메뉴 건너뛰기




Volumn 6, Issue SEP, 2015, Pages

Transcriptional enhancers in the regulation of T cell differentiation

Author keywords

Differentiation; Epigenetics; T cell differentiation; Transcription factors; Transcriptional enhancers

Indexed keywords

CD8ALPHA ANTIGEN; TRANSCRIPTION FACTOR;

EID: 84946557892     PISSN: None     EISSN: 16643224     Source Type: Journal    
DOI: 10.3389/fimmu.2015.00462     Document Type: Review
Times cited : (16)

References (82)
  • 1
    • 77952313777 scopus 로고    scopus 로고
    • Differentiation of effector CD4 T cell populations (*)
    • Zhu J, Yamane H, Paul WE. Differentiation of effector CD4 T cell populations (*). Annu Rev Immunol (2010) 28:445-89. doi:10.1146/annurev-immunol-030409-101212.
    • (2010) Annu Rev Immunol , vol.28 , pp. 445-489
    • Zhu, J.1    Yamane, H.2    Paul, W.E.3
  • 2
    • 84911201387 scopus 로고    scopus 로고
    • Molecular regulation of effector and memory T cell differentiation
    • Chang JT, Wherry EJ, Goldrath AW. Molecular regulation of effector and memory T cell differentiation. Nat Immunol (2014) 15(12):1104-15. doi:10.1038/ni.3031.
    • (2014) Nat Immunol , vol.15 , Issue.12 , pp. 1104-1115
    • Chang, J.T.1    Wherry, E.J.2    Goldrath, A.W.3
  • 3
    • 0032981090 scopus 로고    scopus 로고
    • Functional differences between memory and naive CD8 T cells
    • Cho BK, Wang CY, Sugawa S, Eisen HN, Chen JZ. Functional differences between memory and naive CD8 T cells. Proc Natl Acad Sci U S A (1999) 96(6):2976-81. doi:10.1073/Pnas.96.6.2976.
    • (1999) Proc Natl Acad Sci U S A , vol.96 , Issue.6 , pp. 2976-2981
    • Cho, B.K.1    Wang, C.Y.2    Sugawa, S.3    Eisen, H.N.4    Chen, J.Z.5
  • 4
    • 0034231222 scopus 로고    scopus 로고
    • Response of naive and memory CD8+ T cells to antigen stimulation in vivo
    • Veiga-Fernandes H, Walter U, Bourgeois C, McLean A, Rocha B. Response of naive and memory CD8+ T cells to antigen stimulation in vivo. Nat Immunol (2000) 1(1):47-53. doi:10.1038/76907.
    • (2000) Nat Immunol , vol.1 , Issue.1 , pp. 47-53
    • Veiga-Fernandes, H.1    Walter, U.2    Bourgeois, C.3    McLean, A.4    Rocha, B.5
  • 5
    • 0037074012 scopus 로고    scopus 로고
    • Molecular and functional profiling of memory CD8 T cell differentiation
    • Kaech SM, Hemby S, Kersh E, Ahmed R. Molecular and functional profiling of memory CD8 T cell differentiation. Cell (2002) 111(6):837-51. doi:10.1016/S0092-8674(02)01139-X.
    • (2002) Cell , vol.111 , Issue.6 , pp. 837-851
    • Kaech, S.M.1    Hemby, S.2    Kersh, E.3    Ahmed, R.4
  • 6
    • 84912096136 scopus 로고    scopus 로고
    • Distinct epigenetic signatures delineate transcriptional programs during virus-specific CD8(+) T cell differentiation
    • Russ BE, Olshanksy M, Smallwood HS, Li J, Denton AE, Prier JE, et al. Distinct epigenetic signatures delineate transcriptional programs during virus-specific CD8(+) T cell differentiation. Immunity (2014) 41(5):853-65. doi:10.1016/j.immuni.2014.11.001.
    • (2014) Immunity , vol.41 , Issue.5 , pp. 853-865
    • Russ, B.E.1    Olshanksy, M.2    Smallwood, H.S.3    Li, J.4    Denton, A.E.5    Prier, J.E.6
  • 7
    • 0019811465 scopus 로고
    • Expression of a beta-globin gene is enhanced by remote SV40 DNA sequences
    • Banerji J, Rusconi S, Schaffner W. Expression of a beta-globin gene is enhanced by remote SV40 DNA sequences. Cell (1981) 27(2 Pt 1):299-308. doi:10.1016/0092-8674(81)90413-X.
    • (1981) Cell , vol.27 , Issue.2 , pp. 299-308
    • Banerji, J.1    Rusconi, S.2    Schaffner, W.3
  • 8
    • 33847076849 scopus 로고    scopus 로고
    • Chromatin modifications and their function
    • Kouzarides T. Chromatin modifications and their function. Cell (2007) 128(4):693-705. doi:10.1016/J. Cell.2007.02.005.
    • (2007) Cell , vol.128 , Issue.4 , pp. 693-705
    • Kouzarides, T.1
  • 9
    • 77958611660 scopus 로고    scopus 로고
    • Peripheral CD4+ T-cell differentiation regulated by networks of cytokines and transcription factors
    • Zhu J, Paul WE. Peripheral CD4+ T-cell differentiation regulated by networks of cytokines and transcription factors. Immunol Rev (2010) 238(1):247-62. doi:10.1111/j.1600-065X.2010.00951.x.
    • (2010) Immunol Rev , vol.238 , Issue.1 , pp. 247-262
    • Zhu, J.1    Paul, W.E.2
  • 10
    • 84879211454 scopus 로고    scopus 로고
    • T-cell memory differentiation: insights from transcriptional signatures and epigenetics
    • Youngblood B, Hale JS, Ahmed R. T-cell memory differentiation: insights from transcriptional signatures and epigenetics. Immunology (2013) 139(3):277-84. doi:10.1111/imm.12074.
    • (2013) Immunology , vol.139 , Issue.3 , pp. 277-284
    • Youngblood, B.1    Hale, J.S.2    Ahmed, R.3
  • 11
    • 84874296434 scopus 로고    scopus 로고
    • Defining the molecular blueprint that drives CD8(+) T cell differentiation in response to infection
    • Russ BE, Denton AE, Hatton L, Croom H, Olson MR, Turner SJ. Defining the molecular blueprint that drives CD8(+) T cell differentiation in response to infection. Front Immunol (2012) 3:371. doi:10.3389/fimmu.2012.00371.
