Accumulation and biotransformation of BDE-47 by zebrafish larvae and teratogenicity and expression of genes along the hypothalamus-pituitary-thyroid axis

Environmental Science and Technology

Volumn 46, Issue 23, 2012, Pages 12943-12951

  Zheng, Xinmei ^a   Zhu, Yuting ^a   Liu, Chunsheng ^a   Liu, Hongling ^a   Giesy, John P ^a,b,c   Hecker, Markus ^d   Lam, Michael H W ^c   Yu, Hongxia ^a  

^a NANJING UNIVERSITY   (China)

^b UNIVERSITY OF SASKATCHEWAN   (Canada)

^c CITY UNIVERSITY OF HONG KONG   (Hong Kong)

^d University of Saskatchewan   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

ADVERSE EFFECT; BROMINATED FLAME RETARDANTS; DANIO RERIO; HORMONE RECEPTORS; NATURAL PRODUCTS; POST-FERTILIZATION; THYROGLOBULIN; THYROID HORMONE RECEPTOR; THYROID HORMONES; THYROTROPIN-RELEASING HORMONES; TOXIC COMPOUNDS; TRANSTHYRETIN; ZEBRAFISH;

BRAIN; ENDOCRINOLOGY; GENES; HORMONES;

TRANSCRIPTION;

2,2',4,4' TETRABROMODIPHENYLETHER; FLAME RETARDANT; MESSENGER RNA; POLYBROMINATED DIPHENYL ETHER; PREALBUMIN; PROTIRELIN; SODIUM IODIDE SYMPORTER; THYROGLOBULIN; THYROID HORMONE RECEPTOR ALPHA; THYROID HORMONE RECEPTOR BETA; THYROTROPIN RECEPTOR; UNCLASSIFIED DRUG;

BIOACCUMULATION; BIOTRANSFORMATION; CYPRINID; EMBRYO; GENE EXPRESSION; HORMONE; LARVA; MITOCHONDRIAL DNA; TOXIC SUBSTANCE; TOXICOLOGY;

ANIMAL EXPERIMENT; ARTICLE; BEHAVIOR; BIOACCUMULATION; BIOTRANSFORMATION; CONCENTRATION (PARAMETERS); CONTROLLED STUDY; DEVELOPMENTAL TOXICITY; DOWN REGULATION; EMBRYO; EMBRYO DEVELOPMENT; EXPOSURE; GENE EXPRESSION; GENE EXPRESSION REGULATION; GENETIC TRANSCRIPTION; HYPOTHALAMUS HYPOPHYSIS THYROID SYSTEM; LARVA; LC 50; LIQUID LIQUID EXTRACTION; MASS FRAGMENTOGRAPHY; METABOLISM; NONHUMAN; ONTOGENY; REAL TIME POLYMERASE CHAIN REACTION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; TERATOGENICITY; UPREGULATION; ZEBRA FISH;

ANIMALS; EMBRYO, NONMAMMALIAN; HYPOTHALAMUS; LARVA; PITUITARY GLAND; POLYBROMINATED BIPHENYLS; THYROID GLAND; TRANSCRIPTOME; WATER POLLUTANTS, CHEMICAL; ZEBRAFISH;

DANIO RERIO;

EID: 84870498484     PISSN: 0013936X     EISSN: 15205851     Source Type: Journal    
DOI: 10.1021/es303289n     Document Type: Article

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