Prokineticin 2 facilitates mechanical allodynia induced by α,β-methylene ATP in rats

European Journal of Pharmacology

Volumn 767, Issue , 2015, Pages 24-29

  Ren, Cuixia ^a   Qiu, Chun Yu ^a   Gan, Xiong ^a   Liu, Ting Ting ^a   Qu, Zu Wei ^a   Rao, Zhiguo ^b   Hu, Wang Ping ^a  

^a HUBEI UNIVERSITY OF SCIENCE AND TECHNOLOGY   (China)

^b General Hospital of Wuhan Military   (China)

Author keywords

Dorsal root ganglion neuron; Electrophysiology; Mechanical allodynia; Prokineticin 2; , Methylene ATP

Indexed keywords

2 [1 (3 DIMETHYLAMINOPROPYL) 3 INDOLYL] 3 (3 INDOLYL)MALEIMIDE; CHEMOKINE; PROKINETICIN 2; PURINERGIC P2X RECEPTOR; PURINERGIC P2X RECEPTOR ANTAGONIST; UNCLASSIFIED DRUG; 2',3'-O-(2,4,6-TRINITRO-CYCLOHEXADIENYLIDINE)ADENOSINE 5'-TRIPHOSPHATE; ADENOSINE TRIPHOSPHATE; ALPHA,BETA-METHYLENEADENOSINE 5'-TRIPHOSPHATE; BISINDOLYLMALEIMIDE I; G PROTEIN COUPLED RECEPTOR; GASTROINTESTINAL HORMONE; INDOLE DERIVATIVE; MALEIMIDE DERIVATIVE; NEUROPEPTIDE; PROK2 PROTEIN, RAT; PROKINETICIN RECEPTOR 2, RAT; PROTEIN KINASE C; PURINERGIC P2X3 RECEPTOR; RECEPTOR;

ALLODYNIA; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONCENTRATION (PARAMETERS); CONTROLLED STUDY; FACILITATION; INTRACELLULAR SIGNALING; MALE; MECHANICAL STIMULATION; NEUROPROTECTION; NONHUMAN; PHARMACOLOGICAL BLOCKING; PRIORITY JOURNAL; RAT; SPINAL GANGLION; ANALOGS AND DERIVATIVES; ANIMAL; ANTAGONISTS AND INHIBITORS; CHEMICALLY INDUCED; DRUG EFFECTS; DRUG POTENTIATION; HYPERALGESIA; MEMBRANE POTENTIAL; PATHOPHYSIOLOGY; PHYSIOLOGY;

ADENOSINE TRIPHOSPHATE; ANIMALS; DRUG SYNERGISM; GANGLIA, SPINAL; GASTROINTESTINAL HORMONES; HYPERALGESIA; INDOLES; MALE; MALEIMIDES; MEMBRANE POTENTIALS; NEUROPEPTIDES; PROTEIN KINASE C; PURINERGIC P2X RECEPTOR ANTAGONISTS; RATS; RECEPTORS, G-PROTEIN-COUPLED; RECEPTORS, PEPTIDE; RECEPTORS, PURINERGIC P2X3;

EID: 84946558436     PISSN: 00142999     EISSN: 18790712     Source Type: Journal    
DOI: 10.1016/j.ejphar.2015.09.047     Document Type: Article

References (32)