    • (2012) Front Immunol , vol.3 , pp. 371
    • Russ, B.E.1    Denton, A.E.2    Hatton, L.3    Croom, H.4    Olson, M.R.5    Turner, S.J.6
  • 12
    • 84890264542 scopus 로고    scopus 로고
    • T cell immunity as a tool for studying epigenetic regulation of cellular differentiation
    • Russ BE, Prier JE, Rao S, Turner SJ. T cell immunity as a tool for studying epigenetic regulation of cellular differentiation. Front Genet (2013) 4:218. doi:10.3389/fgene.2013.00218.
    • (2013) Front Genet , vol.4 , pp. 218
    • Russ, B.E.1    Prier, J.E.2    Rao, S.3    Turner, S.J.4
  • 13
    • 39749145198 scopus 로고    scopus 로고
    • Dynamic regulation of nucleosome positioning in the human genome
    • Schones DE, Cui K, Cuddapah S, Roh TY, Barski A, Wang Z, et al. Dynamic regulation of nucleosome positioning in the human genome. Cell (2008) 132(5):887-98. doi:10.1016/j.cell.2008.02.022.
    • (2008) Cell , vol.132 , Issue.5 , pp. 887-898
    • Schones, D.E.1    Cui, K.2    Cuddapah, S.3    Roh, T.Y.4    Barski, A.5    Wang, Z.6
  • 14
    • 77950262538 scopus 로고    scopus 로고
    • Nucleosome dynamics define transcriptional enhancers
    • He HH, Meyer CA, Shin H, Bailey ST, Wei G, Wang Q, et al. Nucleosome dynamics define transcriptional enhancers. Nat Genet (2010) 42(4):343-7. doi:10.1038/ng.545.
    • (2010) Nat Genet , vol.42 , Issue.4 , pp. 343-347
    • He, H.H.1    Meyer, C.A.2    Shin, H.3    Bailey, S.T.4    Wei, G.5    Wang, Q.6
  • 15
    • 0036091330 scopus 로고    scopus 로고
    • Nucleosome remodeling by the human SWI/SNF complex requires transient global disruption of histone-DNA interactions
    • Aoyagi S, Narlikar G, Zheng C, Sif S, Kingston RE, Hayes JJ. Nucleosome remodeling by the human SWI/SNF complex requires transient global disruption of histone-DNA interactions. Mol Cell Biol (2002) 22(11):3653-62. doi:10.1128/MCB.22.11.3653-3662.2002.
    • (2002) Mol Cell Biol , vol.22 , Issue.11 , pp. 3653-3662
    • Aoyagi, S.1    Narlikar, G.2    Zheng, C.3    Sif, S.4    Kingston, R.E.5    Hayes, J.J.6
  • 16
    • 51149107006 scopus 로고    scopus 로고
    • Regulation of muscle development by DPF3, a novel histone acetylation and methylation reader of the BAF chromatin remodeling complex
    • Lange M, Kaynak B, Forster UB, Tonjes M, Fischer JJ, Grimm C, et al. Regulation of muscle development by DPF3, a novel histone acetylation and methylation reader of the BAF chromatin remodeling complex. Genes Dev (2008) 22(17):2370-84. doi:10.1101/gad.471408.
    • (2008) Genes Dev , vol.22 , Issue.17 , pp. 2370-2384
    • Lange, M.1    Kaynak, B.2    Forster, U.B.3    Tonjes, M.4    Fischer, J.J.5    Grimm, C.6
  • 17
    • 77954487796 scopus 로고    scopus 로고
    • Mechanism and regulation of acetylated histone binding by the tandem PHD finger of DPF3b
    • Zeng L, Zhang Q, Li S, Plotnikov AN, Walsh MJ, Zhou MM. Mechanism and regulation of acetylated histone binding by the tandem PHD finger of DPF3b. Nature (2010) 466(7303):258-62. doi:10.1038/nature09139.
    • (2010) Nature , vol.466 , Issue.7303 , pp. 258-262
    • Zeng, L.1    Zhang, Q.2    Li, S.3    Plotnikov, A.N.4    Walsh, M.J.5    Zhou, M.M.6
  • 18
    • 77954218952 scopus 로고    scopus 로고
    • Structure and function of SWI/SNF chromatin remodeling complexes and mechanistic implications for transcription
    • Tang L, Nogales E, Ciferri C. Structure and function of SWI/SNF chromatin remodeling complexes and mechanistic implications for transcription. Prog Biophys Mol Biol (2010) 102(2-3):122-8. doi:10.1016/j.pbiomolbio.2010.05.001.
    • (2010) Prog Biophys Mol Biol , vol.102 , Issue.2-3 , pp. 122-128
    • Tang, L.1    Nogales, E.2    Ciferri, C.3
  • 19
    • 46249112085 scopus 로고    scopus 로고
    • Combinatorial patterns of histone acetylations and methylations in the human genome
    • Wang Z, Zang C, Rosenfeld JA, Schones DE, Barski A, Cuddapah S, et al. Combinatorial patterns of histone acetylations and methylations in the human genome. Nat Genet (2008) 40(7):897-903. doi:10.1038/ng.154.
    • (2008) Nat Genet , vol.40 , Issue.7 , pp. 897-903
    • Wang, Z.1    Zang, C.2    Rosenfeld, J.A.3    Schones, D.E.4    Barski, A.5    Cuddapah, S.6
  • 20
    • 84888001513 scopus 로고    scopus 로고
    • A new world of polycombs: unexpected partnerships and emerging functions
    • Schwartz YB, Pirrotta V. A new world of polycombs: unexpected partnerships and emerging functions. Nat Rev Genet (2013) 14(12):853-64. doi:10.1038/nrg3603.
    • (2013) Nat Rev Genet , vol.14 , Issue.12 , pp. 853-864
    • Schwartz, Y.B.1    Pirrotta, V.2
  • 21
    • 35148867907 scopus 로고    scopus 로고
    • UTX and JMJD3 are histone H3K27 demethylases involved in HOX gene regulation and development
    • Agger K, Cloos PA, Christensen J, Pasini D, Rose S, Rappsilber J, et al. UTX and JMJD3 are histone H3K27 demethylases involved in HOX gene regulation and development. Nature (2007) 449(7163):731-4. doi:10.1038/nature06145.
