Role of taste and taste masking of bitter drugs in pharmaceutical industriesan overview

International Journal of Pharmacy and Pharmaceutical Sciences

Volumn 2, Issue SUPPL. 4, 2010, Pages 14-18

  Sharma, Vijay ^a   Chopra, Himanshu ^b  

^a PRIST UNIVERSITY   (India)

^b GRD ^*  (United Kingdom)

Author keywords

And polymers; Drugs; Taste; Taste buds; Taste masking

Indexed keywords

ARTEMETHER; CHLORAMPHENICOL; CIPROFLOXACIN; CLINDAMYCIN; DICLOFENAC; DIPHENHYDRAMINE; HYDROXYPROPYLMETHYLCELLULOSE; IBUPROFEN; INDELOXAZINE; LEVAMISOLE; LIPOSOME; NIMESULIDE; NORFLOXACIN; OFLOXACIN; ONDANSETRON; POLYLACTIC ACID; POLYMER; POVIDONE; PROPRANOLOL; QUININE; QUININE SULFATE; RANITIDINE; ROFECOXIB; SPARFLOXACIN; TERFENADINE; TRAMADOL; TRIAMCINOLONE;

ARTICLE; BITTER TASTE; DRUG COATING; DRUG DOSAGE FORM; DRUG FORMULATION; DRUG INDUSTRY; DRUG RELEASE; DRUG SOLUBILITY; DRUG STABILITY; EMULSION; INFRARED SPECTROSCOPY; ION EXCHANGE; MICROENCAPSULATION; PHYSICAL CHEMISTRY; SCANNING ELECTRON MICROSCOPY; SPRAY DRYING; SWEETNESS; TASTE BUD;

EID: 78649753200     PISSN: 09751491     EISSN: 09751491     Source Type: Journal    
DOI: None     Document Type: Article

References (40)

