Nanoparticulate carbon black in cigarette smoke induces DNA cleavage and Th17-mediated emphysema

eLife

Volumn 4, Issue OCTOBER2015, 2015, Pages

  You, Ran ^a   Lu, Wen ^a   Shan, Ming ^a   Berlin, Jacob M ^b   Samuel, Errol L G ^c   Marcano, Daniela C ^c   Sun, Zhengzong ^c   Sikkema, William K A ^c   Yuan, Xiaoyi ^a   Song, Lizhen ^a   Hendrix, Amanda Y ^a   Tour, James M ^c   Corry, David B ^a,d   Kheradmand, Farrah ^a,d  

^a BAYLOR COLLEGE OF MEDICINE   (United States)

^b CITY OF HOPE NATIONAL MEDICAL CENTER   (United States)

^c RICE UNIVERSITY   (United States)

^d DEPARTMENT OF VETERANS AFFAIRS   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CARBON BLACK NANOPARTICLE; CIGARETTE SMOKE; GAMMA INTERFERON; INTERLEUKIN 17; NANOPARTICLE; TRANSCRIPTION FACTOR FOXP3; UNCLASSIFIED DRUG; INFLAMMASOME; SMOKE; SOOT;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BONE MARROW DERIVED DENDRITIC CELL; CD4+ T LYMPHOCYTE; CELL DIFFERENTIATION; COMPUTER ASSISTED TOMOGRAPHY; CONTROLLED STUDY; DNA CLEAVAGE; EMPHYSEMA; ENZYME LINKED IMMUNOSORBENT ASSAY; FEMALE; FLOW CYTOMETRY; HISTOPATHOLOGY; IMMUNOHISTOCHEMISTRY; INFRARED SPECTROSCOPY; MASS FRAGMENTOGRAPHY; MOUSE; NONHUMAN; RAMAN SPECTROMETRY; REAL TIME POLYMERASE CHAIN REACTION; SMOKING; TH17 CELL; THERMOGRAVIMETRY; TRANSMISSION ELECTRON MICROSCOPY; WESTERN BLOTTING; X RAY PHOTOELECTRON SPECTROSCOPY; ANIMAL; ANTIGEN PRESENTING CELL; CHEMICALLY INDUCED; DENDRITIC CELL; DRUG EFFECTS; INFLAMMATION; LUNG EMPHYSEMA; METABOLISM; PATHOLOGY; PHAGOCYTE; PHYSIOLOGY; SMOKE; SOOT; TOXICITY;

ANIMALS; ANTIGEN-PRESENTING CELLS; DENDRITIC CELLS; DNA CLEAVAGE; INFLAMMASOMES; INFLAMMATION; MICE; NANOPARTICLES; PHAGOCYTES; PULMONARY EMPHYSEMA; SMOKE; SMOKING; SOOT; TH17 CELLS;

EID: 84946592857     PISSN: None     EISSN: 2050084X     Source Type: Journal    
DOI: 10.7554/eLife.09623     Document Type: Article

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