    • (2007) Nature , vol.449 , Issue.7163 , pp. 731-734
    • Agger, K.1    Cloos, P.A.2    Christensen, J.3    Pasini, D.4    Rose, S.5    Rappsilber, J.6
  • 22
    • 43249102851 scopus 로고    scopus 로고
    • Erasing the methyl mark: histone demethylases at the center of cellular differentiation and disease
    • Cloos PA, Christensen J, Agger K, Helin K. Erasing the methyl mark: histone demethylases at the center of cellular differentiation and disease. Genes Dev (2008) 22(9):1115-40. doi:10.1101/gad.1652908.
    • (2008) Genes Dev , vol.22 , Issue.9 , pp. 1115-1140
    • Cloos, P.A.1    Christensen, J.2    Agger, K.3    Helin, K.4
  • 23
    • 58149214356 scopus 로고    scopus 로고
    • Global mapping of H3K4me3 and H3K27me3 reveals specificity and plasticity in lineage fate determination of differentiating CD4+ T cells
    • Wei G, Wei L, Zhu J, Zang C, Hu-Li J, Yao Z, et al. Global mapping of H3K4me3 and H3K27me3 reveals specificity and plasticity in lineage fate determination of differentiating CD4+ T cells. Immunity (2009) 30(1):155-67. doi:10.1016/j.immuni.2008.12.009.
    • (2009) Immunity , vol.30 , Issue.1 , pp. 155-167
    • Wei, G.1    Wei, L.2    Zhu, J.3    Zang, C.4    Hu-Li, J.5    Yao, Z.6
  • 25
    • 84874194072 scopus 로고    scopus 로고
    • DNA methylation: roles in mammalian development
    • Smith ZD, Meissner A. DNA methylation: roles in mammalian development. Nat Rev Genet (2013) 14(3):204-20. doi:10.1038/nrg3354.
    • (2013) Nat Rev Genet , vol.14 , Issue.3 , pp. 204-220
    • Smith, Z.D.1    Meissner, A.2
  • 26
    • 0024673303 scopus 로고
    • CpG methylation of the cAMP-responsive enhancer/promoter sequence TGACGTCA abolishes specific factor binding as well as transcriptional activation
    • Iguchi-Ariga SM, Schaffner W. CpG methylation of the cAMP-responsive enhancer/promoter sequence TGACGTCA abolishes specific factor binding as well as transcriptional activation. Genes Dev (1989) 3(5):612-9. doi:10.1101/gad.3.5.612.
    • (1989) Genes Dev , vol.3 , Issue.5 , pp. 612-619
    • Iguchi-Ariga, S.M.1    Schaffner, W.2
  • 27
    • 76749133610 scopus 로고    scopus 로고
    • Role of conserved non-coding DNA elements in the Foxp3 gene in regulatory T-cell fate
    • Zheng Y, Josefowicz S, Chaudhry A, Peng XP, Forbush K, Rudensky AY. Role of conserved non-coding DNA elements in the Foxp3 gene in regulatory T-cell fate. Nature (2010) 463(7282):808-12. doi:10.1038/nature08750.
    • (2010) Nature , vol.463 , Issue.7282 , pp. 808-812
    • Zheng, Y.1    Josefowicz, S.2    Chaudhry, A.3    Peng, X.P.4    Forbush, K.5    Rudensky, A.Y.6
  • 28
    • 0035312289 scopus 로고    scopus 로고
    • The MeCP1 complex represses transcription through preferential binding, remodeling, and deacetylating methylated nucleosomes
    • Feng Q, Zhang Y. The MeCP1 complex represses transcription through preferential binding, remodeling, and deacetylating methylated nucleosomes. Genes Dev (2001) 15(7):827-32. doi:10.1101/gad.876201.
    • (2001) Genes Dev , vol.15 , Issue.7 , pp. 827-832
    • Feng, Q.1    Zhang, Y.2
  • 29
    • 0031837109 scopus 로고    scopus 로고
    • Methylated DNA and MeCP2 recruit histone deacetylase to repress transcription
    • Jones PL, Veenstra GJ, Wade PA, Vermaak D, Kass SU, Landsberger N, et al. Methylated DNA and MeCP2 recruit histone deacetylase to repress transcription. Nat Genet (1998) 19(2):187-91. doi:10.1038/561.
    • (1998) Nat Genet , vol.19 , Issue.2 , pp. 187-191
    • Jones, P.L.1    Veenstra, G.J.2    Wade, P.A.3    Vermaak, D.4    Kass, S.U.5    Landsberger, N.6
  • 30
    • 18944404300 scopus 로고    scopus 로고
    • The thymine DNA glycosylase MBD4 represses transcription and is associated with methylated p16(INK4a) and hMLH1 genes
    • Kondo E, Gu Z, Horii A, Fukushige S. The thymine DNA glycosylase MBD4 represses transcription and is associated with methylated p16(INK4a) and hMLH1 genes. Mol Cell Biol (2005) 25(11):4388-96. doi:10.1128/MCB.25.11.4388-4396.2005.
    • (2005) Mol Cell Biol , vol.25 , Issue.11 , pp. 4388-4396
    • Kondo, E.1    Gu, Z.2    Horii, A.3    Fukushige, S.4
  • 31
    • 65549104157 scopus 로고    scopus 로고
    • Histone modifications at human enhancers reflect global cell-type-specific gene expression
    • Heintzman ND, Hon GC, Hawkins RD, Kheradpour P, Stark A, Harp LF, et al. Histone modifications at human enhancers reflect global cell-type-specific gene expression. Nature (2009) 459(7243):108-12. doi:10.1038/nature07829.
