-
1
-
-
84864118287
-
Immunological complications of obesity
-
Kanneganti TD, Dixit VD., Immunological complications of obesity. Nat Immunol 2012; 13: 707-712.
-
(2012)
Nat Immunol
, vol.13
, pp. 707-712
-
-
Kanneganti, T.D.1
Dixit, V.D.2
-
2
-
-
77951918926
-
Macrophages, inflammation, and insulin resistance
-
Olefsky JM, Glass CK., Macrophages, inflammation, and insulin resistance. Ann Rev Physiol 2010; 72: 219-246.
-
(2010)
Ann Rev Physiol
, vol.72
, pp. 219-246
-
-
Olefsky, J.M.1
Glass, C.K.2
-
3
-
-
33846026712
-
Obesity induces a phenotypic switch in adipose tissue macrophage polarization
-
Lumeng CN, Bodzin JL, Saltiel AR., Obesity induces a phenotypic switch in adipose tissue macrophage polarization. J Clin Investig 2007; 117: 175-184.
-
(2007)
J Clin Investig
, vol.117
, pp. 175-184
-
-
Lumeng, C.N.1
Bodzin, J.L.2
Saltiel, A.R.3
-
4
-
-
68349150756
-
CD8+ effector T cells contribute to macrophage recruitment and adipose tissue inflammation in obesity
-
Nishimura S, Manabe I, Nagasaki M, et al., CD8+ effector T cells contribute to macrophage recruitment and adipose tissue inflammation in obesity. Nat Med 2009; 15: 914-920.
-
(2009)
Nat Med
, vol.15
, pp. 914-920
-
-
Nishimura, S.1
Manabe, I.2
Nagasaki, M.3
-
5
-
-
68349160704
-
Genetic deficiency and pharmacological stabilization of mast cells reduce diet-induced obesity and diabetes in mice
-
Liu J, Divoux A, Sun J, et al., Genetic deficiency and pharmacological stabilization of mast cells reduce diet-induced obesity and diabetes in mice. Nat Med 2009; 15: 940-945.
-
(2009)
Nat Med
, vol.15
, pp. 940-945
-
-
Liu, J.1
Divoux, A.2
Sun, J.3
-
6
-
-
79953815551
-
Eosinophils sustain adipose alternatively activated macrophages associated with glucose homeostasis
-
Wu D, Molofsky AB, Liang HE, et al., Eosinophils sustain adipose alternatively activated macrophages associated with glucose homeostasis. Science 2011; 332: 243-247.
-
(2011)
Science
, vol.332
, pp. 243-247
-
-
Wu, D.1
Molofsky, A.B.2
Liang, H.E.3
-
7
-
-
85027938385
-
B cells promote insulin resistance through modulation of T cells and production of pathogenic IgG antibodies
-
Winer DA, Winer S, Shen L, et al., B cells promote insulin resistance through modulation of T cells and production of pathogenic IgG antibodies. Nat Med 2011; 17: 610-617.
-
(2011)
Nat Med
, vol.17
, pp. 610-617
-
-
Winer, D.A.1
Winer, S.2
Shen, L.3
-
8
-
-
84868671526
-
Neutrophils mediate insulin resistance in mice fed a high-fat diet through secreted elastase
-
Talukdar S, Oh da Y, Bandyopadhyay G, et al., Neutrophils mediate insulin resistance in mice fed a high-fat diet through secreted elastase. Nat Med 2012; 18: 1407-1412.
-
(2012)
Nat Med
, vol.18
, pp. 1407-1412
-
-
Talukdar, S.1
Oh Da, Y.2
Bandyopadhyay, G.3
-
9
-
-
84865992180
-
Natural killer T cells in adipose tissue prevent insulin resistance
-
Schipper HS, Rakhshandehroo M, van de Graaf SF, et al., Natural killer T cells in adipose tissue prevent insulin resistance. J Clin Investig 2012; 122: 3343-3354.
-
(2012)
J Clin Investig
, vol.122
, pp. 3343-3354
-
-
Schipper, H.S.1
Rakhshandehroo, M.2
Van De Graaf, S.F.3
-
10
-
-
84866520055
-
Adipose tissue invariant NKT cells protect against diet-induced obesity and metabolic disorder through regulatory cytokine production
-
Lynch L, Nowak M, Varghese B, et al., Adipose tissue invariant NKT cells protect against diet-induced obesity and metabolic disorder through regulatory cytokine production. Immunity 2012; 37: 574-587.
