Effects of perfluorooctane sulfonate on RAT thyroid hormone biosynthesis and metabolism

Environmental Toxicology and Chemistry

Volumn 28, Issue 5, 2009, Pages 990-996

  Yu, Wen Guang ^a   Liu, Wei ^a   Jin, Yi He ^a  

^a DALIAN UNIVERSITY OF TECHNOLOGY   (China)

Author keywords

Perfluorooctane sulfonate; Sprague dawley rat; Thyroid hormone Uridine diphosphoglucuronosyl transferases; Type 1 deiodinase

Indexed keywords

DRINKING WATER; GLUCURONIDATION; ISOFORMS; MESSENGER RNAS (MRNA); PERFLUOROOCTANE SULFONATE; PERFLUOROOCTANE SULFONATES; PERSISTENT ORGANIC POLLUTANTS; SODIUM IODIDES; SPRAGUE-DAWLEY RAT; SPRAGUE-DAWLEY RATS; THYROID FUNCTION; THYROID HORMONE URIDINE DIPHOSPHOGLUCURONOSYL TRANSFERASES; THYROID HORMONES; THYROID PEROXIDASE; TOXIC EFFECT; TYPE 1 DEIODINASE;

BIOCHEMICAL ENGINEERING; BIOCHEMISTRY; BIOSYNTHESIS; BODY FLUIDS; HORMONES; LIVER; METABOLISM; NUCLEIC ACIDS; ORGANIC POLLUTANTS; POTABLE WATER; RATS; RNA; SODIUM;

ENZYMES;

DRINKING WATER; GLUCURONOSYLTRANSFERASE 1A1; GLUCURONOSYLTRANSFERASE 1A6; IODIDE PEROXIDASE; LIOTHYRONINE; MESSENGER RNA; PERFLUOROOCTANESULFONIC ACID; SODIUM IODIDE SYMPORTER; THYROID HORMONE; THYROID PEROXIDASE; THYROTROPIN; THYROTROPIN RECEPTOR; THYROXINE; TYPE 1 DEIODINASE; UNCLASSIFIED DRUG;

DRINKING WATER; ENZYME ACTIVITY; HORMONE; METABOLISM; ORGANIC POLLUTANT; POLLUTION EFFECT; RNA; RODENT; SULFONATE; TOXICITY TEST;

ANIMAL EXPERIMENT; ARTICLE; CONTROLLED STUDY; DOSE RESPONSE; ENVIRONMENTAL EXPOSURE; FREE THYROXINE INDEX; GLUCURONIDATION; HORMONE ACTION; LIOTHYRONINE BLOOD LEVEL; LIVER; MALE; NONHUMAN; NUCLEOTIDE SEQUENCE; ORGANIC POLLUTION; POLLUTANT; PRIORITY JOURNAL; RAT; SERUM; THYROID FUNCTION; THYROID GLAND; THYROID HORMONE METABOLISM; THYROID HORMONE SYNTHESIS; THYROTROPIN BLOOD LEVEL; THYROXINE BLOOD LEVEL;

ALKANESULFONIC ACIDS; ANIMALS; BODY WEIGHT; DOSE-RESPONSE RELATIONSHIP, DRUG; ENVIRONMENTAL POLLUTANTS; FLUOROCARBONS; GENE EXPRESSION REGULATION; IODIDE PEROXIDASE; MALE; ORGAN SIZE; RATS; RATS, SPRAGUE-DAWLEY; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, MESSENGER; THYROID GLAND; THYROID HORMONES; THYROXINE;

RATTUS;

EID: 67249099546     PISSN: 07307268     EISSN: None     Source Type: Journal    
DOI: 10.1897/08-345.1     Document Type: Article

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