메뉴 건너뛰기




Volumn 8, Issue 3, 2012, Pages 285-292

Autoimmunity in chronic obstructive pulmonary disease: Clinical and experimental evidence

Author keywords

adaptive immunity; antigen presenting cells; cytokines; Th1; Th17

Indexed keywords

ALPHA 1 ANTITRYPSIN; GAMMA INTERFERON; INTERLEUKIN 13; INTERLEUKIN 17; INTERLEUKIN 4; LEUKOCYTE ELASTASE; MACROPHAGE ELASTASE; MATRIX METALLOPROTEINASE; TUMOR NECROSIS FACTOR;

EID: 84858433903     PISSN: 1744666X     EISSN: 17448409     Source Type: Journal    
DOI: 10.1586/eci.12.7     Document Type: Review
Times cited : (77)

References (63)
  • 1
    • 84889745031 scopus 로고    scopus 로고
    • WH Giles. Deaths from chronic obstructive pulmonary disease - United States, 2000- 2005
    • Brown DW, Croft JB, Greenlund KJ, WH Giles. Deaths from chronic obstructive pulmonary disease - United States, 2000-2005. J. Am. Med. Assoc. 301(13), 1331-1333 (2009).
    • (2009) J. Am. Med. Assoc. , vol.301 , Issue.13 , pp. 1331-1333
    • Brown, D.W.1    Croft, J.B.2    Greenlund, K.J.3
  • 2
    • 0037114131 scopus 로고    scopus 로고
    • Alpha1-antitrypsin determines the pattern of emphysema and function in tobacco smoke-exposed mice: Parallels with human disease
    • Takubo Y, Guerassimov A, Ghezzo H et al. Alpha1-antitrypsin determines the pattern of emphysema and function in tobacco smoke-exposed mice: Parallels with human disease. Am. J. Respir. Crit. Care Med. 166(12 Pt 1), 1596-1603 (2002).
    • (2002) Am. J. Respir. Crit. Care Med. , vol.166 , Issue.12 PART 1 , pp. 1596-1603
    • Takubo, Y.1    Guerassimov, A.2    Ghezzo, H.3
  • 4
    • 16244415510 scopus 로고    scopus 로고
    • Early smoking-induced lung lesions in asymptomatic subjects. Correlations between high resolution dynamic CT and pulmonary function testing
    • Spaggiari E, Zompatori M, Verduri A et al. Early smoking-induced lung lesions in asymptomatic subjects. Correlations between high resolution dynamic CT and pulmonary function testing. Radiol. Med. 109(1-2), 27-39 (2005).
    • (2005) Radiol. Med. , vol.109 , Issue.1-2 , pp. 27-39
    • Spaggiari, E.1    Zompatori, M.2    Verduri, A.3
  • 5
    • 79957914848 scopus 로고    scopus 로고
    • Cross-sectional analysis of the utility of pulmonary function tests in predicting emphysema in ever-smokers
    • Hesselbacher SE, Ross R, Schabath MB et al. Cross-sectional analysis of the utility of pulmonary function tests in predicting emphysema in ever-smokers. Int. J. Environ. Res. Public Health 8(5), 1324-1340 (2011).
    • (2011) Int. J. Environ. Res. Public Health , vol.8 , Issue.5 , pp. 1324-1340
    • Hesselbacher, S.E.1    Ross, R.2    Schabath, M.B.3
  • 6
    • 34249670253 scopus 로고    scopus 로고
    • A risk model for prediction of lung cancer
    • Spitz MR, Hong WK, Amos CI et al. A risk model for prediction of lung cancer. J. Natl Cancer Inst. 99(9), 715-726 (2007).