-
(2012)
Immunity
, vol.37
, pp. 574-587
-
-
Lynch, L.1
Nowak, M.2
Varghese, B.3
-
11
-
-
33847183077
-
Cooperation of Toll-like receptor signals in innate immune defence
-
Trinchieri G, Sher A., Cooperation of Toll-like receptor signals in innate immune defence. Nat Rev Immunol 2007; 7: 179-190.
-
(2007)
Nat Rev Immunol
, vol.7
, pp. 179-190
-
-
Trinchieri, G.1
Sher, A.2
-
12
-
-
77950250064
-
Metabolic syndrome and altered gut microbiota in mice lacking Toll-like receptor 5
-
Vijay-Kumar M, Aitken JD, Carvalho FA, et al., Metabolic syndrome and altered gut microbiota in mice lacking Toll-like receptor 5. Science 2010; 328: 228-231.
-
(2010)
Science
, vol.328
, pp. 228-231
-
-
Vijay-Kumar, M.1
Aitken, J.D.2
Carvalho, F.A.3
-
13
-
-
34547602916
-
Loss-of-function mutation in Toll-like receptor 4 prevents diet-induced obesity and insulin resistance
-
Tsukumo DM, Carvalho-Filho MA, Carvalheira JB, et al., Loss-of-function mutation in Toll-like receptor 4 prevents diet-induced obesity and insulin resistance. Diabetes 2007; 56: 1986-1998.
-
(2007)
Diabetes
, vol.56
, pp. 1986-1998
-
-
Tsukumo, D.M.1
Carvalho-Filho, M.A.2
Carvalheira, J.B.3
-
14
-
-
77952315676
-
Tlr2 is critical for diet-induced metabolic syndrome in a murine model
-
Himes RW, Smith CW., Tlr2 is critical for diet-induced metabolic syndrome in a murine model. FASEB J 2010; 24: 731-739.
-
(2010)
FASEB J
, vol.24
, pp. 731-739
-
-
Himes, R.W.1
Smith, C.W.2
-
15
-
-
0034619794
-
A Toll-like receptor recognizes bacterial DNA
-
Hemmi H, Takeuchi O, Kawai T, et al., A Toll-like receptor recognizes bacterial DNA. Nature 2000; 408: 740-745.
-
(2000)
Nature
, vol.408
, pp. 740-745
-
-
Hemmi, H.1
Takeuchi, O.2
Kawai, T.3
-
16
-
-
12144286763
-
Toll-like receptors 9 and 3 as essential components of innate immune defense against mouse cytomegalovirus infection
-
Tabeta K, Georgel P, Janssen E, et al., Toll-like receptors 9 and 3 as essential components of innate immune defense against mouse cytomegalovirus infection. Proc Natl Acad Sci USA 2004; 101: 3516-3521.
-
(2004)
Proc Natl Acad Sci USA
, vol.101
, pp. 3516-3521
-
-
Tabeta, K.1
Georgel, P.2
Janssen, E.3
-
17
-
-
33846898975
-
Toll-like receptor 9 acts at an early stage in host defence against pneumococcal infection
-
Albiger B, Dahlberg S, Sandgren A, et al., Toll-like receptor 9 acts at an early stage in host defence against pneumococcal infection. Cell Microbiol 2007; 9: 633-644.
-
(2007)
Cell Microbiol
, vol.9
, pp. 633-644
-
-
Albiger, B.1
Dahlberg, S.2
Sandgren, A.3
-
18
-
-
34447128388
-
Antiinfective applications of toll-like receptor 9 agonists
-
Krieg AM., Antiinfective applications of toll-like receptor 9 agonists. Proc Am Thorac Soc 2007; 4: 289-294.
-
(2007)
Proc Am Thorac Soc
, vol.4
, pp. 289-294
-
-
Krieg, A.M.1
-
19
-
-
48549088455
-
Antimicrobial peptides and self-DNA in autoimmune skin inflammation
-
Gilliet M, Lande R., Antimicrobial peptides and self-DNA in autoimmune skin inflammation. Curr Opin Immunol 2008; 20: 401-407.
-
(2008)
Curr Opin Immunol
, vol.20
, pp. 401-407
-
-
Gilliet, M.1
Lande, R.2
-
20
-
-
84866735326
-
TLR7 and TLR9 in SLE: When sensing self goes wrong
-
Celhar T, Magalhaes R, Fairhurst AM., TLR7 and TLR9 in SLE: When sensing self goes wrong. Immunol Res 2012; 53: 58-77.