    • (2009) Nature , vol.459 , Issue.7243 , pp. 108-112
    • Heintzman, N.D.1    Hon, G.C.2    Hawkins, R.D.3    Kheradpour, P.4    Stark, A.5    Harp, L.F.6
  • 32
    • 84923796255 scopus 로고    scopus 로고
    • Gene regulation. Transcribed enhancers lead waves of coordinated transcription in transitioning mammalian cells
    • Arner E, Daub CO, Vitting-Seerup K, Andersson R, Lilje B, Drablos F, et al. Gene regulation. Transcribed enhancers lead waves of coordinated transcription in transitioning mammalian cells. Science (2015) 347(6225):1010-4. doi:10.1126/science.1259418.
    • (2015) Science , vol.347 , Issue.6225 , pp. 1010-1014
    • Arner, E.1    Daub, C.O.2    Vitting-Seerup, K.3    Andersson, R.4    Lilje, B.5    Drablos, F.6
  • 33
    • 84862489540 scopus 로고    scopus 로고
    • Dynamic epigenetic enhancer signatures reveal key transcription factors associated with monocytic differentiation states
    • Pham TH, Benner C, Lichtinger M, Schwarzfischer L, Hu Y, Andreesen R, et al. Dynamic epigenetic enhancer signatures reveal key transcription factors associated with monocytic differentiation states. Blood (2012) 119(24):e161-71. doi:10.1182/blood-2012-01-402453.
    • (2012) Blood , vol.119 , Issue.24 , pp. e161-e171
    • Pham, T.H.1    Benner, C.2    Lichtinger, M.3    Schwarzfischer, L.4    Hu, Y.5    Andreesen, R.6
  • 34
    • 84860443136 scopus 로고    scopus 로고
    • Enhancers: emerging roles in cell fate specification
    • Ong CT, Corces VG. Enhancers: emerging roles in cell fate specification. EMBO Rep (2012) 13(5):423-30. doi:10.1038/embor.2012.52.
    • (2012) EMBO Rep , vol.13 , Issue.5 , pp. 423-430
    • Ong, C.T.1    Corces, V.G.2
  • 35
    • 84891347416 scopus 로고    scopus 로고
    • Recessive mutations in a distal PTF1A enhancer cause isolated pancreatic agenesis
    • Weedon MN, Cebola I, Patch AM, Flanagan SE, De Franco E, Caswell R, et al. Recessive mutations in a distal PTF1A enhancer cause isolated pancreatic agenesis. Nat Genet (2014) 46(1):61-4. doi:10.1038/ng.2826.
    • (2014) Nat Genet , vol.46 , Issue.1 , pp. 61-64
    • Weedon, M.N.1    Cebola, I.2    Patch, A.M.3    Flanagan, S.E.4    De Franco, E.5    Caswell, R.6
  • 36
    • 0025108409 scopus 로고
    • Site-directed mutagenesis reveals a liver transcription factor essential for the albumin transcriptional enhancer
    • Zaret KS, Liu JK, DiPersio CM. Site-directed mutagenesis reveals a liver transcription factor essential for the albumin transcriptional enhancer. Proc Natl Acad Sci U S A (1990) 87(14):5469-73. doi:10.1073/pnas.87.14.5469.
    • (1990) Proc Natl Acad Sci U S A , vol.87 , Issue.14 , pp. 5469-5473
    • Zaret, K.S.1    Liu, J.K.2    DiPersio, C.M.3
  • 37
    • 0025800127 scopus 로고
    • Site-directed mutagenesis of hepatocyte nuclear factor (HNF) binding sites in the mouse transthyretin (TTR) promoter reveal synergistic interactions with its enhancer region
    • Costa RH, Grayson DR. Site-directed mutagenesis of hepatocyte nuclear factor (HNF) binding sites in the mouse transthyretin (TTR) promoter reveal synergistic interactions with its enhancer region. Nucleic Acids Res (1991) 19(15):4139-45. doi:10.1093/nar/19.15.4139.
    • (1991) Nucleic Acids Res , vol.19 , Issue.15 , pp. 4139-4145
    • Costa, R.H.1    Grayson, D.R.2
  • 38
    • 84923786414 scopus 로고    scopus 로고
    • The selection and function of cell type-specific enhancers
    • Heinz S, Romanoski CE, Benner C, Glass CK. The selection and function of cell type-specific enhancers. Nat Rev Mol Cell Biol (2015) 16(3):144-54. doi:10.1038/nrm3949.
    • (2015) Nat Rev Mol Cell Biol , vol.16 , Issue.3 , pp. 144-154
    • Heinz, S.1    Romanoski, C.E.2    Benner, C.3    Glass, C.K.4
  • 39
    • 33847334699 scopus 로고    scopus 로고
    • Distinct and predictive chromatin signatures of transcriptional promoters and enhancers in the human genome
    • Heintzman ND, Stuart RK, Hon G, Fu Y, Ching CW, Hawkins RD, et al. Distinct and predictive chromatin signatures of transcriptional promoters and enhancers in the human genome. Nat Genet (2007) 39(3):311-8. doi:10.1038/ng1966.
    • (2007) Nat Genet , vol.39 , Issue.3 , pp. 311-318
    • Heintzman, N.D.1    Stuart, R.K.2    Hon, G.3    Fu, Y.4    Ching, C.W.5    Hawkins, R.D.6
  • 40
    • 80051564877 scopus 로고    scopus 로고
    • Epigenetic signatures distinguish multiple classes of enhancers with distinct cellular functions
    • Zentner GE, Tesar PJ, Scacheri PC. Epigenetic signatures distinguish multiple classes of enhancers with distinct cellular functions. Genome Res (2011) 21(8):1273-83. doi:10.1101/gr.122382.111.
    • (2011) Genome Res , vol.21 , Issue.8 , pp. 1273-1283
    • Zentner, G.E.1    Tesar, P.J.2    Scacheri, P.C.3
  • 41
  • 42
    • 79951516056 scopus 로고    scopus 로고
    • A unique chromatin signature uncovers early developmental enhancers in humans
    • Rada-Iglesias A, Bajpai R, Swigut T, Brugmann SA, Flynn RA, Wysocka J. A unique chromatin signature uncovers early developmental enhancers in humans. Nature (2011) 470(7333):279-83. doi:10.1038/nature09692.
