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Volumn 26, Issue 11, 2006, Pages 2991-3001

The CB1 cannabinoid receptor is the major cannabinoid receptor at excitatory presynaptic sites in the hippocampus and cerebellum

Author keywords

Cannabinoid; CB1 receptor; Cerebellum; Excitatory synapse; Hippocampus; Presynaptic suppression; Purkinje cell; Pyramidal cell

Indexed keywords

1 (2,4 DICHLOROPHENYL) 5 (4 IODOPHENYL) 4 METHYL N (1 PIPERIDYL) 1H PYRAZOLE 3 CARBOXAMIDE; CANNABINOID 1 RECEPTOR; CANNABINOID RECEPTOR;

EID: 33644934527     PISSN: 02706474     EISSN: 02706474     Source Type: Journal    
DOI: 10.1523/JNEUROSCI.4872-05.2006     Document Type: Article
Times cited : (404)

References (54)
  • 1
    • 0036867665 scopus 로고    scopus 로고
    • Retrograde signaling in the regulation of synaptic transmission: Focus on endocannabinoids
    • Alger BE (2002) Retrograde signaling in the regulation of synaptic transmission: focus on endocannabinoids. Prog Neurobiol 68:247-286.
    • (2002) Prog Neurobiol , vol.68 , pp. 247-286
    • Alger, B.E.1
  • 2
    • 0037360828 scopus 로고    scopus 로고
    • Activation of the cannabinoid receptor type 1 decreases glutamatergic and GABAergic synaptic transmission in the lateral amygdala of the mouse
    • Azad SC, Eder M, Marsicano G, Lutz B, Zieglgansberger W, Rammes G (2003) Activation of the cannabinoid receptor type 1 decreases glutamatergic and GABAergic synaptic transmission in the lateral amygdala of the mouse. Learn Mem 10:116-128.
    • (2003) Learn Mem , vol.10 , pp. 116-128
    • Azad, S.C.1    Eder, M.2    Marsicano, G.3    Lutz, B.4    Zieglgansberger, W.5    Rammes, G.6
  • 4
    • 22544437266 scopus 로고    scopus 로고
    • Endocannabinoid signaling in rat somatosensory cortex: Laminar differences and involvement of specific interneuron types
    • Bodor AL, Katona I, Nyiri G, Mackie K, Ledent C, Hajos N, Freund TF (2005) Endocannabinoid signaling in rat somatosensory cortex: laminar differences and involvement of specific interneuron types. J Neurosci 25:6845-6856.
    • (2005) J Neurosci , vol.25 , pp. 6845-6856
    • Bodor, A.L.1    Katona, I.2    Nyiri, G.3    Mackie, K.4    Ledent, C.5    Hajos, N.6    Freund, T.F.7
  • 5
    • 0038043720 scopus 로고    scopus 로고
    • Calcium dependence of retrograde inhibition by endocannabinoids at synapses onto Purkinje cells
    • Brenowitz SD, Regehr WG (2003) Calcium dependence of retrograde inhibition by endocannabinoids at synapses onto Purkinje cells. J Neurosci 23:6373-6384.
    • (2003) J Neurosci , vol.23 , pp. 6373-6384
    • Brenowitz, S.D.1    Regehr, W.G.2
  • 6
    • 13244256986 scopus 로고    scopus 로고
    • Associative short-term synaptic plasticity mediated by endocannabinoids
    • Brenowitz SD, Regehr WG (2005) Associative short-term synaptic plasticity mediated by endocannabinoids. Neuron 45:419-431.
    • (2005) Neuron , vol.45 , pp. 419-431
    • Brenowitz, S.D.1    Regehr, W.G.2
  • 7
    • 0036139184 scopus 로고    scopus 로고
    • Short-term retrograde inhibition of GABAergic synaptic currents in rat Purkinje cells is mediated by endogenous cannabinoids
    • Diana MA, Levenes C, Mackie K, Marty A (2002) Short-term retrograde inhibition of GABAergic synaptic currents in rat Purkinje cells is mediated by endogenous cannabinoids. J Neurosci 22:200-208.
    • (2002) J Neurosci , vol.22 , pp. 200-208
    • Diana, M.A.1    Levenes, C.2    Mackie, K.3    Marty, A.4
  • 8
    • 0034717944 scopus 로고    scopus 로고
    • Localisation of cannabinoid receptors in the rat brain using antibodies to the intracellular C-terminal tail of CB
    • Egertova M, Elphick MR (2000) Localisation of cannabinoid receptors in the rat brain using antibodies to the intracellular C-terminal tail of CB. J Comp Neurol 422:159-171.