-
(2012)
Immunol Res
, vol.53
, pp. 58-77
-
-
Celhar, T.1
Magalhaes, R.2
Fairhurst, A.M.3
-
21
-
-
10744233159
-
Toll-like receptor 9 signaling mediates the anti-inflammatory effects of probiotics in murine experimental colitis
-
Rachmilewitz D, Katakura K, Karmeli F, et al., Toll-like receptor 9 signaling mediates the anti-inflammatory effects of probiotics in murine experimental colitis. Gastroenterology 2004; 126: 520-528.
-
(2004)
Gastroenterology
, vol.126
, pp. 520-528
-
-
Rachmilewitz, D.1
Katakura, K.2
Karmeli, F.3
-
22
-
-
84876412015
-
Topical treatment with the Toll-like receptor agonist DIMS0150 has potential for lasting relief of symptoms in patients with chronic active ulcerative colitis by restoring glucocorticoid sensitivity
-
Musch E, Lutfi T, von Stein P, et al., Topical treatment with the Toll-like receptor agonist DIMS0150 has potential for lasting relief of symptoms in patients with chronic active ulcerative colitis by restoring glucocorticoid sensitivity. Inflamm Bowel Dis 2013; 19: 283-292.
-
(2013)
Inflamm Bowel Dis
, vol.19
, pp. 283-292
-
-
Musch, E.1
Lutfi, T.2
Von Stein, P.3
-
23
-
-
33745834319
-
Adiponectin and adiponectin receptors in insulin resistance, diabetes, and the metabolic syndrome
-
Kadowaki T, Yamauchi T, Kubota N, et al., Adiponectin and adiponectin receptors in insulin resistance, diabetes, and the metabolic syndrome. J Clin Investig 2006; 116: 1784-1792.
-
(2006)
J Clin Investig
, vol.116
, pp. 1784-1792
-
-
Kadowaki, T.1
Yamauchi, T.2
Kubota, N.3
-
24
-
-
84903531205
-
CXCL12 secreted from adipose tissue recruits macrophages and induces insulin resistance in mice
-
Kim D, Kim J, Yoon JH, et al., CXCL12 secreted from adipose tissue recruits macrophages and induces insulin resistance in mice. Diabetologia 2014; 57: 1456-1465.
-
(2014)
Diabetologia
, vol.57
, pp. 1456-1465
-
-
Kim, D.1
Kim, J.2
Yoon, J.H.3
-
25
-
-
68349137821
-
Normalization of obesity-associated insulin resistance through immunotherapy
-
Winer S, Chan Y, Paltser G, et al., Normalization of obesity-associated insulin resistance through immunotherapy. Nat Med 2009; 15: 921-929.
-
(2009)
Nat Med
, vol.15
, pp. 921-929
-
-
Winer, S.1
Chan, Y.2
Paltser, G.3
-
26
-
-
84857985148
-
The cellular and signaling networks linking the immune system and metabolism in disease
-
Osborn O, Olefsky JM., The cellular and signaling networks linking the immune system and metabolism in disease. Nat Med 2012; 18: 363-374.
-
(2012)
Nat Med
, vol.18
, pp. 363-374
-
-
Osborn, O.1
Olefsky, J.M.2
-
27
-
-
68349148211
-
Lean, but not obese, fat is enriched for a unique population of regulatory T cells that affect metabolic parameters
-
Feuerer M, Herrero L, Cipolletta D, et al., Lean, but not obese, fat is enriched for a unique population of regulatory T cells that affect metabolic parameters. Nat Med 2009; 15: 930-939.
-
(2009)
Nat Med
, vol.15
, pp. 930-939
-
-
Feuerer, M.1
Herrero, L.2
Cipolletta, D.3
-
28
-
-
54049086276
-
Interferon-gamma, a Th1 cytokine, regulates fat inflammation: A role for adaptive immunity in obesity
-
Rocha VZ, Folco EJ, Sukhova G, et al., Interferon-gamma, a Th1 cytokine, regulates fat inflammation: A role for adaptive immunity in obesity. Circulation Res 2008; 103: 467-476.
-
(2008)
Circulation Res
, vol.103
, pp. 467-476
-
-
Rocha, V.Z.1
Folco, E.J.2
Sukhova, G.3
-
29
-
-
84872166765
-
Pleiotropic actions of insulin resistance and inflammation in metabolic homeostasis
-
Odegaard JI, Chawla A., Pleiotropic actions of insulin resistance and inflammation in metabolic homeostasis. Science 2013; 339: 172-177.
-
(2013)
Science
, vol.339
, pp. 172-177
-
-
Odegaard, J.I.1
Chawla, A.2
-
30
-
-
56749164791
-
Nutrient sensing and inflammation in metabolic diseases
-
Hotamisligil GS, Erbay E., Nutrient sensing and inflammation in metabolic diseases. Nature Rev Immunol 2008; 8: 923-934.