    • (2011) Nature , vol.470 , Issue.7333 , pp. 279-283
    • Rada-Iglesias, A.1    Bajpai, R.2    Swigut, T.3    Brugmann, S.A.4    Flynn, R.A.5    Wysocka, J.6
  • 43
    • 33646070846 scopus 로고    scopus 로고
    • A bivalent chromatin structure marks key developmental genes in embryonic stem cells
    • Bernstein BE, Mikkelsen TS, Xie X, Kamal M, Huebert DJ, CuffJ, et al. A bivalent chromatin structure marks key developmental genes in embryonic stem cells. Cell (2006) 125(2):315-26. doi:10.1016/j.cell.2006.02.041.
    • (2006) Cell , vol.125 , Issue.2 , pp. 315-326
    • Bernstein, B.E.1    Mikkelsen, T.S.2    Xie, X.3    Kamal, M.4    Huebert, D.J.5    Cuff, J.6
  • 44
    • 84870027825 scopus 로고    scopus 로고
    • STATs shape the active enhancer landscape of T cell populations
    • Vahedi G, Takahashi H, Nakayamada S, Sun HW, Sartorelli V, Kanno Y, et al. STATs shape the active enhancer landscape of T cell populations. Cell (2012) 151(5):981-93. doi:10.1016/j.cell.2012.09.044.
    • (2012) Cell , vol.151 , Issue.5 , pp. 981-993
    • Vahedi, G.1    Takahashi, H.2    Nakayamada, S.3    Sun, H.W.4    Sartorelli, V.5    Kanno, Y.6
  • 45
    • 79952267284 scopus 로고    scopus 로고
    • High-resolution genome-wide in vivo footprinting of diverse transcription factors in human cells
    • Boyle AP, Song L, Lee BK, London D, Keefe D, Birney E, et al. High-resolution genome-wide in vivo footprinting of diverse transcription factors in human cells. Genome Res (2011) 21(3):456-64. doi:10.1101/gr.112656.110.
    • (2011) Genome Res , vol.21 , Issue.3 , pp. 456-464
    • Boyle, A.P.1    Song, L.2    Lee, B.K.3    London, D.4    Keefe, D.5    Birney, E.6
  • 46
    • 0018199224 scopus 로고
    • DNAse footprinting: a simple method for the detection of protein-DNA binding specificity
    • Galas DJ, Schmitz A. DNAse footprinting: a simple method for the detection of protein-DNA binding specificity. Nucleic Acids Res (1978) 5(9):3157-70. doi:10.1093/nar/5.9.3157.
    • (1978) Nucleic Acids Res , vol.5 , Issue.9 , pp. 3157-3170
    • Galas, D.J.1    Schmitz, A.2
  • 47
    • 77956276383 scopus 로고    scopus 로고
    • DNase-seq: a high-resolution technique for mapping active gene regulatory elements across the genome from mammalian cells
    • Song L, Crawford GE. DNase-seq: a high-resolution technique for mapping active gene regulatory elements across the genome from mammalian cells. Cold Spring Harb Protoc (2010) 2010(2):1-11. doi:10.1101/pdb.prot5384.
    • (2010) Cold Spring Harb Protoc , vol.2010 , Issue.2 , pp. 1-11
    • Song, L.1    Crawford, G.E.2
  • 48
    • 84888877924 scopus 로고    scopus 로고
    • Transposition of native chromatin for fast and sensitive epigenomic profiling of open chromatin, DNA-binding proteins and nucleosome position
    • Buenrostro JD, Giresi PG, Zaba LC, Chang HY, Greenleaf WJ. Transposition of native chromatin for fast and sensitive epigenomic profiling of open chromatin, DNA-binding proteins and nucleosome position. Nat Methods (2013) 10(12):1213-8. doi:10.1038/nmeth.2688.
    • (2013) Nat Methods , vol.10 , Issue.12 , pp. 1213-1218
    • Buenrostro, J.D.1    Giresi, P.G.2    Zaba, L.C.3    Chang, H.Y.4    Greenleaf, W.J.5
  • 49
    • 0037083376 scopus 로고    scopus 로고
    • Capturing chromosome conformation
    • Dekker J, Rippe K, Dekker M, Kleckner N. Capturing chromosome conformation. Science (2002) 295(5558):1306-11. doi:10.1126/science.1067799.
    • (2002) Science , vol.295 , Issue.5558 , pp. 1306-1311
    • Dekker, J.1    Rippe, K.2    Dekker, M.3    Kleckner, N.4
  • 50
    • 70349873824 scopus 로고    scopus 로고
    • Comprehensive mapping of long-range interactions reveals folding principles of the human genome
    • Lieberman-Aiden E, van Berkum NL, Williams L, Imakaev M, Ragoczy T, Telling A, et al. Comprehensive mapping of long-range interactions reveals folding principles of the human genome. Science (2009) 326(5950):289-93. doi:10.1126/science.1181369.
    • (2009) Science , vol.326 , Issue.5950 , pp. 289-293
    • Lieberman-Aiden, E.1    van Berkum, N.L.2    Williams, L.3    Imakaev, M.4    Ragoczy, T.5    Telling, A.6
  • 51
    • 34548565667 scopus 로고    scopus 로고
    • Quantitative analysis of chromosome conformation capture assays (3C-qPCR)
    • Hagege H, Klous P, Braem C, Splinter E, Dekker J, Cathala G, et al. Quantitative analysis of chromosome conformation capture assays (3C-qPCR). Nat Protoc (2007) 2(7):1722-33. doi:10.1038/nprot.2007.243.
    • (2007) Nat Protoc , vol.2 , Issue.7 , pp. 1722-1733
    • Hagege, H.1    Klous, P.2    Braem, C.3    Splinter, E.4    Dekker, J.5    Cathala, G.6
  • 52
    • 9144233601 scopus 로고    scopus 로고
    • Cap analysis gene expression for high-throughput analysis of transcriptional starting point and identification of promoter usage
    • Shiraki T, Kondo S, Katayama S, Waki K, Kasukawa T, Kawaji H, et al. Cap analysis gene expression for high-throughput analysis of transcriptional starting point and identification of promoter usage. Proc Natl Acad Sci U S A (2003) 100(26):15776-81. doi:10.1073/pnas.2136655100.