    • (2007) J. Natl Cancer Inst. , vol.99 , Issue.9 , pp. 715-726
    • Spitz, M.R.1    Hong, W.K.2    Amos, C.I.3
  • 7
    • 52749088978 scopus 로고    scopus 로고
    • Association of radiographic emphysema and airflow obstruction with lung cancer
    • Wilson DO, Weissfeld JL, Balkan A et al. Association of radiographic emphysema and airflow obstruction with lung cancer. Am. J. Respir. Crit. Care Med. 178(7), 738-744 (2008).
    • (2008) Am. J. Respir. Crit. Care Med. , vol.178 , Issue.7 , pp. 738-744
    • Wilson, D.O.1    Weissfeld, J.L.2    Balkan, A.3
  • 8
    • 67650709487 scopus 로고    scopus 로고
    • Recent advances in the genetics of autoimmune disease
    • Gregersen PK, Olsson LM. Recent advances in the genetics of autoimmune disease. Annu. Rev. Immunol. 27, 363-391 (2009).
    • (2009) Annu. Rev. Immunol. , vol.27 , pp. 363-391
    • Gregersen, P.K.1    Olsson, L.M.2
  • 9
    • 4344572315 scopus 로고
    • The serum alpha-l-antitrypsin in families with hypo-alpha-l- antitrypsinemia
    • Laurell CB, Eriksson S. The serum alpha-l-antitrypsin in families with hypo-alpha-l-antitrypsinemia. Clin. Chim. Acta. 11, 395-398 (1965).
    • (1965) Clin. Chim. Acta. , vol.11 , pp. 395-398
    • Laurell, C.B.1    Eriksson, S.2
  • 10
    • 77949911882 scopus 로고    scopus 로고
    • The COPD genetic association compendium: A comprehensive online database of COPD genetic associations
    • Castaldi PJ, Cho MH, Cohn M et al. The COPD genetic association compendium: A comprehensive online database of COPD genetic associations. Hum. Mol. Genet. 19(3), 526-534 (2010).
    • (2010) Hum. Mol. Genet. , vol.19 , Issue.3 , pp. 526-534
    • Castaldi, P.J.1    Cho, M.H.2    Cohn, M.3
  • 11
    • 79959756889 scopus 로고    scopus 로고
    • The role of proteases, endoplasmic reticulum stress and SERPINA1 heterozygosity in lung disease and alpha-1 anti-trypsin deficiency
    • Greene CM, Hassan T, Molloy K, McElvaney NG. The role of proteases, endoplasmic reticulum stress and SERPINA1 heterozygosity in lung disease and alpha-1 anti-trypsin deficiency. Expert Rev. Respir. Med. 5(3), 395-411 (2011).
    • (2011) Expert Rev. Respir. Med. , vol.5 , Issue.3 , pp. 395-411
    • Greene, C.M.1    Hassan, T.2    Molloy, K.3    McElvaney, N.G.4
  • 12
    • 78650797925 scopus 로고    scopus 로고
    • Genome-wide association study identifies BICD1 as a susceptibility gene for emphysema
    • Kong X, Cho MH, Anderson W et al. Genome-wide association study identifies BICD1 as a susceptibility gene for emphysema. Am. J. Respir. Crit. Care Med. 183(1), 43-49 (2011).
    • (2011) Am. J. Respir. Crit. Care Med. , vol.183 , Issue.1 , pp. 43-49
    • Kong, X.1    Cho, M.H.2    Anderson, W.3
  • 14
    • 63449101907 scopus 로고    scopus 로고
    • A genome-wide association study in chronic obstructive pulmonary disease (COPD): Identification of two major susceptibility loci
    • Pillai SG, Ge D, Zhu G et al. A genome-wide association study in chronic obstructive pulmonary disease (COPD): Identification of two major susceptibility loci. PLoS Genet. 5(3), e1000421 (2009).
    • (2009) PLoS Genet. , vol.5 , Issue.3
    • Pillai, S.G.1    Ge, D.2    Zhu, G.3
  • 15
    • 41649103052 scopus 로고    scopus 로고
    • A variant associated with nicotine dependence, lung cancer and peripheral arterial disease
    • Thorgeirsson TE, Geller F, Sulem P et al. A variant associated with nicotine dependence, lung cancer and peripheral arterial disease. Nature 452(7187), 638-642 (2008).