    • (2000) J Comp Neurol , vol.422 , pp. 159-171
    • Egertova, M.1    Elphick, M.R.2
  • 9
    • 0037661996 scopus 로고    scopus 로고
    • Role of endogenous cannabinoids in synaptic signaling
    • Freund TF, Katona I, Piomelli D (2003) Role of endogenous cannabinoids in synaptic signaling. Physiol Rev 83:1017-1066.
    • (2003) Physiol Rev , vol.83 , pp. 1017-1066
    • Freund, T.F.1    Katona, I.2    Piomelli, D.3
  • 11
    • 0344441319 scopus 로고    scopus 로고
    • Emerging roles for endocannabinoids in long-term synaptic plasticity
    • Gerdeman GL, Lovinger DM (2003) Emerging roles for endocannabinoids in long-term synaptic plasticity. Br J Pharmacol 140:781-789.
    • (2003) Br J Pharmacol , vol.140 , pp. 781-789
    • Gerdeman, G.L.1    Lovinger, D.M.2
  • 12
    • 0036233834 scopus 로고    scopus 로고
    • Postsynaptic endocannabinoid release is critical to long-term depression in the striatum
    • Gerdeman GL, Ronesi J, Lovinger DM (2002) Postsynaptic endocannabinoid release is critical to long-term depression in the striatum. Nat Neurosci 5:446-451.
    • (2002) Nat Neurosci , vol.5 , pp. 446-451
    • Gerdeman, G.L.1    Ronesi, J.2    Lovinger, D.M.3
  • 13
    • 0036753757 scopus 로고    scopus 로고
    • Pharmacological separation of cannabinoid-sensitive receptors on hippocampal excitatory and inhibitory fibers
    • Hajos N, Freund TF (2002a) Pharmacological separation of cannabinoid-sensitive receptors on hippocampal excitatory and inhibitory fibers. Neuropharmacology 43:503-510.
    • (2002) Neuropharmacology , vol.43 , pp. 503-510
    • Hajos, N.1    Freund, T.F.2
  • 14
    • 0037207070 scopus 로고    scopus 로고
    • Distinct cannabinoid-sensitive receptors regulate hippocampal excitation and inhibition
    • Hajos N, Freund TF (2002b) Distinct cannabinoid-sensitive receptors regulate hippocampal excitation and inhibition. Chem Phys Lipids 121:73-82.
    • (2002) Chem Phys Lipids , vol.121 , pp. 73-82
    • Hajos, N.1    Freund, T.F.2
  • 16
    • 0035801320 scopus 로고    scopus 로고
    • Novel cannabinoid-sensitive receptor mediates inhibition of glutamatergic synaptic transmission in the hippocampus
    • Hajos N, Ledent C, Freund TF (2001) Novel cannabinoid-sensitive receptor mediates inhibition of glutamatergic synaptic transmission in the hippocampus. Neuroscience 106:1-4.
    • (2001) Neuroscience , vol.106 , pp. 1-4
    • Hajos, N.1    Ledent, C.2    Freund, T.F.3
  • 18
    • 4644280012 scopus 로고    scopus 로고
    • Dendritically released transmitters cooperate via autocrine and retrograde actions to inhibit afferent excitation in rat brain
    • Lond
    • Hirasawa M, Schwab Y, Natah S, Hillard CJ, Mackie K, Sharkey KA, Pittman QJ (2004) Dendritically released transmitters cooperate via autocrine and retrograde actions to inhibit afferent excitation in rat brain. J Physiol (Lond) 559:611-624.
    • (2004) J Physiol , vol.559 , pp. 611-624
    • Hirasawa, M.1    Schwab, Y.2    Natah, S.3    Hillard, C.J.4    Mackie, K.5    Sharkey, K.A.6    Pittman, Q.J.7
  • 19
    • 27844492824 scopus 로고    scopus 로고
    • Species and strain differences in the expression of a novel glutamate-modulating cannabinoid receptor in the rodent hippocampus
    • Hoffman AF, Macgill AM, Smith D, Oz M, Lupica CR (2005) Species and strain differences in the expression of a novel glutamate-modulating cannabinoid receptor in the rodent hippocampus. Eur J Neurosci 22:2387-2391.