    • (2003) Proc Natl Acad Sci U S A , vol.100 , Issue.26 , pp. 15776-15781
    • Shiraki, T.1    Kondo, S.2    Katayama, S.3    Waki, K.4    Kasukawa, T.5    Kawaji, H.6
  • 53
    • 33750465872 scopus 로고    scopus 로고
    • SATB1 packages densely looped, transcriptionally active chromatin for coordinated expression of cytokine genes
    • Cai S, Lee CC, Kohwi-Shigematsu T. SATB1 packages densely looped, transcriptionally active chromatin for coordinated expression of cytokine genes. Nat Genet (2006) 38(11):1278-88. doi:10.1038/ng1913.
    • (2006) Nat Genet , vol.38 , Issue.11 , pp. 1278-1288
    • Cai, S.1    Lee, C.C.2    Kohwi-Shigematsu, T.3
  • 54
    • 12344250807 scopus 로고    scopus 로고
    • Hypersensitive site 7 of the TH2 locus control region is essential for expressing TH2 cytokine genes and for long-range intrachromosomal interactions
    • Lee GR, Spilianakis CG, Flavell RA. Hypersensitive site 7 of the TH2 locus control region is essential for expressing TH2 cytokine genes and for long-range intrachromosomal interactions. Nat Immunol (2005) 6(1):42-8. doi:10.1038/ni1148.
    • (2005) Nat Immunol , vol.6 , Issue.1 , pp. 42-48
    • Lee, G.R.1    Spilianakis, C.G.2    Flavell, R.A.3
  • 55
    • 5444237577 scopus 로고    scopus 로고
    • Long-range intrachromosomal interactions in the T helper type 2 cytokine locus
    • Spilianakis CG, Flavell RA. Long-range intrachromosomal interactions in the T helper type 2 cytokine locus. Nat Immunol (2004) 5(10):1017-27. doi:10.1038/ni1115.
    • (2004) Nat Immunol , vol.5 , Issue.10 , pp. 1017-1027
    • Spilianakis, C.G.1    Flavell, R.A.2
  • 56
    • 78650304399 scopus 로고    scopus 로고
    • The enhancer HS2 critically regulates GATA-3-mediated Il4 transcription in T(H)2 cells
    • Tanaka S, Motomura Y, Suzuki Y, Yagi R, Inoue H, Miyatake S, et al. The enhancer HS2 critically regulates GATA-3-mediated Il4 transcription in T(H)2 cells. Nat Immunol (2011) 12(1):77-85. doi:10.1038/ni.1966.
    • (2011) Nat Immunol , vol.12 , Issue.1 , pp. 77-85
    • Tanaka, S.1    Motomura, Y.2    Suzuki, Y.3    Yagi, R.4    Inoue, H.5    Miyatake, S.6
  • 57
    • 0032412441 scopus 로고    scopus 로고
    • Modulation of chromatin structure regulates cytokine gene expression during T cell differentiation
    • Agarwal S, Rao A. Modulation of chromatin structure regulates cytokine gene expression during T cell differentiation. Immunity (1998) 9(6):765-75. doi:10.1016/S1074-7613(00)80642-1.
    • (1998) Immunity , vol.9 , Issue.6 , pp. 765-775
    • Agarwal, S.1    Rao, A.2
  • 58
    • 0031593671 scopus 로고    scopus 로고
    • Th2-specific DNase I-hypersensitive sites in the murine IL-13 and IL-4 intergenic region
    • Takemoto N, Koyano-Nakagawa N, Yokota T, Arai N, Miyatake S, Arai K. Th2-specific DNase I-hypersensitive sites in the murine IL-13 and IL-4 intergenic region. Int Immunol (1998) 10(12):1981-5. doi:10.1093/intimm/10.12.1981.
    • (1998) Int Immunol , vol.10 , Issue.12 , pp. 1981-1985
    • Takemoto, N.1    Koyano-Nakagawa, N.2    Yokota, T.3    Arai, N.4    Miyatake, S.5    Arai, K.6
  • 59
    • 0033667895 scopus 로고    scopus 로고
    • Cell-type-restricted binding of the transcription factor NFAT to a distal IL-4 enhancer in vivo
    • Agarwal S, Avni O, Rao A. Cell-type-restricted binding of the transcription factor NFAT to a distal IL-4 enhancer in vivo. Immunity (2000) 12(6):643-52. doi:10.1016/S1074-7613(00)80215-0.
    • (2000) Immunity , vol.12 , Issue.6 , pp. 643-652
    • Agarwal, S.1    Avni, O.2    Rao, A.3
  • 60
    • 84875279735 scopus 로고    scopus 로고
    • Functionally distinct Gata3/Chd4 complexes coordinately establish T helper 2 (Th2) cell identity
    • Hosokawa H, Tanaka T, Suzuki Y, Iwamura C, Ohkubo S, Endoh K, et al. Functionally distinct Gata3/Chd4 complexes coordinately establish T helper 2 (Th2) cell identity. Proc Natl Acad Sci U S A (2013) 110(12):4691-6. doi:10.1073/pnas.1220865110.
    • (2013) Proc Natl Acad Sci U S A , vol.110 , Issue.12 , pp. 4691-4696
    • Hosokawa, H.1    Tanaka, T.2    Suzuki, Y.3    Iwamura, C.4    Ohkubo, S.5    Endoh, K.6
  • 61
    • 84863393256 scopus 로고    scopus 로고
    • Interleukin-4 production by follicular helper T cells requires the conserved Il4 enhancer hypersensitivity site V
    • Vijayanand P, Seumois G, Simpson LJ, Abdul-Wajid S, Baumjohann D, Panduro M, et al. Interleukin-4 production by follicular helper T cells requires the conserved Il4 enhancer hypersensitivity site V. Immunity (2012) 36(2):175-87. doi:10.1016/j.immuni.2011.12.014.
    • (2012) Immunity , vol.36 , Issue.2 , pp. 175-187
    • Vijayanand, P.1    Seumois, G.2    Simpson, L.J.3    Abdul-Wajid, S.4    Baumjohann, D.5    Panduro, M.6
  • 62
    • 70349756895 scopus 로고    scopus 로고
    • CCCTC-binding factor and the transcription factor T-bet orchestrate T helper 1 cell-specific structure and function at the interferon-gamma locus
    • Sekimata M, Perez-Melgosa M, Miller SA, Weinmann AS, Sabo PJ, Sandstrom R, et al. CCCTC-binding factor and the transcription factor T-bet orchestrate T helper 1 cell-specific structure and function at the interferon-gamma locus. Immunity (2009) 31(4):551-64. doi:10.1016/j.immuni.2009.08.021.