    • (2008) Nature , vol.452 , Issue.7187 , pp. 638-642
    • Thorgeirsson, T.E.1    Geller, F.2    Sulem, P.3
  • 16
    • 77951748276 scopus 로고    scopus 로고
    • Sequence variants at CHRNB3-CHRNA6 and CYP2A6 affect smoking behavior
    • Thorgeirsson TE, Gudbjartsson DF, Surakka I et al. Sequence variants at CHRNB3-CHRNA6 and CYP2A6 affect smoking behavior. Nat. Genet. 42(5), 448-453 (2010).
    • (2010) Nat. Genet. , vol.42 , Issue.5 , pp. 448-453
    • Thorgeirsson, T.E.1    Gudbjartsson, D.F.2    Surakka, I.3
  • 17
    • 0015903352 scopus 로고
    • The induction of emphysema with elastase. I. the evolution of the lesion and the influence of serum
    • Kaplan PD, Kuhn C, Pierce JA. The induction of emphysema with elastase. I. The evolution of the lesion and the influence of serum. J. Lab. Clin. Med. 82(3), 349-356 (1973).
    • (1973) J. Lab. Clin. Med. , vol.82 , Issue.3 , pp. 349-356
    • Kaplan, P.D.1    Kuhn, C.2    Pierce, J.A.3
  • 18
    • 0027971976 scopus 로고
    • Elastolytic metalloproteinases produced by human mononuclear phagocytes. Potential roles in destructive lung disease
    • Shapiro SD. Elastolytic metalloproteinases produced by human mononuclear phagocytes. Potential roles in destructive lung disease. Am. J. Respir. Crit. Care Med. 150(6 Pt 2), S160-S164 (1994).
    • (1994) Am. J. Respir. Crit. Care Med. , vol.150 , Issue.6 PART 2
    • Shapiro, S.D.1
  • 19
    • 0024360852 scopus 로고
    • Elastin degradation by human alveolar macrophages. A prominent role of metalloproteinase activity
    • Senior RM, Connolly NL, Cury JD, Welgus HG, Campbell EJ. Elastin degradation by human alveolar macrophages. A prominent role of metalloproteinase activity. Am. Rev. Respir. Dis. 139(5), 1251-1256 (1989).
    • (1989) Am. Rev. Respir. Dis. , vol.139 , Issue.5 , pp. 1251-1256
    • Senior, R.M.1    Connolly, N.L.2    Cury, J.D.3    Welgus, H.G.4    Campbell, E.J.5
  • 20
    • 66149093072 scopus 로고    scopus 로고
    • The pathology of chronic obstructive pulmonary disease
    • Hogg JC, Timens W. The pathology of chronic obstructive pulmonary disease. Annu. Rev. Pathol. 4, 435-459 (2009).
    • (2009) Annu. Rev. Pathol. , vol.4 , pp. 435-459
    • Hogg, J.C.1    Timens, W.2
  • 21
    • 0036727064 scopus 로고    scopus 로고
    • Acute cigarette smoke-induced connective tissue breakdown requires both neutrophils and macrophage metalloelastase in mice
    • Churg A, Zay K, Shay S et al. Acute cigarette smoke-induced connective tissue breakdown requires both neutrophils and macrophage metalloelastase in mice. Am. J. Respir. Cell Mol. Biol. 27(3), 368-374 (2002).
    • (2002) Am. J. Respir. Cell Mol. Biol. , vol.27 , Issue.3 , pp. 368-374
    • Churg, A.1    Zay, K.2    Shay, S.3
  • 22
    • 34249652351 scopus 로고    scopus 로고
    • Antielastin autoimmunity in tobacco smoking-induced emphysema
    • Lee SH, Goswami S, Grudo A et al. Antielastin autoimmunity in tobacco smoking-induced emphysema. Nat. Med. 13(5), 567-569 (2007).
