Controlling the activation of the Bv8/prokineticin system reduces neuroinflammation and abolishes thermal and tactile hyperalgesia in neuropathic animals

British Journal of Pharmacology

Volumn 171, Issue 21, 2014, Pages 4850-4865

  Maftei, D ^a   Marconi, V ^a   Florenzano, F ^b   Giancotti, L A ^a   Castelli, M ^c   Moretti, S ^c   Borsani, E ^d   Rodella, L F ^d   Balboni, G ^e   Luongo, L ^f   Maione, S ^f   Sacerdote, P ^c   Negri, L ^a   Lattanzi, R ^a  

^a SAPIENZA UNIVERSITY OF ROME   (Italy)

^b EUROPEAN BRAIN RESEARCH INSTITUTE   (Italy)

^c UNIVERSITY OF MILAN   (Italy)

^d UNIVERSITY OF BRESCIA   (Italy)

^e UNIVERSITY OF CAGLIARI   (Italy)

^f SECOND UNIVERSITY OF NAPLES   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

CHEMOKINE; INTERLEUKIN 10; INTERLEUKIN 1BETA; PROKINETICIN 2; PROKINETICIN RECEPTOR 1; PROKINETICIN RECEPTOR 2; PROKINETICIN RECEPTOR ANTAGONIST; PROTEIN INHIBITOR; UNCLASSIFIED DRUG; G PROTEIN COUPLED RECEPTOR; GASTROINTESTINAL HORMONE; IL10 PROTEIN, MOUSE; IL1B PROTEIN, MOUSE; MESSENGER RNA; NEUROPEPTIDE; PKR1 PROTEIN, MOUSE; PKR2 PROTEIN, MOUSE; PROK2 PROTEIN, MOUSE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; ASTROCYTE; CELL ACTIVATION; CONTROLLED STUDY; ENZYME ACTIVATION; GLIOSIS; HYPERALGESIA; MALE; MOUSE; NERVE COMPRESSION; NERVOUS SYSTEM INFLAMMATION; NEUROPATHIC PAIN; NOCICEPTION; NONHUMAN; PHARMACOLOGICAL BLOCKING; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN LOCALIZATION; SCHWANN CELL; SCIATIC NERVE; THERMAL HYPERALGESIA; TREATMENT DURATION; UPREGULATION; ANIMAL; ANTAGONISTS AND INHIBITORS; GENETICS; GLIA; METABOLISM; NEURALGIA; SPINAL CORD; SPINAL GANGLION;

ANIMALS; GANGLIA, SPINAL; GASTROINTESTINAL HORMONES; HYPERALGESIA; INTERLEUKIN-10; INTERLEUKIN-1BETA; MALE; MICE; NEURALGIA; NEUROGLIA; NEUROPEPTIDES; RECEPTORS, G-PROTEIN-COUPLED; RNA, MESSENGER; SCIATIC NERVE; SPINAL CORD;

EID: 84915792618     PISSN: 00071188     EISSN: 14765381     Source Type: Journal    
DOI: 10.1111/bph.12793     Document Type: Article

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