    • (2009) Immunity , vol.31 , Issue.4 , pp. 551-564
    • Sekimata, M.1    Perez-Melgosa, M.2    Miller, S.A.3    Weinmann, A.S.4    Sabo, P.J.5    Sandstrom, R.6
  • 63
    • 77958572323 scopus 로고    scopus 로고
    • Regulation of the Ifng locus in the context of T-lineage specification and plasticity
    • Balasubramani A, Mukasa R, Hatton RD, Weaver CT. Regulation of the Ifng locus in the context of T-lineage specification and plasticity. Immunol Rev (2010) 238(1):216-32. doi:10.1111/j.1600-065X.2010.00961.x.
    • (2010) Immunol Rev , vol.238 , Issue.1 , pp. 216-232
    • Balasubramani, A.1    Mukasa, R.2    Hatton, R.D.3    Weaver, C.T.4
  • 64
    • 0034677646 scopus 로고    scopus 로고
    • A novel transcription factor, T-bet, directs Th1 lineage commitment
    • Szabo SJ, Kim ST, Costa GL, Zhang X, Fathman CG, Glimcher LH. A novel transcription factor, T-bet, directs Th1 lineage commitment. Cell (2000) 100(6):655-69. doi:10.1016/S0092-8674(00)80702-3.
    • (2000) Cell , vol.100 , Issue.6 , pp. 655-669
    • Szabo, S.J.1    Kim, S.T.2    Costa, G.L.3    Zhang, X.4    Fathman, C.G.5    Glimcher, L.H.6
  • 65
    • 84896699887 scopus 로고    scopus 로고
    • Deletion of a conserved cis-element in the Ifng locus highlights the role of acute histone acetylation in modulating inducible gene transcription
    • Balasubramani A, Winstead CJ, Turner H, Janowski KM, Harbour SN, Shibata Y, et al. Deletion of a conserved cis-element in the Ifng locus highlights the role of acute histone acetylation in modulating inducible gene transcription. PLoS Genet (2014) 10(1):e1003969. doi:10.1371/journal.pgen.1003969.
    • (2014) PLoS Genet , vol.10 , Issue.1
    • Balasubramani, A.1    Winstead, C.J.2    Turner, H.3    Janowski, K.M.4    Harbour, S.N.5    Shibata, Y.6
  • 66
    • 77956420485 scopus 로고    scopus 로고
    • Distal regions of the human IFNG locus direct cell type-specific expression
    • Collins PL, Chang S, Henderson M, Soutto M, Davis GM, McLoed AG, et al. Distal regions of the human IFNG locus direct cell type-specific expression. J Immunol (2010) 185(3):1492-501. doi:10.4049/jimmunol.1000124.
    • (2010) J Immunol , vol.185 , Issue.3 , pp. 1492-1501
    • Collins, P.L.1    Chang, S.2    Henderson, M.3    Soutto, M.4    Davis, G.M.5    McLoed, A.G.6
  • 67
    • 84856913512 scopus 로고    scopus 로고
    • Diverse functions of distal regulatory elements at the IFNG locus
    • Collins PL, Henderson MA, Aune TM. Diverse functions of distal regulatory elements at the IFNG locus. J Immunol (2012) 188(4):1726-33. doi:10.4049/jimmunol.1102879.
    • (2012) J Immunol , vol.188 , Issue.4 , pp. 1726-1733
    • Collins, P.L.1    Henderson, M.A.2    Aune, T.M.3
  • 68
    • 84889881019 scopus 로고    scopus 로고
    • Transcriptional control of CD4 and CD8 coreceptor expression during T cell development
    • Ellmeier W, Haust L, Tschismarov R. Transcriptional control of CD4 and CD8 coreceptor expression during T cell development. Cell Mol Life Sci (2013) 70(23):4537-53. doi:10.1007/s00018-013-1393-2.
    • (2013) Cell Mol Life Sci , vol.70 , Issue.23 , pp. 4537-4553
    • Ellmeier, W.1    Haust, L.2    Tschismarov, R.3
  • 69
    • 0032191963 scopus 로고    scopus 로고
    • Multiple developmental stage-specific enhancers regulate CD8 expression in developing thymocytes and in thymus-independent T cells
    • Ellmeier W, Sunshine MJ, Losos K, Littman DR. Multiple developmental stage-specific enhancers regulate CD8 expression in developing thymocytes and in thymus-independent T cells. Immunity (1998) 9(4):485-96. doi:10.1016/S1074-7613(00)80632-9.
    • (1998) Immunity , vol.9 , Issue.4 , pp. 485-496
    • Ellmeier, W.1    Sunshine, M.J.2    Losos, K.3    Littman, D.R.4
  • 70
    • 81055130116 scopus 로고    scopus 로고
    • Cd8 enhancer E8I and Runx factors regulate CD8alpha expression in activated CD8+ T cells
    • Hassan H, Sakaguchi S, Tenno M, Kopf A, Boucheron N, Carpenter AC, et al. Cd8 enhancer E8I and Runx factors regulate CD8alpha expression in activated CD8+ T cells. Proc Natl Acad Sci U S A (2011) 108(45):18330-5. doi:10.1073/pnas.1105835108.
    • (2011) Proc Natl Acad Sci U S A , vol.108 , Issue.45 , pp. 18330-18335
    • Hassan, H.1    Sakaguchi, S.2    Tenno, M.3    Kopf, A.4    Boucheron, N.5    Carpenter, A.C.6
  • 71
    • 0036285006 scopus 로고    scopus 로고
    • Combined deletion of CD8 locus cis-regulatory elements affects initiation but not maintenance of CD8 expression
    • Ellmeier W, Sunshine MJ, Maschek R, Littman DR. Combined deletion of CD8 locus cis-regulatory elements affects initiation but not maintenance of CD8 expression. Immunity (2002) 16(5):623-34. doi:10.1016/S1074-7613(02)00309-6.