    • (2007) Nat. Med. , vol.13 , Issue.5 , pp. 567-569
    • Lee, S.H.1    Goswami, S.2    Grudo, A.3
  • 23
    • 66649127821 scopus 로고    scopus 로고
    • Immunologic aspects of chronic obstructive pulmonary disease
    • Cosio MG, Saetta M, Agusti A. Immunologic aspects of chronic obstructive pulmonary disease. N. Engl. J. Med. 360(23), 2445-2454 (2009).
    • (2009) N. Engl. J. Med. , vol.360 , Issue.23 , pp. 2445-2454
    • Cosio, M.G.1    Saetta, M.2    Agusti, A.3
  • 24
    • 0021170197 scopus 로고
    • Val-Gly-Val- Ala -Pro-Gly, a repeating peptide in elastin, is chemotactic for fibroblasts and monocytes
    • Senior RM, Griffin GL, Mecham RP et al. Val-Gly-Val-Ala-Pro-Gly, a repeating peptide in elastin, is chemotactic for fibroblasts and monocytes. J. Cell Biol. 99(3), 870-874 (1984).
    • (1984) J. Cell Biol. , vol.99 , Issue.3 , pp. 870-874
    • Senior, R.M.1    Griffin, G.L.2    Mecham, R.P.3
  • 25
    • 51349165795 scopus 로고    scopus 로고
    • Induction of lung emphysema is prevented by l-arginine-threonine-arginine
    • van Houwelingen AH, Weathington NM, Verweij V et al. Induction of lung emphysema is prevented by l-arginine-threonine-arginine. FASEB Journal. 22(9), 3403-3408 (2008).
    • (2008) FASEB Journal. , vol.22 , Issue.9 , pp. 3403-3408
    • Van Houwelingen, A.H.1    Weathington, N.M.2    Verweij, V.3
  • 26
    • 33644828187 scopus 로고    scopus 로고
    • A novel peptide CXCR ligand derived from extracellular matrix degradation during airway inflammation
    • Weathington NM, van Houwelingen AH, Noerager BD et al. A novel peptide CXCR ligand derived from extracellular matrix degradation during airway inflammation. Nat. Med. 12(3), 317-323 (2006).
    • (2006) Nat. Med. , vol.12 , Issue.3 , pp. 317-323
    • Weathington, N.M.1    Van Houwelingen, A.H.2    Noerager, B.D.3
  • 27
    • 0032798485 scopus 로고    scopus 로고
    • CD8+ve cells in the lungs of smokers with chronic obstructive pulmonary disease
    • Saetta M, Baraldo S, Corbino L et al. CD8+ve cells in the lungs of smokers with chronic obstructive pulmonary disease. Am. J. Respir. Crit. Care Med. 160(2), 711-717 (1999).
    • (1999) Am. J. Respir. Crit. Care Med. , vol.160 , Issue.2 , pp. 711-717
    • Saetta, M.1    Baraldo, S.2    Corbino, L.3
  • 28
    • 0036724894 scopus 로고    scopus 로고
    • Smoking and lung function of lung health study participants after 11 years
    • Anthonisen NR, Connett JE, Murray RP. Smoking and lung function of lung health study participants after 11 years. Am. J. Respir. Crit. Care Med. 166(5), 675-679 (2002).
    • (2002) Am. J. Respir. Crit. Care Med. , vol.166 , Issue.5 , pp. 675-679
    • Anthonisen, N.R.1    Connett, J.E.2    Murray, R.P.3
  • 29
    • 0032719586 scopus 로고    scopus 로고
    • Chronic obstructive pulmonary disease. Inflammation of small airways and lung parenchyma
    • Cosio MG, Guerassimov A. Chronic obstructive pulmonary disease. Inflammation of small airways and lung parenchyma. Am. J. Respir. Crit. Care Med. 160(5 Pt 2), S21-S25 (1999).