    • (2005) Eur J Neurosci , vol.22 , pp. 2387-2391
    • Hoffman, A.F.1    Macgill, A.M.2    Smith, D.3    Oz, M.4    Lupica, C.R.5
  • 24
    • 0345621691 scopus 로고    scopus 로고
    • Presynaptically located CB1 cannabinoid receptors regulate GABA release from axon terminals of specific hippocampal interneurons
    • Katona I, Sperlagh B, Sik A, K←falvi A, Vizi ES, Mackie K, Freund TF (1999) Presynaptically located CB1 cannabinoid receptors regulate GABA release from axon terminals of specific hippocampal interneurons. J Neurosci 19:4544-4558.
    • (1999) J Neurosci , vol.19 , pp. 4544-4558
    • Katona, I.1    Sperlagh, B.2    Sik, A.3    Kfalvi, A.4    Vizi, E.S.5    Mackie, K.6    Freund, T.F.7
  • 25
    • 0035576023 scopus 로고    scopus 로고
    • Distribution of CB1 cannabinoid receptors in the amygdala and their role in the control of GABAergic transmission
    • Katona I, Rancz EA, Acsady L, Ledent C, Mackie K, Hajos N, Freund TF (2001) Distribution of CB1 cannabinoid receptors in the amygdala and their role in the control of GABAergic transmission. J Neurosci 21:9506-9518.
    • (2001) J Neurosci , vol.21 , pp. 9506-9518
    • Katona, I.1    Rancz, E.A.2    Acsady, L.3    Ledent, C.4    Mackie, K.5    Hajos, N.6    Freund, T.F.7
  • 26
    • 0242539727 scopus 로고    scopus 로고
    • 3H]glutamate from rodent hippocampal synaptosomes via a novel CB1 receptor-independent action
    • 3H]glutamate from rodent hippocampal synaptosomes via a novel CB1 receptor-independent action. Eur J Neurosci 18:1973-1978.
    • (2003) Eur J Neurosci , vol.18 , pp. 1973-1978
    • Kofalvi, A.1    Vizi, E.S.2    Ledent, C.3    Sperlagh, B.4
  • 27
    • 15244356828 scopus 로고    scopus 로고
    • Involvement of cannabinoid receptors in the regulation of neurotransmitter release in the rodent striatum: A combined immunochemical and pharmacological analysis
    • Kofalvi A, Rodrigues RJ, Ledent C, Mackie K, Vizi ES, Cunha RA, Sperlagh B (2005) Involvement of cannabinoid receptors in the regulation of neurotransmitter release in the rodent striatum: a combined immunochemical and pharmacological analysis. J Neurosci 25:2874-2884.
    • (2005) J Neurosci , vol.25 , pp. 2874-2884
    • Kofalvi, A.1    Rodrigues, R.J.2    Ledent, C.3    Mackie, K.4    Vizi, E.S.5    Cunha, R.A.6    Sperlagh, B.7
  • 28
    • 0035888999 scopus 로고    scopus 로고
    • Cerebellar depolarization-induced suppression of inhibition is mediated by endogenous cannabinoids
    • 1-5
    • Kreitzer AC, Regehr WG (2001a) Cerebellar depolarization-induced suppression of inhibition is mediated by endogenous cannabinoids. J Neurosci 21:RC174(1-5).
    • (2001) J Neurosci , vol.21
    • Kreitzer, A.C.1    Regehr, W.G.2
  • 29
    • 0035053627 scopus 로고    scopus 로고
    • Retrograde inhibition of presynaptic calcium influx by endogenous cannabinoids at excitatory synapses onto Purkinje cells
    • Kreitzer AC, Regehr WG (2001b) Retrograde inhibition of presynaptic calcium influx by endogenous cannabinoids at excitatory synapses onto Purkinje cells. Neuron 29:717-727.
    • (2001) Neuron , vol.29 , pp. 717-727
    • Kreitzer, A.C.1    Regehr, W.G.2
  • 30
    • 0346094445 scopus 로고    scopus 로고
    • Differential effects of the sleep-inducing lipid oleamide and cannabinoids on the induction of long-term potentiation in the CA1 neurons of the rat hippocampus in vitro
    • Lees G, Dougalis A (2004) Differential effects of the sleep-inducing lipid oleamide and cannabinoids on the induction of long-term potentiation in the CA1 neurons of the rat hippocampus in vitro. Brain Res 997:1-14.