    • (2002) Immunity , vol.16 , Issue.5 , pp. 623-634
    • Ellmeier, W.1    Sunshine, M.J.2    Maschek, R.3    Littman, D.R.4
  • 72
    • 33645107299 scopus 로고    scopus 로고
    • Negative regulation of CD8 expression via Cd8 enhancer-mediated recruitment of the zinc finger protein MAZR
    • Bilic I, Koesters C, Unger B, Sekimata M, Hertweck A, Maschek R, et al. Negative regulation of CD8 expression via Cd8 enhancer-mediated recruitment of the zinc finger protein MAZR. Nat Immunol (2006) 7(4):392-400. doi:10.1038/ni1311.
    • (2006) Nat Immunol , vol.7 , Issue.4 , pp. 392-400
    • Bilic, I.1    Koesters, C.2    Unger, B.3    Sekimata, M.4    Hertweck, A.5    Maschek, R.6
  • 73
    • 84897459921 scopus 로고    scopus 로고
    • Epigenetic plasticity of Cd8a locus during CD8(+) T-cell development and effector differentiation and reprogramming
    • Harland KL, Day EB, Apte SH, Russ BE, Doherty PC, Turner SJ, et al. Epigenetic plasticity of Cd8a locus during CD8(+) T-cell development and effector differentiation and reprogramming. Nat Commun (2014) 5:3547. doi:10.1038/ncomms4547.
    • (2014) Nat Commun , vol.5 , pp. 3547
    • Harland, K.L.1    Day, E.B.2    Apte, S.H.3    Russ, B.E.4    Doherty, P.C.5    Turner, S.J.6
  • 75
    • 79953134246 scopus 로고    scopus 로고
    • Genomic views of STAT function in CD4+ T helper cell differentiation
    • O'Shea JJ, Lahesmaa R, Vahedi G, Laurence A, Kanno Y. Genomic views of STAT function in CD4+ T helper cell differentiation. Nat Rev Immunol (2011) 11(4):239-50. doi:10.1038/nri2958.
    • (2011) Nat Rev Immunol , vol.11 , Issue.4 , pp. 239-250
    • O'Shea, J.J.1    Lahesmaa, R.2    Vahedi, G.3    Laurence, A.4    Kanno, Y.5
  • 76
    • 34249707951 scopus 로고    scopus 로고
    • The chemokine and chemokine receptor superfamilies and their molecular evolution
    • Zlotnik A, Yoshie O, Nomiyama H. The chemokine and chemokine receptor superfamilies and their molecular evolution. Genome Biol (2006) 7(12):243. doi:10.1186/gb-2006-7-12-243.
    • (2006) Genome Biol , vol.7 , Issue.12 , pp. 243
    • Zlotnik, A.1    Yoshie, O.2    Nomiyama, H.3
  • 77
    • 84857781464 scopus 로고    scopus 로고
    • Characterization of genome-wide enhancer-promoter interactions reveals co-expression of interacting genes and modes of higher order chromatin organization
    • Chepelev I, Wei G, Wangsa D, Tang Q, Zhao K. Characterization of genome-wide enhancer-promoter interactions reveals co-expression of interacting genes and modes of higher order chromatin organization. Cell Res (2012) 22(3):490-503. doi:10.1038/cr.2012.15.
    • (2012) Cell Res , vol.22 , Issue.3 , pp. 490-503
    • Chepelev, I.1    Wei, G.2    Wangsa, D.3    Tang, Q.4    Zhao, K.5
  • 78
    • 84862908850 scopus 로고    scopus 로고
    • Extensive promoter-centered chromatin interactions provide a topological basis for transcription regulation
    • Li G, Ruan X, Auerbach RK, Sandhu KS, Zheng M, Wang P, et al. Extensive promoter-centered chromatin interactions provide a topological basis for transcription regulation. Cell (2012) 148(1-2):84-98. doi:10.1016/j.cell.2011.12.014.
    • (2012) Cell , vol.148 , Issue.1-2 , pp. 84-98
    • Li, G.1    Ruan, X.2    Auerbach, R.K.3    Sandhu, K.S.4    Zheng, M.5    Wang, P.6
  • 79
    • 84904644906 scopus 로고    scopus 로고
    • Epigenomic analysis of primary human T cells reveals enhancers associated with TH2 memory cell differentiation and asthma susceptibility
    • Seumois G, Chavez L, Gerasimova A, Lienhard M, Omran N, Kalinke L, et al. Epigenomic analysis of primary human T cells reveals enhancers associated with TH2 memory cell differentiation and asthma susceptibility. Nat Immunol (2014) 15(8):777-88. doi:10.1038/ni.2937.
    • (2014) Nat Immunol , vol.15 , Issue.8 , pp. 777-788
    • Seumois, G.1    Chavez, L.2    Gerasimova, A.3    Lienhard, M.4    Omran, N.5    Kalinke, L.6
  • 80
    • 84928560965 scopus 로고    scopus 로고
    • Super-enhancers delineate disease-associated regulatory nodes in T cells
    • Vahedi G, Kanno Y, Furumoto Y, Jiang K, Parker SC, Erdos MR, et al. Super-enhancers delineate disease-associated regulatory nodes in T cells. Nature (2015) 520(7548):558-62. doi:10.1038/nature14154.
    • (2015) Nature , vol.520 , Issue.7548 , pp. 558-562
    • Vahedi, G.1    Kanno, Y.2    Furumoto, Y.3    Jiang, K.4    Parker, S.C.5    Erdos, M.R.6
  • 81
    • 84925283769 scopus 로고    scopus 로고
    • What are super-enhancers?
    • Pott S, Lieb JD. What are super-enhancers? Nat Genet (2015) 47(1):8-12. doi:10.1038/ng.3167.
    • (2015) Nat Genet , vol.47 , Issue.1 , pp. 8-12
    • Pott, S.1    Lieb, J.D.2
  • 82
    • 84900314611 scopus 로고    scopus 로고
    • CRISPR-Cas systems for editing, regulating and targeting genomes
    • Sander JD, Joung JK. CRISPR-Cas systems for editing, regulating and targeting genomes. Nat Biotechnol (2014) 32(4):347-55. doi:10.1038/nbt.2842.
    • (2014) Nat Biotechnol , vol.32 , Issue.4 , pp. 347-355
    • Sander, J.D.1    Joung, J.K.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.