    • (1999) Am. J. Respir. Crit. Care Med. , vol.160 , Issue.5 PART 2
    • Cosio, M.G.1    Guerassimov, A.2
  • 33
    • 84856068597 scopus 로고    scopus 로고
    • Cigarette smoke induction of osteopontin (SPP1) mediates Th17 inflammation in human and experimental emphysema
    • Shan M, Yuan X, Song L et al. Cigarette smoke induction of osteopontin (SPP1) mediates Th17 inflammation in human and experimental emphysema. Sci. Transl. Med. (4), 117 (2012).
    • Sci. Transl. Med. , vol.4 , Issue.117 , pp. 2012
    • Shan, M.1    Yuan, X.2    Song, L.3
  • 34
    • 0031759492 scopus 로고    scopus 로고
    • Advances in the management of Crohn's disease: Economic and clinical potential of infliximab
    • Hanauer SB, Cohen RD, Becker RV 3rd, Larson LR, Vreeland MG. Advances in the management of Crohn's disease: Economic and clinical potential of infliximab. Clin. Ther. 20(5), 1009-1028 (1998).
    • (1998) Clin. Ther. , vol.20 , Issue.5 , pp. 1009-1028
    • Hanauer, S.B.1    Cohen, R.D.2    Larson, L.R.3    Vreeland, M.G.4
  • 35
    • 33644977112 scopus 로고    scopus 로고
    • Cigarette smoke-induced pulmonary emphysema in SCID-mice. Is the acquired immune system required
    • D'Hulst AI, Maes T, Bracke KR et al. Cigarette smoke-induced pulmonary emphysema in SCID-mice. Is the acquired immune system required? Respiratory Research. 6, 147 (2005).
    • (2005) Respiratory Research. , vol.6 , pp. 147
    • D'Hulst, A.I.1    Maes, T.2    Bracke, K.R.3
  • 36
    • 7044229899 scopus 로고    scopus 로고
    • The development of emphysema in cigarette smoke-exposed mice is strain dependent
    • Guerassimov A, Hoshino Y, Takubo Y et al. The development of emphysema in cigarette smoke-exposed mice is strain dependent. Am. J. Respir. Crit. Care Med. 170(9), 974-980 (2004).
    • (2004) Am. J. Respir. Crit. Care Med. , vol.170 , Issue.9 , pp. 974-980
    • Guerassimov, A.1    Hoshino, Y.2    Takubo, Y.3
  • 37
    • 15744363493 scopus 로고    scopus 로고
    • An immune basis for lung parenchymal destruction in chronic obstructive pulmonary disease and emphysema
    • Grumelli S, Corry DB, Song LZ et al. An immune basis for lung parenchymal destruction in chronic obstructive pulmonary disease and emphysema. PLoS Med. 1(1), e8 (2004).
    • (2004) PLoS Med. , vol.1 , Issue.1
    • Grumelli, S.1    Corry, D.B.2    Song, L.Z.3
  • 38
    • 0034988909 scopus 로고    scopus 로고
    • The C-C chemokine receptors CCR4 and CCR8 identify airway T cells of allergen-challenged atopic asthmatics
    • Panina-Bordignon P, Papi A, Mariani M et al. The C-C chemokine receptors CCR4 and CCR8 identify airway T cells of allergen-challenged atopic asthmatics. J. Clin. Invest. 107(11), 1357-1364 (2001).
    • (2001) J. Clin. Invest. , vol.107 , Issue.11 , pp. 1357-1364
    • Panina-Bordignon, P.1    Papi, A.2    Mariani, M.3
  • 41
    • 38349070654 scopus 로고    scopus 로고
    • Autoantibodies in patients with chronic obstructive pulmonary disease
    • Feghali-Bostwick C, Gadgil A, Otterbein L et al. Autoantibodies in patients with chronic obstructive pulmonary disease. Am. J. Respir. Crit. Care Med. 177(2),156-163 (2008).
