Increased expression of CD4+IL-17+ cells in the lung tissue of patients with stable chronic obstructive pulmonary disease (COPD) and smokers

International Immunopharmacology

Volumn 15, Issue 1, 2013, Pages 58-66

  Zhang, Jianquan ^a   Chu, Shuyuan ^a   Zhong, Xiaoning ^a   Lao, Qifang ^a   He, Zhiyi ^a   Liang, Yi ^a  

^a FIRST AFFILIATED HOSPITAL OF GUANGXI MEDICAL UNIVERSITY   (China)

Author keywords

CD4+IL 17+ cell; Chronic obstructive pulmonary disease; Lung tissue; Smoker

Indexed keywords

INTERLEUKIN 17; INTERLEUKIN 21; MESSENGER RNA;

ADULT; AIRFLOW; ARTICLE; CD4+ T LYMPHOCYTE; CELL COUNT; CHRONIC OBSTRUCTIVE LUNG DISEASE; CLINICAL ARTICLE; CONTROLLED STUDY; FEMALE; HUMAN; IMMUNOFLUORESCENCE; LUNG ALVEOLUS CELL; LUNG FUNCTION; LUNG PARENCHYMA; MALE; PATHOGENESIS; PRIORITY JOURNAL; PROTEIN EXPRESSION; PULMONARY ARTERY; QUANTITATIVE ANALYSIS; REAL TIME POLYMERASE CHAIN REACTION; SMOKING;

AGED; CD4-POSITIVE T-LYMPHOCYTES; FEMALE; HUMANS; INTERLEUKIN-17; INTERLEUKINS; LUNG; MALE; MIDDLE AGED; PULMONARY DISEASE, CHRONIC OBSTRUCTIVE; SMOKING;

EID: 84872296816     PISSN: 15675769     EISSN: 18781705     Source Type: Journal    
DOI: 10.1016/j.intimp.2012.10.018     Document Type: Article

References (33)