    • (2004) Brain Res , vol.997 , pp. 1-14
    • Lees, G.1    Dougalis, A.2
  • 31
    • 0030704241 scopus 로고    scopus 로고
    • Differential plasma membrane distribution of metabotropic glutamate receptor mGluR1α, mGluR2, and mGluR5, relative to neurotransmitter release sites
    • Lujan R, Roberts JDB, Shigemoto R, Ohishi H, Somogyi P (1997) Differential plasma membrane distribution of metabotropic glutamate receptor mGluR1α, mGluR2, and mGluR5, relative to neurotransmitter release sites. J Chem Neuroanat 13:219-241.
    • (1997) J Chem Neuroanat , vol.13 , pp. 219-241
    • Lujan, R.1    Roberts, J.D.B.2    Shigemoto, R.3    Ohishi, H.4    Somogyi, P.5
  • 32
    • 0035899382 scopus 로고    scopus 로고
    • Presynaptic inhibition caused by retrograde signal from metabotropic glutamate to cannabinoid receptors
    • Maejima T, Hashimoto K, Yoshida T, Aiba A, Kano M (2001) Presynaptic inhibition caused by retrograde signal from metabotropic glutamate to cannabinoid receptors. Neuron 31:463-475.
    • (2001) Neuron , vol.31 , pp. 463-475
    • Maejima, T.1    Hashimoto, K.2    Yoshida, T.3    Aiba, A.4    Kano, M.5
  • 34
    • 0033452718 scopus 로고    scopus 로고
    • Expression of the cannabinoid receptor CB1 in distinct neuronal subpopulations in the adult mouse forebrain
    • Marsicano G, Lutz B (1999) Expression of the cannabinoid receptor CB1 in distinct neuronal subpopulations in the adult mouse forebrain. Eur J Neurosci 11:4213-4225.
    • (1999) Eur J Neurosci , vol.11 , pp. 4213-4225
    • Marsicano, G.1    Lutz, B.2
  • 35
    • 0025325535 scopus 로고
    • Structure of a cannabinoid receptor and functional expression of the cloned cDNA
    • Matsuda LA, Lolait SJ, Brownstein MJ, Young AC, Bonner TI (1990) Structure of a cannabinoid receptor and functional expression of the cloned cDNA. Nature 346:561-564.
    • (1990) Nature , vol.346 , pp. 561-564
    • Matsuda, L.A.1    Lolait, S.J.2    Brownstein, M.J.3    Young, A.C.4    Bonner, T.I.5
  • 36
    • 3042810397 scopus 로고    scopus 로고
    • Immunocytochemically defined interneuron populations in the hippocampus of mouse strains used in transgenic technology
    • Matyas F, Freund TF, Gulyas AI (2004) Immunocytochemically defined interneuron populations in the hippocampus of mouse strains used in transgenic technology. Hippocampus 14:460-481.
    • (2004) Hippocampus , vol.14 , pp. 460-481
    • Matyas, F.1    Freund, T.F.2    Gulyas, A.I.3
  • 38
    • 0038008179 scopus 로고    scopus 로고
    • Subtype switching of vesicular glutamate transporters at parallel fibre-Purkinje cell synapses in developing mouse cerebellum
    • Miyazaki T, Fukaya M, Shimizu H, Watanabe M (2003) Subtype switching of vesicular glutamate transporters at parallel fibre-Purkinje cell synapses in developing mouse cerebellum. Eur J Neurosci 17:2563-2572.
    • (2003) Eur J Neurosci , vol.17 , pp. 2563-2572
    • Miyazaki, T.1    Fukaya, M.2    Shimizu, H.3    Watanabe, M.4
  • 39
    • 0027515373 scopus 로고
    • Molecular characterization of a peripheral receptor for cannabinoids
    • Munro S, Thomas KL, Abu-Shaar M (1993) Molecular characterization of a peripheral receptor for cannabinoids. Nature 365:61-65.
    • (1993) Nature , vol.365 , pp. 61-65
    • Munro, S.1    Thomas, K.L.2    Abu-Shaar, M.3
  • 40
    • 10844229395 scopus 로고    scopus 로고
    • Signaling complex formation of phospholipase Cβ4 with metabotropic glutamate receptor type 1α and 1,4,5-trisphosphate receptor at the perisynapse and endoplasmic reticulum in the mouse brain
    • Nakamura M, Sato K, Fukaya M, Araishi K, Aiba A, Kano M, Watanabe M (2004) Signaling complex formation of phospholipase Cβ4 with metabotropic glutamate receptor type 1α and 1,4,5-trisphosphate receptor at the perisynapse and endoplasmic reticulum in the mouse brain. Eur J Neurosci 20:2929-2944.