    • (2008) Am. J. Respir. Crit. Care Med. , vol.177 , Issue.2 , pp. 156-163
    • Feghali-Bostwick, C.1    Gadgil, A.2    Otterbein, L.3
  • 42
    • 79954618688 scopus 로고    scopus 로고
    • Anti-tissue antibodies are related to lung function in chronic obstructive pulmonary disease
    • Nunez B, Sauleda J, Anto JM et al. Anti-tissue antibodies are related to lung function in chronic obstructive pulmonary disease. Am. J. Respir. Crit. Care Med. 1183(8), 1025-1031 (2011).
    • (2011) Am. J. Respir. Crit. Care Med. , vol.1183 , Issue.8 , pp. 1025-1031
    • Nunez, B.1    Sauleda, J.2    Anto, J.M.3
  • 43
    • 73849127430 scopus 로고    scopus 로고
    • Anti-proline-glycine-proline or antielastin autoantibodies are not evident in chronic inflammatory lung disease
    • Greene CM, Low TB, O'Neill SJ, McElvaney NG. Anti-proline-glycine-proline or antielastin autoantibodies are not evident in chronic inflammatory lung disease. Am. J. Respir. Crit. Care Med. 181(1), 31-35 (2009).
    • (2009) Am. J. Respir. Crit. Care Med. , vol.181 , Issue.1 , pp. 31-35
    • Greene, C.M.1    Low, T.B.2    O'Neill, S.J.3    McElvaney, N.G.4
  • 44
    • 58849124841 scopus 로고    scopus 로고
    • Anti-elastin autoantibodies are not present in combined pulmonary fibrosis and emphysema
    • Cottin V, Fabien N, Khouatra C, Moreira A, Cordier JF. Anti-elastin autoantibodies are not present in combined pulmonary fibrosis and emphysema. Eur. Respir. J. 33(1), 219-221 (2009).
    • (2009) Eur. Respir. J. , vol.33 , Issue.1 , pp. 219-221
    • Cottin, V.1    Fabien, N.2    Khouatra, C.3    Moreira, A.4    Cordier, J.F.5
  • 45
    • 0032124204 scopus 로고    scopus 로고
    • Self-reactive antibodies (natural autoantibodies) in healthy individuals
    • Lacroix-Desmazes S, Kaveri SV, Mouthon L et al. Self-reactive antibodies (natural autoantibodies) in healthy individuals. J. Immunol. Methods 216(1-2), 117-137 (1998).
    • (1998) J. Immunol. Methods , vol.216 , Issue.1-2 , pp. 117-137
    • Lacroix-Desmazes, S.1    Kaveri, S.V.2    Mouthon, L.3
  • 47
    • 69949182843 scopus 로고    scopus 로고
    • Autoantibodies and other serological markers in rheumatoid arthritis: Predictors of disease activity
    • da Mota LM, dos Santos Neto LL, de Carvalho JF. Autoantibodies and other serological markers in rheumatoid arthritis: Predictors of disease activity? Clin. Rheumatol. 28(10), 1127-1134 (2009).
    • (2009) Clin. Rheumatol. , vol.28 , Issue.10 , pp. 1127-1134
    • Da Mota, L.M.1    Dos Santos Neto, L.L.2    De Carvalho, J.F.3
  • 48
    • 75749122606 scopus 로고    scopus 로고
    • Autoantibody-dependent and autoantibody-independent roles for B cells in systemic lupus erythematosus: Past, present, and future
    • Jacob N, Stohl W. Autoantibody-dependent and autoantibody-independent roles for B cells in systemic lupus erythematosus: Past, present, and future. Autoimmunity 43(1), 84-97 (2010).