-
(2008)
Nature Rev Immunol
, vol.8
, pp. 923-934
-
-
Hotamisligil, G.S.1
Erbay, E.2
-
32
-
-
84878812591
-
Innate immune receptors: Key regulators of metabolic disease progression
-
Jin C, Henao-Mejia J, Flavell RA., Innate immune receptors: Key regulators of metabolic disease progression. Cell Metab 2013; 17: 873-882.
-
(2013)
Cell Metab
, vol.17
, pp. 873-882
-
-
Jin, C.1
Henao-Mejia, J.2
Flavell, R.A.3
-
33
-
-
34347399563
-
Metabolic endotoxemia initiates obesity and insulin resistance
-
Cani PD, Amar J, Iglesias MA, et al., Metabolic endotoxemia initiates obesity and insulin resistance. Diabetes 2007; 56: 1761-1772.
-
(2007)
Diabetes
, vol.56
, pp. 1761-1772
-
-
Cani, P.D.1
Amar, J.2
Iglesias, M.A.3
-
34
-
-
33750584214
-
TLR4 links innate immunity and fatty acid-induced insulin resistance
-
Shi H, Kokoeva MV, Inouye K, et al., TLR4 links innate immunity and fatty acid-induced insulin resistance. J Clin Investig 2006; 116: 3015-3025.
-
(2006)
J Clin Investig
, vol.116
, pp. 3015-3025
-
-
Shi, H.1
Kokoeva, M.V.2
Inouye, K.3
-
35
-
-
84855508991
-
Obesity activates toll-like receptor-mediated proinflammatory signaling cascades in the adipose tissue of mice
-
Kim SJ, Choi Y, Choi YH, et al., Obesity activates toll-like receptor-mediated proinflammatory signaling cascades in the adipose tissue of mice. J Nutr Biochem 2012; 23: 113-122.
-
(2012)
J Nutr Biochem
, vol.23
, pp. 113-122
-
-
Kim, S.J.1
Choi, Y.2
Choi, Y.H.3
-
36
-
-
77957108166
-
T cell recruitment and Th1 polarization in adipose tissue during diet-induced obesity in C57BL/6 mice
-
Strissel KJ, DeFuria J, Shaul ME, et al., T cell recruitment and Th1 polarization in adipose tissue during diet-induced obesity in C57BL/6 mice. Obesity 2010; 18: 1918-1925.
-
(2010)
Obesity
, vol.18
, pp. 1918-1925
-
-
Strissel, K.J.1
DeFuria, J.2
Shaul, M.E.3
-
37
-
-
0346157290
-
Innate immunity: An overview
-
8 59
-
Beutler B., Innate immunity: An overview. Mol Immunol 2004; 40: 845 -8 59.
-
(2004)
Mol Immunol
, vol.40
, pp. 845
-
-
Beutler, B.1
-
38
-
-
84866058423
-
TLR9 is important for protection against intestinal damage and for intestinal repair
-
Rose WA, 2nd, Sakamoto K, Leifer CA., TLR9 is important for protection against intestinal damage and for intestinal repair. Sci Rep 2012; 2: 574.
-
(2012)
Sci Rep
, vol.2
, pp. 574
-
-
Rose, W.A.1
Sakamoto, K.2
Leifer, C.A.3
-
39
-
-
33751563152
-
Macrophages and myeloid dendritic cells, but not plasmacytoid dendritic cells, produce IL-10 in response to MyD88- and TRIF-dependent TLR signals, and TLR-independent signals
-
Boonstra A, Rajsbaum R, Holman M, et al., Macrophages and myeloid dendritic cells, but not plasmacytoid dendritic cells, produce IL-10 in response to MyD88- and TRIF-dependent TLR signals, and TLR-independent signals. J Immunol 2006; 177: 7551-7558.
-
(2006)
J Immunol
, vol.177
, pp. 7551-7558
-
-
Boonstra, A.1
Rajsbaum, R.2
Holman, M.3
-
40
-
-
84866461477
-
Familial transmission rather than defective innate immunity shapes the distinct intestinal microbiota of TLR-deficient mice
-
Ubeda C, Lipuma L, Gobourne A, et al., Familial transmission rather than defective innate immunity shapes the distinct intestinal microbiota of TLR-deficient mice. J Exp Med 2012; 209: 1445-1456.
-
(2012)
J Exp Med
, vol.209
, pp. 1445-1456
-
-
Ubeda, C.1
Lipuma, L.2
Gobourne, A.3
|