    • (2004) Eur J Neurosci , vol.20 , pp. 2929-2944
    • Nakamura, M.1    Sato, K.2    Fukaya, M.3    Araishi, K.4    Aiba, A.5    Kano, M.6    Watanabe, M.7
  • 41
    • 0036455218 scopus 로고    scopus 로고
    • Cooperative endocannabinoid production by neuronal depolarization and group I metabotropic glutamate receptor activation
    • Ohno-Shosaku T, Shosaku J, Tsubokawa H, Kano M (2002a) Cooperative endocannabinoid production by neuronal depolarization and group I metabotropic glutamate receptor activation. Eur J Neurosci 15:953-961.
    • (2002) Eur J Neurosci , vol.15 , pp. 953-961
    • Ohno-Shosaku, T.1    Shosaku, J.2    Tsubokawa, H.3    Kano, M.4
  • 42
    • 0037095762 scopus 로고    scopus 로고
    • Presynaptic cannabinoid sensitivity is a major determinant of depolarization-induced retrograde suppression at hippocampal synapses
    • Ohno-Shosaku T, Tsubokawa H, Mizushima I, Yoneda N, Zimmer A, Kano M (2002b) Presynaptic cannabinoid sensitivity is a major determinant of depolarization-induced retrograde suppression at hippocampal synapses. J Neurosci 22:3864-3872.
    • (2002) J Neurosci , vol.22 , pp. 3864-3872
    • Ohno-Shosaku, T.1    Tsubokawa, H.2    Mizushima, I.3    Yoneda, N.4    Zimmer, A.5    Kano, M.6
  • 43
    • 24644450658 scopus 로고    scopus 로고
    • Calcium signaling and synaptic modulation: Regulation of endocannabinoid-mediated synaptic modulation by calcium
    • Ohno-Shosaku T, Hashimotodani Y, Maejima T, Kano M (2005) Calcium signaling and synaptic modulation: regulation of endocannabinoid-mediated synaptic modulation by calcium. Cell Calcium 38:369-374.
    • (2005) Cell Calcium , vol.38 , pp. 369-374
    • Ohno-Shosaku, T.1    Hashimotodani, Y.2    Maejima, T.3    Kano, M.4
  • 44
    • 0037062421 scopus 로고    scopus 로고
    • Endogenous cannabinoids mediate long-term synaptic depression in the nucleus accumbens
    • USA
    • Robbe D, Kopf M, Remaury A, Bockaert J, Manzoni OJ (2002) Endogenous cannabinoids mediate long-term synaptic depression in the nucleus accumbens. Proc Natl Acad Sci USA 99:8384-8388.
    • (2002) Proc Natl Acad Sci , vol.99 , pp. 8384-8388
    • Robbe, D.1    Kopf, M.2    Remaury, A.3    Bockaert, J.4    Manzoni, O.J.5
  • 45
    • 0030724776 scopus 로고    scopus 로고
    • Glutamate transporter GLAST is expressed in the radial glia-astrocyte lineage of developing mouse spinal cord
    • Shibata T, Yamada K, Watanabe M, Ikenaka K, Wada K, Tanaka K, Inoue Y (1997) Glutamate transporter GLAST is expressed in the radial glia-astrocyte lineage of developing mouse spinal cord. J Neurosci 17:9212-9219.
    • (1997) J Neurosci , vol.17 , pp. 9212-9219
    • Shibata, T.1    Yamada, K.2    Watanabe, M.3    Ikenaka, K.4    Wada, K.5    Tanaka, K.6    Inoue, Y.7
  • 46
    • 23944475831 scopus 로고    scopus 로고
    • Inhibition of cyclooxygenase-2 elicits a CB1-mediated decrease of excitatory transmission in rat CA1 hippocampus
    • Slanina KA, Schweitzer P (2005) Inhibition of cyclooxygenase-2 elicits a CB1-mediated decrease of excitatory transmission in rat CA1 hippocampus. Neuropharmacology 49:653-659.
