Oxytocin inhibits the activity of acid-sensing ion channels through the vasopressin, V1A receptor in primary sensory neurons

British Journal of Pharmacology

Volumn 171, Issue 12, 2014, Pages 3065-3076

  Qiu, Fang ^a,b   Qiu, Chun Yu ^a   Cai, Huilan ^a   Liu, Ting Ting ^a   Qu, Zu Wei ^a   Yang, Zhifan ^b   Li, Jia Da ^a,c   Zhou, Qun Yong ^c   Hu, Wang Ping ^a  

^a HUBEI UNIVERSITY OF SCIENCE AND TECHNOLOGY   (China)

^b HUBEI UNIVERSITY   (China)

^c UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

acid sensing ion channel; dorsal root ganglion neuron; electrophysiology; oxytocin; pain; proton gated current; vasopressin

Indexed keywords

1 [[[2 [2 AMINO 4 (METHYLSULFONYL)BUTYRAMIDO] 7,7 DIMETHYLBICYCLO[2.2.1]HEPTAN 1 YL]METHYL]SULFONYL] 4 (2 METHYLPHENYL)PIPERAZINE; ACETIC ACID; ACID SENSING ION CHANNEL; ARGIPRESSIN; OXYTOCIN; OXYTOCIN RECEPTOR; RECEPTOR BLOCKING AGENT; RELCOVAPTAN; UNCLASSIFIED DRUG; VASOPRESSIN; VASOPRESSIN V1A RECEPTOR; ACID SENSING ION CHANNEL BLOCKING AGENT; ANALGESIC AGENT; V1A VASOPRESSIN RECEPTOR, RAT; VASOPRESSIN RECEPTOR;

ACTION POTENTIAL; ANALGESIC ACTIVITY; ANIMAL CELL; ARTICLE; CONTROLLED STUDY; DOSE RESPONSE; DRUG MECHANISM; ELECTROPHYSIOLOGY; FEMALE; ION CURRENT; KNOCKOUT MOUSE; MEMBRANE DEPOLARIZATION; MOUSE; NERVE CELL MEMBRANE STEADY POTENTIAL; NOCICEPTION; NONHUMAN; PAIN; PRIORITY JOURNAL; PROTEIN FUNCTION; RAT; SENSORY NERVE CELL; SPINAL GANGLION; WILD TYPE; ANIMAL; C57BL MOUSE; CHEMICALLY INDUCED; DISEASE MODEL; DRUG EFFECTS; GENETICS; METABOLISM; NOCICEPTIVE PAIN; PSYCHOLOGY; SPRAGUE DAWLEY RAT;

ACETIC ACID; ACID SENSING ION CHANNEL BLOCKERS; ACID SENSING ION CHANNELS; ACTION POTENTIALS; ANALGESICS; ANIMALS; DISEASE MODELS, ANIMAL; DOSE-RESPONSE RELATIONSHIP, DRUG; FEMALE; GANGLIA, SPINAL; MICE, INBRED C57BL; MICE, KNOCKOUT; NOCICEPTION; NOCICEPTIVE PAIN; OXYTOCIN; RATS, SPRAGUE-DAWLEY; RECEPTORS, VASOPRESSIN; SENSORY RECEPTOR CELLS;

EID: 84901402351     PISSN: 00071188     EISSN: 14765381     Source Type: Journal    
DOI: 10.1111/bph.12635     Document Type: Article

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