1. T.P. Barr, A. Hrnjic, A. Khodorova, J.M. Sprague, and G.R. Strichartz Sensitization of cutaneous neuronal purinergic receptors contributes to endothelin-1-induced mechanical hypersensitivity Pain 155 2014 1091 1101
2. C.C. Chen, A.N. Akopian, L. Sivilotti, D. Colquhoun, G. Burnstock, and J.N. Wood A P2X purinoceptor expressed by a subset of sensory neurons Nature 377 1995 428 431
3. Y. Chen, G.W. Li, C. Wang, Y. Gu, and L.Y. Huang Mechanisms underlying enhanced P2X receptor-mediated responses in the neuropathic pain state Pain 119 2005 38 48
4. M.Y. Cheng, A.G. Lee, C. Culbertson, G. Sun, R.K. Talati, N.C. Manley, X. Li, H. Zhao, D.M. Lyons, Q.Y. Zhou, G.K. Steinberg, and R.M. Sapolsky Prokineticin 2 is an endangering mediator of cerebral ischemic injury Proc. Natl. Acad. Sci. USA 109 2012 5475 5480
5. M.C. de Oliveira Fusaro, A. Pelegrini-da-Silva, D. Araldi, C.A. Parada, and C.H. Tambeli P2X3 and P2X2/3 receptors mediate mechanical hyperalgesia induced by bradykinin, but not by pro-inflammatory cytokines, PGE(2) or dopamine Eur. J. Pharmacol. 649 2010 177 182
6. E. Giannini, R. Lattanzi, A. Nicotra, A.F. Campese, P. Grazioli, I. Screpanti, G. Balboni, S. Salvadori, P. Sacerdote, and L. Negri The chemokine Bv8/prokineticin 2 is up-regulated in inflammatory granulocytes and modulates inflammatory pain Proc. Natl. Acad. Sci. USA 106 2009 14646 14651
7. H.Z. Hu, and Z.W. Li Substance P potentiates ATP-activated currents in rat primary sensory neurons Brain Res. 739 1996 163 168
8. W.P. Hu, C. Zhang, J.D. Li, Z.D. Luo, S. Amadesi, N. Bunnett, and Q.Y. Zhou Impaired pain sensation in mice lacking prokineticin 2 Mol. Pain 2 2006 35
9. M.F. Jarvis, C.T. Wismer, E. Schweitzer, H. Yu, T. van Biesen, K.J. Lynch, E.C. Burgard, and E.A. Kowaluk Modulation of BzATP and formalin induced nociception: attenuation by the P2X receptor antagonist, TNP-ATP and enhancement by the P2X(3) allosteric modulator, cibacron blue Br. J. Pharmacol. 132 2001 259 269
10. R. Lattanzi, D. Maftei, V. Marconi, F. Florenzano, S. Franchi, E. Borsani, L.F. Rodella, G. Balboni, S. Salvadori, P. Sacerdote, and L. Negri Prokineticin 2 upregulation in the peripheral nervous system has a major role in triggering and maintaining neuropathic pain in the chronic constriction injury model BioMed Res. Int. 2015 2015 301292
11. C. Lewis, S. Neidhart, C. Holy, R.A. North, G. Buell, and A. Surprenant Coexpression of P2X2 and P2X3 receptor subunits can account for ATP-gated currents in sensory neurons Nature 377 1995 432 435
12. D.C. Lin, C.M. Bullock, F.J. Ehlert, J.L. Chen, H. Tian, and Q.Y. Zhou Identification and molecular characterization of two closely related G protein-coupled receptors activated by prokineticins/endocrine gland vascular endothelial growth factor J. Biol. Chem. 277 2002 19276 19280
13. D. Maftei, V. Marconi, F. Florenzano, L.A. Giancotti, M. Castelli, S. Moretti, E. Borsani, L.F. Rodella, G. Balboni, L. Luongo, S. Maione, P. Sacerdote, L. Negri, and R. Lattanzi Controlling the activation of the Bv8/prokineticin system reduces neuroinflammation and abolishes thermal and tactile hyperalgesia in neuropathic animals Br. J. Pharmacol. 171 2014 4850 4865
14. S. McGaraughty, C.T. Wismer, C.Z. Zhu, J. Mikusa, P. Honore, K.L. Chu, C.H. Lee, C.R. Faltynek, and M.F. Jarvis Effects of A-317491, a novel and selective P2X3/P2X2/3 receptor antagonist, on neuropathic, inflammatory and chemogenic nociception following intrathecal and intraplantar administration Br. J. Pharmacol. 140 2003 1381 1388
15. L. Negri, and R. Lattanzi Bv8-prokineticins and their receptors: modulators of pain Curr. Pharm. Biotechnol. 12 2011 1720 1727
16. L. Negri, R. Lattanzi, E. Giannini, M. Canestrelli, A. Nicotra, and P. Melchiorri Bv8/Prokineticins and their Receptors A new pronociceptive system Int. Rev. Neurobiol. 85 2009 145 157