    • (2005) Neuropharmacology , vol.49 , pp. 653-659
    • Slanina, K.A.1    Schweitzer, P.2
  • 47
    • 29244449844 scopus 로고    scopus 로고
    • Depolarisation-induced suppression of excitation in murine autaptic hippocampal neurons
    • Lond
    • Straiker A, Mackie K (2005) Depolarisation-induced suppression of excitation in murine autaptic hippocampal neurons. J Physiol (Lond) 569:501-517.
    • (2005) J Physiol , vol.569 , pp. 501-517
    • Straiker, A.1    Mackie, K.2
  • 48
    • 0034235155 scopus 로고    scopus 로고
    • Calcium-dependent persistent facilitation of spike backpropagation in the CA1 pyramidal neurons
    • Tsubokawa H, Offermanns S, Simon M, Kano M (2000) Calcium-dependent persistent facilitation of spike backpropagation in the CA1 pyramidal neurons. J Neurosci 20:4878-4884.
    • (2000) J Neurosci , vol.20 , pp. 4878-4884
    • Tsubokawa, H.1    Offermanns, S.2    Simon, M.3    Kano, M.4
  • 49
    • 0035893233 scopus 로고    scopus 로고
    • Metabotropic glutamate receptors drive the endocannabinoid system in hippocampus
    • 1-5
    • Varma N, Carlson GC, Ledent C, Alger BE (2001) Metabotropic glutamate receptors drive the endocannabinoid system in hippocampus. J Neurosci 21:RC188(1-5).
    • (2001) J Neurosci , vol.21
    • Varma, N.1    Carlson, G.C.2    Ledent, C.3    Alger, B.E.4
  • 50
    • 3242661071 scopus 로고    scopus 로고
    • A novel component of cannabis extract potentiates excitatory synaptic transmission in rat olfactory cortex in vitro
    • Whalley BJ, Wilkinson JD, Williamson EM, Constanti A (2004) A novel component of cannabis extract potentiates excitatory synaptic transmission in rat olfactory cortex in vitro. Neurosci Lett 365:58-63.
    • (2004) Neurosci Lett , vol.365 , pp. 58-63
    • Whalley, B.J.1    Wilkinson, J.D.2    Williamson, E.M.3    Constanti, A.4
  • 51
    • 0037207074 scopus 로고    scopus 로고
    • Cannabinoid pharmacology: Implications for additional cannabinoid receptor subtypes
    • Wiley JL, Martin BR (2002) Cannabinoid pharmacology: implications for additional cannabinoid receptor subtypes. Chem Phys Lipids 121:57-63.
    • (2002) Chem Phys Lipids , vol.121 , pp. 57-63
    • Wiley, J.L.1    Martin, B.R.2
  • 52
    • 0035899302 scopus 로고    scopus 로고
    • Presynaptic specificity of endocannabinoid signaling in the hippocampus
    • Wilson RI, Kunos G, Nicoll RA (2001) Presynaptic specificity of endocannabinoid signaling in the hippocampus. Neuron 31:453-462.
    • (2001) Neuron , vol.31 , pp. 453-462
    • Wilson, R.I.1    Kunos, G.2    Nicoll, R.A.3
  • 53
    • 0036523103 scopus 로고    scopus 로고
    • The cannabinoid CB1 receptor mediates retrograde signals for depolarization-induced suppression of inhibition in cerebellar Purkinje cells
    • Yoshida T, Hashimoto K, Zimmer A, Maejima T, Araishi K, Kano M (2002) The cannabinoid CB1 receptor mediates retrograde signals for depolarization-induced suppression of inhibition in cerebellar Purkinje cells. J Neurosci 22:1690-1697.
    • (2002) J Neurosci , vol.22 , pp. 1690-1697
    • Yoshida, T.1    Hashimoto, K.2    Zimmer, A.3    Maejima, T.4    Araishi, K.5    Kano, M.6
  • 54
    • 0033545866 scopus 로고    scopus 로고
    • Increased mortality, hypoactivity, and hypoalgesia in cannabinoid CB1 receptor knock-out mice
    • USA
    • Zimmer A, Zimmer AM, Hohmann AG, Herkenham M, Bonner TI (1999) Increased mortality, hypoactivity, and hypoalgesia in cannabinoid CB1 receptor knock-out mice. Proc Natl Acad Sci USA 96:5780-5785.
    • (1999) Proc Natl Acad Sci , vol.96 , pp. 5780-5785
    • Zimmer, A.1    Zimmer, A.M.2    Hohmann, A.G.3    Herkenham, M.4    Bonner, T.I.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.