltrami, A.3
Belfiore, A.4
Di Lauro, R.5
Damante, G.6
-
21
-
-
0017184389
-
A rapid and sensitive method for the quantitation of microgram quantities of protein utilising the principle of protein-dye binding
-
Bradford MM 1976 A rapid and sensitive method for the quantitation of microgram quantities of protein utilising the principle of protein-dye binding. Anal Biochem 72:248-254.
-
(1976)
Anal Biochem
, vol.72
, pp. 248-254
-
-
Bradford, M.M.1
-
22
-
-
0018974004
-
Iodothyronine 5′ deiodinase from rat kidney: Substrat specifity and the 5′-deioidnation of reverse triiodothyronine
-
Leonard JL, Resenberg IN. 1980 Iodothyronine 5′ deiodinase from rat kidney: Substrat specifity and the 5′-deioidnation of reverse triiodothyronine. Endocrinology 107:1376-1383.
-
(1980)
Endocrinology
, vol.107
, pp. 1376-1383
-
-
Leonard, J.L.1
Resenberg, I.N.2
-
23
-
-
0023277545
-
Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction
-
Chomczynski P, Sacchi N 1987 Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction. Anal Biochem 162:156-159.
-
(1987)
Anal Biochem
, vol.162
, pp. 156-159
-
-
Chomczynski, P.1
Sacchi, N.2
-
24
-
-
0037906387
-
Pax-8 expression correlates with type II 5′ deiodinase expression in thyroids from patients with Graves' disease
-
Ambroziak M, Pachucki J, Chojnowski K, Wiechno W, Nauman J, Nauman A 2003 Pax-8 expression correlates with type II 5′ deiodinase expression in thyroids from patients with Graves' disease. Thyroid 13:141-148.
-
(2003)
Thyroid
, vol.13
, pp. 141-148
-
-
Ambroziak, M.1
Pachucki, J.2
Chojnowski, K.3
Wiechno, W.4
Nauman, J.5
Nauman, A.6
-
25
-
-
0035036974
-
Type I 5′-iodothyronine deiodinase activity and mRNA are remarkably reduced in renal clear cell carcinoma
-
Pachucki J, Ambroziak M, Tanski Z, Luczak J, Nauman J, Nauman A 2001 Type I 5′-iodothyronine deiodinase activity and mRNA are remarkably reduced in renal clear cell carcinoma. J Endocrinol Invest 24:253-261.
-
(2001)
J Endocrinol Invest
, vol.24
, pp. 253-261
-
-
Pachucki, J.1
Ambroziak, M.2
Tanski, Z.3
Luczak, J.4
Nauman, J.5
Nauman, A.6
-
26
-
-
0037474242
-
The paired domain-containing factor Pax-8 and the homeodomian-containing factor TTF-1 directly interact and synergistically activate transcription
-
Di Palma T, Nitsch R, Mascia A, Nitsch L, Di Lauro R, Zannini M 2003 The paired domain-containing factor Pax-8 and the homeodomian-containing factor TTF-1 directly interact and synergistically activate transcription. J Biol Chem 278:3395-3402.
-
(2003)
J Biol Chem
, vol.278
, pp. 3395-3402
-
-
Di Palma, T.1
Nitsch, R.2
Mascia, A.3
Nitsch, L.4
Di Lauro, R.5
Zannini, M.6
-
27
-
-
0034105756
-
Expression of thyroid transcription factor-1 (TTF-I) in human C cells and medullary thyroid carcinoma
-
Katoh R, Miyagi E, Nakamura N, Li X, Suzuki K, Kakudo K, Kobayashi M, Kawaoi A 2000 Expression of thyroid transcription factor-1 (TTF-I) in human C cells and medullary thyroid carcinoma. Hum Pathol 31:386-393.
