Hot melt extrusion: An industrially feasible approach for casting orodispersible film

Asian Journal of Pharmaceutical Sciences

Volumn 10, Issue 4, 2014, Pages 292-305

  Jani, Rushiraj ^a,b   Patel, Dasharath ^b  

^a RK UNIVERSITY   (India)

^b Shri Sarvajanik Pharmacy College   (India)

Author keywords

Die swell phenomenon; Extruders; Film forming polymers; Plasticizers; Quality by design; Scale up

Indexed keywords

ADHESIVE AGENT; ALCOHOL; ALPHA TOCOPHEROL; ALPHA TOCOPHEROL SUCCINATE; ANTIOXIDANT; CITRIC ACID TRIETHYL ESTER; DEXTROMETHORPHAN; EUDRAGIT; EXCIPIENT; HYDROXYPROPYLCELLULOSE; HYDROXYPROPYLMETHYLCELLULOSE; LACTITOL; MACROGOL; MACROGOL 6000; MALTITOL; MALTODEXTRIN; MANNITOL; MICROCRYSTALLINE CELLULOSE; PLASTICIZER; POLYACRYLIC ACID; POLYMER; PULLULAN; SILICON DIOXIDE; SOLVENT; SORBITOL; STARCH; SUGAR ALCOHOL; SWEETENING AGENT; TITANIUM DIOXIDE; XYLITOL;

CONTINUOUS PROCESS; CRYSTALLIZATION; DISPERSION; DOWNSTREAM PROCESSING; DRUG DOSAGE FORM; DRUG FORMULATION; DRUG IMPURITY; DRUG INDUSTRY; DRUG MANUFACTURE; DRUG SOLUBILITY; DRUG STABILITY; FILM; FLAVOR; GLASS TRANSITION TEMPERATURE; HOT MELT EXTRUSION; LABORATORY; LIQUID; MELTING POINT; MOISTURE; MOLECULAR WEIGHT; ORODISPERSIBLE FILM FORMULATION; OXIDATION; POWDER; PRESSURE; PROCESS OPTIMIZATION; PRODUCT DEVELOPMENT; REVIEW; RISK ASSESSMENT; SCALE UP; SHEAR RATE; SIMULATION; TEMPERATURE;

EID: 84946488702     PISSN: 18180876     EISSN: 2221285X     Source Type: Journal    
DOI: 10.1016/j.ajps.2015.03.002     Document Type: Review

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