1. A. Di Stefano, G. Caramori, F.L. Ricciardolo, A. Capelli, I.M. Adcock, and C.F. Donner Cellular and molecular mechanisms in chronic obstructive pulmonary disease: an overview Clin Exp Allergy 34 2004 1156 1167
2. P.J. Barnes Chronic obstructive pulmonary disease N Engl J Med 343 2000 269 280
3. W.D. Cornwell, V. Kim, C. Song, and T.J. Rogers Pathogenesis of inflammation and repair in advanced COPD Semin Respir Crit Care Med 31 2010 257 266
4. N. Lane, R.A. Robins, J. Corne, and L. Fairclough Regulation in chronic obstructive pulmonary disease: the role of regulatory T-cells and Th17 cells Clin Sci (Lond) 119 2010 75 86
5. + effector T cells develop via a lineage distinct from the T helper type 1 and 2 lineages Nat Immunol 6 2005 1123 1132
6. A. Kimura, and T. Kishimoto Th17 cells in inflammation Int Immunopharmacol 11 3 2011 319 322
7. L.A. Solt, N. Kumar, P. Nuhant, Y. Wang, J.L. Lauer, and J. Liu Suppression of TH17 differentiation and autoimmunity by a synthetic ROR ligand Nature 472 2011 491 494
8. M. Pelletier, L. Maggi, A. Micheletti, E. Lazzeri, N. Tamassia, and C. Costantini Evidence for a cross-talk between human neutrophils and Th17 cells Blood 115 2010 335 343
9. Y. Chen, P. Thai, Y.H. Zhao, Y.S. Ho, M.M. DeSouza, and R. Wu Stimulation of airway mucin gene expression by interleukin (IL)-17 through IL-6 paracrine/autocrine loop J Biol Chem 278 2003 17,036 17,043
10. E. Bettelli, T. Korn, M. Oukka, and V. Kuchroo Induction and effector functions of Th17 cells Nature 453 2008 1051 1057
11. K.A. Casey, and M.F. Mescher IL-21 promotes differentiation of naive CD8 T cells to a unique effector phenotype J Immunol 178 2007 7640 7648
12. J.S. Yi, J.T. Ingram, and A.J. Zajac IL-21 deficiency influences CD8 T cell quality and recall responses following an acute viral infection J Immunol 185 2010 4835 4845
13. + Th17 type cells associated with chronic cigarette smoke induced airspace enlargement Immunol Lett 121 2008 13 21
14. M.I. Vargas-Rojas, A. Ramírez-Venegas, L. Limón-Camacho, L. Ochoa, R. Hernández-Zenteno, and R.H. Sansores Increase of Th17 cells in peripheral blood of patients with chronic obstructive pulmonary disease Respir Med 105 2011 1648 1654
15. C. Doe, M. Bafadhel, S. Siddiqui, D. Desai, V. Mistry, and P. Rugman Expression of the T helper 17-associated cytokines IL-17A and IL-17F in asthma and COPD Chest 138 2010 1140 1147
16. A. Barczyk, W. Pierzchala, and E. Sozañska Interleukin-17 in sputum correlates with airway hyperresponsiveness to methacholine Respir Med 97 2003 726 733
17. S. Chu, X. Zhong, J. Zhang, Q. Lao, Z. He, and J. Bai The expression of Foxp3 and ROR gamma t in lung tissues from normal smokers and chronic obstructive pulmonary disease patients Int Immunopharmacol 11 2011 1780 1788
18. J.Q. Zhang, Q.F. Lao, S.Y. Chu, J. Bai, and X.N. Zhong Interleukin-17 expression and significance in normal lung function smokers and chronic obstructive pulmonary disease patients Zhonghua Yi Xue Za Zhi 90 2010 1431 1435
19. A. Eustace, L.J. Smyth, L. Mitchell, K. Williamson, J. Plumb, and D. Singh Identification of cells expressing IL-17A and IL-17F in the lungs of patients with COPD Chest 139 2011 1089 1100
20. P.J. Barnes, J.M. Drazen, S.I. Rennard, and N.C. Thomson Asthma and COPD: basic mechanisms and clinical management printed resource 2002 Academic Press London 34
21. K.F. Rabe, S. Hurd, A. Anzueto, P.J. Barnes, S.A. Buist, and P. Calverley Global initiative for chronic obstructive lung disease: global strategy for the diagnosis, management, and prevention of chronic obstructive pulmonary disease: GOLD executive summary Am J Respir Crit Care Med 176 2007 532 555
22. http://www.nccn.org
23. M. Cosio, H. Ghezzo, J.C. Hogg, R. Corbin, M. Loveland, and J. Dosman The relations between structural changes in small airways and pulmonary-function tests N Engl J Med 298 1978 1277 1281
24. +ve cells in the lungs of smokers with chronic obstructive pulmonary disease Am J Respir Crit Care Med 160 1999 711 717
25. K.J. Livak, and T.D. Schmittgen Analysis of relative gene expression data using real-time quantitative PCR and the 2(- Delta Delta C (T)) method Methods 25 2001 402 408
26. J.K. Kolls, and A. Lindén Interleukin-17 family members and inflammation Immunity 21 2004 467 476
27. R. Nurieva, X.O. Yang, G. Martinez, Y. Zhang, A.D. Panopoulos, and L. Ma Essential autocrine regulation by IL-21 in the generation of inflammatory T cells Nature 448 2007 480 483
28. R.R. Barbosa, S.P. Silva, S.L. Silva, A.C. Melo, E. Pedro, and M.P. Barbosa Primary B-cell deficiencies reveal a link between human IL-17-producing CD4 T-cell homeostasis and B-cell differentiation PLoS One 6 2011 e22848
29. M.C. Duan, X.N. Zhong, Y. Huang, Z.Y. He, and H.J. Tang Mechanisms and dynamics of Th17 cells in mice with cigarette smoke-induced emphysema Zhonghua Yi Xue Za Zhi 91 2011 1996 2000
30. + T helper lymphocytes on cigarette smoke-induced lung inflammation and emphysema in mice Zhonghua Jie He He Hu Xi Za Zhi 34 2011 259 264
31. + T cell Zhonghua Yi Xue Za Zhi 92 16 2012 1129 1132
32. C. Pridgeon, L. Bugeon, L. Donnelly, U. Straschil, S.J. Tudhope, and P. Fenwick Regulation of IL-17 in chronic inflammation in the human lung Clin Sci (Lond) 120 12 2011 515 524
33. P.J. Barnes Similarities and differences in inflammatory mechanisms of asthma and COPD Breathe 7 3 2011 229 238