-
(2000)
Hum Pathol
, vol.31
, pp. 386-393
-
-
Katoh, R.1
Miyagi, E.2
Nakamura, N.3
Li, X.4
Suzuki, K.5
Kakudo, K.6
Kobayashi, M.7
Kawaoi, A.8
-
28
-
-
0033803375
-
Variable Expression of keratins and nearly uniform lack of thyroid transcription factor 1 in thyroid anaplastic carcinoma
-
Mettinen M, Franssila KO 2000 Variable Expression of keratins and nearly uniform lack of thyroid transcription factor 1 in thyroid anaplastic carcinoma. Hum Pathol 31:1139-1145.
-
(2000)
Hum Pathol
, vol.31
, pp. 1139-1145
-
-
Mettinen, M.1
Franssila, K.O.2
-
29
-
-
0034090430
-
Thyroid transcription factor-1 in normal, hyperplasctic, and neoplastic follicular thyroid cells examined by immunochemistry and nonradioactive in situ hybridization
-
Katoh R, Kawaoi A, Miyagi E, Li X, Suzuki K, Nakamura Y, Kakudo K 2000 Thyroid transcription factor-1 in normal, hyperplasctic, and neoplastic follicular thyroid cells examined by immunochemistry and nonradioactive in situ hybridization. Mod. Pathol. 13:570-576.
-
(2000)
Mod Pathol
, vol.13
, pp. 570-576
-
-
Katoh, R.1
Kawaoi, A.2
Miyagi, E.3
Li, X.4
Suzuki, K.5
Nakamura, Y.6
Kakudo, K.7
-
30
-
-
0030070917
-
Mapping and functional role of phosphorylation sites in the thyroid transcription factor 1 (TTF-1)
-
Zannini M, Acebron A, De Felice M, Arnone MI, Martin-Perez J, Santisteban P 1996 Mapping and functional role of phosphorylation sites in the thyroid transcription factor 1 (TTF-1). J Biol Chem 27:2249-2254.
-
(1996)
J Biol Chem
, vol.27
, pp. 2249-2254
-
-
Zannini, M.1
Acebron, A.2
De Felice, M.3
Arnone, M.I.4
Martin-Perez, J.5
Santisteban, P.6
-
31
-
-
0028998576
-
The DNA binding activity and the dimerization ability of the thyroid tran-scription factor 1 are redox regulated
-
Arnone MI, Zannini M, Di Lauro R 1995 The DNA binding activity and the dimerization ability of the thyroid tran-scription factor 1 are redox regulated. J Biol Chem 270:12048-12055.
-
(1995)
J Biol Chem
, vol.270
, pp. 12048-12055
-
-
Arnone, M.I.1
Zannini, M.2
Di Lauro, R.3
-
32
-
-
0028786558
-
Redundant domains contribute to the transcriptional activity of the thyroid transcription factor 1
-
De Felice M, Damante G, Zannini M, Francis-Lang H, Di Lauro R 1995 Redundant domains contribute to the transcriptional activity of the thyroid transcription factor 1. J Biol Chem 270:26649-26656.
-
(1995)
J Biol Chem
, vol.270
, pp. 26649-26656
-
-
De Felice, M.1
Damante, G.2
Zannini, M.3
Francis-Lang, H.4
Di Lauro, R.5
-
33
-
-
0035328634
-
Transcriptional activation of the thyroglobulin promoter directing sucide gene expression by thyroid transcription factor-1 in thyroid cancer cells
-
Shimura H, Suzuki H, Miyazaki A, Furuya F, Ohta K, Haraguchi K, Endo T, Onaya T 2001 Transcriptional activation of the thyroglobulin promoter directing sucide gene expression by thyroid transcription factor-1 in thyroid cancer cells. Cancer Res 61:3640-3646.
-
(2001)
Cancer Res
, vol.61
, pp. 3640-3646
-
-
Shimura, H.1
Suzuki, H.2
Miyazaki, A.3
Furuya, F.4
Ohta, K.5
Haraguchi, K.6
Endo, T.7
Onaya, T.8
-
34
-
-
0027252649
-
The oncogenic potential of Pax genes
-
Maulbecker CC, Gruss P 1993 The oncogenic potential of Pax genes. EMBO J 12:2361-2367.
