P2X3 and P2X2/3 receptors mediate mechanical hyperalgesia induced by bradykinin, but not by pro-inflammatory cytokines, PGE2 or dopamine

European Journal of Pharmacology

Volumn 649, Issue 1-3, 2010, Pages 177-182

  de Oliveira Fusaro, Maria Cláudia Gonçalves ^a   Pelegrini da Silva, Adriana ^a   Araldi, Dionéia ^a   Parada, Carlos Amílcar ^a   Tambeli, Cláudia Herrera ^a  

^a UNIVERSITY OF CAMPINAS   (Brazil)

Author keywords

ATP; Cytokine; Hyperalgesia; Inflammation; Neutrophil; P2X3 receptor

Indexed keywords

5 [[(3 PHENOXYBENZYL)(1,2,3,4 TETRAHYDRO 1 NAPHTHYL)AMINO]CARBONYL]TRIMELLITIC ACID; ADENOSINE TRIPHOSPHATE; BRADYKININ; CARRAGEENAN; CHEMOATTRACTANT; CHEMOKINE INDUCED CHEMOATTRACTANT 1; DOPAMINE; INTERLEUKIN 1BETA; INTERLEUKIN 6; MYELOPEROXIDASE; PROSTAGLANDIN E2; PURINERGIC P2X2 RECEPTOR; PURINERGIC P2X3 RECEPTOR; PURINERGIC RECEPTOR BLOCKING AGENT; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CONCENTRATION RESPONSE; CONTROLLED STUDY; CYTOKINE RELEASE; ENZYME ACTIVATION; ENZYME ACTIVITY; HYPERALGESIA; LEUKOCYTE MIGRATION; MALE; NEUTROPHIL; NONHUMAN; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN EXPRESSION; PROTEIN FUNCTION; RAT;

ADENOSINE TRIPHOSPHATE; ANIMALS; BRADYKININ; CELL MOVEMENT; CYTOKINES; DINOPROSTONE; DOPAMINE; HYPERALGESIA; INFLAMMATION; INFLAMMATION MEDIATORS; MALE; NERVE TISSUE PROTEINS; NEURONS; NEUTROPHILS; PAIN MEASUREMENT; PURINERGIC P2X RECEPTOR ANTAGONISTS; RATS; RATS, WISTAR; RECEPTORS, PURINERGIC P2X2; RECEPTORS, PURINERGIC P2X3; SUBCUTANEOUS TISSUE; SYNAPTIC TRANSMISSION;

EID: 78049284352     PISSN: 00142999     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ejphar.2010.09.037     Document Type: Article

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