    • (2010) Autoimmunity , vol.43 , Issue.1 , pp. 84-97
    • Jacob, N.1    Stohl, W.2
  • 49
    • 54349108686 scopus 로고    scopus 로고
    • Division of labor between dendritic cell subsets of the lung
    • GeurtsvanKessel CH, Lambrecht BN. Division of labor between dendritic cell subsets of the lung. Mucosal Immunol. 1(6), 442-450 (2008).
    • (2008) Mucosal Immunol. , vol.1 , Issue.6 , pp. 442-450
    • Geurtsvankessel, C.H.1    Lambrecht, B.N.2
  • 50
    • 0034735552 scopus 로고    scopus 로고
    • The dendritic cell receptor for endocytosis, DEC-205, can recycle and enhance antigen presentation via major histocompatibility complex class II-positive lysosomal compartments
    • Mahnke K, Guo M, Lee S et al. The dendritic cell receptor for endocytosis, DEC-205, can recycle and enhance antigen presentation via major histocompatibility complex class II-positive lysosomal compartments. J. Cell Biol. 151(3), 673-684 (2000).
    • (2000) J. Cell Biol. , vol.151 , Issue.3 , pp. 673-684
    • Mahnke, K.1    Guo, M.2    Lee, S.3
  • 51
    • 79251500661 scopus 로고    scopus 로고
    • Phenotypical and functional specialization of FOXP3+ regulatory T cells
    • Campbell DJ, Koch MA. Phenotypical and functional specialization of FOXP3+ regulatory T cells. Nat. Rev. Immunol. 11(2), 119-130 (2011).
    • (2011) Nat. Rev. Immunol. , vol.11 , Issue.2 , pp. 119-130
    • Campbell, D.J.1    Koch, M.A.2
  • 52
    • 34548773945 scopus 로고    scopus 로고
    • Immunohistochemical detection of dendritic cells in human lung tissue
    • Tsoumakidou M, Zhu J, Wang Z et al. Immunohistochemical detection of dendritic cells in human lung tissue. Histopathology 51(4), 565-568 (2007).
    • (2007) Histopathology , vol.51 , Issue.4 , pp. 565-568
    • Tsoumakidou, M.1    Zhu, J.2    Wang, Z.3
  • 53
    • 34248371233 scopus 로고    scopus 로고
    • Accumulation of dendritic cells and increased CCL20 levels in the airways of patients with chronic obstructive pulmonary disease
    • Demedts IK, Bracke KR, Van Pottelberge G et al. Accumulation of dendritic cells and increased CCL20 levels in the airways of patients with chronic obstructive pulmonary disease. Am. J. Respir. Crit. Care Med. 175(10), 998-1005 (2007).
    • (2007) Am. J. Respir. Crit. Care Med. , vol.175 , Issue.10 , pp. 998-1005
    • Demedts, I.K.1    Bracke, K.R.2    Van Pottelberge, G.3
  • 54
    • 77952745967 scopus 로고    scopus 로고
    • Human Rhinovirus proteinase 2A induces Th1 and Th2 immunity in COPD
    • Singh M, Lee S-H, Porter P et al. Human Rhinovirus proteinase 2A induces Th1 and Th2 immunity in COPD. J. Allergy Clin. Immunol. 125, 1369-1378 (2010).
    • (2010) J. Allergy Clin. Immunol. , vol.125 , pp. 1369-1378
    • Singh, M.1    Lee, S.-H.2    Porter, P.3
  • 55
    • 0037722851 scopus 로고    scopus 로고
    • Infectious exacerbations of chronic obstructive pulmonary disease associated with respiratory viruses and non-typeable Haemophilus influenzae
    • Bandi V, Jakubowycz M, Kinyon C et al. Infectious exacerbations of chronic obstructive pulmonary disease associated with respiratory viruses and non-typeable Haemophilus influenzae. FEMS Immunol. Med. Microbiol. 37(1), 69-75 (2003).