1. Encyclopedia Britannica. 2009
2. Huang A.L., The cells and logic for mammalian sour taste detection", nature, 442. 934-938 (2006).
3. Scenta. "How sour taste buds grow", August 28, 2006.
4. Collings V.B., Taste response as a function of locus of stimulation on the tongues and soft palate. 16, 169-174
5. Cooper R.M., The Effect Of Age On Taste Sensitivity, J Gerontology (1959) 14(1): 56-58
6. Test the Taste buds, Science and Nature.com
7. Parul B. Patel, Fast Dissolving Drug Delivery System; An update, Pharmainfo.net, 2006, Vol. 4, Issue 6.
8. Pokharkar V. B., Kshrisaga S. J., Fatima L.; Taste Masking of Pharmaceuticals, Pharmainfo.net, 2005, vol. 3, issue 2
9. Sohi H., Sultana Y., and. Khar R.; Taste Masking Technologies in Oral Pharmaceuticals: Recent Developments and Approaches, Drug Dev and Ind Pharm, 2004; Volume 30 (5): 429-448.
10. Gohel M, Patel M, Amin A, Agrawal R, Dave R, Bariya N. Formulation Design and Optimization of Mouth Dissolve Tablets of Nimesulide Using Vacuum Drying Technique. AAPS PharmSciTech. 2004; 5(3): article 36.
11. Dandagi P.M., Sreeenivas S.A., Manvi F.V., Patil M.B., Mastiholimath V.S. and Gadad A.P.; Taste masked ofloxacin mouth disintegrating tablets, Indian Drugs, 2005; 42(1): 52-55
12. Sugao H., Taste masking of bitter drug powder without loss of bioavailability by heat treatment of wax-coated microparticles. Journal of Microencapsulation 1999, Vol. 16, No. 5, Pages 565-571.
13. Mauger J.W., Robinson J.R. and Dennis H., US Patent, 1998, 5,728,403 Shen R. W. US Patent, 1996, 5,552152.
14. Davis J.d.; Drug Cosmet. India; Encyclopedia of Pharmaceutical Technology, Volume 2 (2000)
15. Shirai Y., Sogo K., Yammamoto K., Kojimai K.,;A novel fine granule system for masking bitter taste. Boil pharm bull, Feb 1993, Volume 16(2); 172-177.
16. Gedam S.S, Tapar K. K, Taste masking and characterization of diphenhydramine hydrochloride by spray drying technique. Int. Jour. Of Pharmaceutical Research, February - 2010, volume 1, issue - 12, article-3.
17. Biradar S. S., Bhagavati S. T., Kuppasad I. J.; Fast Dissolving Drug Delivery Systems: A Brief Overview. The Int. J of P'cology. 2006; Volume 4 (2).
18. Shreenivas S.A., Gadad A.P., Dandagi P.m., Patil M.B., Formulation and evaluation of ondensetron HCl Directly compression mouth disintegrating tablet. Indian Drugs 2006, Vol.43/1, 35-38
19. Shirai Y., Sogo K., Yammamoto K., kojimai K.,;A novel fine granule system for masking bitter taste. Boil Pharma bull, Feb 1993, Volume 16(2); 172-177.
20. Ion-Exchange Resin, www.corelpharmachem.com
21. Hughes L.; New uses of Ion Exchange Resin in Pharmaceutical Formulation, Rohm & Haas Research Laboratories., Pharm. Technology Excipients & solid dosage forms, 2004
22. Khan S, Guha A. Katariya P, Strong cation exchange resin for improving physicochemical properties and sustaining release of ranitidine hydrochloride 2007,Vol. 69, Issue 5,Page 626-632.
23. Madgulkar A.R., Bhalekar Formulation Design and Optimization of Novel Taste Masked Mouth-Dissolving Tablets of Tramadol Having Adequate Mechanical Strength, AAPS PharmSciTech, Volume 10, Number 2/June, 2009,574-581
24. Rao, C, Motiwale, A, Satyanarayana, D, Subrahmanyam, E, Formulation of taste masked oral suspension of quinine sulphate by complexation, International Juor. Pharm Sci, 2004, Vol 66, issue 3, 329-331
25. Bhise K, Shaikh S., Bora D. 1Taste Mask, Design and Evaluation of an Oral Formulation Using Ion Exchange Resin as Drug Carrier. AAPS PharmSciTech,Volume 9, 2008,557-562
26. Cotterill J.V., Massei G., Cowan D.P; Masking the bitter taste of conditioned taste levamisole using ion-exchange resin, for practical application in wild life management, Pest Manag Sci., 2006; Volume 62(2):120-12
27. Bhelakar M., Madgukkar A., Avari J.G.; Preparation and evaluation of taste masked resinates of ranitidine HCl. Int. J Pharm Exci, 2005:95-98.
28. Pisal S, Zainnuddin R.; Molecular properties of Ciprofloxacin-Indion 234 Complexes. AAPS Pharma SciTech., 2004; Volume 5(4), Article 62
29. Pandya S.P, Compatible Polymer used as complexes in various drug delivery systems: β-Cyclodextrin, Pharmainfo.net, Vol. 6, Issue 2, 2008,
30. Challa R., Alka Ahuja, Javed Ali and R.K.Khar, cyclodextrin in drug delivery, AAPS pharmSciTech, Jan 26, 2005
31. Sanghavi N. M, Mayekar R, Fruitwalam., Inclusion Complexes of Terfenadine-Cyclodextrins, Drug Development and Industrial Pharmacy 1995, Vol. 21, No. 3, Pages 375-381
32. Sajal J.K., Taste masking in pharmaceuticals, An update, Journal of pharmacy research, vol 1, issue 2, 2008, 126-130.
33. Shah T. J. Amin A. F., Parikh J. R., Rajesh H. Parikh R. H Process optimization and characterizations of poloxamer solid dispersions of a poorly water-soluble drug., AAPS PharmSciTech,Volume 8,no. 2,June,2007 E18-E24,
34. Punit Shah and Rajashree C. Mashru, Development and Evaluation of Artemether Taste Masked Rapid Disintegrating Tablets with Improved Dissolution Using Solid Dispersion Technique., AAPS PharmSciTech, Vol. 9, No. 2, June 2008
35. Pokharkar V. B., Kshrisaga S. J., Fatima L.; Taste Masking of Pharmaceuticals, Pharmainfo.net, 2005, vol. 3, issue 2
36. Sohi H., Sultana Y., and. Khar R.; Taste Masking Technologies in Oral Pharmaceuticals: Recent Developments and Approaches, Drug Dev and Ind Pharm, 2004; Volume 30 (5): 429-448.
37. A-lOmran M. F.; Al-Suwayeh S. A., El-Helw A. M., Saleh S. I; Taste masking of diclofenac sodium using microencapsulation, Journal of Microencapsulation, 2002; Volume 19(1): 45-52(8).
38. Uchida T. Yoshida, K. and Goto S., Preparation and characterization of polylactic acid microspheres containing water-soluble dyes using a novel w/o/w emulsion solvent evaporation method. Journal of Microencapsulation, 1996, Vol. 13, No. 2, Pages 219-228,
39. Wien T., Redelmier T., Av-Gay,development of liposome's formation of ethambutol. Antimicrobial agents and chemotherapy May 2004.p-1887-1888.
40. Chatap V. K, Gupta V. B., Sharma D. K., Nandgude T. D. A Review On Taste Masking Methods For Bitter Drug, Pharmainfo.net, 2007, Vol. 5, Issue 4,