17. L. Negri, R. Lattanzi, E. Giannini, M. Colucci, F. Margheriti, P. Melchiorri, V. Vellani, H. Tian, M. De Felice, and F. Porreca Impaired nociception and inflammatory pain sensation in mice lacking the prokineticin receptor PKR1: focus on interaction between PKR1 and the capsaicin receptor TRPV1 in pain behavior J. Neurosci.: Off. J. Soc. Neurosci. 26 2006 6716 6727
18. L. Negri, R. Lattanzi, E. Giannini, A. Metere, M. Colucci, D. Barra, G. Kreil, and P. Melchiorri Nociceptive sensitization by the secretory protein Bv8 Br. J. Pharmacol. 137 2002 1147 1154
19. E.S. Ngan, and P.K. Tam Prokineticin-signaling pathway Int. J. Biochem. Cell Biol. 40 2008 1679 1684
20. M.C. Oliveira, A. Pelegrini-da-Silva, C.H. Tambeli, and C.A. Parada Peripheral mechanisms underlying the essential role of P2X3,2/3 receptors in the development of inflammatory hyperalgesia Pain 141 2009 127 134
21. M. Paukert, R. Osteroth, H.S. Geisler, U. Brandle, E. Glowatzki, J.P. Ruppersberg, and S. Grunder Inflammatory mediators potentiate ATP-gated channels through the P2X(3) subunit J. Biol. Chem. 276 2001 21077 21082
22. F.C. Prado, D. Araldi, A.S. Vieira, M.C. Oliveira-Fusaro, C.H. Tambeli, and C.A. Parada Neuronal P2X3 receptor activation is essential to the hyperalgesia induced by prostaglandins and sympathomimetic amines released during inflammation Neuropharmacology 67 2013 252 258
23. C.Y. Qiu, Y.Q. Liu, F. Qiu, J. Wu, Q.Y. Zhou, and W.P. Hu Prokineticin 2 potentiates acid-sensing ion channel activity in rat dorsal root ganglion neurons J. Neuroinflamm. 9 2012 108
24. F. Qiu, C.Y. Qiu, H. Cai, T.T. Liu, Z.W. Qu, Z. Yang, J.D. Li, Q.Y. Zhou, and W.P. Hu Oxytocin inhibits the activity of acid-sensing ion channels through the vasopressin, V1A receptor in primary sensory neurons Br. J. Pharmacol. 171 2014 3065 3076
25. G.A. Rongen, J.S. Floras, J.W. Lenders, T. Thien, and P. Smits Cardiovascular pharmacology of purines Clin. Sci. 92 1997 13 24
26. H.S. Seo, D.H. Roh, S.G. Kwon, S.Y. Yoon, S.Y. Kang, J.Y. Moon, S.R. Choi, A.J. Beitz, and J.H. Lee Acidic pH facilitates peripheral alphabetameATP-mediated nociception in rats: differential roles of P2X, P2Y, ASIC and TRPV1 receptors in ATP-induced mechanical allodynia and thermal hyperalgesia Neuropharmacology 60 2011 580 586
27. D. Toullec, P. Pianetti, H. Coste, P. Bellevergue, T. Grand-Perret, M. Ajakane, V. Baudet, P. Boissin, E. Boursier, F. Loriolle, and et al. The bisindolylmaleimide GF 109203X is a potent and selective inhibitor of protein kinase C J. Biol. Chem. 266 1991 15771 15781
28. M. Tsuda, S. Koizumi, A. Kita, Y. Shigemoto, S. Ueno, and K. Inoue Mechanical allodynia caused by intraplantar injection of P2X receptor agonist in rats: involvement of heteromeric P2X2/3 receptor signaling in capsaicin-insensitive primary afferent neurons J. Neurosci.: Off. J. Soc. Neurosci. 20 2000 RC90
29. V. Vellani, M. Colucci, R. Lattanzi, E. Giannini, L. Negri, P. Melchiorri, and P.A. McNaughton Sensitization of transient receptor potential vanilloid 1 by the prokineticin receptor agonist Bv8 J. Neurosci.: Off. J. Soc. Neurosci. 26 2006 5109 5116
30. G. Wu, G.T. Whiteside, G. Lee, S. Nolan, M. Niosi, M.S. Pearson, and V.I. Ilyin A-317491, a selective P2X3/P2X2/3 receptor antagonist, reverses inflammatory mechanical hyperalgesia through action at peripheral receptors in rats Eur. J. Pharmacol. 504 2004 45 53
31. Y.C. Xiong, X.M. Li, X.J. Wang, Y.Q. Liu, F. Qiu, D. Wu, Y.B. Gan, B.H. Wang, and W.P. Hu Prokineticin 2 suppresses GABA-activated current in rat primary sensory neurons Neuropharmacology 59 2010 589 594
32. G.Y. Xu, and L.Y. Huang Peripheral inflammation sensitizes P2X receptor-mediated responses in rat dorsal root ganglion neurons J. Neurosci.: Off. J. Soc. Neurosci. 22 2002 93 102