-
(1993)
EMBO J
, vol.12
, pp. 2361-2367
-
-
Maulbecker, C.C.1
Gruss, P.2
-
35
-
-
28344455469
-
The expression of the human type I 5′ iodothyronine deiodinase depends on the methylation status of the cell
-
Mentrup B, Herbert S, Schmutzler C, Koehrle J 2002 The expression of the human type I 5′ iodothyronine deiodinase depends on the methylation status of the cell. J Endocrinol Invest 25:29.
-
(2002)
J Endocrinol Invest
, vol.25
, pp. 29
-
-
Mentrup, B.1
Herbert, S.2
Schmutzler, C.3
Koehrle, J.4
-
36
-
-
0036964285
-
Functionally impaired TR mutants are present in thyroid papillary cancer
-
Puzianowska-Kuznicka M, Krystyniak A, Madej A, Cheng SY, Nauman J 2002 Functionally impaired TR mutants are present in thyroid papillary cancer. J Clin Endocrinol Metab 87:1120-1128.
-
(2002)
J Clin Endocrinol Metab
, vol.87
, pp. 1120-1128
-
-
Puzianowska-Kuznicka, M.1
Krystyniak, A.2
Madej, A.3
Cheng, S.Y.4
Nauman, J.5
-
37
-
-
0033666089
-
Screening for genetic aberrations in papillary thyroid cancer by using comparative genomic hybridization
-
Singh B, Lim D, Cigudosa JC, Ghossein R, Shaha AR, Poluri A, Wreesmann VB, Tuttle M, Shah JP, Rao PH 2000 Screening for genetic aberrations in papillary thyroid cancer by using comparative genomic hybridization. Surgery 128:889-893.
-
(2000)
Surgery
, vol.128
, pp. 889-893
-
-
Singh, B.1
Lim, D.2
Cigudosa, J.C.3
Ghossein, R.4
Shaha, A.R.5
Poluri, A.6
Wreesmann, V.B.7
Tuttle, M.8
Shah, J.P.9
Rao, P.H.10
-
38
-
-
0031172520
-
Strucuture of the human type I iodothyronine 5′-deiodinase gene and localization to chromsome Ip32-p33
-
Jakobs TC, Koehler MR, Schmutzler C, Glaser F, Schmid M, Koehrle J 1997 Strucuture of the human type I iodothyronine 5′-deiodinase gene and localization to chromsome Ip32-p33. Genomics 42:361-363.
-
(1997)
Genomics
, vol.42
, pp. 361-363
-
-
Jakobs, T.C.1
Koehler, M.R.2
Schmutzler, C.3
Glaser, F.4
Schmid, M.5
Koehrle, J.6
-
39
-
-
85047684915
-
The mRNA structure has potenet regulatory effects on type 2 iodothyronine deiodinase expression
-
Gereben B, Kollar A, Harney JW, Larsen PR 2002 The mRNA structure has potenet regulatory effects on type 2 iodothyronine deiodinase expression. Mol Endocrinol 16:1667-1679.
-
(2002)
Mol Endocrinol
, vol.16
, pp. 1667-1679
-
-
Gereben, B.1
Kollar, A.2
Harney, J.W.3
Larsen, P.R.4
-
40
-
-
0033650596
-
Selective proteolysis of human type 2 deiodinase: A novel ubiquitin-proteasomal mediated mechanism for regulation of hormone activation
-
Gereben B, Goncalves C, Harney JW, Larsen PR, Bianco AC 2000 Selective proteolysis of human type 2 deiodinase: A novel ubiquitin-proteasomal mediated mechanism for regulation of hormone activation. Mol Endocrinol 14:1697-1708.
-
(2000)
Mol Endocrinol
, vol.14
, pp. 1697-1708
-
-
Gereben, B.1
Goncalves, C.2
Harney, J.W.3
Larsen, P.R.4
Bianco, A.C.5
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