    • (2003) FEMS Immunol. Med. Microbiol. , vol.37 , Issue.1 , pp. 69-75
    • Bandi, V.1    Jakubowycz, M.2    Kinyon, C.3
  • 56
    • 0035509117 scopus 로고    scopus 로고
    • Respiratory viruses, symptoms, and inflammatory markers in acute exacerbations and stable chronic obstructive pulmonary disease
    • Seemungal T, Harper-Owen R, Bhowmik A et al. Respiratory viruses, symptoms, and inflammatory markers in acute exacerbations and stable chronic obstructive pulmonary disease. Am. J. Respir. Crit. Care Med. 164(9), 1618-1623 (2001).
    • (2001) Am. J. Respir. Crit. Care Med. , vol.164 , Issue.9 , pp. 1618-1623
    • Seemungal, T.1    Harper-Owen, R.2    Bhowmik, A.3
  • 58
    • 33646375956 scopus 로고    scopus 로고
    • Respiratory syncytial virus, airway inflammation, and FEV1 decline in patients with chronic obstructive pulmonary disease
    • Wilkinson TMA, Donaldson GC, Johnston SL, Openshaw PJM, Wedzicha JA. Respiratory syncytial virus, airway inflammation, and FEV1 decline in patients with chronic obstructive pulmonary disease. Am. J. Respir. Crit. Care Med. 173(8), 871-876 (2006).
    • (2006) Am. J. Respir. Crit. Care Med. , vol.173 , Issue.8 , pp. 871-876
    • Wilkinson, T.A.1    Donaldson, G.C.2    Johnston, S.L.3    Openshaw, P.M.4    Wedzicha, J.A.5
  • 59
    • 0033213590 scopus 로고    scopus 로고
    • Differential roles of TLR2 and TLR4 in recognition of Gram-negative and Gram-positive bacterial cell wall components
    • Takeuchi O, Hoshino K, Kawai T et al. Differential roles of TLR2 and TLR4 in recognition of Gram-negative and Gram-positive bacterial cell wall components. Immunity 11(4), 443-451 (1999).
    • (1999) Immunity , vol.11 , Issue.4 , pp. 443-451
    • Takeuchi, O.1    Hoshino, K.2    Kawai, T.3
  • 60
    • 40449118020 scopus 로고    scopus 로고
    • Cigarette smoke-induced pulmonary inflammation is TLR4/MyD88 and IL-1R1/MyD88 signaling dependent
    • Doz E, Noulin N, Boichot E et al. Cigarette smoke-induced pulmonary inflammation is TLR4/MyD88 and IL-1R1/MyD88 signaling dependent. J. Immunol. 180(2), 1169-1178 (2008).
    • (2008) J. Immunol. , vol.180 , Issue.2 , pp. 1169-1178
    • Doz, E.1    Noulin, N.2    Boichot, E.3
  • 61
    • 78751692199 scopus 로고    scopus 로고
    • The T-helper cell type 1 immune response to Gram-negative bacterial infections is impaired in COPD
    • Knobloch J, Schild K, Jungck D et al. The T-helper cell type 1 immune response to Gram-negative bacterial infections is impaired in COPD. Am. J. Respir. Crit. Care Med. 183(2), 204-214 (2011).
    • (2011) Am. J. Respir. Crit. Care Med. , vol.183 , Issue.2 , pp. 204-214
    • Knobloch, J.1    Schild, K.2    Jungck, D.3
  • 63
    • 0035423344 scopus 로고    scopus 로고
    • End-stage chronic obstructive pulmonary disease: The cigarette is burned out but inflammation rages on
    • Shapiro SD. End-stage chronic obstructive pulmonary disease: The cigarette is burned out but inflammation rages on. Am. J. Respir. Crit. Care Med. 164(3), 339-340 (2001).
    • (2001) Am. J. Respir. Crit. Care Med. , vol.164 , Issue.3 , pp. 339-340
    • Shapiro, S.D.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.