Exposure to DE-71 alters thyroid hormone levels and gene transcription in the hypothalamic-pituitary-thyroid axis of zebrafish larvae

Aquatic Toxicology

Volumn 97, Issue 3, 2010, Pages 226-233

  Yu, Liqin ^a,b   Deng, Jun ^a   Shi, Xiongjie ^a   Liu, Chunsheng ^a   Yu, Ke ^a   Zhou, Bingsheng ^a  

^a INSTITUTE OF HYDROBIOLOGY   (China)

^b UNIVERSITY OF CHINESE ACADEMY OF SCIENCES   (China)

Author keywords

Gene expression; Hypothalamic pituitary thyroid axis; PBDEs; Thyroid hormone; Zebrafish

Indexed keywords

CORTICOTROPIN RELEASING FACTOR; DE 71; GLUCURONOSYLTRANSFERASE; MESSENGER RNA; OXIDOREDUCTASE; POLYBROMINATED DIPHENYL ETHER; PREALBUMIN; PROTEIN SLC5A5; SODIUM IODIDE SYMPORTER; THYROGLOBULIN; THYROID HORMONE; THYROID HORMONE RECEPTOR; THYRONINE DEIODINASE 1; THYRONINE DEIODINASE 2; THYROTROPIN; THYROXINE; TRANSCRIPTION FACTOR; TRANSCRIPTION FACTOR NKX2.1; TRANSCRIPTION FACTOR PAX8; UNCLASSIFIED DRUG; URIDINEDIPHOSPHATE GLUCURONOSYLTRANSFERASE 1AB;

CONCENTRATION (COMPOSITION); DOSE-RESPONSE RELATIONSHIP; EMBRYO; FISH; GENE EXPRESSION; HOMEOSTASIS; HORMONE; LARVA; MITOCHONDRION; PBDE; RNA; TOXICITY TEST;

ARTICLE; CONTROLLED STUDY; EMBRYO; EMBRYO DEVELOPMENT; EXPOSURE; GENETIC TRANSCRIPTION; HOMEOSTASIS; HYPOTHALAMUS HYPOPHYSIS THYROID SYSTEM; LARVA; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; REAL TIME POLYMERASE CHAIN REACTION; RNA ISOLATION; TOXICITY; UPREGULATION; ZEBRA FISH;

ANIMALS; DOSE-RESPONSE RELATIONSHIP, DRUG; FLAME RETARDANTS; HALOGENATED DIPHENYL ETHERS; HYPOTHALAMO-HYPOPHYSEAL SYSTEM; LARVA; RNA, MESSENGER; THYROID GLAND; THYROID HORMONES; TRANSCRIPTION, GENETIC; ZEBRAFISH; ZEBRAFISH PROTEINS;

DANIO RERIO;

EID: 77951939324     PISSN: 0166445X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.aquatox.2009.10.022     Document Type: Article

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